Celecoxib Exerts Neuroprotective Effects in β-Amyloid-Treated SH-SY5Y Cells Through the Regulation of Heme Oxygenase-1: Novel Insights for an Old Drug

LncRNA17A regulates autophagy and apoptosis of SH-SY5Y cell line as an in vitro model for Alzheimer’s disease

(2019) Xinhua Wang et al.   BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY

Curcumin and Heme Oxygenase: Neuroprotection and Beyond

(2019) Emanuela Mhillaj et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Combined Treatment with Three Natural Antioxidants Enhances Neuroprotection in a SH-SY5Y 3D Culture Model

(2019) Marrazzo et al.   Antioxidants

Effect of atorvastatin on Aβ 1–42 ‐induced alteration of SESN2, SIRT1, LC3II and TPP1 protein expressions in neuronal cell cultures

(2019) Hande Çelik et al.   JOURNAL OF PHARMACY AND PHARMACOLOGY

Celecoxib Prevents Cognitive Impairment and Neuroinflammation in Soluble Amyloid β-treated Rats

(2018) Emanuela Mhillaj et al.   NEUROSCIENCE

Celecoxib exerts protective effects in the vascular endothelium via COX-2-independent activation of AMPK-CREB-Nrf2 signalling

(2018) Fahad Al-Rashed et al.   Scientific Reports

Heme Oxygenase 1 in the Nervous System: Does It Favor Neuronal Cell Survival or Induce Neurodegeneration?

(2018) Mariapaola Nitti et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Oxidative and Nitrosative Modifications of Biliverdin Reductase-A in the Brain of Subjects with Alzheimer's Disease and Amnestic Mild Cognitive Impairment

(2018) Eugenio Barone et al.   JOURNAL OF ALZHEIMERS DISEASE

HO-1/BVR-A System Analysis in Plasma from Probable Alzheimer's Disease and Mild Cognitive Impairment Subjects: A Potential Biochemical Marker for the Prediction of the Disease

(2018) Fabio Di Domenico et al.   JOURNAL OF ALZHEIMERS DISEASE

Carbon monoxide attenuates amyloidogenesis via down-regulation of NF-κB-mediated BACE1 gene expression

(2018) Hyo Jeong Kim et al.   AGING CELL

Farrerol attenuates β-amyloid-induced oxidative stress and inflammation through Nrf2/Keap1 pathway in a microglia cell line

(2018) Bei Cui et al.   BIOMEDICINE & PHARMACOTHERAPY

Ferulic Acid Improves Cognitive Skills Through the Activation of the Heme Oxygenase System in the Rat

(2017) Emanuela Mhillaj et al.   MOLECULAR NEUROBIOLOGY

Resveratrol Attenuates the Cytotoxicity Induced by Amyloid-β1–42 in PC12 Cells by Upregulating Heme Oxygenase-1 via the PI3K/Akt/Nrf2 Pathway

(2017) Yang Hui et al.   NEUROCHEMICAL RESEARCH

Bilirubin and brain: A pharmacological approach

(2017) Cesare Mancuso   NEUROPHARMACOLOGY

Heme oxygenase-1 derived carbon monoxide suppresses Aβ1–42 toxicity in astrocytes

(2017) Nishani T Hettiarachchi et al.   Cell Death & Disease

Bacteria Meet Graphene: Modulation of Graphene Oxide Nanosheet Interaction with Human Pathogens for Effective Antimicrobial Therapy

(2017) Valentina Palmieri et al.   ACS Biomaterials-Science & Engineering

Bacteria Meet Graphene: Modulation of Graphene Oxide Nanosheet Interaction with Human Pathogens for Effective Antimicrobial Therapy

(2017) Valentina Palmieri et al.   ACS Biomaterials Science & Engineering

The amyloid hypothesis of Alzheimer's disease at 25 years

(2016) Dennis J Selkoe et al.   EMBO Molecular Medicine

Inhibition of beta-amyloid-induced neurotoxicity by pinocembrin through Nrf2/HO-1 pathway in SH-SY5Y cells

(2016) Yumin Wang et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Ferulic Acid Regulates the Nrf2/Heme Oxygenase-1 System and Counteracts Trimethyltin-Induced Neuronal Damage in the Human Neuroblastoma Cell Line SH-SY5Y

