Dynamics and functions of lipid droplets

An Asymmetry in Monolayer Tension Regulates Lipid Droplet Budding Direction

(2018) Aymeric Chorlay et al.   BIOPHYSICAL JOURNAL

The Inner Nuclear Membrane Is a Metabolically Active Territory that Generates Nuclear Lipid Droplets

(2018) Anete Romanauska et al.   CELL

Mitochondria Bound to Lipid Droplets Have Unique Bioenergetics, Composition, and Dynamics that Support Lipid Droplet Expansion

(2018) Ilan Y. Benador et al.   Cell Metabolism

Architecture of Lipid Droplets in Endoplasmic Reticulum Is Determined by Phospholipid Intrinsic Curvature

(2018) Vineet Choudhary et al.   CURRENT BIOLOGY

Converging cellular themes for the hereditary spastic paraplegias

(2018) Craig Blackstone   CURRENT OPINION IN NEUROBIOLOGY

A Proximity Labeling Strategy Provides Insights into the Composition and Dynamics of Lipid Droplet Proteomes

(2018) Kirill Bersuker et al.   DEVELOPMENTAL CELL

PCYT1A Regulates Phosphatidylcholine Homeostasis from the Inner Nuclear Membrane in Response to Membrane Stored Curvature Elastic Stress

(2018) Afreen Haider et al.   DEVELOPMENTAL CELL

Mechanism and Determinants of Amphipathic Helix-Containing Protein Targeting to Lipid Droplets

(2018) Coline Prévost et al.   DEVELOPMENTAL CELL

SNX14 mutations affect endoplasmic reticulum-associated neutral lipid metabolism in autosomal recessive spinocerebellar ataxia 20

(2018) Dale Bryant et al.   HUMAN MOLECULAR GENETICS

Rab18 promotes lipid droplet (LD) growth by tethering the ER to LDs through SNARE and NRZ interactions

(2018) Dijin Xu et al.   JOURNAL OF CELL BIOLOGY

Rab18 is not necessary for lipid droplet biogenesis or turnover in human mammary carcinoma cells

(2018) Christina B. K. Jayson et al.   MOLECULAR BIOLOGY OF THE CELL

The coming of age of chaperone-mediated autophagy

(2018) Susmita Kaushik et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Systematic mapping of contact sites reveals tethers and a function for the peroxisome-mitochondria contact

(2018) Nadav Shai et al.   Nature Communications

A giant amphipathic helix from a perilipin that is adapted for coating lipid droplets

(2018) Alenka Čopič et al.   Nature Communications

Proteomic analysis of monolayer-integrated proteins on lipid droplets identifies amphipathic interfacial α-helical membrane anchors

(2018) Camille I. Pataki et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Human SEIPIN Binds Anionic Phospholipids

(2018) Renhong Yan et al.   DEVELOPMENTAL CELL

Cryo–electron microscopy structure of the lipid droplet–formation protein seipin

(2018) Xuewu Sui et al.   JOURNAL OF CELL BIOLOGY

Identification of seipin-linked factors that act as determinants of a lipid droplet subpopulation

(2017) Michal Eisenberg-Bord et al.   JOURNAL OF CELL BIOLOGY

Pet10p is a yeast perilipin that stabilizes lipid droplets and promotes their assembly

(2017) Qiang Gao et al.   JOURNAL OF CELL BIOLOGY

Regulation of lipid droplets by metabolically controlled Ldo isoforms

(2017) Vitor Teixeira et al.   JOURNAL OF CELL BIOLOGY

HDAC6-mediated acetylation of lipid droplet–binding protein CIDEC regulates fat-induced lipid storage

(2017) Hui Qian et al.   JOURNAL OF CLINICAL INVESTIGATION

Lipid disequilibrium disrupts ER proteostasis by impairing ERAD substrate glycan trimming and dislocation

(2017) Milton To et al.   MOLECULAR BIOLOGY OF THE CELL

Activation of the Unfolded Protein Response by Lipid Bilayer Stress

(2017) Kristina Halbleib et al.   MOLECULAR CELL

Applying systems-level spectral imaging and analysis to reveal the organelle interactome

