- Home
- Publications
- Publication Search
- Publication Details
Title
Lipid metabolism and lipid signals in aging and longevity
Authors
Keywords
lipid metabolism, lipid signals, aging, longevity
Journal
DEVELOPMENTAL CELL
Volume 56, Issue 10, Pages 1394-1407
Publisher
Elsevier BV
Online
2021-04-23
DOI
10.1016/j.devcel.2021.03.034
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- mTOR at the nexus of nutrition, growth, ageing and disease
- (2020) Grace Y. Liu et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- UPRER promotes lipophagy independent of chaperones to extend life span
- (2020) Joseph R. Daniele et al. Science Advances
- Olfactory specificity regulates lipid metabolism through neuroendocrine signaling in Caenorhabditis elegans
- (2020) Ayse Sena Mutlu et al. Nature Communications
- Spectroscopic coherent Raman imaging of Caenorhabditis elegans reveals lipid particle diversity
- (2020) Wei-Wen Chen et al. Nature Chemical Biology
- Pharmacological convergence reveals a lipid pathway that regulates C. elegans lifespan
- (2019) Alice L. Chen et al. Nature Chemical Biology
- Lysosomal Signaling Promotes Longevity by Adjusting Mitochondrial Activity
- (2019) Prasanna V. Ramachandran et al. DEVELOPMENTAL CELL
- Neuron-Astrocyte Metabolic Coupling Protects against Activity-Induced Fatty Acid Toxicity
- (2019) Maria S. Ioannou et al. CELL
- The role of lipids in aging-related metabolic changes
- (2019) Irene de Diego Tamayo et al. CHEMISTRY AND PHYSICS OF LIPIDS
- Gi/o-Protein Coupled Receptors in the Aging Brain
- (2019) Patrícia G. de Oliveira et al. Frontiers in Aging Neuroscience
- Structural characterization of life-extending Caenorhabditis elegans Lipid Binding Protein 8
- (2019) Matthew C. Tillman et al. Scientific Reports
- XBP-1 Remodels Lipid Metabolism to Extend Longevity
- (2019) Soudabeh Imanikia et al. Cell Reports
- ATGL-1 mediates the effect of dietary restriction and the insulin/IGF-1 signaling pathway on longevity in C. elegans
- (2019) Nava Zaarur et al. Molecular Metabolism
- TOR Signaling in Caenorhabditis elegans Development, Metabolism, and Aging
- (2019) T. Keith Blackwell et al. GENETICS
- Glucagon-Like Peptide-1: A Focus on Neurodegenerative Diseases
- (2019) Maddalena Grieco et al. Frontiers in Neuroscience
- Muscle-Specific Lipid Hydrolysis Prolongs Lifespan through Global Lipidomic Remodeling
- (2019) Sebastian Schmeisser et al. Cell Reports
- Exploring GPCR–Lipid Interactions by Molecular Dynamics Simulations: Excitements, Challenges, and the Way Forward
- (2018) Durba Sengupta et al. JOURNAL OF PHYSICAL CHEMISTRY B
- Lithocholic Acid Improves the Survival of Drosophila Melanogaster
- (2018) Stefanie Staats et al. MOLECULAR NUTRITION & FOOD RESEARCH
- Methionine Restriction Extends Lifespan in Progeroid Mice and Alters Lipid and Bile Acid Metabolism
- (2018) Clea Bárcena et al. Cell Reports
- Drosophila HNF4 Directs a Switch in Lipid Metabolism that Supports the Transition to Adulthood
- (2018) Gilles Storelli et al. DEVELOPMENTAL CELL
- Mono-unsaturated fatty acids link H3K4me3 modifiers to C. elegans lifespan
- (2017) Shuo Han et al. NATURE
- Microbial metabolites regulate host lipid metabolism through NR5A–Hedgehog signalling
- (2017) Chih-Chun Janet Lin et al. NATURE CELL BIOLOGY
- Rapid immunopurification of mitochondria for metabolite profiling and absolute quantification of matrix metabolites
- (2017) Walter W Chen et al. Nature Protocols
- Lysosomal metabolomics reveals V-ATPase- and mTOR-dependent regulation of amino acid efflux from lysosomes
