Atorvastatin Prevents Early Oxidative Events and Modulates Inflammatory Mediators in the Striatum Following Intranasal 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) Administration in Rats

Atorvastatin and Fluoxetine Prevent Oxidative Stress and Mitochondrial Dysfunction Evoked by Glutamate Toxicity in Hippocampal Slices

(2016) Fabiana K. Ludka et al.   MOLECULAR NEUROBIOLOGY

Harnessing the trophic and modulatory potential of statins in a dopaminergic cell line

(2016) Mathieu Schmitt et al.   SYNAPSE

Neurocytoprotective Effects of Aliphatic Hydroxamates from Lovastatin, a Secondary Metabolite from Monascus-Fermented Red Mold Rice, in 6-Hydroxydopamine (6-OHDA)-Treated Nerve Growth Factor (NGF)-Differentiated PC12 Cells

(2015) Chien-Min Lin et al.   ACS Chemical Neuroscience

Atorvastatin Prevents Cognitive Deficits Induced by Intracerebroventricular Amyloid-β1–40 Administration in Mice: Involvement of Glutamatergic and Antioxidant Systems

(2015) Wagner C. Martins et al.   NEUROTOXICITY RESEARCH

Atorvastatin improves cognitive, emotional and motor impairments induced by intranasal 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) administration in rats, an experimental model of Parkinson's disease

(2013) Adalberto A. Castro et al.   BRAIN RESEARCH

Parkinson disease: from pathology to molecular disease mechanisms

(2013) David T. Dexter et al.   FREE RADICAL BIOLOGY AND MEDICINE

Atorvastatin prevents cell damage via modulation of oxidative stress, glutamate uptake and glutamine synthetase activity in hippocampal slices subjected to oxygen/glucose deprivation

(2013) Samuel Vandresen-Filho et al.   NEUROCHEMISTRY INTERNATIONAL

MALDI Mass Spectrometry Imaging of 1-Methyl-4-phenylpyridinium (MPP+) in Mouse Brain

(2013) Hanane Kadar et al.   NEUROTOXICITY RESEARCH

Prospective Study of Statin Use and Risk of Parkinson Disease

(2012) Xiang Gao   ARCHIVES OF NEUROLOGY

Neuroprotective effects of agmatine in mice infused with a single intranasal administration of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)

(2012) Filipe C. Matheus et al.   BEHAVIOURAL BRAIN RESEARCH

Lithium and valproate prevent olfactory discrimination and short-term memory impairments in the intranasal 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) rat model of Parkinson's disease

(2012) Adalberto A. Castro et al.   BEHAVIOURAL BRAIN RESEARCH

Neuroprotective potential of atorvastatin and simvastatin (HMG-CoA reductase inhibitors) against 6-hydroxydopamine (6-OHDA) induced Parkinson-like symptoms

(2012) Anil Kumar et al.   BRAIN RESEARCH

Probucol and atorvastatin in combination protect rat brains in MCAO model: Upregulating Peroxiredoxin2, Foxo3a and Nrf2 expression

(2012) Yuanyuan Du et al.   NEUROSCIENCE LETTERS

The Intranasal Administration of 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine (MPTP): A New Rodent Model to Test Palliative and Neuroprotective Agents for Parkinson's disease

(2011) Rui D. S. Prediger et al.   CURRENT PHARMACEUTICAL DESIGN

Atorvastatin prevents hippocampal cell death, neuroinflammation and oxidative stress following amyloid-β1–40 administration in mice: Evidence for dissociation between cognitive deficits and neuronal damage

(2010) Tetsadê C.B. Piermartiri et al.   EXPERIMENTAL NEUROLOGY

Statins: Multiple neuroprotective mechanisms in neurodegenerative diseases

(2010) Qing Wang et al.   EXPERIMENTAL NEUROLOGY

Proanthocyanidin-rich fraction from Croton celtidifolius Baill confers neuroprotection in the intranasal 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine rat model of Parkinson’s disease

(2010) Eduardo L. G. Moreira et al.   JOURNAL OF NEURAL TRANSMISSION

Risk is in the Air

(2009) Rui D. S. Prediger et al.   Annals of the New York Academy of Sciences

MPTP lesion causes neuroinflammation and deficits in object recognition in Wistar rats.

(2009) Wen-Fu Wang et al.   BEHAVIORAL NEUROSCIENCE

Involvement of NMDA receptors in both MPTP-induced neuroinflammation and deficits in episodic-like memory in Wistar rats

(2009) An-Li Wang et al.   BEHAVIOURAL BRAIN RESEARCH

Simvastatin Inhibits the Activation of p21ras and Prevents the Loss of Dopaminergic Neurons in a Mouse Model of Parkinson's Disease

(2009) A. Ghosh et al.   JOURNAL OF NEUROSCIENCE

Atorvastatin Prevents Hippocampal Cell Death due to Quinolinic Acid-Induced Seizures in Mice by Increasing Akt Phosphorylation and Glutamate Uptake

(2009) Tetsadê C. B. Piermartiri et al.   NEUROTOXICITY RESEARCH

Single Intranasal Administration of 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine in C57BL/6 Mice Models Early Preclinical Phase of Parkinson’s Disease

(2009) Rui D. S. Prediger et al.   NEUROTOXICITY RESEARCH

Simvastatin prevents the inflammatory process and the dopaminergic degeneration induced by the intranigral injection of lipopolysaccharide

(2008) María del Carmen Hernández-Romero et al.   JOURNAL OF NEUROCHEMISTRY

Disease-modifying drugs and Parkinson's disease

(2007) Hervé Allain et al.   PROGRESS IN NEUROBIOLOGY