Genome Mining for Antimicrobial Compounds in Wild Marine Animals-Associated Enterococci

Bioinformatic prospecting and phylogenetic analysis reveals 94 undescribed circular bacteriocins and key motifs

(2020) Ben Vezina et al.   BMC MICROBIOLOGY

The efficacy of eribulin mesylate for patients with cutaneous angiosarcoma previously treated with taxane: a multicentre prospective observational study

(2020) Y. Fujisawa et al.   BRITISH JOURNAL OF DERMATOLOGY

Discovery of an Isothiazolinone-Containing Antitubercular Natural Product Levesquamide

(2020) Libang Liang et al.   JOURNAL OF ORGANIC CHEMISTRY

In Silico Analysis Highlights the Diversity and Novelty of Circular Bacteriocins in Sequenced Microbial Genomes

(2020) Bingyue Xin et al.   mSystems

Enterococci from wild Magellanic Penguins (Spheniscus magellanicus) as an indicator of marine ecosystem health and human impact

(2020) Janira Prichula et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

A Review of Terpenes from Marine-Derived Fungi: 2015–2019

(2020) Minghua Jiang et al.   Marine Drugs

The Revaluation of Plant-Derived Terpenes to Fight Antibiotic-Resistant Infections

(2020) Floriana Cappiello et al.   Antibiotics-Basel

Overview of Global Trends in Classification, Methods of Preparation and Application of Bacteriocins

(2020) Maria Zimina et al.   Antibiotics-Basel

Expression in eukaryotic cells and purification of synthetic gene encoding enterocin P: a bacteriocin with broad antimicrobial spectrum

(2019) Abbas Tanhaeian et al.   AMB Express

Novel bioactive natural products from bacteria via bioprospecting, genome mining and metabolic engineering

(2019) Olga N. Sekurova et al.   Microbial Biotechnology

Detecting and prioritizing biosynthetic gene clusters for bioactive compounds in bacteria and fungi

(2019) Phuong Nguyen Tran et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Insights into Red Sea Brine Pool Specialized Metabolism Gene Clusters Encoding Potential Metabolites for Biotechnological Applications and Extremophile Survival

(2019) Laila Ziko et al.   Marine Drugs

Interactive Tree Of Life (iTOL) v4: recent updates and new developments

(2019) Ivica Letunic et al.   NUCLEIC ACIDS RESEARCH

antiSMASH 5.0: updates to the secondary metabolite genome mining pipeline

(2019) Kai Blin et al.   NUCLEIC ACIDS RESEARCH

Antibacterial Activity of Terpenes and Terpenoids Present in Essential Oils

(2019) Aline Cristina Guimarães et al.   MOLECULES

Discovery pipelines for marine resources: an ocean of opportunity for biotechnology?

(2019) D. Smith et al.   WORLD JOURNAL OF MICROBIOLOGY & BIOTECHNOLOGY

Survey of Biosynthetic Gene Clusters from Sequenced Myxobacteria Reveals Unexplored Biosynthetic Potential

(2019) Katherine Gregory et al.   Microorganisms

Loci Encoding Compounds Potentially Active against Drug-Resistant Pathogens amidst a Decreasing Pool of Novel Antibiotics

(2019) Joseph Basalla et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Expression of Enterocin-P in HEK Platform: Evaluation of Its Cytotoxic Effects on Cancer Cell Lines and Its Potency to Interact with Cell-Surface Glycosaminoglycan by Molecular Modeling

(2019) Zana Pirkhezranian et al.   International Journal of Peptide Research and Therapeutics

Marine Pharmacology in 2014–2015: Marine Compounds with Antibacterial, Antidiabetic, Antifungal, Anti-Inflammatory, Antiprotozoal, Antituberculosis, Antiviral, and Anthelmintic Activities; Affecting the Immune and Nervous Systems, and Other Miscellaneous Mechanisms of Action

(2019) Alejandro M. S. Mayer et al.   Marine Drugs

Cloning, overexpression, purification of bacteriocin enterocin-B and structural analysis, interaction determination of enterocin-A, B against pathogenic bacteria and human cancer cells

(2018) Dasari Ankaiah et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Approaches for enhancing in situ detection of enterocin genes in thermized milk, and selective isolation of enterocin-producing Enterococcus faecium from Baird-Parker agar

(2018) Elpiniki Vandera et al.   INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY

Characterization of semipurified enterocins produced by Enterococcus faecium strains isolated from raw camel milk

(2018) Rita Rahmeh et al.   JOURNAL OF DAIRY SCIENCE

Discovery, research, and development of new antibiotics: the WHO priority list of antibiotic-resistant bacteria and tuberculosis

(2018) Evelina Tacconelli et al.   LANCET INFECTIOUS DISEASES

BAGEL4: a user-friendly web server to thoroughly mine RiPPs and bacteriocins

(2018) Auke J van Heel et al.   NUCLEIC ACIDS RESEARCH

OUP accepted manuscript

(2018)   PAIN MEDICINE

Synthesis, antimicrobial activity and conformational analysis of the class IIa bacteriocin pediocin PA-1 and analogs thereof

(2018) François Bédard et al.   Scientific Reports

Recent Progress in the Chemical Synthesis of Class II and S-Glycosylated Bacteriocins

(2018) François Bédard et al.   Frontiers in Microbiology

Lactic Acid Bacteria in Finfish—An Update

(2018) Einar Ringø et al.   Frontiers in Microbiology

The Genus Enterococcus: Between Probiotic Potential and Safety Concerns—An Update

(2018) Hasna Hanchi et al.   Frontiers in Microbiology

Anti–Influenza Activity of Enterocin B In vitro and Protective Effect of Bacteriocinogenic Enterococcal Probiotic Strain on Influenza Infection in Mouse Model

(2018) E. I. Ermolenko et al.   Probiotics and Antimicrobial Proteins

Natural Products from Mammalian Gut Microbiota

(2018) Leli Wang et al.   TRENDS IN BIOTECHNOLOGY

Using natural products for drug discovery: the impact of the genomics era

(2017) Mingzi M Zhang et al.   Expert Opinion on Drug Discovery

The safe enterocin DD14 is a leaderless two-peptide bacteriocin with anti-Clostridium perfringens activity

(2017) Delphine L. Caly et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

SMS: Smart Model Selection in PhyML

(2017) Vincent Lefort et al.   MOLECULAR BIOLOGY AND EVOLUTION

The drug-resistant bacteria that pose the greatest health threats

(2017) Cassandra Willyard   NATURE

RefSeq: an update on prokaryotic genome annotation and curation

(2017) Daniel H Haft et al.   NUCLEIC ACIDS RESEARCH

Marine microbiome as source of natural products

(2017) Fernando de la Calle   Microbial Biotechnology

A novel bacteriocin from Enterococcus faecalis 478 exhibits a potent activity against vancomycin-resistant enterococci

(2017) Uraporn Phumisantiphong et al.   PLoS One

Bacteriocins of lactic acid bacteria: extending the family

(2016) Patricia Alvarez-Sieiro et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Evaluation of marine bacteriocinogenic enterococci strains with inhibitory activity against fish-pathogenic Gram-negative bacteria

(2016) H Ghomrassi et al.   DISEASES OF AQUATIC ORGANISMS

A genomic view of food-related and probiotic Enterococcus strains

(2016) Julieta Bonacina et al.   DNA RESEARCH

Host-derived probiotics Enterococcus casseliflavus improves resistance against Streptococcus iniae infection in rainbow trout (Oncorhynchus mykiss) via immunomodulation

(2016) Reza Safari et al.   FISH & SHELLFISH IMMUNOLOGY

A decade of genomic history for healthcare-associatedEnterococcus faeciumin the United Kingdom and Ireland

(2016) Kathy E. Raven et al.   GENOME RESEARCH

Screening of the Enterocin-Encoding Genes and Antimicrobial Activity in Enterococcus Species

(2016) Mayara Baptistucci Ogaki et al.   JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY

Resistance to antimicrobial agents among enterococci isolated from fecal samples of wild marine species in the southern coast of Brazil

(2016) Janira Prichula et al.   MARINE POLLUTION BULLETIN

Discovery of MRSA active antibiotics using primary sequence from the human microbiome

(2016) John Chu et al.   Nature Chemical Biology

CARD 2017: expansion and model-centric curation of the comprehensive antibiotic resistance database

(2016) Baofeng Jia et al.   NUCLEIC ACIDS RESEARCH

Genome-based characterization of hospital-adapted Enterococcus faecalis lineages

(2016) Kathy E. Raven et al.   Nature Microbiology

Antibiotic drug discovery

(2016) Wolfgang Wohlleben et al.   Microbial Biotechnology

JSpeciesWS: a web server for prokaryotic species circumscription based on pairwise genome comparison

(2015) Michael Richter et al.   BIOINFORMATICS

The Sactibiotic Subclass of Bacteriocins: An Update

(2015) Harsh Mathur et al.   CURRENT PROTEIN & PEPTIDE SCIENCE

Emerging Concepts Promising New Horizons for Marine Biodiscovery and Synthetic Biology

(2015) F. Reen et al.   Marine Drugs

Protective Effect of Diphlorethohydroxycarmalol against Ultraviolet B Radiation-Induced DNA Damage by Inducing the Nucleotide Excision Repair System in HaCaT Human Keratinocytes

(2015) Mei Piao et al.   Marine Drugs

The I-TASSER Suite: protein structure and function prediction

(2015) Jianyi Yang et al.   NATURE METHODS

GUIDANCE2: accurate detection of unreliable alignment regions accounting for the uncertainty of multiple parameters

(2015) Itamar Sela et al.   NUCLEIC ACIDS RESEARCH

Small molecules from the human microbiota

(2015) M. S. Donia et al.   SCIENCE

Antimicrobial resistance and virulence factor gene profiles of Enterococcus spp. isolates from wild Arctocephalus australis (South American fur seal) and Arctocephalus tropicalis (Subantarctic fur seal)

(2015) Naiara Aguiar Santestevan et al.   WORLD JOURNAL OF MICROBIOLOGY & BIOTECHNOLOGY

Forazoline A: Marine-Derived Polyketide with Antifungal In Vivo Efficacy

(2014) Thomas P. Wyche et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Lipid-lowering effects of farnesylquinone and related analogues from the marine-derived Streptomyces nitrosporeus

(2014) Dong Liu et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

A Systematic Analysis of Biosynthetic Gene Clusters in the Human Microbiome Reveals a Common Family of Antibiotics

(2014) Mohamed S. Donia et al.   CELL

The effect of probioticEnterococcus gallinarumL-1 on the innate immune parameters of outstanding species to marine aquaculture

(2014) Lorena Román et al.   JOURNAL OF APPLIED ANIMAL RESEARCH

Real-Time Whole-Genome Sequencing for Routine Typing, Surveillance, and Outbreak Detection of Verotoxigenic Escherichia coli

(2014) K. G. Joensen et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Penicillipyrones A and B, Meroterpenoids from a Marine-Derived Penicillium sp. Fungus

(2014) Lijuan Liao et al.   JOURNAL OF NATURAL PRODUCTS

Determination of the mode of action of enterolysin A, produced byEnterococcus faecalisB9510

(2013) H. Khan et al.   JOURNAL OF APPLIED MICROBIOLOGY

Microbial characterization of probiotics-Advisory report of the Working Group “8651 Probiotics” of the Belgian Superior Health Council (SHC)

(2013) Geert Huys et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Emergence of Epidemic Multidrug-Resistant Enterococcus faecium from Animal and Commensal Strains

(2013) F. Lebreton et al.   mBio

Structure, Function, and Biology of the Enterococcus faecalis Cytolysin

(2013) Daria Van Tyne et al.   Toxins

Identification of acquired antimicrobial resistance genes

(2012) E. Zankari et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Bacteriocins — a viable alternative to antibiotics?

(2012) Paul D. Cotter et al.   NATURE REVIEWS MICROBIOLOGY

Comparative Genomics of Enterococci: Variation in Enterococcus faecalis, Clade Structure in E. faecium, and Defining Characteristics of E. gallinarum and E. casseliflavus

(2012) K. L. Palmer et al.   mBio

Genome-Based Studies of Marine Microorganisms to Maximize the Diversity of Natural Products Discovery for Medical Treatments

(2011) Xin-Qing Zhao   Evidence-based Complementary and Alternative Medicine

D³ Data-Driven Documents

(2011) M. Bostock et al.   IEEE TRANSACTIONS ON VISUALIZATION AND COMPUTER GRAPHICS

Bacteriocin as Weapons in the Marine Animal-Associated Bacteria Warfare: Inventory and Potential Applications as an Aquaculture Probiotic

(2010) Florie Desriac et al.   Marine Drugs

New Algorithms and Methods to Estimate Maximum-Likelihood Phylogenies: Assessing the Performance of PhyML 3.0

(2010) Stéphane Guindon et al.   SYSTEMATIC BIOLOGY

The Abyssomicin C family as in vitro inhibitors of Mycobacterium tuberculosis

(2010) Joel S. Freundlich et al.   TUBERCULOSIS

Bioactive Compounds from Marine Bacteria and Fungi

(2010) Abdessamad Debbab et al.   Microbial Biotechnology

Shifting the genomic gold standard for the prokaryotic species definition

(2009) Michael Richter et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Defined salt formulations for the growth of Salinispora tropica strain NPS21184 and the production of salinosporamide A (NPI-0052) and related analogs

(2008) Ginger Tsueng et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

I-TASSER server for protein 3D structure prediction

(2008) Yang Zhang   BMC BIOINFORMATICS