Neuroinflammation in neurological disorders: pharmacotherapeutic targets from bench to bedside
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Title
Neuroinflammation in neurological disorders: pharmacotherapeutic targets from bench to bedside
Authors
Keywords
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Journal
METABOLIC BRAIN DISEASE
Volume 36, Issue 7, Pages 1591-1626
Publisher
Springer Science and Business Media LLC
Online
2021-08-13
DOI
10.1007/s11011-021-00806-4
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Note: Only part of the references are listed.- Anticonvulsive effects of edaravone on penicillin‐induced focal onset seizure model in the conscious rats
- (2021) Semiha Kurt et al. FUNDAMENTAL & CLINICAL PHARMACOLOGY
- Neuroprotective potential of cinnamon and its metabolites in Parkinson's disease: Mechanistic insights, limitations, and novel therapeutic opportunities
- (2021) Efthalia Angelopoulou et al. JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY
- New approaches to symptomatic treatments for Alzheimer’s disease
- (2021) Jeffrey Cummings Molecular Neurodegeneration
- Etanercept rescues cognitive deficits, depression-like symptoms, and spike-wave discharge incidence in WAG/Rij rat model of absence epilepsy
- (2021) Ayşe Karson et al. EPILEPSY & BEHAVIOR
- Targeting Microglia-Synapse Interactions in Alzheimer’s Disease
- (2021) Gaia Piccioni et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Sex-Independent Cognition Improvement in Response to Kaempferol in the Model of Sporadic Alzheimer’s Disease
- (2021) Parvin Babaei et al. NEUROCHEMICAL RESEARCH
- Linalool Alleviates Aβ42-Induced Neurodegeneration via Suppressing ROS Production and Inflammation in Fly and Rat Models of Alzheimer’s Disease
- (2021) Chunyu Yuan et al. Oxidative Medicine and Cellular Longevity
- Neurodegenerative Disease and the NLRP3 Inflammasome
- (2021) Jonathan A. Holbrook et al. Frontiers in Pharmacology
- Alpha-Synuclein: Mechanisms of Release and Pathology Progression in Synucleinopathies
- (2021) Inês C. Brás et al. Cells
- Neuroprotective effect of Betalain against AlCl3-induced Alzheimer's disease in Sprague Dawley Rats via putative modulation of oxidative stress and nuclear factor kappa B (NF-κB) signaling pathway
- (2021) Di Shunan et al. BIOMEDICINE & PHARMACOTHERAPY
- Neuroprotective effects of dexpanthenol on streptozotocin-induced neuronal damage in rats
- (2021) Mumin Alper Erdogan et al. DRUG AND CHEMICAL TOXICOLOGY
- The cell biology of Parkinson’s disease
- (2021) Nikhil Panicker et al. JOURNAL OF CELL BIOLOGY
- HMGB1/RAGE/TLR4 axis and glutamate as novel targets for PCSK9 inhibitor in high fat cholesterol diet induced cognitive impairment and amyloidosis
- (2021) Sally A. Abuelezz et al. LIFE SCIENCES
- Neuroinflammatory Mechanisms of Mitochondrial Dysfunction and Neurodegeneration in Glaucoma
- (2021) Joao N. Duarte Journal of Ophthalmology
- Camptothecin Regulates Microglia Polarization and Exerts Neuroprotective Effects via Activating AKT/Nrf2/HO-1 and Inhibiting NF-κB Pathways In Vivo and In Vitro
- (2021) Dewei He et al. Frontiers in Immunology
- Role of curcumin and its nanoformulations in neurotherapeutics: A comprehensive review
- (2020) Mukesh Mandal et al. JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY
- Decreased expression of Rev-Erbα in the epileptic foci of temporal lobe epilepsy and activation of Rev-Erbα have anti-inflammatory and neuroprotective effects in the pilocarpine model
- (2020) Jiong Yue et al. Journal of Neuroinflammation
- In search of an anti-inflammatory drug for Alzheimer disease
- (2020) Erika Gyengesi et al. Nature Reviews Neurology
- Role of flavonoids in neurodegenerative diseases: Limitations and future perspectives
- (2020) Gagandeep Maan et al. CURRENT TOPICS IN MEDICINAL CHEMISTRY
- Curcumin loaded nanoparticles reversed monocrotophos induced motor impairment and memory deficit: Role of oxidative stress and intracellular calcium level
- (2020) Mukesh Mandal et al. JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY
- Inverse Agonism of Cannabinoid Receptor Type 2 Confers Anti-inflammatory and Neuroprotective Effects Following Status Epileptics
- (2020) Ying Yu et al. MOLECULAR NEUROBIOLOGY
- Ten Unsolved Questions About Neuroinflammation in Parkinson's Disease
- (2020) Etienne C. Hirsch et al. MOVEMENT DISORDERS
- Author response: INTREPAD: A randomized trial of naproxen to slow progress of presymptomatic Alzheimer disease
- (2020) John Breitner et al. NEUROLOGY
- Protective effect of Indole-3-carbinol, an NF-κB inhibitor in experimental paradigm of Parkinson’s disease: In silico and in vivo studies
- (2020) Neerja Saini et al. BRAIN BEHAVIOR AND IMMUNITY
- Methylprednisolone pulse therapy in 31 patients with refractory epilepsy: A single-center retrospective analysis
- (2020) Tomokazu Kimizu et al. EPILEPSY & BEHAVIOR
- Effect of hesperidin on fluoride‐induced neurobehavioral and biochemical changes in rats
- (2020) Pawan Jaiswal et al. JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY
- Hyperoside alleviates epilepsy-induced neuronal damage by enhancing antioxidant levels and reducing autophagy
- (2020) Jianwen Cao et al. JOURNAL OF ETHNOPHARMACOLOGY
- Ibuprofen Exerts Antiepileptic and Neuroprotective Effects in the Rat Model of Pentylenetetrazol-Induced Epilepsy via the COX-2/NLRP3/IL-18 Pathway
- (2020) Rui Liu et al. NEUROCHEMICAL RESEARCH
- IL-6 Receptor Blockade by Tocilizumab Has Anti-absence and Anti-epileptogenic Effects in the WAG/Rij Rat Model of Absence Epilepsy
- (2020) Antonio Leo et al. Neurotherapeutics
- Drug Resistance in Epilepsy: Clinical Impact, Potential Mechanisms, and New Innovative Treatment Options
- (2020) Wolfgang Löscher et al. PHARMACOLOGICAL REVIEWS
- ROS Generation in Microglia: Understanding Oxidative Stress and Inflammation in Neurodegenerative Disease
- (2020) Dominic S. A. Simpson et al. Antioxidants
- Role of astroglial toll-like receptors (TLRs) in central nervous system infections, injury and neurodegenerative diseases
- (2020) Lun Li et al. BRAIN BEHAVIOR AND IMMUNITY
- Antifungal drug miconazole ameliorated memory deficits in a mouse model of LPS-induced memory loss through targeting iNOS
- (2020) In Jun Yeo et al. Cell Death & Disease
- Brain Inflammation and Seizures: Evolving Concepts and New Findings in the Last 2 Decades
- (2020) Annamaria Vezzani Epilepsy Currents
- Celecoxib Exerts Neuroprotective Effects in β-Amyloid-Treated SH-SY5Y Cells Through the Regulation of Heme Oxygenase-1: Novel Insights for an Old Drug
- (2020) Emanuela Mhillaj et al. Frontiers in Cell and Developmental Biology
- Cotinine and 6-Hydroxy-L-Nicotine Reverses Memory Deficits and Reduces Oxidative Stress in Aβ25-35-Induced Rat Model of Alzheimer’s Disease
- (2020) Razvan Stefan Boiangiu et al. Antioxidants
- Can We Treat Neuroinflammation in Alzheimer’s Disease?
- (2020) Sandra Sánchez-Sarasúa et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Protection induced by estradiol benzoate in the MPP+ rat model of Parkinson's disease is associated with the regulation of the inflammatory cytokine profile in the nigro striatum
- (2020) Yoshajandith Aguirre-Vidal et al. JOURNAL OF NEUROIMMUNOLOGY
- Revisiting the role of neurotransmitters in epilepsy: An updated review
- (2020) Enes Akyuz et al. LIFE SCIENCES
- Neuroinflammation and microglial activation in Alzheimer disease: where do we go from here?
- (2020) Fangda Leng et al. Nature Reviews Neurology
- The NLRP3 inflammasome inhibitor OLT1177 rescues cognitive impairment in a mouse model of Alzheimer’s disease
- (2020) Niklas Lonnemann et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Neuron-Astrocyte Interactions in Parkinson’s Disease
- (2020) Ikuko Miyazaki et al. Cells
- Sinapic Acid Alleviates Oxidative Stress and Neuro-Inflammatory Changes in Sporadic Model of Alzheimer’s Disease in Rats
- (2020) Vandna Verma et al. Brain Sciences
- Activation of microglia and astrocytes: a roadway to neuroinflammation and Alzheimer’s disease
- (2019) Darshpreet Kaur et al. INFLAMMOPHARMACOLOGY
- Protective effects of lycopene on kainic acid-induced seizures
- (2019) Sen Li et al. EPILEPSY RESEARCH
- Neuroinflammation, the thread connecting neurological disease
- (2019) Roberta Brambilla ACTA NEUROPATHOLOGICA
- Adalimumab improves cognitive impairment, exerts neuroprotective effects and attenuates neuroinflammation in an Aβ1-40-injected mouse model of Alzheimer's disease
- (2019) JIAE Park et al. CYTOTHERAPY
- Inflammasomes in neuroinflammatory and neurodegenerative diseases
- (2019) Sofie Voet et al. EMBO Molecular Medicine
- Cordycepin mitigates MPTP-induced Parkinson's disease through inhibiting TLR/NF-κB signaling pathway
- (2019) Chunyan Cheng et al. LIFE SCIENCES
- Multi-faceted therapeutic strategy for treatment of Alzheimer's disease by concurrent administration of etodolac and α-tocopherol
- (2019) Khaled H. Elfakhri et al. NEUROBIOLOGY OF DISEASE