- (2017) Monther Abu-Remaileh et al. SCIENCE
- High-throughput screens using photo-highlighting discover BMP signaling in mitochondrial lipid oxidation
- (2017) Yong Yu et al. Nature Communications
- Uncoupling of Metabolic Health from Longevity through Genetic Alteration of Adipose Tissue Lipid-Binding Proteins
- (2017) Khanichi N. Charles et al. Cell Reports
- The Brain Metabolome of Male Rats across the Lifespan
- (2016) Xiaojiao Zheng et al. Scientific Reports
- An Energy-Independent Pro-longevity Function of Triacylglycerol in Yeast
- (2016) Witawas Handee et al. PLoS Genetics
- Modulation of lipid biosynthesis contributes to stress resistance and longevity of C. elegans mutants
- (2016) Robert J. Shmookler Reis et al. Aging-US
- Deficiency of the lipid synthesis enzyme, DGAT1, extends longevity in mice
- (2016) Ryan S. Streeper et al. Aging-US
- Serum profiling of healthy aging identifies phospho- and sphingolipid species as markers of human longevity
- (2016) Ivan Montoliu et al. Aging-US
- Autophagy-mediated longevity is modulated by lipoprotein biogenesis
- (2015) Nicole E. Seah et al. Autophagy
- Neuronal CRTC-1 Governs Systemic Mitochondrial Metabolism and Lifespan via a Catecholamine Signal
- (2015) Kristopher Burkewitz et al. CELL
- Glial Lipid Droplets and ROS Induced by Mitochondrial Defects Promote Neurodegeneration
- (2015) Lucy Liu et al. CELL
- SKN-1/Nrf, stress responses, and aging in Caenorhabditis elegans
- (2015) T. Keith Blackwell et al. FREE RADICAL BIOLOGY AND MEDICINE
- Membrane lipid rafts and neurobiology: age-related changes in membrane lipids and loss of neuronal function
- (2015) Junji Egawa et al. JOURNAL OF PHYSIOLOGY-LONDON
- Metabolic functions of FABPs—mechanisms and therapeutic implications
- (2015) Gökhan S. Hotamisligil et al. Nature Reviews Endocrinology
- Lysosomal signaling molecules regulate longevity in Caenorhabditis elegans
- (2015) A. Folick et al. SCIENCE
- Vibrational spectroscopic imaging of living systems: An emerging platform for biology and medicine
- (2015) J.-X. Cheng et al. SCIENCE
- Lipid-mediated regulation of SKN-1/Nrf in response to germ cell absence
- (2015) Michael J Steinbaugh et al. eLife
- Exome sequencing of three cases of familial exceptional longevity
- (2014) Timothy P. Cash et al. AGING CELL
- Diacylglycerol lipaseregulates lifespan and oxidative stress response by inversely modulating TOR signaling inDrosophilaandC. elegans
- (2014) Yen-Hung Lin et al. AGING CELL
- TRPV1 Pain Receptors Regulate Longevity and Metabolism by Neuropeptide Signaling
- (2014) Céline E. Riera et al. CELL
- Nuclear Receptors, RXR, and the Big Bang
- (2014) Ronald M. Evans et al. CELL
- Live-cell imaging of alkyne-tagged small biomolecules by stimulated Raman scattering
- (2014) Lu Wei et al. NATURE METHODS
- Metformin—mode of action and clinical implications for diabetes and cancer
- (2014) Ida Pernicova et al. Nature Reviews Endocrinology
- Steroid hormone signalling links reproduction to lifespan in dietary-restricted Caenorhabditis elegans
- (2014) Manjunatha Thondamal et al. Nature Communications
- Germline Signals Deploy NHR-49 to Modulate Fatty-Acid β-Oxidation and Desaturation in Somatic Tissues of C. elegans
- (2014) Ramesh Ratnappan et al. PLoS Genetics
- Lipidomics of familial longevity
- (2013) Vanessa Gonzalez-Covarrubias et al. AGING CELL
- Glucagon-Like Peptide-1: Glucose Homeostasis and Beyond
- (2013) Young Min Cho et al. Annual Review of Physiology