(2017) Alex M. Valm et al.   NATURE

Cytosolic lipolysis and lipophagy: two sides of the same coin

(2017) Rudolf Zechner et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Endoplasmic Reticulum–Associated Degradation and Lipid Homeostasis

(2016) Julian Stevenson et al.   Annual Review of Nutrition

AMPK-dependent phosphorylation of lipid droplet protein PLIN2 triggers its degradation by CMA

(2016) Susmita Kaushik et al.   Autophagy

The physics of lipid droplet nucleation, growth and budding

(2016) Abdou Rachid Thiam et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

The Secreted Enzyme PM20D1 Regulates Lipidated Amino Acid Uncouplers of Mitochondria

(2016) Jonathan Z. Long et al.   CELL

COP-coated vesicles

(2016) Natalia Gomez-Navarro et al.   CURRENT BIOLOGY

Spatial control of lipid droplet proteins by the ERAD ubiquitin ligase Doa10

(2016) Annamaria Ruggiano et al.   EMBO JOURNAL

Seipin regulates ER–lipid droplet contacts and cargo delivery

(2016) Veijo T Salo et al.   EMBO JOURNAL

Conserved Amphipathic Helices Mediate Lipid Droplet Targeting of Perilipins 1–3

(2016) Emily R. Rowe et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

PML isoform II plays a critical role in nuclear lipid droplet formation

(2016) Yuki Ohsaki et al.   JOURNAL OF CELL BIOLOGY

Lipid droplet–mediated ER homeostasis regulates autophagy and cell survival during starvation

(2016) Ariadna P. Velázquez et al.   JOURNAL OF CELL BIOLOGY

A family of membrane-shaping proteins at ER subdomains regulates pre-peroxisomal vesicle biogenesis

(2016) Amit S. Joshi et al.   JOURNAL OF CELL BIOLOGY

Mature lipid droplets are accessible to ER luminal proteins

(2016) Shirish Mishra et al.   JOURNAL OF CELL SCIENCE

Peroxin-dependent targeting of a lipid-droplet-destined membrane protein to ER subdomains

(2016) Bianca Schrul et al.   NATURE CELL BIOLOGY

Lipid somersaults: Uncovering the mechanisms of protein-mediated lipid flipping

(2016) Thomas Günther Pomorski et al.   PROGRESS IN LIPID RESEARCH

Nuclear Perilipin 5 integrates lipid droplet lipolysis with PGC-1α/SIRT1-dependent transcriptional regulation of mitochondrial function

(2016) Violeta I. Gallardo-Montejano et al.   Nature Communications

SEIPIN Regulates Lipid Droplet Expansion and Adipocyte Development by Modulating the Activity of Glycerol-3-phosphate Acyltransferase

(2016) Martin Pagac et al.   Cell Reports

Regulation of Hepatic Triacylglycerol Metabolism by CGI-58 Does Not Require ATGL Co-activation

(2016) Caleb C. Lord et al.   Cell Reports

Autophagy and Lipid Droplets in the Liver

(2015) Nuria Martinez-Lopez et al.   Annual Review of Nutrition

Seipin is involved in the regulation of phosphatidic acid metabolism at a subdomain of the nuclear envelope in yeast

(2015) Heimo Wolinski et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Palmitoyl-carnitine increases RyR2 oxidation and sarcoplasmic reticulum Ca2+ leak in cardiomyocytes: Role of adenine nucleotide translocase

(2015) J. Roussel et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Antioxidant Role for Lipid Droplets in a Stem Cell Niche of Drosophila

(2015) Andrew P. Bailey et al.   CELL

Glial Lipid Droplets and ROS Induced by Mitochondrial Defects Promote Neurodegeneration

(2015) Lucy Liu et al.   CELL

Lipid Droplets Are Essential for Efficient Clearance of Cytosolic Inclusion Bodies