- A Unifying Hypothesis for Alzheimer’s Disease: From Plaques to Neurodegeneration
- (2019) Frances A. Edwards TRENDS IN NEUROSCIENCES
- Neuroprotective and anti-inflammatory effects of isoliquiritigenin in kainic acid-induced epileptic rats via the TLR4/MYD88 signaling pathway
- (2019) Xiaobo Zhu et al. INFLAMMOPHARMACOLOGY
- Cytokine Research in Depression: Principles, Challenges, and Open Questions
- (2019) Hubertus Himmerich et al. Frontiers in Psychiatry
- Targeting oxidative stress improves disease outcomes in a rat model of acquired epilepsy
- (2019) Alberto Pauletti et al. BRAIN
- TLR3 preconditioning induces anti-inflammatory and anti-ictogenic effects in mice mediated by the IRF3/IFN-β axis
- (2019) C. Kostoula et al. BRAIN BEHAVIOR AND IMMUNITY
- Baicalein improves cognitive deficits and hippocampus impairments in temporal lobe epilepsy rats
- (2019) Xu Qian et al. BRAIN RESEARCH
- Sulfasalazine decreases mouse cortical hyperexcitability
- (2019) Oscar Alcoreza et al. EPILEPSIA
- Alzheimer’s disease: pathogenesis, diagnostics, and therapeutics
- (2019) Sneham Tiwari et al. International Journal of Nanomedicine
- Mulberrin attenuates 1-methyl-4-phenyl-1,2,3,6- tetrahydropyridine (MPTP)-induced Parkinson’s disease by promoting Wnt/β-catenin signaling pathway
- (2019) Wenhui Cao et al. JOURNAL OF CHEMICAL NEUROANATOMY
- Neuroinflammation — a common thread in neurological disorders
- (2019) Nils Erik Gilhus et al. Nature Reviews Neurology
- Neuroinflammatory pathways as treatment targets and biomarkers in epilepsy
- (2019) Annamaria Vezzani et al. Nature Reviews Neurology
- Rosmarinic acid improves oxidative stress parameters and mitochondrial respiratory chain activity following 4-aminopyridine and picrotoxin-induced seizure in mice
- (2019) Jordana Griebler Luft et al. NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY
- Oxymatrine can attenuate pathological deficits of Alzheimer's disease mice through regulation of neuroinflammation
- (2019) Yun Chen et al. JOURNAL OF NEUROIMMUNOLOGY
- Anticonvulsant and Neuroprotective Effects of Paeonol in Epileptic Rats
- (2019) Dong-Hai Liu et al. NEUROCHEMICAL RESEARCH
- Effect of Ibuprofen on Autophagy of Astrocytes During Pentylenetetrazol-Induced Epilepsy and its Significance: An Experimental Study
- (2019) Jiangtao Peng et al. NEUROCHEMICAL RESEARCH
- Inflammation and reactive oxygen species as disease modifiers in epilepsy
- (2019) Gaetano Terrone et al. NEUROPHARMACOLOGY
- Novel effect of Arthrocen (avocado/soy unsaponifiables) on pentylenetetrazole-induced seizure threshold in mice: Role of GABAergic pathway
- (2019) Ramin Goudarzi et al. EPILEPSY & BEHAVIOR
- Ferulic acid ameliorates pentylenetetrazol-induced seizures by reducing neuron cell death
- (2019) Shu-Hong Zhang et al. EPILEPSY RESEARCH
- Targeting high-mobility group box protein 1 (HMGB1) in pediatric traumatic brain injury: Chronic neuroinflammatory, behavioral, and epileptogenic consequences
- (2019) Kyria M. Webster et al. EXPERIMENTAL NEUROLOGY
- The role of innate immune responses and neuroinflammation in amyloid accumulation and progression of Alzheimer's disease
- (2019) Alessandra Webers et al. IMMUNOLOGY AND CELL BIOLOGY
- Astragaloside IV ameliorates motor deficits and dopaminergic neuron degeneration via inhibiting neuroinflammation and oxidative stress in a Parkinson's disease mouse model
- (2019) Cong Yang et al. INTERNATIONAL IMMUNOPHARMACOLOGY
- Review on Cross Talk between Neurotransmitters and Neuroinflammation in Striatum and Cerebellum in the Mediation of Motor Behaviour
- (2019) Dayang Yasmin Abg Abd Wahab et al. Biomed Research International
- Minocycline at 2 Different Dosages vs Placebo for Patients With Mild Alzheimer Disease
- (2019) Robert Howard et al. JAMA Neurology
- Neuroinflammation in Post-Traumatic Epilepsy: Pathophysiology and Tractable Therapeutic Targets
- (2019) Rishabh Sharma et al. Brain Sciences
- The global burden of neurological disorders: translating evidence into policy
- (2019) Valery L Feigin et al. LANCET NEUROLOGY
- Antioxidant and anti-inflammatory effects of dexrazoxane on dopaminergic neuron degeneration in rodent models of Parkinson's disease
- (2019) Meng Mei et al. NEUROPHARMACOLOGY
- Antagonizing peroxisome proliferator-activated receptor γ facilitates M1-to-M2 shift of microglia by enhancing autophagy via the LKB1-AMPK signaling pathway
- (2018) Juan Ji et al. AGING CELL
