The Extracellular Matrix-Derived Biomarkers for Diagnosis, Prognosis, and Personalized Therapy of Malignant Tumors
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Title
The Extracellular Matrix-Derived Biomarkers for Diagnosis, Prognosis, and Personalized Therapy of Malignant Tumors
Authors
Keywords
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Journal
Frontiers in Oncology
Volume 10, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2020-12-18
DOI
10.3389/fonc.2020.575569
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Note: Only part of the references are listed.- Anisotropic stiffness gradient-regulated mechanical guidance drives directional migration of cancer cells
- (2020) Haihui Zhang et al. Acta Biomaterialia
- Hyaluronan‐based hydrogels as versatile tumor‐like models: Tunable ECM and stiffness with genipin‐crosslinking
- (2020) Sarah Bonnesœur et al. JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A
- YAP1 is an independent prognostic marker in pancreatic cancer and associated with extracellular matrix remodeling
- (2020) Qimin Zhou et al. Journal of Translational Medicine
- Circular RNAs in the tumour microenvironment
- (2020) Zhonghua Ma et al. Molecular Cancer
- Sensitizing the Tumor Microenvironment to Immune Checkpoint Therapy
- (2020) Rachael M. Zemek et al. Frontiers in Immunology
- Esophageal Cancer Development: Crucial Clues Arising from the Extracellular Matrix
- (2020) Antonio Palumbo et al. Cells
- Fibronectin and Periostin as Prognostic Markers in Ovarian Cancer
- (2020) Katarzyna Aleksandra Kujawa et al. Cells
- Editorial: Heparan Sulfate Proteoglycans and Their Endogenous Modifying Enzymes: Cancer Players, Biomarkers and Therapeutic Targets
- (2020) Cinzia Lanzi et al. Frontiers in Oncology
- Biomarkers of tumor invasiveness in proteomics (Review)
- (2020) Daniel Pouliquen et al. INTERNATIONAL JOURNAL OF ONCOLOGY
- 3D Printing of Extracellular Matrix ( ECM )‐Mimicking Scaffolds: A Critical Review of the Current ECM Materials
- (2020) Kate Da Silva et al. JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A
- Cryptic collagen elements as signaling hubs in the regulation of tumor growth and metastasis
- (2020) XiangHua Han et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Matrix Stiffness and Colorectal Cancer
- (2020) Chongshun Liu et al. OncoTargets and Therapy
- A three-dimensional bioprinted model to evaluate the effect of stiffness on neuroblastoma cell cluster dynamics and behavior
- (2020) Ezequiel Monferrer et al. Scientific Reports
- Recent advances in mass spectrometry based clinical proteomics: applications to cancer research
- (2020) Andrew Macklin et al. Clinical Proteomics
- Automated Real-Time Tumor Pharmacokinetic Profiling in 3D Models: A Novel Approach for Personalized Medicine
- (2020) Jan F. Joseph et al. Pharmaceutics
- 3D Cell Culture-Based Global miRNA Expression Analysis Reveals miR-142-5p as a Theranostic Biomarker of Rectal Cancer Following Neoadjuvant Long-Course Treatment
- (2020) Linas Kunigenas et al. Biomolecules
- Matrix stiffness modulates patient-derived glioblastoma cell fates in 3D hydrogels
- (2020) Christine Wang et al. TISSUE ENGINEERING PART A
- Atomic force microscopy for revealing micro/nanoscale mechanics in tumor metastasis: from single cells to microenvironmental cues
- (2020) Mi Li et al. ACTA PHARMACOLOGICA SINICA
- The crosstalk between circular RNAs and the tumor microenvironment in cancer metastasis
- (2020) Ying Shao et al. Cancer Cell International
- Decellularized extracellular matrix scaffolds identify full-length collagen VI as a driver of breast cancer cell invasion in obesity and metastasis
- (2020) Andrew L. Wishart et al. Science Advances
- Blood-based extracellular matrix biomarkers are correlated with clinical outcome after PD-1 inhibition in patients with metastatic melanoma
- (2020) Daan P Hurkmans et al. Journal for ImmunoTherapy of Cancer
- Durotaxis by Human Cancer Cells
- (2019) Brian J. DuChez et al. BIOPHYSICAL JOURNAL