(2015) Ofer Moldavski et al.   DEVELOPMENTAL CELL

Role for Lipid Droplet Biogenesis and Microlipophagy in Adaptation to Lipid Imbalance in Yeast

(2015) Jason D. Vevea et al.   DEVELOPMENTAL CELL

Fatty Acid Trafficking in Starved Cells: Regulation by Lipid Droplet Lipolysis, Autophagy, and Mitochondrial Fusion Dynamics

(2015) Angelika S. Rambold et al.   DEVELOPMENTAL CELL

The small GTPase Rab7 as a central regulator of hepatocellular lipophagy

(2015) Barbara Schroeder et al.   HEPATOLOGY

Postnatal Deletion of Fat Storage-inducing Transmembrane Protein 2 (FIT2/FITM2) Causes Lethal Enteropathy

(2015) Vera J. Goh et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mdm1/Snx13 is a novel ER–endolysosomal interorganelle tethering protein

(2015) W. Mike Henne et al.   JOURNAL OF CELL BIOLOGY

The seipin complex Fld1/Ldb16 stabilizes ER–lipid droplet contact sites

(2015) Alexandra Grippa et al.   JOURNAL OF CELL BIOLOGY

A conserved family of proteins facilitates nascent lipid droplet budding from the ER

(2015) Vineet Choudhary et al.   JOURNAL OF CELL BIOLOGY

Seipin performs dissectible functions in promoting lipid droplet biogenesis and regulating droplet morphology

(2015) Bethany R. Cartwright et al.   MOLECULAR BIOLOGY OF THE CELL

Nuclear-localized CTP:phosphocholine cytidylyltransferase α regulates phosphatidylcholine synthesis required for lipid droplet biogenesis

(2015) Adam J. Aitchison et al.   MOLECULAR BIOLOGY OF THE CELL

Transcriptional control of autophagy–lysosome function drives pancreatic cancer metabolism

(2015) Rushika M. Perera et al.   NATURE

Nutrient-sensing mechanisms and pathways

(2015) Alejo Efeyan et al.   NATURE

Degradation of lipid droplet-associated proteins by chaperone-mediated autophagy facilitates lipolysis

(2015) Susmita Kaushik et al.   NATURE CELL BIOLOGY

Acylcarnitines—old actors auditioning for new roles in metabolic physiology

(2015) Colin S. McCoin et al.   Nature Reviews Endocrinology

Peroxisome extensions deliver theArabidopsisSDP1 lipase to oil bodies

(2015) Nelcy Thazar-Poulot et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

AMPK activation promotes lipid droplet dispersion on detyrosinated microtubules to increase mitochondrial fatty acid oxidation

(2015) Albert Herms et al.   Nature Communications

The brown adipocyte protein CIDEA promotes lipid droplet fusion via a phosphatidic acid-binding amphipathic helix

(2015) David Barneda et al.   eLife

Deficient Chaperone-Mediated Autophagy in Liver Leads to Metabolic Dysregulation

(2014) Jaime L. Schneider et al.   Cell Metabolism

Rab8a-AS160-MSS4 Regulatory Circuit Controls Lipid Droplet Fusion and Growth

(2014) Lizhen Wu et al.   DEVELOPMENTAL CELL

Fat Storage-inducing Transmembrane Protein 2 Is Required for Normal Fat Storage in Adipose Tissue

(2014) Diego A. Miranda et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cardiomyocyte-specific Loss of Diacylglycerol Acyltransferase 1 (DGAT1) Reproduces the Abnormalities in Lipids Found in Severe Heart Failure

(2014) Li Liu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Bridging the gap: Membrane contact sites in signaling, metabolism, and organelle dynamics

(2014) William A. Prinz   JOURNAL OF CELL BIOLOGY

A sterol-enriched vacuolar microdomain mediates stationary phase lipophagy in budding yeast

(2014) Chao-Wen Wang et al.   JOURNAL OF CELL BIOLOGY

ER-associated degradation: Protein quality control and beyond

(2014) Annamaria Ruggiano et al.   JOURNAL OF CELL BIOLOGY

Control of lipid droplet size in budding yeast requires the collaboration between Fld1 and Ldb16