- Peripheral immune cells infiltrate into sites of secondary neurodegeneration after ischemic stroke
- (2018) K.A. Jones et al. BRAIN BEHAVIOR AND IMMUNITY
- High Mobility Group Box 1 is a novel pathogenic factor and a mechanistic biomarker for epilepsy
- (2018) Teresa Ravizza et al. BRAIN BEHAVIOR AND IMMUNITY
- The Role of Inflammation in Neurological Disorders
- (2018) Diana Degan et al. CURRENT PHARMACEUTICAL DESIGN
- Peripheral monocyte entry is required for alpha-Synuclein induced inflammation and Neurodegeneration in a model of Parkinson disease
- (2018) Ashley S. Harms et al. EXPERIMENTAL NEUROLOGY
- Integrated communications between cyclooxygenase-2 and Alzheimer’s disease
- (2018) Pei-Pei Guan et al. FASEB JOURNAL
- Parkin deficiency modulates NLRP3 inflammasome activation by attenuating an A20-dependent negative feedback loop
- (2018) François Mouton-Liger et al. GLIA
- The role of inflammation in the development of epilepsy
- (2018) Amna Rana et al. Journal of Neuroinflammation
- HMGB1 promotes the starvation-induced autophagic degradation of α-synuclein in SH-SY5Y cells Atg 5-dependently
- (2018) Yi Guan et al. LIFE SCIENCES
- Ligation of free HMGB1 to TLR2 in the absence of ligand is negatively regulated by the C-terminal tail domain
- (2018) Hannah Aucott et al. MOLECULAR MEDICINE
- (-)-Epigallocatechin-3-gallate modulates peripheral immunity in the MPTP-induced mouse model of Parkinson's disease
- (2018) Tingting Zhou et al. Molecular Medicine Reports
- NLRP3-dependent synaptic plasticity deficit in an Alzheimer's disease amyloidosis model in vivo
- (2018) Yingjie Qi et al. NEUROBIOLOGY OF DISEASE
- Alpha-synuclein: Pathology, mitochondrial dysfunction and neuroinflammation in Parkinson’s disease
- (2018) Emily M. Rocha et al. NEUROBIOLOGY OF DISEASE
- Addition of pyridoxine to prednisolone in the treatment of infantile spasms: A pilot, randomized controlled trial
- (2018) Suvasini Sharma et al. NEUROLOGY INDIA
- Celecoxib Prevents Cognitive Impairment and Neuroinflammation in Soluble Amyloid β-treated Rats
- (2018) Emanuela Mhillaj et al. NEUROSCIENCE
- Immunomodulatory effect of Celecoxib on HMGB1/TLR4 pathway in a recurrent seizures model in immature rats
- (2018) Mariana Morales-Sosa et al. PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR
- Microglial Phagocytosis and Its Regulation: A Therapeutic Target in Parkinson’s Disease?
- (2018) Elzbieta Janda et al. Frontiers in Molecular Neuroscience
- Tau and neuroinflammation: What impact for Alzheimer's Disease and Tauopathies?
- (2018) Cyril Laurent et al. Biomedical Journal
- The role of mitochondria in NLRP3 inflammasome activation
- (2018) Qiuyun Liu et al. MOLECULAR IMMUNOLOGY
- A new approach for Alzheimer's disease treatment through P-gp regulation via ibuprofen
- (2018) Chengxiang Zhang et al. PATHOLOGY RESEARCH AND PRACTICE
- HMGB1: A Common Biomarker and Potential Target for TBI, Neuroinflammation, Epilepsy, and Cognitive Dysfunction
- (2018) Yam Nath Paudel et al. Frontiers in Neuroscience
- Non-steroidal anti-inflammatory drugs and risk of Parkinson’s disease in the elderly population: a meta-analysis
- (2018) Tahmina Nasrin Poly et al. EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY
- Effects of a medium-chain triglyceride-based ketogenic formula on cognitive function in patients with mild-to-moderate Alzheimer’s disease
- (2018) Miho Ota et al. NEUROSCIENCE LETTERS
- Nonsteroidal anti-inflammatory drugs in clinical and experimental epilepsy
- (2017) Beatrice Mihaela Radu et al. EPILEPSY RESEARCH
- Cyclooxygenase-2 inhibitors differentially attenuate pentylenetetrazol-induced seizures and increase of pro- and anti-inflammatory cytokine levels in the cerebral cortex and hippocampus of mice
- (2017) Fernanda Rossatto Temp et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- NLRP3 Inflammasome Activation in a Transgenic Amyotrophic Lateral Sclerosis Model
- (2017) Agnese Gugliandolo et al. INFLAMMATION
- The Oral Pretreatment of Glycyrrhizin Prevents Surgery-Induced Cognitive Impairment in Aged Mice by Reducing Neuroinflammation and Alzheimer’s-Related Pathology via HMGB1 Inhibition
- (2017) Zhong-Hong Kong et al. JOURNAL OF MOLECULAR NEUROSCIENCE
- Inflammation in epileptogenesis after traumatic brain injury
- (2017) Kyria M. Webster et al. Journal of Neuroinflammation
- Resveratrol regulates neuro-inflammation and induces adaptive immunity in Alzheimer’s disease
- (2017) Charbel Moussa et al. Journal of Neuroinflammation
