Genome-Based Studies of Marine Microorganisms to Maximize the Diversity of Natural Products Discovery for Medical Treatments

Secondary metabolites of fungi from marine habitats

(2011) Mostafa E. Rateb et al.   NATURAL PRODUCT REPORTS

Isolation and Characterization of the Gene Cluster for Biosynthesis of the Thiopeptide Antibiotic TP-1161

(2010) K. Engelhardt et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Genome-wide inference of regulatory networks in Streptomyces coelicolor

(2010) Marlene Castro-Melchor et al.   BMC GENOMICS

The Discovery of Salinosporamide K from the Marine Bacterium “Salinispora pacifica” by Genome Mining Gives Insight into Pathway Evolution

(2010) Alessandra S. Eustáquio et al.   CHEMBIOCHEM

Marine pharmacology in 2007–8: Marine compounds with antibacterial, anticoagulant, antifungal, anti-inflammatory, antimalarial, antiprotozoal, antituberculosis, and antiviral activities; affecting the immune and nervous system, and other miscellaneous mechanisms of action

(2010) Alejandro M.S. Mayer et al.   COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY

The expanding role of marine microbes in pharmaceutical development

(2010) Amanda L Waters et al.   CURRENT OPINION IN BIOTECHNOLOGY

Genome mining for ribosomally synthesized natural products

(2010) Juan E Velásquez et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Genome Sequence of Kitasatospora setae NBRC 14216T: An Evolutionary Snapshot of the Family Streptomycetaceae

(2010) N. Ichikawa et al.   DNA RESEARCH

Marine natural product drug discovery: Leads for treatment of inflammation, cancer, infections, and neurological disorders

(2010) Francisco A. Villa et al.   IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY

Single-cell genomics reveals the lifestyle of Poribacteria, a candidate phylum symbiotically associated with marine sponges

(2010) Alexander Siegl et al.   ISME Journal

Genome Sequence of the Milbemycin-Producing Bacterium Streptomyces bingchenggensis

(2010) X.-J. Wang et al.   JOURNAL OF BACTERIOLOGY

Draft Genome Sequence of Streptomyces clavuligerus NRRL 3585, a Producer of Diverse Secondary Metabolites

(2010) J. Y. Song et al.   JOURNAL OF BACTERIOLOGY

Genome-Based Characterization of Two Prenylation Steps in the Assembly of the Stephacidin and Notoamide Anticancer Agents in a Marine-DerivedAspergillussp.

(2010) Yousong Ding et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Deletion of a regulatory gene within the cpk gene cluster reveals novel antibacterial activity in Streptomyces coelicolor A3(2)

(2010) M. Gottelt et al.   MICROBIOLOGY-SGM

The unique mechanistic transformations involved in the biosynthesis of modular natural products from marine cyanobacteria

(2010) Adam C. Jones et al.   NATURAL PRODUCT REPORTS

A sea of biosynthesis: marine natural products meet the molecular age

(2010) Amy L. Lane et al.   NATURAL PRODUCT REPORTS

Methods and options for the heterologous production of complex natural products

(2010) Haoran Zhang et al.   NATURAL PRODUCT REPORTS

SBSPKS: structure based sequence analysis of polyketide synthases

(2010) Swadha Anand et al.   NUCLEIC ACIDS RESEARCH

Microbisporicin gene cluster reveals unusual features of lantibiotic biosynthesis in actinomycetes

(2010) L. C. Foulston et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The odyssey of marine pharmaceuticals: a current pipeline perspective

(2010) Alejandro M.S. Mayer et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Marine microbial genomics in Europe: current status and perspectives

(2010) Frank Oliver Glöckner et al.   Microbial Biotechnology

Automated genome mining for natural products

(2009) Michael HT Li et al.   BMC BIOINFORMATICS

New tricks from ancient algae: natural products biosynthesis in marine cyanobacteria

(2009) Adam C Jones et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Chasing the treasures of the sea—bacterial marine natural products

(2009) Tobias AM Gulder et al.   CURRENT OPINION IN MICROBIOLOGY

Advances in the Understanding and Use of the Genomic Base of Microbial Secondary Metabolite Biosynthesis for the Discovery of New Natural Products⊥

(2009) James B. McAlpine   JOURNAL OF NATURAL PRODUCTS

Biosynthetic Gene-Based Secondary Metabolite Screening: A New Diterpene, Methyl Phomopsenonate, from the FungusPhomopsis amygdali

(2009) Tomonobu Toyomasu et al.   JOURNAL OF ORGANIC CHEMISTRY

Discovery of 3-Formyl-Tyrosine Metabolites fromPseudoalteromonas tunicatathrough Heterologous Expression

(2009) Leah C. Blasiak et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Genomic basis for natural product biosynthetic diversity in the actinomycetes

(2009) Markus Nett et al.   NATURAL PRODUCT REPORTS

Metagenomic approaches to natural products from free-living and symbiotic organisms

(2009) Sean F. Brady et al.   NATURAL PRODUCT REPORTS

A proteomics approach to discovering natural products and their biosynthetic pathways

(2009) Stefanie B Bumpus et al.   NATURE BIOTECHNOLOGY

Polyketide assembly lines of uncultivated sponge symbionts from structure-based gene targeting

(2009) Katja M Fisch et al.   Nature Chemical Biology

The Genomes On Line Database (GOLD) in 2009: status of genomic and metagenomic projects and their associated metadata

(2009) Konstantinos Liolios et al.   NUCLEIC ACIDS RESEARCH

Cultivation-independent approaches to investigate the chemistry of marine symbiotic bacteria

(2009) Agustinus Uria et al.   PHYTOCHEMISTRY REVIEWS

Genome Sequence of the Streptomycin-Producing Microorganism Streptomyces griseus IFO 13350

(2008) Y. Ohnishi et al.   JOURNAL OF BACTERIOLOGY

Antibiotic Overproduction inStreptomyces coelicolorA3(2) Mediated by Phosphofructokinase Deletion

(2008) Irina Borodina et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Visualizing the spatial distribution of secondary metabolites produced by marine cyanobacteria and sponges via MALDI-TOF imaging

(2008) Eduardo Esquenazi et al.   Molecular BioSystems

ClustScan : an integrated program package for the semi-automatic annotation of modular biosynthetic gene clusters and in silico prediction of novel chemical structures

(2008) Antonio Starcevic et al.   NUCLEIC ACIDS RESEARCH

2-Alkyl-4-hydroxymethylfuran-3-carboxylic acids, antibiotic production inducers discovered by Streptomyces coelicolor genome mining

(2008) C. Corre et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Panning for chemical gold: marine bacteria as a source of new therapeutics

(2008) Philip G. Williams   TRENDS IN BIOTECHNOLOGY