(2014) C.-W. Wang et al.   JOURNAL OF CELL SCIENCE

High confidence proteomic analysis of yeast LDs identifies additional droplet proteins and reveals connections to dolichol synthesis and sterol acetylation

(2014) Erin Currie et al.   JOURNAL OF LIPID RESEARCH

Cargo recognition and trafficking in selective autophagy

(2014) Alexandra Stolz et al.   NATURE CELL BIOLOGY

Exome-wide association study identifies a TM6SF2 variant that confers susceptibility to nonalcoholic fatty liver disease

(2014) Julia Kozlitina et al.   NATURE GENETICS

TM6SF2 is a regulator of liver fat metabolism influencing triglyceride secretion and hepatic lipid droplet content

(2014) H. Mahdessian et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

An ER Protein Functionally Couples Neutral Lipid Metabolism on Lipid Droplets to Membrane Lipid Synthesis in the ER

(2014) Daniel F. Markgraf et al.   Cell Reports

Arf1/COPI machinery acts directly on lipid droplets and enables their connection to the ER for protein targeting

(2014) Florian Wilfling et al.   eLife

FSP27 and PLIN1 interaction promotes the formation of large lipid droplets in human adipocytes

(2013) Tan Hooi Min Grahn et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Composition, structure and properties of POPC–triolein mixtures. Evidence of triglyceride domains in phospholipid bilayers

(2013) Lars Duelund et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Cell-to-Cell Heterogeneity in Lipid Droplets Suggests a Mechanism to Reduce Lipotoxicity

(2013) Albert Herms et al.   CURRENT BIOLOGY

Triacylglycerol Synthesis Enzymes Mediate Lipid Droplet Growth by Relocalizing from the ER to Lipid Droplets

(2013) Florian Wilfling et al.   DEVELOPMENTAL CELL

Balancing the fat: lipid droplets and human disease

(2013) Natalie Krahmer et al.   EMBO Molecular Medicine

Acyl-CoA synthetase 3 promotes lipid droplet biogenesis in ER microdomains

(2013) Adam Kassan et al.   JOURNAL OF CELL BIOLOGY

Direct imaging reveals stable, micrometer-scale lipid domains that segregate proteins in live cells

(2013) Alexandre Toulmay et al.   JOURNAL OF CELL BIOLOGY

Protein Correlation Profiles Identify Lipid Droplet Proteins with High Confidence

(2013) Natalie Krahmer et al.   MOLECULAR & CELLULAR PROTEOMICS

The biophysics and cell biology of lipid droplets

(2013) Abdou Rachid Thiam et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Monoubiquitination of Ancient Ubiquitous Protein 1 Promotes Lipid Droplet Clustering

(2013) Daniel Lohmann et al.   PLoS One

COPI buds 60-nm lipid droplets from reconstituted water-phospholipid-triacylglyceride interfaces, suggesting a tension clamp function

(2013) A. R. Thiam et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Spatial regulation of UBXD8 and p97/VCP controls ATGL-mediated lipid droplet turnover

(2013) James A. Olzmann et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Membrane lipid saturation activates endoplasmic reticulum unfolded protein response transducers through their transmembrane domains

(2013) R. Volmer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Conserved Role for Atlastin GTPases in Regulating Lipid Droplet Size

(2013) Robin W. Klemm et al.   Cell Reports

Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death

(2012) Scott J. Dixon et al.   CELL

Remodeling of Lipid Droplets during Lipolysis and Growth in Adipocytes

(2012) Margret Paar et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The FATP1–DGAT2 complex facilitates lipid droplet expansion at the ER–lipid droplet interface

(2012) Ningyi Xu et al.   JOURNAL OF CELL BIOLOGY

Active involvement of micro-lipid droplets and lipid-droplet-associated proteins in hormone-stimulated lipolysis in adipocytes

(2012) T. Hashimoto et al.   JOURNAL OF CELL SCIENCE

Diacylglycerol acyl transferase 1 overexpression detoxifies cardiac lipids in PPARγ transgenic mice

(2012) Li Liu et al.   JOURNAL OF LIPID RESEARCH

Postlipolytic insulin-dependent remodeling of micro lipid droplets in adipocytes

(2012) Nicholas Ariotti et al.   MOLECULAR BIOLOGY OF THE CELL

Derlin-1 and UBXD8 are engaged in dislocation and degradation of lipidated ApoB-100 at lipid droplets

(2012) Michitaka Suzuki et al.   MOLECULAR BIOLOGY OF THE CELL

Ancient ubiquitous protein-1 mediates sterol-induced ubiquitination of 3-hydroxy-3-methylglutaryl CoA reductase in lipid droplet–associated endoplasmic reticulum membranes

(2012) Youngah Jo et al.   MOLECULAR BIOLOGY OF THE CELL

Phosphatidylcholine Synthesis for Lipid Droplet Expansion Is Mediated by Localized Activation of CTP:Phosphocholine Cytidylyltransferase

(2011) Natalie Krahmer et al.   Cell Metabolism

Pancreatic cancers require autophagy for tumor growth

(2011) S. Yang et al.   GENES & DEVELOPMENT

Dual Role of Ancient Ubiquitous Protein 1 (AUP1) in Lipid Droplet Accumulation and Endoplasmic Reticulum (ER) Protein Quality Control

(2011) Elizabeth J. Klemm et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Lipid Droplet Formation Is Dispensable for Endoplasmic Reticulum-associated Degradation

(2011) James A. Olzmann et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Fsp27 promotes lipid droplet growth by lipid exchange and transfer at lipid droplet contact sites

(2011) Jingyi Gong et al.   JOURNAL OF CELL BIOLOGY

The yeast lipin orthologue Pah1p is important for biogenesis of lipid droplets

(2011) Oludotun Adeyo et al.   JOURNAL OF CELL BIOLOGY

Lipid droplets are functionally connected to the endoplasmic reticulum in Saccharomyces cerevisiae

(2011) N. Jacquier et al.   JOURNAL OF CELL SCIENCE

The role of lipid droplets in metabolic disease in rodents and humans

(2011) Andrew S. Greenberg et al.   JOURNAL OF CLINICAL INVESTIGATION

Perilipin 5, a lipid droplet-associated protein, provides physical and metabolic linkage to mitochondria

(2011) Hong Wang et al.   JOURNAL OF LIPID RESEARCH

Membrane aberrancy and unfolded proteins activate the endoplasmic reticulum stress sensor Ire1 in different ways

(2011) Thanyarat Promlek et al.   MOLECULAR BIOLOGY OF THE CELL

Aberrant lipid metabolism disrupts calcium homeostasis causing liver endoplasmic reticulum stress in obesity

(2011) Suneng Fu et al.   NATURE

FSP27 Promotes Lipid Droplet Clustering and Then Fusion to Regulate Triglyceride Accumulation

(2011) Srikarthika Jambunathan et al.   PLoS One

Direct binding of triglyceride to fat storage-inducing transmembrane proteins 1 and 2 is important for lipid droplet formation

(2011) D. A. Gross et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

mTORC1 Senses Lysosomal Amino Acids Through an Inside-Out Mechanism That Requires the Vacuolar H+-ATPase

(2011) R. Zoncu et al.   SCIENCE

The Unfolded Protein Response: From Stress Pathway to Homeostatic Regulation

(2011) P. Walter et al.   SCIENCE

Seipin Is a Discrete Homooligomer

(2010) Derk Binns et al.   BIOCHEMISTRY

Spartin activates atrophin-1-interacting protein 4 (AIP4) E3 ubiquitin ligase and promotes ubiquitination of adipophilin on lipid droplets

(2010) Christopher Hooper et al.   BMC BIOLOGY

Interactions of Perilipin-5 (Plin5) with Adipose Triglyceride Lipase

(2010) James G. Granneman et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Coordination of Storage Lipid Synthesis and Membrane Biogenesis