- NLRP3 Inflammasome Inhibitor Ameliorates Amyloid Pathology in a Mouse Model of Alzheimer’s Disease
- (2017) Jun Yin et al. MOLECULAR NEUROBIOLOGY
- Blockade of the IL-1R1/TLR4 pathway mediates disease-modification therapeutic effects in a model of acquired epilepsy
- (2017) Valentina Iori et al. NEUROBIOLOGY OF DISEASE
- Cerebrospinal Fluid NLRP3 is Increased After Severe Traumatic Brain Injury in Infants and Children
- (2017) Jessica S. Wallisch et al. Neurocritical Care
- Modulation of neuroinflammation and pathology in the 5XFAD mouse model of Alzheimer's disease using a biased and selective beta-1 adrenergic receptor partial agonist
- (2017) Pooneh Memar Ardestani et al. NEUROPHARMACOLOGY
- Inhibitory effect of punicalagin on lipopolysaccharide-induced neuroinflammation, oxidative stress and memory impairment via inhibition of nuclear factor-kappaB
- (2017) Young Eun Kim et al. NEUROPHARMACOLOGY
- Atorvastatin Prevents Early Oxidative Events and Modulates Inflammatory Mediators in the Striatum Following Intranasal 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) Administration in Rats
- (2017) Naiani F. Marques et al. NEUROTOXICITY RESEARCH
- Minocycline reduces inflammatory parameters in the brain structures and serum and reverses memory impairment caused by the administration of amyloid β (1-42) in mice
- (2017) Michelle Lima Garcez et al. PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY
- Pyroptosis: Gasdermin-Mediated Programmed Necrotic Cell Death
- (2017) Jianjin Shi et al. TRENDS IN BIOCHEMICAL SCIENCES
- Investigations into Hypoxia and Oxidative Stress at the Optic Nerve Head in a Rat Model of Glaucoma
- (2017) Glyn Chidlow et al. Frontiers in Neuroscience
- Mitochondria-Derived Damage-Associated Molecular Patterns in Neurodegeneration
- (2017) Heather M. Wilkins et al. Frontiers in Immunology
- Tangeretin inhibits neurodegeneration and attenuates inflammatory responses and behavioural deficits in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced Parkinson’s disease dementia in rats
- (2017) Jin-song Yang et al. INFLAMMOPHARMACOLOGY
- Parkinson disease
- (2017) Werner Poewe et al. Nature Reviews Disease Primers
- Inflammatory aspects of epileptogenesis: contribution of molecular inflammatory mechanisms
- (2016) Feyza Alyu et al. ACTA NEUROPSYCHIATRICA
- Neuroinflammation in Alzheimer's disease: Current evidence and future directions
- (2016) Valeria Calsolaro et al. Alzheimers & Dementia
- Microglia in the TBI brain: The good, the bad, and the dysregulated
- (2016) David J. Loane et al. EXPERIMENTAL NEUROLOGY
- Neuroinflammation pathways: a general review
- (2016) Tara Shabab et al. INTERNATIONAL JOURNAL OF NEUROSCIENCE
- Mitochondrial dysfunction in Parkinson's disease
- (2016) Anindita Bose et al. JOURNAL OF NEUROCHEMISTRY
- Clozapine metabolites protect dopaminergic neurons through inhibition of microglial NADPH oxidase
- (2016) Lulu Jiang et al. Journal of Neuroinflammation
- Infliximab reduces peripheral inflammation, neuroinflammation, and extracellular GABA in the cerebellum and improves learning and motor coordination in rats with hepatic encephalopathy
- (2016) Sherry Dadsetan et al. Journal of Neuroinflammation
- Monocyte-Derived Macrophages Contribute to Spontaneous Long-Term Functional Recovery after Stroke in Mice
- (2016) S. Wattananit et al. JOURNAL OF NEUROSCIENCE
- Distinct Nrf2 Signaling Mechanisms of Fumaric Acid Esters and Their Role in Neuroprotection against 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine-Induced Experimental Parkinson's-Like Disease
- (2016) M. Ahuja et al. JOURNAL OF NEUROSCIENCE
- Neuroprotective and anti-inflammatory effects of morin in a murine model of Parkinson's disease
- (2016) Kyung Moon Lee et al. JOURNAL OF NEUROSCIENCE RESEARCH
- Matrix Metalloproteinase 9 in Epilepsy: The Role of Neuroinflammation in Seizure Development
- (2016) Elżbieta Bronisz et al. MEDIATORS OF INFLAMMATION
- Therapeutic effects of paeonol on methyl-4-phenyl-1,2,3,6-tetrahydropyridine/probenecid-induced Parkinson's disease in mice
- (2016) Xiaojin Shi et al. Molecular Medicine Reports
- The NLRP3 and NLRP1 inflammasomes are activated in Alzheimer’s disease
- (2016) Marina Saresella et al. Molecular Neurodegeneration
- Genome-wide association analysis identifies TXNRD2, ATXN2 and FOXC1 as susceptibility loci for primary open-angle glaucoma
- (2016) Jessica N Cooke Bailey et al. NATURE GENETICS
- A polarizing question: do M1 and M2 microglia exist?
