Inflammation in epileptogenesis after traumatic brain injury

Inflammatory aspects of epileptogenesis: contribution of molecular inflammatory mechanisms

(2016) Feyza Alyu et al.   ACTA NEUROPSYCHIATRICA

Risk factors for subsequent febrile seizures in the FEBSTAT study

(2016) Dale C. Hesdorffer et al.   EPILEPSIA

GABAergic networks jump-start focal seizures

(2016) Marco de Curtis et al.   EPILEPSIA

Activation of GABA A receptors controls mesiotemporal lobe epilepsy despite changes in chloride transporters expression: In vivo and in silico approach

(2016) Séverine Stamboulian-Platel et al.   EXPERIMENTAL NEUROLOGY

Specific imbalance of excitatory/inhibitory signaling establishes seizure onset pattern in temporal lobe epilepsy

(2016) Massimo Avoli et al.   JOURNAL OF NEUROPHYSIOLOGY

Which insights have we gained from the kindling and post-status epilepticus models?

(2016) Jan A. Gorter et al.   JOURNAL OF NEUROSCIENCE METHODS

Animal models of temporal lobe epilepsy following systemic chemoconvulsant administration

(2016) Maxime Lévesque et al.   JOURNAL OF NEUROSCIENCE METHODS

Functional aspects of early brain development are preserved in tuberous sclerosis complex (TSC) epileptogenic lesions

(2016) Gabriele Ruffolo et al.   NEUROBIOLOGY OF DISEASE

Neuroprotective levels of IGF-1 exacerbate epileptogenesis after brain injury

(2016) Yu Song et al.   Scientific Reports

Inflammatory aspects of epileptogenesis: contribution of molecular inflammatory mechanisms

(2016) Feyza Alyu et al.   ACTA NEUROPSYCHIATRICA

Role of Anticonvulsants in the Management of Posttraumatic Epilepsy

(2016) Batool F. Kirmani et al.   Frontiers in Neurology

How eukaryotic genes are transcribed

(2016) Bryan J. Venters et al.   CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY

IL-1β associations with posttraumatic epilepsy development: A genetics and biomarker cohort study

(2015) Matthew L. Diamond et al.   EPILEPSIA

Clinical evidence of inflammation driving secondary brain injury

(2015) Holly E. Hinson et al.   Journal of Trauma and Acute Care Surgery

Albumin induces excitatory synaptogenesis through astrocytic TGF-β/ALK5 signaling in a model of acquired epilepsy following blood–brain barrier dysfunction

(2015) Itai Weissberg et al.   NEUROBIOLOGY OF DISEASE

Therapeutic window for cyclooxygenase-2 related anti-inflammatory therapy after status epilepticus

(2015) Jianxiong Jiang et al.   NEUROBIOLOGY OF DISEASE

Clinical evidence of inflammation driving secondary brain injury

(2015) Holly E. Hinson et al.   Journal of Trauma and Acute Care Surgery

Traumatic Brain Injury Increases Cortical Glutamate Network Activity by Compromising GABAergic Control

(2014) David Cantu et al.   CEREBRAL CORTEX

Recombinant Human Interleukin-1 Receptor Antagonist in Severe Traumatic Brain Injury: A Phase II Randomized Control Trial

(2014) Adel Helmy et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

The Epidemiology of Traumatic Brain Injury in Children and Youths

(2014) David J. Thurman   JOURNAL OF CHILD NEUROLOGY

HMGB1 Develops Enhanced Proinflammatory Activity by Binding to Cytokines

(2014) Y. Sha et al.   JOURNAL OF IMMUNOLOGY

Epilepsy Related to Traumatic Brain Injury

(2014) Asla Pitkänen et al.   Neurotherapeutics

Research advances in basic mechanisms of seizures and antiepileptic drug action

(2014) Władysław Lasoń et al.   Pharmacological Reports

The inflammatory molecules IL-1β and HMGB1 can rapidly enhance focal seizure generation in a brain slice model of temporal lobe epilepsy

(2014) Angela Chiavegato et al.   Frontiers in Cellular Neuroscience

Use of antiepileptics for seizure prophylaxis after traumatic brain injury

(2013) H. Torbic et al.   AMERICAN JOURNAL OF HEALTH-SYSTEM PHARMACY

Disulfide-Containing High Mobility Group Box-1 Promotes N-Methyl-d-Aspartate Receptor Function and Excitotoxicity by Activating Toll-Like Receptor 4-Dependent Signaling in Hippocampal Neurons

(2013) Silvia Balosso et al.   ANTIOXIDANTS & REDOX SIGNALING

Novel frontiers in epilepsy treatments: preventing epileptogenesis by targeting inflammation

(2013) Raimondo D’Ambrosio et al.   Expert Review of Neurotherapeutics

The Interleukin-1 Family: Back to the Future

(2013) Cecilia Garlanda et al.   IMMUNITY

The many faces of HMGB1: molecular structure-functional activity in inflammation, apoptosis, and chemotaxis

(2013) Huan Yang et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Acute and chronic traumatic encephalopathies: pathogenesis and biomarkers

(2013) Steven T. DeKosky et al.   Nature Reviews Neurology

Mechanisms of epileptogenesis: a convergence on neural circuit dysfunction

(2013) Ethan M. Goldberg et al.   NATURE REVIEWS NEUROSCIENCE

Receptor for Advanced Glycation Endproducts is upregulated in temporal lobe epilepsy and contributes to experimental seizures

(2013) Valentina Iori et al.   NEUROBIOLOGY OF DISEASE

Long-Term Upregulation of Inflammation and Suppression of Cell Proliferation in the Brain of Adult Rats Exposed to Traumatic Brain Injury Using the Controlled Cortical Impact Model

(2013) Sandra A. Acosta et al.   PLoS One

Neural circuit mechanisms of post–traumatic epilepsy

(2013) Robert F. Hunt et al.   Frontiers in Cellular Neuroscience

Mild passive focal cooling prevents epileptic seizures after head injury in rats

(2012) Raimondo D'Ambrosio et al.   ANNALS OF NEUROLOGY

Long-lasting pro-ictogenic effects induced in vivo by rat brain exposure to serum albumin in the absence of concomitant pathology

(2012) Federica Frigerio et al.   EPILEPSIA

Blood-brain barrier dysfunction, TGFβ signaling, and astrocyte dysfunction in epilepsy

(2012) Uwe Heinemann et al.   GLIA

Interleukin-1 participates in the classical and alternative activation of microglia/macrophages after spinal cord injury

(2012) Atsushi Sato et al.   Journal of Neuroinflammation

Novel role of PKR in inflammasome activation and HMGB1 release

(2012) Ben Lu et al.   NATURE

HMGB1: A multifunctional alarmin driving autoimmune and inflammatory disease

(2012) Helena Erlandsson Harris et al.   Nature Reviews Rheumatology

The Neuropathology and Neurobiology of Traumatic Brain Injury

(2012) Kaj Blennow et al.   NEURON

An overview of the basic science of concussion and subconcussion: where we are and where we are going

(2012) Matthew L. Dashnaw et al.   Neurosurgical Focus

Inflammation in epilepsy: Clinical observations

(2011) Eleonora Aronica et al.   EPILEPSIA

Neutralization of interleukin-1β reduces cerebral edema and tissue loss and improves late cognitive outcome following traumatic brain injury in mice

(2011) Fredrik Clausen et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Essential role of high-mobility group box proteins in nucleic acid-mediated innate immune responses

(2011) H. Yanai et al.   JOURNAL OF INTERNAL MEDICINE

Development of Post-Traumatic Epilepsy after Controlled Cortical Impact and Lateral Fluid-Percussion-Induced Brain Injury in the Mouse

(2011) Tamuna Bolkvadze et al.   JOURNAL OF NEUROTRAUMA

Targets for preventing epilepsy following cortical injury

(2011) Huifang Li et al.   NEUROSCIENCE LETTERS

Inflammation and prevention of epileptogenesis

(2011) Teresa Ravizza et al.   NEUROSCIENCE LETTERS

Anti-epileptogenesis in rodent post-traumatic epilepsy models

(2011) Asla Pitkänen et al.   NEUROSCIENCE LETTERS

Blood–Brain Barrier Pathophysiology in Traumatic Brain Injury

(2011) Adam Chodobski et al.   Translational Stroke Research

High-Mobility Group Box 1, Oxidative Stress, and Disease

(2010) Daolin Tang et al.   ANTIOXIDANTS & REDOX SIGNALING

HMGB proteins: Interactions with DNA and chromatin

(2010) Michal Štros   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Trauma as a Cause of Epilepsy in Childhood

(2010) Bryan Jennett   DEVELOPMENTAL MEDICINE AND CHILD NEUROLOGY

Association of the severity of cortical damage with the occurrence of spontaneous seizures and hyperexcitability in an animal model of posttraumatic epilepsy

(2010) Irina Kharatishvili et al.   EPILEPSY RESEARCH

Post-traumatic seizure susceptibility is attenuated by hypothermia therapy

(2010) Coleen M. Atkins et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Important aspects of Toll-like receptors, ligands and their signaling pathways

(2010) Z. L. Chang   INFLAMMATION RESEARCH

Role of CCL2 (MCP-1) in Traumatic Brain Injury (TBI): Evidence from Severe TBI Patients and CCL2−/− Mice

(2010) Bridgette D Semple et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Epileptogenesis Provoked by Prolonged Experimental Febrile Seizures: Mechanisms and Biomarkers

(2010) C. M. Dube et al.   JOURNAL OF NEUROSCIENCE

Spontaneous Epileptiform Activity in Rat Neocortex after Controlled Cortical Impact Injury

(2010) Lie Yang et al.   JOURNAL OF NEUROTRAUMA

Toll-like receptor 4 and high-mobility group box-1 are involved in ictogenesis and can be targeted to reduce seizures

(2010) Mattia Maroso et al.   NATURE MEDICINE

Blood–brain barrier breakdown as a therapeutic target in traumatic brain injury

(2010) Dan Shlosberg et al.   Nature Reviews Neurology

High mobility group box 1 potentiates the pro-inflammatory effects of interleukin-1β in osteoarthritic synoviocytes

(2010) Isabel García-Arnandis et al.   ARTHRITIS RESEARCH & THERAPY

Blood Monocytes: Development, Heterogeneity, and Relationship with Dendritic Cells

(2009) Cedric Auffray et al.   Annual Review of Immunology

The dynamics of HMG protein–chromatin interactions in living cellsThis paper is one of a selection of papers published in this Special Issue, entitled CSBMCB’s 51st Annual Meeting – Epigenetics and Chromatin Dynamics, and has undergone the Journal’s usual peer review process.