(2010) Maria L. Gaspar et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Ancient Ubiquitous Protein 1 (AUP1) Localizes to Lipid Droplets and Binds the E2 Ubiquitin Conjugase G2 (Ube2g2) via Its G2 Binding Region

(2010) Johanna Spandl et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Sterol-induced Dislocation of 3-Hydroxy-3-methylglutaryl Coenzyme A Reductase from Endoplasmic Reticulum Membranes into the Cytosol through a Subcellular Compartment Resembling Lipid Droplets

(2010) Isamu Z. Hartman et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

PPARγ-induced cardiolipotoxicity in mice is ameliorated by PPARα deficiency despite increases in fatty acid oxidation

(2010) Ni-Huiping Son et al.   JOURNAL OF CLINICAL INVESTIGATION

Triglyceride Blisters in Lipid Bilayers: Implications for Lipid Droplet Biogenesis and the Mobile Lipid Signal in Cancer Cell Membranes

(2010) Himanshu Khandelia et al.   PLoS One

Neutral lipid storage disease: genetic disorders caused by mutations in adipose triglyceride lipase/PNPLA2 or CGI-58/ABHD5

(2009) Martina Schweiger et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Endogenous spartin (SPG20) is recruited to endosomes and lipid droplets and interacts with the ubiquitin E3 ligases AIP4 and AIP5

(2009) Thomas L. Edwards et al.   BIOCHEMICAL JOURNAL

Lipid Droplets Finally Get a Little R-E-S-P-E-C-T

(2009) Robert V. Farese et al.   CELL

Partial lipodystrophy and insulin resistant diabetes in a patient with a homozygous nonsense mutation inCIDEC

(2009) Oscar Rubio-Cabezas et al.   EMBO Molecular Medicine

DGAT1 Expression Increases Heart Triglyceride Content but Ameliorates Lipotoxicity

(2009) Li Liu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Good Fat, Essential Cellular Requirements for Triacylglycerol Synthesis to Maintain Membrane Homeostasis in Yeast

(2009) Julia Petschnigg et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Diacylglycerol Enrichment of Endoplasmic Reticulum or Lipid Droplets Recruits Perilipin 3/TIP47 during Lipid Storage and Mobilization

(2009) James R. Skinner et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A role for ubiquitin ligases and Spartin/SPG20 in lipid droplet turnover

(2009) Scott W. Eastman et al.   JOURNAL OF CELL BIOLOGY

TIP47 functions in the biogenesis of lipid droplets

(2009) Anna V. Bulankina et al.   JOURNAL OF CELL BIOLOGY

The antiviral protein, viperin, localizes to lipid droplets via its N-terminal amphipathic  -helix

(2009) E. R. Hinson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hydrophobic and Basic Domains Target Proteins to Lipid Droplets

(2009) Mercedes Ingelmo-Torres et al.   TRAFFIC

Lipodystrophy Syndromes

(2008) Pedro Herranz et al.   DERMATOLOGIC CLINICS

UPR Pathways Combine to Prevent Hepatic Steatosis Caused by ER Stress-Mediated Suppression of Transcriptional Master Regulators

(2008) D. Thomas Rutkowski et al.   DEVELOPMENTAL CELL

Fld1p, a functional homologue of human seipin, regulates the size of lipid droplets in yeast

(2008) Weihua Fei et al.   JOURNAL OF CELL BIOLOGY

Lipid droplets are arrested in the ER membrane by tight binding of lipidated apolipoprotein B-100

(2008) Y. Ohsaki et al.   JOURNAL OF CELL SCIENCE

Thematic Review Series: Glycerolipids.DGAT enzymes and triacylglycerol biosynthesis

(2008) Chi-Liang Eric Yen et al.   JOURNAL OF LIPID RESEARCH

Genetic variation in PNPLA3 confers susceptibility to nonalcoholic fatty liver disease

(2008) Stefano Romeo et al.   NATURE GENETICS