- (2016) Richard M Ransohoff NATURE NEUROSCIENCE
- Chronic 5-HT3 receptor antagonism ameliorates seizures and associated memory deficit in pentylenetetrazole-kindled mice
- (2016) Awanish Mishra et al. NEUROSCIENCE
- Modulation of LOX and COX pathways via inhibition of amyloidogenesis contributes to mitoprotection against β-amyloid oligomer-induced toxicity in an animal model of Alzheimer's disease in rats
- (2016) Jaspreet Kalra et al. PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR
- Inflammatory neuroprotection following traumatic brain injury
- (2016) M. V. Russo et al. SCIENCE
- Fenamate NSAIDs inhibit the NLRP3 inflammasome and protect against Alzheimer’s disease in rodent models
- (2016) Michael J. D. Daniels et al. Nature Communications
- Inhibitory effect of thiacremonone on MPTP-induced dopaminergic neurodegeneration through inhibition of p38 activation
- (2016) Chul Ju Hwang et al. Oncotarget
- Inflammatory aspects of epileptogenesis: contribution of molecular inflammatory mechanisms
- (2016) Feyza Alyu et al. ACTA NEUROPSYCHIATRICA
- Serotonin Modulates Developmental Microglia via 5-HT2B Receptors: Potential Implication during Synaptic Refinement of Retinogeniculate Projections
- (2015) Marta Kolodziejczak et al. ACS Chemical Neuroscience
- Effects of systemic Thalidomide and intracerebroventricular Etanercept and Infliximab administration in a Streptozotocin induced dementia model in rats
- (2015) H. Kübra Elçioğlu et al. ACTA HISTOCHEMICA
- Partial depletion of the proinflammatory monocyte population is neuroprotective in the myenteric plexus but not in the basal ganglia in a MPTP mouse model of Parkinson’s disease
- (2015) M. Côté et al. BRAIN BEHAVIOR AND IMMUNITY
- Antiepileptogenic effects of the selective COX-2 inhibitor etoricoxib, on the development of spontaneous absence seizures in WAG/Rij rats
- (2015) Rita Citraro et al. BRAIN RESEARCH BULLETIN
- Anti-neuroinflammatory effects of DPTP, a novel synthetic clovamide derivative in in vitro and in vivo model of neuroinflammation
- (2015) Hyung-Woo Lim et al. BRAIN RESEARCH BULLETIN
- Non-Steroidal Anti-Inflammatory Drugs as a Treatment for Alzheimer’s Disease: A Systematic Review and Meta-Analysis of Treatment Effect
- (2015) Marina Miguel-Álvarez et al. DRUGS & AGING
- Anticonvulsant activity of the cyclooxygenase-2 (COX-2) inhibitor etoricoxib in pentylenetetrazole-kindled rats is associated with memory impairment
- (2015) Jatinder Katyal et al. EPILEPSY & BEHAVIOR
- Lycopene abrogates Aβ(1–42)-mediated neuroinflammatory cascade in an experimental model of Alzheimer’s disease
- (2015) Anand Kamal Sachdeva et al. JOURNAL OF NUTRITIONAL BIOCHEMISTRY
- Tanshinone IIA prevents the loss of nigrostriatal dopaminergic neurons by inhibiting NADPH oxidase and iNOS in the MPTP model of Parkinson's disease
- (2015) Bo Ren et al. JOURNAL OF THE NEUROLOGICAL SCIENCES
- GABA A currents are decreased by IL-1β in epileptogenic tissue of patients with temporal lobe epilepsy: implications for ictogenesis
- (2015) Cristina Roseti et al. NEUROBIOLOGY OF DISEASE
- α-Asarone attenuates microglia-mediated neuroinflammation by inhibiting NF kappa B activation and mitigates MPTP-induced behavioral deficits in a mouse model of Parkinson's disease
- (2015) Byung-Wook Kim et al. NEUROPHARMACOLOGY
- Co-administration of subtherapeutic diazepam enhances neuroprotective effect of COX-2 inhibitor, NS-398, after lithium pilocarpine-induced status epilepticus
- (2015) C.C. Trandafir et al. NEUROSCIENCE
- Neuroprotective and anti-inflammatory properties of a novel non-thiazolidinedione PPARγ agonist in vitro and in MPTP-treated mice
- (2015) D. Lecca et al. NEUROSCIENCE
- Mitochondria: diversity in the regulation of the NLRP3 inflammasome
- (2015) Prajwal Gurung et al. TRENDS IN MOLECULAR MEDICINE
- Microglia constitute a barrier that prevents neurotoxic protofibrillar Aβ42 hotspots around plaques
- (2015) Carlo Condello et al. Nature Communications
- PINK1-Parkin-Mediated Mitophagy Protects Mitochondrial Integrity and Prevents Metabolic Stress-Induced Endothelial Injury
- (2015) Weiwei Wu et al. PLoS One
- Measurement of Systemic Mitochondrial Function in Advanced Primary Open-Angle Glaucoma and Leber Hereditary Optic Neuropathy
- (2015) Nicole J Van Bergen et al. PLoS One
- Interleukin-1 Antagonist Anakinra in Amyotrophic Lateral Sclerosis—A Pilot Study
- (2015) André Maier et al. PLoS One
- Oxidative stress induces autophagy in response to multiple noxious stimuli in retinal ganglion cells
- (2014) Wen-jian Lin et al. Autophagy
- Mechanisms and Functions of Inflammasomes
- (2014) Mohamed Lamkanfi et al. CELL
- Ontogeny and Functions of Central Nervous System Macrophages
- (2014) Atsuko Katsumoto et al. JOURNAL OF IMMUNOLOGY
- Atacicept in multiple sclerosis (ATAMS): a randomised, placebo-controlled, double-blind, phase 2 trial
- (2014) Ludwig Kappos et al. LANCET NEUROLOGY
- Role of Inflammatory Mediators in the Pathogenesis of Epilepsy
- (2014) Tadayuki Shimada et al. MEDIATORS OF INFLAMMATION
- HMGB1 in health and disease
- (2014) Rui Kang et al. MOLECULAR ASPECTS OF MEDICINE
- Inflammasomes in the CNS
- (2014) John G. Walsh et al. NATURE REVIEWS NEUROSCIENCE
- Effects of Naproxen on Immune Responses in a Colchicine-Induced Rat Model of Alzheimer's Disease
- (2014) Susmita Sil et al. NEUROIMMUNOMODULATION
- Neuroprotective effects of the andrographolide analogue AL-1 in the MPP+/MPTP-induced Parkinson's disease model in vitro and in mice
- (2014) Zaijun Zhang et al. PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR
- PPAR-α agonist fenofibrate protects against the damaging effects of MPTP in a rat model of Parkinson's disease
- (2014) Janaína K. Barbiero et al. PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY
- Increased Expression of Matrix Metalloproteinase-9 in Patients with Temporal Lobe Epilepsy
- (2014) Goksemin Acar et al. Turkish Neurosurgery
- 6-Shogaol, an active compound of ginger, protects dopaminergic neurons in Parkinson's disease models via anti-neuroinflammation
- (2013) Gunhyuk Park et al. ACTA PHARMACOLOGICA SINICA
- Atorvastatin improves cognitive, emotional and motor impairments induced by intranasal 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) administration in rats, an experimental model of Parkinson's disease
- (2013) Adalberto A. Castro et al. BRAIN RESEARCH
- Does aspirin use make it harder to collect seizures during elective video-EEG telemetry?
- (2013) Rachel M. Godfred et al. EPILEPSY & BEHAVIOR
- S-allyl cysteine protects against MPTP-induced striatal and nigral oxidative neurotoxicity in mice: Participation of Nrf2
- (2013) Esperanza García et al. FREE RADICAL RESEARCH
- Zinc oxide nanoparticles decrease the expression and activity of plasma membrane calcium ATPase, disrupt the intracellular calcium homeostasis in rat retinal ganglion cells
- (2013) Dadong Guo et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- Innate Immunity in the CNS: Redefining the Relationship between the CNS and Its Environment
- (2013) Antoine Lampron et al. NEURON
- Nobiletin treatment improves motor and cognitive deficits seen in MPTP-induced Parkinson model mice
- (2013) Y. Yabuki et al. NEUROSCIENCE
- Epigenetics and the Modulation of Neuroinflammation
- (2013) Gwenn A. Garden Neurotherapeutics
- Long-Term Treatment of Thalidomide Ameliorates Amyloid-Like Pathology through Inhibition of β-Secretase in a Mouse Model of Alzheimer’s Disease
- (2013) Ping He et al. PLoS One
- Autophagy and apoptosis dysfunction in neurodegenerative disorders
- (2013) Saeid Ghavami et al. PROGRESS IN NEUROBIOLOGY
- Structure and Function of Parkin, PINK1, and DJ-1, the Three Musketeers of Neuroprotection
- (2013) Jean-François Trempe et al. Frontiers in Neurology
- Autophagy regulates trans fatty acid-mediated apoptosis in primary cardiac myofibroblasts
- (2012) Saeid Ghavami et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Fetal Brain Lesions in Tuberous Sclerosis Complex: TORC1 Activation and Inflammation
- (2012) Avanita S. Prabowo et al. BRAIN PATHOLOGY
- Oxidative stress and mitochondrial dysfunction in glaucoma
- (2012) Vicki Chrysostomou et al. CURRENT OPINION IN PHARMACOLOGY
- Activation of Invariant NKT Cells in Early Phase of Experimental Autoimmune Encephalomyelitis Results in Differentiation of Ly6Chi Inflammatory Monocyte to M2 Macrophages and Improved Outcome
- (2012) L. Denney et al. JOURNAL OF IMMUNOLOGY
- Brain leukocyte infiltration initiated by peripheral inflammation or experimental autoimmune encephalomyelitis occurs through pathways connected to the CSF-filled compartments of the forebrain and midbrain
- (2012) Charlotte Schmitt et al. Journal of Neuroinflammation
- L-glutamate released from activated microglia downregulates astrocytic L-glutamate transporter expression in neuroinflammation: the ‘collusion’ hypothesis for increased extracellular L-glutamate concentration in neuroinflammation
- (2012) Junpei Takaki et al. Journal of Neuroinflammation
- Neuronal Glutamate Transporters Regulate Glial Excitatory Transmission
- (2012) M.-C. Tsai et al. JOURNAL OF NEUROSCIENCE
- HMGB1 in Development and Diseases of the Central Nervous System
- (2012) Ping Fang et al. MOLECULAR NEUROBIOLOGY
- Nicotinamide forestalls pathology and cognitive decline in Alzheimer mice: evidence for improved neuronal bioenergetics and autophagy procession
- (2012) Dong Liu et al. NEUROBIOLOGY OF AGING
- Telomere Shortening and Alzheimer’s Disease
- (2012) Zhiyou Cai et al. NEUROMOLECULAR MEDICINE
- Rosiglitazone, a PPAR-γ agonist, protects against striatal dopaminergic neurodegeneration induced by 6-OHDA lesions in the substantia nigra of rats
- (2012) Eun Young Lee et al. TOXICOLOGY LETTERS
- Microglia Function in Alzheimer’s Disease
- (2012) Egle Solito et al. Frontiers in Pharmacology
- Brain inflammation as a biomarker in epilepsy
- (2011) Annamaria Vezzani et al. Biomarkers in Medicine
- Cytokines and brain excitability
- (2011) Michael A. Galic et al. FRONTIERS IN NEUROENDOCRINOLOGY
- Spatial and temporal correlation between neuron loss and neuroinflammation in a mouse model of neuronopathic Gaucher disease
- (2011) T. Farfel-Becker et al. HUMAN MOLECULAR GENETICS
- Virus-triggered autophagy in viral hepatitis - possible novel strategies for drug development
- (2011) S. M. Alavian et al. JOURNAL OF VIRAL HEPATITIS
- Infiltrating monocytes trigger EAE progression, but do not contribute to the resident microglia pool
- (2011) Bahareh Ajami et al. NATURE NEUROSCIENCE
- Protective Effects of Chunghyuldan against ROS-mediated Neuronal Cell Death in Models of Parkinson’s Disease
- (2010) Hyo Geun Kim et al. BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY
- Superoxide is an associated signal for apoptosis in axonal injury
- (2010) A. Kanamori et al. BRAIN
- Celecoxib treatment restores pharmacosensitivity in a rat model of pharmacoresistant epilepsy
- (2010) J Schlichtiger et al. BRITISH JOURNAL OF PHARMACOLOGY
- Mechanisms Underlying Inflammation in Neurodegeneration
- (2010) Christopher K. Glass et al. CELL