- ADAM8 in invasive cancers: links to tumor progression, metastasis, and chemoresistance
- (2019) Catharina Conrad et al. CLINICAL SCIENCE
- Quantitative phase imaging reveals matrix stiffness-dependent growth and migration of cancer cells
- (2019) Yanfen Li et al. Scientific Reports
- Tumor Extracellular Matrix Remodeling: New Perspectives as a Circulating Tool in the Diagnosis and Prognosis of Solid Tumors
- (2019) Marta Giussani et al. Cells
- 3D Mammary Epithelial Cell Models: A Goldmine of DCIS Biomarkers and Morphogenetic Mechanisms
- (2019) Stefano Rossetti et al. Cancers
- Collagen density regulates the activity of tumor-infiltrating T cells
- (2019) Dorota E. Kuczek et al. Journal for ImmunoTherapy of Cancer
- Extracellular matrix protein 1 (ECM1) is associated with carcinogenesis potential of human bladder cancer
- (2019) Zhicai Wang et al. OncoTargets and Therapy
- Dynamically stiffened matrix promotes malignant transformation of mammary epithelial cells via collective mechanical signaling
- (2019) Matthew G. Ondeck et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Tenascin XB Is a Novel Diagnostic Marker for Malignant Mesothelioma
- (2019) KOJI NAKAYAMA et al. ANTICANCER RESEARCH
- Development of a Colorectal Cancer 3D Micro-tumor Construct Platform From Cell Lines and Patient Tumor Biospecimens for Standard-of-Care and Experimental Drug Screening
- (2019) Steven Forsythe et al. ANNALS OF BIOMEDICAL ENGINEERING
- ALDH1 – A new immunohistochemical diagnostic marker for Schwann cell-derived tumors
- (2019) Friederike Liesche et al. CLINICAL NEUROPATHOLOGY
- Extracellular matrix proteins as circulating biomarkers for the diagnosis of non-small cell lung cancer patients
- (2019) Daniela Frezzetti et al. Journal of Thoracic Disease
- Tenascin-C expression contributes to pediatric brainstem glioma tumor phenotype and represents a novel biomarker of disease
- (2019) J. Qi et al. Acta Neuropathologica Communications
- Overexpression of BMP1 reflects poor prognosis in clear cell renal cell carcinoma
- (2019) Wen Xiao et al. CANCER GENE THERAPY
- The topology of vitronectin: A complementary feature for neuroblastoma risk classification based on computer‐aided detection
- (2019) Pablo Vicente‐Munuera et al. INTERNATIONAL JOURNAL OF CANCER
- A Soft Matrix Enhances the Cancer Stem Cell Phenotype of HCC Cells
- (2019) Boren Tian et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Offsetting Expression Profiles of Prognostic Markers in Prostate Tumor vs. Its Microenvironment
- (2019) Zhenyu Jia et al. Frontiers in Oncology
- The Role of the Extracellular Matrix in Cancer Stemness
- (2019) Sameera Nallanthighal et al. Frontiers in Cell and Developmental Biology
- Tissue mimetic 3D scaffold for breast tumor-derived organoid culture toward personalized chemotherapy
- (2019) Biswadeep Nayak et al. COLLOIDS AND SURFACES B-BIOINTERFACES
- Clinical Relevance of Collagen Protein Degradation Markers C3M and C4M in the Serum of Breast Cancer Patients Treated with Neoadjuvant Therapy in the GeparQuinto Trial
- (2019) Malgorzata Banys-Paluchowski et al. Cancers
- Identification of SPP1 as an Extracellular Matrix Signature for Metastatic Castration-Resistant Prostate Cancer
- (2019) Xiaocong Pang et al. Frontiers in Oncology
- 1250PExtracellular matrix and tissue derived metabolites in a liquid biopsy identifies endotypes of metastatic melanoma patients with differential response to immune checkpoint inhibitor treatment
- (2019) N Willumsen et al. ANNALS OF ONCOLOGY
- Extracellular Matrix Alterations in Metastatic Processes
- (2019) Paolillo et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Higher matrix stiffness as an independent initiator triggers epithelial-mesenchymal transition and facilitates HCC metastasis
- (2019) Yinying Dong et al. Journal of Hematology & Oncology
- 3D cell culture stimulates the secretion of in vivo like extracellular vesicles
- (2019) Sirisha Thippabhotla et al. Scientific Reports