- A Genetic Program Promotes C. elegans Longevity at Cold Temperatures via a Thermosensitive TRP Channel
- (2013) Rui Xiao et al. CELL
- The NHR-8 Nuclear Receptor Regulates Cholesterol and Bile Acid Homeostasis in C. elegans
- (2013) Daniel B. Magner et al. Cell Metabolism
- Adenosine Nucleotide Biosynthesis and AMPK Regulate Adult Life Span and Mediate the Longevity Benefit of Caloric Restriction in Flies
- (2013) Drew Stenesen et al. Cell Metabolism
- Direct and Indirect Gene Regulation by a Life-Extending FOXO Protein in C. elegans: Roles for GATA Factors and Lipid Gene Regulators
- (2013) Peichuan Zhang et al. Cell Metabolism
- MXL-3 and HLH-30 transcriptionally link lipolysis and autophagy to nutrient availability
- (2013) Eyleen J. O’Rourke et al. NATURE CELL BIOLOGY
- Bile acid receptors as targets for drug development
- (2013) Frank G. Schaap et al. Nature Reviews Gastroenterology & Hepatology
- Functional Loss of Two Ceramide Synthases Elicits Autophagy-Dependent Lifespan Extension in C. elegans
- (2013) Mai-Britt Mosbech et al. PLoS One
- What are lipoproteins doing in the brain?
- (2013) Hong Wang et al. TRENDS IN ENDOCRINOLOGY AND METABOLISM
- The TFEB orthologue HLH-30 regulates autophagy and modulates longevity in Caenorhabditis elegans
- (2013) Louis R. Lapierre et al. Nature Communications
- Dietary Restriction Induced Longevity Is Mediated by Nuclear Receptor NHR-62 in Caenorhabditis elegans
- (2013) Bree N. Heestand et al. PLoS Genetics
- The extreme longevity ofArctica islandicais associated with increased peroxidation resistance in mitochondrial membranes
- (2012) Daniel Munro et al. AGING CELL
- The mystery of C. elegans aging: An emerging role for fat
- (2012) Daniel Ackerman et al. BIOESSAYS
- Pten Positively Regulates Brown Adipose Function, Energy Expenditure, and Longevity
- (2012) Ana Ortega-Molina et al. Cell Metabolism
- The lifespan of Korean eunuchs
- (2012) Kyung-Jin Min et al. CURRENT BIOLOGY
- A lysosome-to-nucleus signalling mechanism senses and regulates the lysosome via mTOR and TFEB
- (2012) Carmine Settembre et al. EMBO JOURNAL
- Serum ceramides increase the risk of Alzheimer disease: The Women's Health and Aging Study II
- (2012) M. M. Mielke et al. NEUROLOGY
- Lessons from C. elegans: signaling pathways for longevity
- (2012) Louis R. Lapierre et al. TRENDS IN ENDOCRINOLOGY AND METABOLISM
- Coordinate Regulation of Lipid Metabolism by Novel Nuclear Receptor Partnerships
- (2012) Pranali P. Pathare et al. PLoS Genetics
- Insulin Signaling Regulates Fatty Acid Catabolism at the Level of CoA Activation
- (2012) Xiaojun Xu et al. PLoS Genetics
- Akt Stimulates Hepatic SREBP1c and Lipogenesis through Parallel mTORC1-Dependent and Independent Pathways
- (2011) Jessica L. Yecies et al. Cell Metabolism
- Autophagy and Lipid Metabolism Coordinately Modulate Life Span in Germline-less C. elegans
- (2011) Louis R. Lapierre et al. CURRENT BIOLOGY
- Novel Functions of Lipid-binding Protein 5 inCaenorhabditis elegansFat Metabolism
- (2011) Mo Xu et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- N-acylethanolamine signalling mediates the effect of diet on lifespan in Caenorhabditis elegans
- (2011) Mark Lucanic et al. NATURE
- Fatty Acid Desaturation Links Germ Cell Loss to Longevity Through NHR-80/HNF4 in C. elegans
- (2011) Jérôme Goudeau et al. PLOS BIOLOGY
- A Deficiency of Ceramide Biosynthesis Causes Cerebellar Purkinje Cell Neurodegeneration and Lipofuscin Accumulation
- (2011) Lihong Zhao et al. PLoS Genetics
- HRAS1 and LASS1 with APOE are associated with human longevity and healthy aging
- (2010) S. Michal Jazwinski et al. AGING CELL
- Fatty acid amide signaling molecules
- (2010) Cyrine Ezzili et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Role of Drosophila alkaline ceramidase (Dacer) in Drosophila development and longevity
- (2010) Qiong Yang et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Mammalian Target of Rapamycin Complex 1 Suppresses Lipolysis, Stimulates Lipogenesis, and Promotes Fat Storage
- (2010) P. Chakrabarti et al. DIABETES
- mTORC1 Inhibition via Rapamycin Promotes Triacylglycerol Lipolysis and Release of Free Fatty Acids in 3T3-L1 Adipocytes
- (2010) Ghada A. Soliman et al. LIPIDS
- Functional modularity of nuclear hormone receptors in a Caenorhabditis elegans metabolic gene regulatory network
- (2010) H Efsun Arda et al. Molecular Systems Biology
- mTORC1 controls fasting-induced ketogenesis and its modulation by ageing
- (2010) Shomit Sengupta et al. NATURE
- Bifurcation of insulin signaling pathway in rat liver: mTORC1 required for stimulation of lipogenesis, but not inhibition of gluconeogenesis
- (2010) Shijie Li et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Insulin/IGF-1 signaling mutants reprogram ER stress response regulators to promote longevity
- (2010) S. Henis-Korenblit et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Increase in sphingolipid catabolic enzyme activity during aging
- (2009) Santosh J Sacket et al. ACTA PHARMACOLOGICA SINICA
- Meta-analysis of age-related gene expression profiles identifies common signatures of aging
- (2009) João Pedro de Magalhães et al. BIOINFORMATICS
- Drosophila HNF4 Regulates Lipid Mobilization and β-Oxidation
- (2009) Laura Palanker et al. Cell Metabolism
- C. elegans Major Fats Are Stored in Vesicles Distinct from Lysosome-Related Organelles
- (2009) Eyleen J. O'Rourke et al. Cell Metabolism
- GPR119 Is Essential for Oleoylethanolamide-Induced Glucagon-Like Peptide-1 Secretion From the Intestinal Enteroendocrine L-Cell
- (2009) L. M. Lauffer et al. DIABETES
- Bile acids: regulation of synthesis
- (2009) John Y. L. Chiang JOURNAL OF LIPID RESEARCH
- Protection of C. elegans from Anoxia by HYL-2 Ceramide Synthase
- (2009) V. Menuz et al. SCIENCE
- Control of Metabolic Homeostasis by Stress Signaling Is Mediated by the Lipocalin NLaz
- (2009) Julie Hull-Thompson et al. PLoS Genetics
- Apolipoprotein D is involved in the mechanisms regulating protection from oxidative stress
- (2008) Maria D. Ganfornina et al. AGING CELL
- A 13C Isotope Labeling Strategy Reveals the Influence of Insulin Signaling on Lipogenesis in C. elegans
- (2008) Carissa L. Perez et al. Cell Metabolism
- TRPV1-null mice are protected from diet-induced obesity
- (2008) Arianne L. Motter et al. FEBS LETTERS
- Human ApoD, an apolipoprotein up-regulated in neurodegenerative diseases, extends lifespan and increases stress resistance in Drosophila
- (2008) J. Muffat et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Drosophila germ-line modulation of insulin signaling and lifespan
- (2008) T. Flatt et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Fat Metabolism Links Germline Stem Cells and Longevity in C. elegans
- (2008) M. C. Wang et al. SCIENCE
- A TRPV Channel Modulates C. elegans Neurosecretion, Larval Starvation Survival, and Adult Lifespan
- (2008) Brian H. Lee et al. PLoS Genetics
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now