- The COX-2 inhibitor parecoxib is neuroprotective but not antiepileptogenic in the pilocarpine model of temporal lobe epilepsy
- (2010) Nadine Polascheck et al. EXPERIMENTAL NEUROLOGY
- Regulatory T Cells Attenuate Th17 Cell-Mediated Nigrostriatal Dopaminergic Neurodegeneration in a Model of Parkinson’s Disease
- (2010) Ashley D. Reynolds et al. JOURNAL OF IMMUNOLOGY
- Autophagy: cellular and molecular mechanisms
- (2010) Danielle Glick et al. JOURNAL OF PATHOLOGY
- Anti-inflammatory drugs and risk of Parkinson disease: A meta-analysis
- (2010) J. J. Gagne et al. NEUROLOGY
- Regulation of Mammalian Autophagy in Physiology and Pathophysiology
- (2010) Brinda Ravikumar et al. PHYSIOLOGICAL REVIEWS
- Rituximab in patients with primary progressive multiple sclerosis: Results of a randomized double-blind placebo-controlled multicenter trial
- (2009) Kathleen Hawker et al. ANNALS OF NEUROLOGY
- Microglia-aging: Roles of microglial lysosome- and mitochondria-derived reactive oxygen species in brain aging
- (2009) Hiroshi Nakanishi et al. BEHAVIOURAL BRAIN RESEARCH
- Critical Regulation of Early Th17 Cell Differentiation by Interleukin-1 Signaling
- (2009) Yeonseok Chung et al. IMMUNITY
- NSAIDs prevent, but do not reverse, neuronal cell cycle reentry in a mouse model of Alzheimer disease
- (2009) Nicholas H. Varvel et al. JOURNAL OF CLINICAL INVESTIGATION
- Microglia in ALS: The Good, The Bad, and The Resting
- (2009) Jenny S. Henkel et al. Journal of Neuroimmune Pharmacology
- Neuroprotective and toxic changes in microglia in neurodegenerative disease
- (2009) Makoto Sawada PARKINSONISM & RELATED DISORDERS
- [11C]-PK11195 PET: Quantification of neuroinflammation and a monitor of anti-inflammatory treatment in Parkinson's disease?
- (2009) A.L. Bartels et al. PARKINSONISM & RELATED DISORDERS
- Protective effect of cyclooxygenase (COX)-inhibitors against drug-induced catatonia and MPTP-induced striatal lesions in rats
- (2009) Amit Gupta et al. PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR
- Tripartite synapses: astrocytes process and control synaptic information
- (2009) Gertrudis Perea et al. TRENDS IN NEUROSCIENCES
- Excitatory amino acid transporter expression by astrocytes is neuroprotective against microglial excitotoxicity
- (2008) Jianfeng Liang et al. BRAIN RESEARCH
- Efficacy and prognosis of a short course of prednisolone therapy for pediatric epilepsy
- (2008) S.J. You et al. EUROPEAN JOURNAL OF PAEDIATRIC NEUROLOGY
- Blockade of microglial glutamate release protects against ischemic brain injury
- (2008) Hideyuki Takeuchi et al. EXPERIMENTAL NEUROLOGY
- GM-CSF mediates autoimmunity by enhancing IL-6–dependent Th17 cell development and survival
- (2008) Ivo Sonderegger et al. JOURNAL OF EXPERIMENTAL MEDICINE
- A Molecular Platform in Neurons Regulates Inflammation after Spinal Cord Injury
- (2008) J. P. de Rivero Vaccari et al. JOURNAL OF NEUROSCIENCE
- Inflammatory Response in the Hippocampus of PS1M146L/APP751SL Mouse Model of Alzheimer's Disease: Age-Dependent Switch in the Microglial Phenotype from Alternative to Classic
- (2008) S. Jimenez et al. JOURNAL OF NEUROSCIENCE
- Curcumin Structure-Function, Bioavailability, and Efficacy in Models of Neuroinflammation and Alzheimer's Disease
- (2008) A. N. Begum et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
- Ibuprofen modifies cognitive disease progression in an Alzheimer’s mouse model
- (2008) D. Van Dam et al. JOURNAL OF PSYCHOPHARMACOLOGY
- Efficacy and safety of tarenflurbil in mild to moderate Alzheimer's disease: a randomised phase II trial
- (2008) Gordon K Wilcock et al. LANCET NEUROLOGY
- B-Cell Depletion with Rituximab in Relapsing–Remitting Multiple Sclerosis
- (2008) Stephen L. Hauser et al. NEW ENGLAND JOURNAL OF MEDICINE
- A 5-HT2A receptor inverse agonist, ACP-103, reduces tremor in a rat model and levodopa-induced dyskinesias in a monkey model
- (2008) K VANOVER et al. PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR
- Glial toll-like receptor signaling in central nervous system infection and autoimmunity
- (2007) Pamela A. Carpentier et al. BRAIN BEHAVIOR AND IMMUNITY
- Innate and adaptive immunity during epileptogenesis and spontaneous seizures: Evidence from experimental models and human temporal lobe epilepsy
- (2007) Teresa Ravizza et al. NEUROBIOLOGY OF DISEASE
- Activation of microglia by secreted amyloid precursor protein evokes release of glutamate by cystine exchange and attenuates synaptic function
- (2003) Steven W. Barger et al. JOURNAL OF NEUROCHEMISTRY
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