- Upregulation of PD-L1 expression in breast cancer cells through the formation of 3D multicellular cancer aggregates under different chemical and mechanical conditions
- (2019) Shohreh Azadi et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- The role of extracellular matrix in biomechanics and its impact on bioengineering of cells and 3D tissues
- (2019) Max Urbanczyk et al. MATRIX BIOLOGY
- The Extracellular, Cellular, and Nuclear Stiffness, a Trinity in the Cancer Resistome—A Review
- (2019) Sara Sofia Deville et al. Frontiers in Oncology
- Viscoelastic properties of human pancreatic tumors and in vitro constructs to mimic mechanical properties
- (2018) Andres Rubiano et al. Acta Biomaterialia
- P16 is a useful supplemental diagnostic marker of pulmonary small cell carcinoma in small biopsies and cytology specimens
- (2018) Marián Švajdler et al. Annals of Diagnostic Pathology
- Regulation of PD-L1 expression by matrix stiffness in lung cancer cells
- (2018) Ayako Miyazawa et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- An elevated expression of serum exosomal microRNA-191, − 21, −451a of pancreatic neoplasm is considered to be efficient diagnostic marker
- (2018) Takuma Goto et al. BMC CANCER
- The extracellular matrix as a key regulator of intracellular signalling networks
- (2018) Jordan F Hastings et al. BRITISH JOURNAL OF PHARMACOLOGY
- Heightened CXCR4 and CXCL12 expression in NF1-associated neurofibromas
- (2018) Beren Karaosmanoglu et al. CHILDS NERVOUS SYSTEM
- Tumor elastography and its association with collagen and the tumor microenvironment.
- (2018) Johannes Riegler et al. CLINICAL CANCER RESEARCH
- Reshaping the Tumor Stroma for Treatment of Pancreatic Cancer
- (2018) Claire Vennin et al. GASTROENTEROLOGY
- Fibroblasts in the Tumor Microenvironment: Shield or Spear?
- (2018) Twana Alkasalias et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Extracellular matrix proteins as diagnostic markers of breast carcinoma
- (2018) Marta Giussani et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Highly Accurate Identification of Cystic Precursor Lesions of Pancreatic Cancer Through Targeted Mass Spectrometry: A Phase IIc Diagnostic Study
- (2018) Karolina S. Jabbar et al. JOURNAL OF CLINICAL ONCOLOGY
- Targeting extracellular matrix stiffness to attenuate disease: From molecular mechanisms to clinical trials
- (2018) Marsha C. Lampi et al. Science Translational Medicine
- Tumstatin, a Matrikine Derived from Collagen Type IVα3, is Elevated in Serum from Patients with Non–Small Cell Lung Cancer
- (2018) Signe Holm Nielsen et al. Translational Oncology
- Alpha-Fetoprotein and Hepatocellular Carcinoma Immunity
- (2018) Xiaoping Wang et al. Canadian Journal of Gastroenterology and Hepatology
- Tumor matrix remodeling and novel immunotherapies: the promise of matrix-derived immune biomarkers
- (2018) Muhammad Umair Mushtaq et al. Journal for ImmunoTherapy of Cancer
- Cell Adhesion and Matrix Stiffness: Coordinating Cancer Cell Invasion and Metastasis
- (2018) Vasiliki Gkretsi et al. Frontiers in Oncology
- Defining the Role of Solid Stress and Matrix Stiffness in Cancer Cell Proliferation and Metastasis
- (2018) Maria Kalli et al. Frontiers in Oncology
- Diagnostic role of circulating extracellular matrix-related proteins in non-small cell lung cancer
- (2018) Francesca Andriani et al. BMC CANCER
- Identification of beta-arrestin-1 as a diagnostic biomarker in lung cancer
- (2018) Victoria El-Khoury et al. BRITISH JOURNAL OF CANCER
- Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries
- (2018) Freddie Bray et al. CA-A CANCER JOURNAL FOR CLINICIANS
- Tenascin-C as a prognostic determinant of colorectal cancer through induction of epithelial-to-mesenchymal transition and proliferation
- (2018) Zhaoting Yang et al. EXPERIMENTAL AND MOLECULAR PATHOLOGY
- Matrix metalloproteinase Mmp-1a is dispensable for normal growth and fertility in mice and promotes lung cancer progression by modulating inflammatory responses.