(2016) Stefania Catino et al.   Frontiers in Pharmacology

Biophysical Comparison of Soluble Amyloid-β(1–42) Protofibrils, Oligomers, and Protofilaments

(2015) Michael R. Nichols et al.   BIOCHEMISTRY

Non-Steroidal Anti-Inflammatory Drugs as a Treatment for Alzheimer’s Disease: A Systematic Review and Meta-Analysis of Treatment Effect

(2015) Marina Miguel-Álvarez et al.   DRUGS & AGING

Rosmarinic acid up-regulates the noise-activated Nrf2/HO-1 pathway and protects against noise-induced injury in rat cochlea

(2015) A.R. Fetoni et al.   FREE RADICAL BIOLOGY AND MEDICINE

Nrf2—a therapeutic target for the treatment of neurodegenerative diseases

(2015) Delinda A. Johnson et al.   FREE RADICAL BIOLOGY AND MEDICINE

Memantine prevents memory consolidation failure induced by soluble beta amyloid in rats

(2014) Paolo Tucci et al.   Frontiers in Behavioral Neuroscience

Deleterious effects of soluble amyloid-β oligomers on multiple steps of synaptic vesicle trafficking

(2013) Joohyun Park et al.   NEUROBIOLOGY OF DISEASE

Predominant loss of glutamatergic terminal markers in a β-amyloid peptide model of Alzheimer's disease

(2013) Paula M. Canas et al.   NEUROPHARMACOLOGY

Neuroinflammation, Oxidative Stress and the Pathogenesis of Alzheimers Disease

(2012) Paula Agostinho et al.   CURRENT PHARMACEUTICAL DESIGN

Heme oxygenase-1 posttranslational modifications in the brain of subjects with Alzheimer disease and mild cognitive impairment

(2012) Eugenio Barone et al.   FREE RADICAL BIOLOGY AND MEDICINE

Guanosine protects human neuroblastoma SH-SY5Y cells against mitochondrial oxidative stress by inducing heme oxigenase-1 via PI3K/Akt/GSK-3β pathway

(2012) Tharine Dal-Cim et al.   NEUROCHEMISTRY INTERNATIONAL

Direct Antioxidant Properties of Bilirubin and Biliverdin. Is there a Role for Biliverdin Reductase?

(2012) Thomas Jansen et al.   Frontiers in Pharmacology

Extended results of the Alzheimer’s disease anti-inflammatory prevention trial

(2011) John C. Breitner et al.   Alzheimers & Dementia

Biliverdin reductase-A protein levels and activity in the brains of subjects with Alzheimer disease and mild cognitive impairment

(2011) Eugenio Barone et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Aβ Oligomer-Induced Synapse Degeneration in Alzheimer’s Disease

(2011) Kyle C. Wilcox et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Atorvastatin treatment in a dog preclinical model of Alzheimer's disease leads to up-regulation of haem oxygenase-1 and is associated with reduced oxidative stress in brain

(2011) D. Allan Butterfield et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Nature of the Amyloid-β Monomer and the Monomer-Oligomer Equilibrium

(2011) Suman Nag et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Biliverdin reductase-A: a novel drug target for atorvastatin in a dog pre-clinical model of Alzheimer disease

(2011) Eugenio Barone et al.   JOURNAL OF NEUROCHEMISTRY

Celecoxib induces heme oxygenase-1 expression in macrophages and vascular smooth muscle cells via ROS-dependent signaling pathway

(2010) Jang-Shiun Wang et al.   NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY

Are NSAIDs useful to treat Alzheimer’s disease or mild cognitive impairment?

(2010) Imbimbo   Frontiers in Aging Neuroscience

Alzheimer's Disease Anti-Inflammatory Prevention Trial: Design, methods, and baseline results

(2009)   Alzheimers & Dementia

Cognitive Function Over Time in the Alzheimer's Disease Anti-inflammatory Prevention Trial (ADAPT)

(2008)   ARCHIVES OF NEUROLOGY

Redox regulation of cellular stress response by ferulic acid ethyl ester in human dermal fibroblasts: role of vitagenes

(2008) Vittorio Calabrese et al.   CLINICS IN DERMATOLOGY

Carbon monoxide, reactive oxygen signaling, and oxidative stress

(2008) Claude A. Piantadosi   FREE RADICAL BIOLOGY AND MEDICINE

Linking Calcium to Aβ and Alzheimer's Disease

(2008) Kim N. Green et al.   NEURON