Bacteriocins — a viable alternative to antibiotics?

ComparativeIn VitroActivities of LFF571 against Clostridium difficile and 630 Other Intestinal Strains of Aerobic and Anaerobic Bacteria

(2012) Diane M. Citron et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

The Natural Antimicrobial Peptide Subtilosin Acts Synergistically with Glycerol Monolaurate, Lauric Arginate, and ε-Poly-l-Lysine against Bacterial Vaginosis-Associated Pathogens but Not Human Lactobacilli

(2012) Katia Sutyak Noll et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Efficacy of LFF571 in a Hamster Model of Clostridium difficile Infection

(2012) Anna Trzasko et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Mechanism of Action of and Mechanism of Reduced Susceptibility to the Novel Anti-Clostridium difficile Compound LFF571

(2012) J. A. Leeds et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Influence of Adhesion and Bacteriocin Production by Lactobacillus salivarius on the Intestinal Epithelial Cell Transcriptional Response

(2012) John O'Callaghan et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Generation of an actagardine A variant library through saturation mutagenesis

(2012) Steven Boakes et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Synthetic peptides derived from the sequence of a lasso peptide microcin J25 show antibacterial activity

(2012) Rania Soudy et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Microcin C: biosynthesis and mechanisms of bacterial resistance

(2012) Konstantin Severinov et al.   Future Microbiology

Plant-derived antimicrobial compounds: alternatives to antibiotics

(2012) Dianella Savoia   Future Microbiology

Nisin F-loaded brushite bone cement prevented the growth of Staphylococcus aureus in vivo

(2012) A.D. van Staden et al.   JOURNAL OF APPLIED MICROBIOLOGY

Structural and Functional Characterization of Microcin C Resistance Peptidase MccF from Bacillus anthracis

(2012) Boguslaw Nocek et al.   JOURNAL OF MOLECULAR BIOLOGY

The Synthesis of Active and Stable Diaminopimelate Analogues of the Lantibiotic Peptide Lactocin S

(2012) Avena C. Ross et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Synthesis of the Bacteriocin Glycopeptide Sublancin 168 and S-Glycosylated Variants

(2012) Yves S. Y. Hsieh et al.   ORGANIC LETTERS

Structure and Biosynthesis of the Antibiotic Bottromycin D

(2012) Yanpeng Hou et al.   ORGANIC LETTERS

Overview on the recent study of antimicrobial peptides: Origins, functions, relative mechanisms and application

(2012) Yanmei Li et al.   PEPTIDES

Effect of Lactobacillus salivarius Bacteriocin Abp118 on the Mouse and Pig Intestinal Microbiota

(2012) Eliette Riboulet-Bisson et al.   PLoS One

Identification and Characterization of Microcin S, a New Antibacterial Peptide Produced by Probiotic Escherichia coli G3/10

(2012) Anke Zschüttig et al.   PLoS One

ThioFinder: A Web-Based Tool for the Identification of Thiopeptide Gene Clusters in DNA Sequences

(2012) Jing Li et al.   PLoS One

Lantibiotics from Geobacillus thermodenitrificans

(2012) N. Garg et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Metagenome Mining Reveals Polytheonamides as Posttranslationally Modified Ribosomal Peptides

(2012) M. F. Freeman et al.   SCIENCE

Identification, Characterization, and Recombinant Expression of Epidermicin NI01, a Novel Unmodified Bacteriocin Produced by Staphylococcus epidermidis That Displays Potent Activity against Staphylococci

(2011) Stephanie Sandiford et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Mechanisms of Resistance to Bacteriocins Targeting the Mannose Phosphotransferase System

(2011) Morten Kjos et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Bacteriocin Production: a Probiotic Trait?

(2011) Alleson Dobson et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

AS-48 bacteriocin: close to perfection

(2011) Marina Sánchez-Hidalgo et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Thiazole/oxazole-modified microcins: complex natural products from ribosomal templates

(2011) Joel O Melby et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Bacteriophage therapy: potential uses in the control of antibiotic-resistant pathogens

(2011) Ben Burrowes et al.   Expert Review of Anti-Infective Therapy

CysteineS-glycosylation, a new post-translational modification found in glycopeptide bacteriocins

(2011) Judith Stepper et al.   FEBS LETTERS

Enterocin CRL35 Inhibits Listeria monocytogenes in a Murine Model

(2011) Emiliano Salvucci et al.   Foodborne Pathogens and Disease

Production of bioactive substances by intestinal bacteria as a basis for explaining probiotic mechanisms: Bacteriocins and conjugated linoleic acid

(2011) Eileen F. O'Shea et al.   INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY

Effective antibacterials: at what cost? The economics of antibacterial resistance and its control

(2011) A. R. White et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Target recognition, resistance, immunity and genome mining of class II bacteriocins from Gram-positive bacteria

(2011) M. Kjos et al.   MICROBIOLOGY-SGM

Fix the antibiotics pipeline

(2011) Matthew A. Cooper et al.   NATURE

Stop the killing of beneficial bacteria

(2011) Martin Blaser   NATURE

Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease

(2011) Zeneng Wang et al.   NATURE

Sublancin is not a lantibiotic but an S-linked glycopeptide

(2011) Trent J Oman et al.   Nature Chemical Biology

Shifting the balance: antibiotic effects on host–microbiota mutualism

(2011) Benjamin P. Willing et al.   NATURE REVIEWS MICROBIOLOGY

Genome Mining for Radical SAM Protein Determinants Reveals Multiple Sactibiotic-Like Gene Clusters

(2011) Kiera Murphy et al.   PLoS One

Genome Mining Demonstrates the Widespread Occurrence of Gene Clusters Encoding Bacteriocins in Cyanobacteria

(2011) Hao Wang et al.   PLoS One

The ABC Transporter AnrAB Contributes to the Innate Resistance of Listeria monocytogenes to Nisin, Bacitracin, and Various  -Lactam Antibiotics

(2010) B. Collins et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Production of a Class II Two-Component Lantibiotic of Streptococcus pneumoniae Using the Class I Nisin Synthetic Machinery and Leader Sequence

(2010) J. A. Majchrzykiewicz et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Sensitization of Microcin J25-Resistant Strains by a Membrane-Permeabilizing Peptide

(2010) M. F. Pomares et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Synthesis of Trypsin-Resistant Variants of the Listeria-Active Bacteriocin Salivaricin P

(2010) E. F. O'Shea et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Sources of novel antibiotics—aside the common roads

(2010) Stefano Donadio et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Cyanobactins—ribosomal cyclic peptides produced by cyanobacteria

(2010) Kaarina Sivonen et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Bottromycin derivatives: Efficient chemical modifications of the ester moiety and evaluation of anti-MRSA and anti-VRE activities

(2010) Yutaka Kobayashi et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

In silico analysis highlights the frequency and diversity of type 1 lantibiotic gene clusters in genome sequenced bacteria

(2010) Alan J Marsh et al.   BMC GENOMICS

Identification of Lactobacillus plantarum genes modulating the cytokine response of human peripheral blood mononuclear cells

(2010) Saskia van Hemert et al.   BMC MICROBIOLOGY

Genome mining for ribosomally synthesized natural products

(2010) Juan E Velásquez et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Probiotics in Perspective

(2010) Fergus Shanahan   GASTROENTEROLOGY

Molecular Determinants of Microbial Resistance to Thiopeptide Antibiotics

(2010) Sascha Baumann et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The ability of nisin F to control Staphylococcus aureus infection in the peritoneal cavity, as studied in mice

(2010) A.M. Brand et al.   LETTERS IN APPLIED MICROBIOLOGY

Bacteriocin as Weapons in the Marine Animal-Associated Bacteria Warfare: Inventory and Potential Applications as an Aquaculture Probiotic

(2010) Florie Desriac et al.   Marine Drugs

The dawning of a ‘Golden era’ in lantibiotic bioengineering

(2010) Des Field et al.   MOLECULAR MICROBIOLOGY

Gut Microbiota in Health and Disease

(2010) Inna Sekirov et al.   PHYSIOLOGICAL REVIEWS

Identification of Genetic Loci in Lactobacillus plantarum That Modulate the Immune Response of Dendritic Cells Using Comparative Genome Hybridization

(2010) Marjolein Meijerink et al.   PLoS One

Bacteriocins to control Campylobacter spp. in poultry--A review

(2010) E. A. Svetoch et al.   POULTRY SCIENCE

Genome mining and genetic analysis of cypemycin biosynthesis reveal an unusual class of posttranslationally modified peptides

(2010) J. Claesen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Thuricin CD, a posttranslationally modified bacteriocin with a narrow spectrum of activity against Clostridium difficile

(2010) M. C. Rea et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Effect of broad- and narrow-spectrum antimicrobials on Clostridium difficile and microbial diversity in a model of the distal colon

(2010) M. C. Rea et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

To protect peptide pharmaceuticals against peptidases

(2010) R. Rink et al.   JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS

Elucidation of the Molecular Mechanisms of Action of the Natural Antimicrobial Peptide Subtilosin Against the Bacterial Vaginosis-associated Pathogen Gardnerella vaginalis

(2010) Katia Sutyak Noll et al.   Probiotics and Antimicrobial Proteins

In Vivo Activities of Recombinant Divercin V41 and Its Structural Variants against Listeria monocytogenes

(2009) J. Rihakova et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

The Large Mechanosensitive Channel MscL Determines Bacterial Susceptibility to the Bacteriocin Sublancin 168

(2009) T. R. H. M. Kouwen et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Isolation and Characterization of Two Members of the Siderophore-Microcin Family, Microcins M and H47

(2009) G. Vassiliadis et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Novel Mechanism for Nisin Resistance via Proteolytic Degradation of Nisin by the Nisin Resistance Protein NSR

(2009) Z. Sun et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Highly Diverse Cyanobactins in Strains of the Genus Anabaena

(2009) N. Leikoski et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Identification of a Novel Two-Peptide Lantibiotic, Lichenicidin, following Rational Genome Mining for LanM Proteins

(2009) M. Begley et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Nocathiacin analogs: Synthesis and antibacterial activity of novel water-soluble amides

(2009) Libo Xu et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

The Structure and Biological Aspects of Peptide Antibiotic Microcin J25

(2009) Paula Vincent et al.   CURRENT MEDICINAL CHEMISTRY

Antibacterial and Antitumorigenic Properties of Microcin E492, a Pore- Forming Bacteriocin

(2009) R. Lagos et al.   CURRENT PHARMACEUTICAL BIOTECHNOLOGY

Lantibiotics: Mode of Action, Biosynthesis and Bioengineering

(2009) G. Bierbaum et al.   CURRENT PHARMACEUTICAL BIOTECHNOLOGY

The glucagon receptor antagonist BI-32169 constitutes a new class of lasso peptides

(2009) Thomas A. Knappe et al.   FEBS LETTERS

Interactions between two carnobacteriocins Cbn BM1 and Cbn B2 from Carnobacterium maltaromaticum CP5 on target bacteria and Caco-2 cells

(2009) Jordane Jasniewski et al.   FOOD AND CHEMICAL TOXICOLOGY

Pediocin PA-1 and a pediocin producing Lactobacillus plantarum strain do not change the HMA rat microbiota

(2009) Nete Bernbom et al.   INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY

In vivo study on the effectiveness of pediocin PA-1 and Pediococcus acidilactici UL5 at inhibiting Listeria monocytogenes

(2009) Nassra Dabour et al.   INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY

A comparison of the activities of lacticin 3147 and nisin against drug-resistant Staphylococcus aureus and Enterococcus species

(2009) C. Piper et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Synthetic Microcin C Analogs Targeting Different Aminoacyl-tRNA Synthetases

(2009) P. Van de Vijver et al.   JOURNAL OF BACTERIOLOGY

Thiazomycins, Thiazolyl Peptide Antibiotics fromAmycolatopsis fastidiosa

(2009) Chaowei Zhang et al.   JOURNAL OF NATURAL PRODUCTS

In Vitro Mutasynthesis of Lantibiotic Analogues Containing Nonproteinogenic Amino Acids

(2009) Matthew R. Levengood et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Ribosomally Synthesized Thiopeptide Antibiotics Targeting Elongation Factor Tu

(2009) Rowan P. Morris et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Cross-immunity and immune mimicry as mechanisms of resistance to the lantibiotic lacticin 3147

(2009) Lorraine A. Draper et al.   MOLECULAR MICROBIOLOGY

Recent advances in thiopeptideantibiotic biosynthesis

(2009) Chaoxuan Li et al.   NATURAL PRODUCT REPORTS

Thirteen posttranslational modifications convert a 14-residue peptide into the antibiotic thiocillin

(2009) Laura C. Wieland Brown et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Capacity of Human Nisin- and Pediocin-Producing Lactic Acid Bacteria To Reduce Intestinal Colonization by Vancomycin-Resistant Enterococci

(2008) M. Millette et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

The Vancomycin−Nisin(1−12) Hybrid Restores Activity against Vancomycin Resistant Enterococci†

(2008) Christopher J. Arnusch et al.   BIOCHEMISTRY

Predominance of a bacteriocin-producing Lactobacillus salivarius component of a five-strain probiotic in the porcine ileum and effects on host immune phenotype

(2008) Maria C. Walsh et al.   FEMS MICROBIOLOGY ECOLOGY

Escherichia coli Peptidase A, B, or N Can Process Translation Inhibitor Microcin C

(2008) T. Kazakov et al.   JOURNAL OF BACTERIOLOGY

Inactivating Methicillin-Resistant Staphylococcus aureus and Other Pathogens by Use of Bacteriocins OR-7 and E 50-52

(2008) E. A. Svetoch et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Isolation, Structure, and Antibacterial Activity of Philipimycin, A Thiazolyl Peptide Discovered fromActinoplanes philippinensisMA7347

(2008) Chaowei Zhang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Nisin F in the treatment of respiratory tract infections caused byStaphylococcus aureus

(2008) M. De Kwaadsteniet et al.   LETTERS IN APPLIED MICROBIOLOGY

Modulation of Helicobacter pylori colonization with cranberry juice and Lactobacillus johnsonii La1 in children

(2008) Martin Gotteland et al.   NUTRITION

Isolation of the Bacillus subtilis antimicrobial peptide subtilosin from the dairy product-derived Bacillus amyloliquefaciens

(2007) K.E. Sutyak et al.   JOURNAL OF APPLIED MICROBIOLOGY