- (2018) Miriam Fanjul-Fernández et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Extracellular vesicle-associated miRNAs in ovarian cancer – design of an integrated NGS-based workflow for the identification of blood-based biomarkers for platinum-resistance
- (2018) Jan Dominik Kuhlmann et al. CLINICAL CHEMISTRY AND LABORATORY MEDICINE
- Non-invasive profiling of protease-specific elastin turnover in lung cancer: biomarker potential
- (2018) Jeppe Thorlacius-Ussing et al. JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY
- Non-invasive biomarkers derived from the extracellular matrix associate with response to immune checkpoint blockade (anti-CTLA-4) in metastatic melanoma patients
- (2018) Christina Jensen et al. Journal for ImmunoTherapy of Cancer
- ADAM8 expression in breast cancer derived brain metastases: Functional implications on MMP-9 expression and transendothelial migration in breast cancer cells
- (2017) Catharina Conrad et al. INTERNATIONAL JOURNAL OF CANCER
- Galectin-3 as a novel biomarker for disease diagnosis and a target for therapy (Review)
- (2017) Rui Dong et al. INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE
- Galectin-1 is a diagnostic marker involved in thyroid cancer progression
- (2017) Vanessa Arcolia et al. INTERNATIONAL JOURNAL OF ONCOLOGY
- Versican-Derived Matrikines Regulate Batf3–Dendritic Cell Differentiation and Promote T Cell Infiltration in Colorectal Cancer
- (2017) Chelsea Hope et al. JOURNAL OF IMMUNOLOGY
- Mapping Extracellular Matrix Proteins in Formalin-Fixed, Paraffin-Embedded Tissues by MALDI Imaging Mass Spectrometry
- (2017) Peggi M. Angel et al. JOURNAL OF PROTEOME RESEARCH
- Functional precision cancer medicine—moving beyond pure genomics
- (2017) Anthony Letai NATURE MEDICINE
- Quantitative proteomics identify Tenascin-C as a promoter of lung cancer progression and contributor to a signature prognostic of patient survival
- (2017) Vasilena Gocheva et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Matrix-Bound Nanovesicles Recapitulate Extracellular Matrix Effects on Macrophage Phenotype
- (2017) Luai Huleihel et al. TISSUE ENGINEERING PART A
- Deconstruction of a Metastatic Tumor Microenvironment Reveals a Common Matrix Response in Human Cancers
- (2017) Oliver M.T. Pearce et al. Cancer Discovery
- Spondin2 is a new prognostic biomarker for lung adenocarcinoma
- (2017) Xiaopeng Yuan et al. Oncotarget
- Diagnostic, Predictive, Prognostic, and Therapeutic Molecular Biomarkers in Third Millennium: A Breakthrough in Gastric Cancer
- (2017) Nicola Carlomagno et al. Biomed Research International
- Bringing 3D tumor models to the clinic - predictive value for personalized medicine
- (2017) Kathrin Halfter et al. Biotechnology Journal
- Matrix stiffness induces epithelial–mesenchymal transition and promotes chemoresistance in pancreatic cancer cells
- (2017) A J Rice et al. Oncogenesis
- 3D Culture as a Clinically Relevant Model for Personalized Medicine
- (2017) Eliza Li Shan Fong et al. SLAS Technology
- Extracellular matrix structure
- (2016) Achilleas D. Theocharis et al. ADVANCED DRUG DELIVERY REVIEWS
- Immunoregulatory roles of versican proteolysis in the myeloma microenvironment
- (2016) C. Hope et al. BLOOD
- Matrix-bound nanovesicles within ECM bioscaffolds
- (2016) L. Huleihel et al. Science Advances
- High-Throughput Assessment of Cellular Mechanical Properties
- (2015) Eric M. Darling et al. Annual Review of Biomedical Engineering
- Human breast cancer invasion and aggression correlates with ECM stiffening and immune cell infiltration
- (2015) I. Acerbi et al. Integrative Biology
- Biomarker: Predictive or Prognostic?
