Survey of Biosynthetic Gene Clusters from Sequenced Myxobacteria Reveals Unexplored Biosynthetic Potential

antiSMASH 5.0: updates to the secondary metabolite genome mining pipeline

(2019) Kai Blin et al.   NUCLEIC ACIDS RESEARCH

RiPP antibiotics: biosynthesis and engineering potential

(2018) Graham A Hudson et al.   CURRENT OPINION IN MICROBIOLOGY

Recent advances in activating silent biosynthetic gene clusters in bacteria

(2018) Dainan Mao et al.   CURRENT OPINION IN MICROBIOLOGY

Streptomyces species: Ideal chassis for natural product discovery and overproduction

(2018) Ran Liu et al.   METABOLIC ENGINEERING

luxR Homolog-Linked Biosynthetic Gene Clusters in Proteobacteria

(2018) Carolyn A. Brotherton et al.   mSystems

Simulacricoccus ruber gen. nov., sp. nov., a microaerotolerant, non-fruiting, myxospore-forming soil myxobacterium and emended description of the family Myxococcaceae

(2018) Ronald Garcia et al.   INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY

Natural product drug discovery in the genomic era: realities, conjectures, misconceptions, and opportunities

(2018) Richard H. Baltz   JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY

Genome properties in 2019: a new companion database to InterPro for the inference of complete functional attributes

(2018) Lorna J Richardson et al.   NUCLEIC ACIDS RESEARCH

The antiSMASH database version 2: a comprehensive resource on secondary metabolite biosynthetic gene clusters

(2018) Kai Blin et al.   NUCLEIC ACIDS RESEARCH

Analysis of the Genome and Metabolome of Marine Myxobacteria Reveals High Potential for Biosynthesis of Novel Specialized Metabolites

(2018) Jamshid Amiri Moghaddam et al.   Scientific Reports

Genome Sequencing and Pan-Genome Analysis of 23 Corallococcus spp. Strains Reveal Unexpected Diversity, With Particular Plasticity of Predatory Gene Sets

(2018) Paul G. Livingstone et al.   Frontiers in Microbiology

Natural products from myxobacteria: novel metabolites and bioactivities

(2017) J. Herrmann et al.   NATURAL PRODUCT REPORTS

antiSMASH 4.0—improvements in chemistry prediction and gene cluster boundary identification

(2017) Kai Blin et al.   NUCLEIC ACIDS RESEARCH

The Myxobacterium Myxococcus xanthus Can Sense and Respond to the Quorum Signals Secreted by Potential Prey Organisms

(2017) Daniel G. Lloyd et al.   Frontiers in Microbiology

Isolation and Biosynthetic Analysis of Haliamide, a New PKS-NRPS Hybrid Metabolite from the Marine Myxobacterium Haliangium ochraceum

(2016) Yuwei Sun et al.   MOLECULES

Quorum sensing signal–response systems in Gram-negative bacteria

(2016) Kai Papenfort et al.   NATURE REVIEWS MICROBIOLOGY

Quorum Sensing: An Under-Explored Phenomenon in the Phylum Actinobacteria

(2016) Ashish V. Polkade et al.   Frontiers in Microbiology

Myxobacteria: Moving, Killing, Feeding, and Surviving Together

(2016) José Muñoz-Dorado et al.   Frontiers in Microbiology

Aminoglycoside Antibiotics: New Insights into the Biosynthetic Machinery of Old Drugs

(2015) Fumitaka Kudo et al.   CHEMICAL RECORD

Butyrolactone signalling circuits for synthetic biology

(2015) Marc Biarnes-Carrera et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

How Myxobacteria Cooperate

(2015) Pengbo Cao et al.   JOURNAL OF MOLECULAR BIOLOGY

Minimum Information about a Biosynthetic Gene cluster

(2015) Marnix H Medema et al.   Nature Chemical Biology

antiSMASH 3.0—a comprehensive resource for the genome mining of biosynthetic gene clusters

(2015) Tilmann Weber et al.   NUCLEIC ACIDS RESEARCH

Cystobactamids: Myxobacterial Topoisomerase Inhibitors Exhibiting Potent Antibacterial Activity

(2014) Sascha Baumann et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Characterization of the Gene Cluster CYP264B1-geoA fromSorangium cellulosumSo ce56: Biosynthesis of (+)-Eremophilene and Its Hydroxylation

(2014) Alexander Schifrin et al.   CHEMBIOCHEM

Biosynthesis of Crocacin Involves an Unusual Hydrolytic Release Domain Showing Similarity to Condensation Domains

(2014) Stefan Müller et al.   CHEMISTRY & BIOLOGY

A highly unusual polyketide synthase directs dawenol polyene biosynthesis in Stigmatella aurantiaca

(2014) Corina Oßwald et al.   JOURNAL OF BIOTECHNOLOGY

A multifunctional enzyme is involved in bacterial ether lipid biosynthesis

(2014) Wolfram Lorenzen et al.   Nature Chemical Biology

Cystomanamides: Structure and Biosynthetic Pathway of a Family of Glycosylated Lipopeptides from Myxobacteria

(2014) Lena Etzbach et al.   ORGANIC LETTERS

Two Lipid Signals Guide Fruiting Body Development of Myxococcus xanthus

(2014) S. Bhat et al.   mBio

Characteristics and activity analysis of epothilone operon promoters from Sorangium cellulosum strains in Escherichia coli

(2013) Li-Ping Zhu et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Elucidation of Gephyronic Acid Biosynthetic Pathway Revealed Unexpected SAM-Dependent Methylations

(2013) Jeanette Young et al.   JOURNAL OF NATURAL PRODUCTS

Discovery of the Rhizopodin Biosynthetic Gene Cluster in Stigmatella aurantiaca Sg a15 by Genome Mining

(2012) Dominik Pistorius et al.   CHEMBIOCHEM

Myxoprincomide: A Natural Product from Myxococcus xanthus Discovered by Comprehensive Analysis of the Secondary Metabolome

(2011) Niña Socorro Cortina et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Biogeography and phylogenetic diversity of a cluster of exclusively marine myxobacteria

(2011) Thorsten Brinkhoff et al.   ISME Journal

An Unusual Thioesterase Promotes Isochromanone Ring Formation in Ajudazol Biosynthesis

(2010) Kathrin Buntin et al.   CHEMBIOCHEM

Analysis of the Sorangicin Gene Cluster Reinforces the Utility of a Combined Phylogenetic/Retrobiosynthetic Analysis for Deciphering Natural Product Assembly by trans-AT PKS

(2010) Herbert Irschik  et al.   CHEMBIOCHEM

Unusual Chemistry in the Biosynthesis of the Antibiotic Chondrochlorens

(2009) Shwan Rachid et al.   CHEMISTRY & BIOLOGY

DKxanthene Biosynthesis—Understanding the Basis for Diversity-Oriented Synthesis in Myxobacterial Secondary Metabolism

(2008) Peter Meiser et al.   CHEMISTRY & BIOLOGY

Stereochemical Determination and Complex Biosynthetic Assembly of Etnangien, a Highly Potent RNA Polymerase Inhibitor from the Myxobacterium Sorangium cellulosum

(2008) Dirk Menche et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Myxochelin Biosynthesis: Direct Evidence for Two- and Four-Electron Reduction of a Carrier Protein-Bound Thioester

(2008) Yanyan Li et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY