Infliximab reduces peripheral inflammation, neuroinflammation, and extracellular GABA in the cerebellum and improves learning and motor coordination in rats with hepatic encephalopathy

Neuroinflammation in Alzheimer's Disease and Mild Cognitive Impairment: A Field in Its Infancy

(2017) Edith G. McGeer et al.   JOURNAL OF ALZHEIMERS DISEASE

Imaging of neuroinflammation in Alzheimer's disease, multiple sclerosis and stroke: Recent developments in positron emission tomography

(2016) Bieneke Janssen et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

In vivo administration of extracellular cGMP normalizes TNF-α and membrane expression of AMPA receptors in hippocampus and spatial reference memory but not IL-1β, NMDA receptors in membrane and working memory in hyperammonemic rats

(2016) Andrea Cabrera-Pastor et al.   BRAIN BEHAVIOR AND IMMUNITY

Neuroinflammation increases GABAergic tone and impairs cognitive and motor function in hyperammonemia by increasing GAT-3 membrane expression. Reversal by sulforaphane by promoting M2 polarization of microglia

(2016) Vicente Hernandez-Rabaza et al.   Journal of Neuroinflammation

Hyperammonemia induces glial activation, neuroinflammation and alters neurotransmitter receptors in hippocampus, impairing spatial learning: reversal by sulforaphane

(2016) Vicente Hernández-Rabaza et al.   Journal of Neuroinflammation

18F-DPA-714 PET Imaging for Detecting Neuroinflammation in Rats with Chronic Hepatic Encephalopathy

(2016) Xiang Kong et al.   Theranostics

GR3027 antagonizes GABAA receptor-potentiating neurosteroids and restores spatial learning and motor coordination in rats with chronic hyperammonemia and hepatic encephalopathy

(2015) Maja Johansson et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Systemic lipopolysaccharide administration impairs retrieval of context–object discrimination, but not spatial, memory: Evidence for selective disruption of specific hippocampus-dependent memory functions during acute neuroinflammation

(2015) Jennifer Czerniawski et al.   BRAIN BEHAVIOR AND IMMUNITY

Tumor necrosis factor stimulates expression of CXCL12 in astrocytes

(2015) Jana Blaževski et al.   IMMUNOBIOLOGY

Microglia and neuroprotection

(2015) Zhihong Chen et al.   JOURNAL OF NEUROCHEMISTRY

Sildenafil reduces neuroinflammation and restores spatial learning in rats with hepatic encephalopathy: underlying mechanisms

(2015) Vicente Hernandez-Rabaza et al.   Journal of Neuroinflammation

Early activation of microglia and astrocytes in mouse models of spinocerebellar ataxia type 1

(2015) M. Cvetanovic et al.   NEUROSCIENCE

Acute nicotine treatment attenuates lipopolysaccharide-induced cognitive dysfunction by increasing BDNF expression and inhibiting neuroinflammation in the rat hippocampus

(2015) Penghui Wei et al.   NEUROSCIENCE LETTERS

Targeting TNF: a therapeutic strategy for Alzheimer's disease

(2014) Xin Cheng et al.   DRUG DISCOVERY TODAY

Non invasive blood flow measurement in cerebellum detects minimal hepatic encephalopathy earlier than psychometric tests

(2014) Vicente Felipo   WORLD JOURNAL OF GASTROENTEROLOGY

Pregnenolone Sulfate Restores the Glutamate-Nitric-Oxide-cGMP Pathway and Extracellular GABA in Cerebellum and Learning and Motor Coordination in Hyperammonemic Rats

(2013) Alba Gonzalez-Usano et al.   ACS Chemical Neuroscience

Chronic Administration of Infliximab (TNF-α Inhibitor) Decreases Depression and Anxiety-like Behaviour in Rat Model of Chronic Mild Stress

(2013) Ayşe Karson et al.   BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY

Liver Injury From Tumor Necrosis Factor-α Antagonists: Analysis of Thirty-four Cases

(2013) Marwan Ghabril et al.   Clinical Gastroenterology and Hepatology

Systemic Immune Activation Leads to Neuroinflammation and Sickness Behavior in Mice

(2013) Steven Biesmans et al.   MEDIATORS OF INFLAMMATION

Hepatic encephalopathy: effects of liver failure on brain function

(2013) Vicente Felipo   NATURE REVIEWS NEUROSCIENCE

Disease activity and cognition in rheumatoid arthritis: an open label pilot study

(2012) Graham Raftery et al.   ARTHRITIS RESEARCH & THERAPY

p38 MAP kinase is a therapeutic target for hepatic encephalopathy in rats with portacaval shunts

(2011) A. Agusti et al.   GUT

Contribution of hyperammonemia and inflammatory factors to cognitive impairment in minimal hepatic encephalopathy

(2011) Vicente Felipo et al.   METABOLIC BRAIN DISEASE

Hyperammonemia Induces Neuroinflammation That Contributes to Cognitive Impairment in Rats With Hepatic Encephalopathy

(2010) Regina Rodrigo et al.   GASTROENTEROLOGY

Reversibility of hepatic encephalopathy after liver transplantation

(2010) Dileep K. Atluri et al.   METABOLIC BRAIN DISEASE

Developmental exposure to polychlorinated biphenyls 52, 138 or 180 affects differentially learning or motor coordination in adult rats. mechanisms involved

(2010) J. Boix et al.   NEUROSCIENCE

Postoperative cognitive deficits and neuroinflammation in the hippocampus triggered by surgical trauma are exacerbated in aged rats

(2010) Xue-Zhao Cao et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Everyday Cognitive Failure in Sarcoidosis: The Prevalence and the Effect of Anti-TNF-α Treatment

(2010) Marjon D. Elfferich et al.   RESPIRATION

Neuroinflammation and Cognitive Aging

(2010) Raymond L. Ownby   Current Psychiatry Reports

Hyperammonemia Increases GABAergic Tone in the Cerebellum but Decreases It in the Rat Cortex

(2009) Omar Cauli et al.   GASTROENTEROLOGY

IL-6 and IL-18 in Blood May Discriminate Cirrhotic Patients With and Without Minimal Hepatic Encephalopathy

(2009) Carmina Montoliu et al.   JOURNAL OF CLINICAL GASTROENTEROLOGY

Cerebral Microglia Recruit Monocytes into the Brain in Response to Tumor Necrosis Factor  Signaling during Peripheral Organ Inflammation

(2009) C. D'Mello et al.   JOURNAL OF NEUROSCIENCE

Experimental models of hepatic encephalopathy: ISHEN guidelines

(2009) Roger F. Butterworth et al.   LIVER INTERNATIONAL

Rapid cognitive improvement in Alzheimer's disease following perispinal etanercept administration

(2008) Edward L Tobinick et al.   Journal of Neuroinflammation

Immune-To-Brain Signaling: How Important are the Blood–Brain Barrier-independent Pathways?

(2008) Ning Quan   MOLECULAR NEUROBIOLOGY