- (2015) Karla V. Ballman JOURNAL OF CLINICAL ONCOLOGY
- Hepatic metastatic niche: from normal to pre-metastatic and metastatic niche
- (2015) Shirin Azizidoost et al. TUMOR BIOLOGY
- Targeting ECM Disrupts Cancer Progression
- (2015) Freja A. Venning et al. Frontiers in Oncology
- The extracellular matrix modulates the hallmarks of cancer
- (2014) M. W. Pickup et al. EMBO REPORTS
- Matricryptins and matrikines: biologically active fragments of the extracellular matrix
- (2014) Sylvie Ricard-Blum et al. EXPERIMENTAL DERMATOLOGY
- The malignancy of metastatic ovarian cancer cells is increased on soft matrices through a mechanosensitive Rho-ROCK pathway
- (2014) D. J. McGrail et al. JOURNAL OF CELL SCIENCE
- Remodelling the extracellular matrix in development and disease
- (2014) Caroline Bonnans et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Decreased decorin expression in the tumor microenvironment
- (2014) Benedek Bozoky et al. Cancer Medicine
- ADAM8 expression in invasive breast cancer promotes tumor dissemination and metastasis
- (2013) Mathilde Romagnoli et al. EMBO Molecular Medicine
- Recurrent somatic mutation of FAT1 in multiple human cancers leads to aberrant Wnt activation
- (2013) Luc G T Morris et al. NATURE GENETICS
- Imaging aspects of the tumor stroma with therapeutic implications
- (2013) Lian Narunsky et al. PHARMACOLOGY & THERAPEUTICS
- Myeloid Progenitor Cells in the Premetastatic Lung Promote Metastases by Inducing Mesenchymal to Epithelial Transition
- (2012) D. Gao et al. CANCER RESEARCH
- The extracellular matrix: A dynamic niche in cancer progression
- (2012) Pengfei Lu et al. JOURNAL OF CELL BIOLOGY
- The nanomechanical signature of breast cancer
- (2012) Marija Plodinec et al. Nature Nanotechnology
- Breast cancer cells produce tenascin C as a metastatic niche component to colonize the lungs
- (2011) Thordur Oskarsson et al. NATURE MEDICINE
- VEGF-A and Tenascin-C produced by S100A4+ stromal cells are important for metastatic colonization
- (2011) J. T. O'Connell et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Overview of the Matrisome--An Inventory of Extracellular Matrix Constituents and Functions
- (2011) R. O. Hynes et al. Cold Spring Harbor Perspectives in Biology
- Proteoglycans: from structural compounds to signaling molecules
- (2009) Liliana Schaefer et al. CELL AND TISSUE RESEARCH
- Extracellular Matrix Molecules: Potential Targets in Pharmacotherapy
- (2009) H. Jarvelainen et al. PHARMACOLOGICAL REVIEWS
- The Extracellular Matrix: Not Just Pretty Fibrils
- (2009) R. O. Hynes SCIENCE
- SPARC: a matricellular regulator of tumorigenesis
- (2009) Shanna A. Arnold et al. Journal of Cell Communication and Signaling
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