(2009) Gabi Gerlitz et al.   Biochemistry and Cell Biology

What has inflammation to do with traumatic brain injury?

(2009) David Cederberg et al.   CHILDS NERVOUS SYSTEM

Mechanisms of action, physiological effects, and complications of hypothermia

(2009) Kees H. Polderman   CRITICAL CARE MEDICINE

Preventing and treating posttraumatic seizures: The human experience

(2009) Nancy R. Temkin   EPILEPSIA

Innate but not adaptive immune responses contribute to behavioral seizures following viral infection

(2009) Nikki J. Kirkman et al.   EPILEPSIA

A potential model of pediatric posttraumatic epilepsy

(2009) K.D. Statler et al.   EPILEPSY RESEARCH

Blood–brain barrier breakdown-inducing astrocytic transformation: Novel targets for the prevention of epilepsy

(2009) Alon Friedman et al.   EPILEPSY RESEARCH

Contributions of peripheral inflammation to seizure susceptibility: Cytokines and brain excitability

(2009) Kiarash Riazi et al.   EPILEPSY RESEARCH

Mitochondria, oxidative stress, and temporal lobe epilepsy

(2009) Simon Waldbaum et al.   EPILEPSY RESEARCH

Neutralization of interleukin-1β modifies the inflammatory response and improves histological and cognitive outcome following traumatic brain injury in mice

(2009) Fredrik Clausen et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Transcriptome Profiling Reveals TGF-  Signaling Involvement in Epileptogenesis

(2009) L. P. Cacheaux et al.   JOURNAL OF NEUROSCIENCE

Astrocytic Dysfunction in Epileptogenesis: Consequence of Altered Potassium and Glutamate Homeostasis?

(2009) Y. David et al.   JOURNAL OF NEUROSCIENCE

In Situ Detection of Inflammatory Mediators in Post Mortem Human Brain Tissue after Traumatic Injury

(2009) Tony Frugier et al.   JOURNAL OF NEUROTRAUMA

The “window of susceptibility” for inflammation in the immature central nervous system is characterized by a leaky blood–brain barrier and the local expression of inflammatory chemokines

(2009) Lucia Schoderboeck et al.   NEUROBIOLOGY OF DISEASE

Viral-like brain inflammation during development causes increased seizure susceptibility in adult rats

(2009) M.A. Galic et al.   NEUROBIOLOGY OF DISEASE

Molecular and functional interactions between tumor necrosis factor-alpha receptors and the glutamatergic system in the mouse hippocampus: Implications for seizure susceptibility

(2009) S. Balosso et al.   NEUROSCIENCE

The role of cytokines in the pathophysiology of epilepsy

(2008) Annamaria Vezzani et al.   BRAIN BEHAVIOR AND IMMUNITY

Toll-like receptors in neurodegeneration

(2008) Eitan Okun et al.   BRAIN RESEARCH REVIEWS

LPS/TLR4 signal transduction pathway

(2008) Yong-Chen Lu et al.   CYTOKINE

Neonatal inflammation produces selective behavioural deficits and alters N-methyl-d-aspartate receptor subunit mRNA in the adult rat brain

(2008) E.-M. Harré et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Systemic inflammation exacerbates behavioral and histopathological consequences of isolated traumatic brain injury in rats

(2008) Akira Utagawa et al.   EXPERIMENTAL NEUROLOGY

Posttraumatic epilepsy after controlled cortical impact injury in mice

(2008) Robert F. Hunt et al.   EXPERIMENTAL NEUROLOGY

Suppression of acute proinflammatory cytokine and chemokine upregulation by post-injury administration of a novel small molecule improves long-term neurologic outcome in a mouse model of traumatic brain injury

(2008) Eric Lloyd et al.   Journal of Neuroinflammation

Postnatal Inflammation Increases Seizure Susceptibility in Adult Rats

(2008) M. A. Galic et al.   JOURNAL OF NEUROSCIENCE

Moderate and severe traumatic brain injury in adults

(2008) Andrew IR Maas et al.   LANCET NEUROLOGY

Astrocytes in the Epileptic Brain

(2008) Jonathon Wetherington et al.   NEURON

Multiplex Assessment of Serum Biomarker Concentrations in Well-Appearing Children With Inflicted Traumatic Brain Injury

(2008) Rachel P Berger et al.   PEDIATRIC RESEARCH

Acute, regional inflammatory response after traumatic brain injury: Implications for cellular therapy

(2008) Matthew T. Harting et al.   SURGERY

Blood-brain barrier disruption in post-traumatic epilepsy

(2007) O Tomkins et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY