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Title
Fibroblasts in the Tumor Microenvironment: Shield or Spear?
Authors
Keywords
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Journal
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Volume 19, Issue 5, Pages 1532
Publisher
MDPI AG
Online
2018-05-22
DOI
10.3390/ijms19051532
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- (2017) Begum Erdogan et al. JOURNAL OF CELL BIOLOGY
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- (2017) Youmna Attieh et al. JOURNAL OF CELL BIOLOGY
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- (2017) Twana Alkasalias et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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- (2017) Jia-Chi Ma et al. WORLD JOURNAL OF GASTROENTEROLOGY
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- (2017) Alexandros Glentis et al. Nature Communications
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- (2017) Xiongyan Wu et al. Oncotarget
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- (2016) Kazuyoshi Kise et al. ADVANCED DRUG DELIVERY REVIEWS
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- (2016) Antonio Castro-Castro et al. Annual Review of Cell and Developmental Biology
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- (2016) Nkechiyere G. Nwani et al. CANCER RESEARCH
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- (2016) Norihiro Sato et al. CANCER SCIENCE
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- (2016) S. Khazaei et al. Clinical & Translational Oncology
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- (2016) Fei Teng et al. Journal of Hematology & Oncology
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- (2016) Sebastian R. Nielsen et al. NATURE CELL BIOLOGY
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- (2016) Roberto Mayor et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Collagen-rich stroma in aggressive colon tumors induces mesenchymal gene expression and tumor cell invasion
- (2016) T T Vellinga et al. ONCOGENE
- SFRP2 augments WNT16B signaling to promote therapeutic resistance in the damaged tumor microenvironment
- (2016) Y Sun et al. ONCOGENE
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- (2016) Megan K. Ruhland et al. Nature Communications
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- (2016) Juanli Qiao et al. Oncotarget
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- (2016) Lauren E. Tracy et al. Advances in Wound Care
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- (2015) Eishu Hirata et al. CANCER CELL
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- (2015) Wenjing Pang et al. CANCER SCIENCE
- Confrontation of fibroblasts with cancer cells in vitro: gene network analysis of transcriptome changes and differential capacity to inhibit tumor growth
- (2015) Andrey Alexeyenko et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
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- (2015) Andreia L Bates et al. JOURNAL OF PATHOLOGY
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- (2014) S. S. Donatelli et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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- (2013) Kim H.T. Paraiso et al. BIOCHEMICAL PHARMACOLOGY
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- (2013) Thordur Oskarsson BREAST
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- (2013) G S Wong et al. BRITISH JOURNAL OF CANCER
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- (2013) M. Herrera et al. CLINICAL CANCER RESEARCH
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- (2013) A.L. WILLIS et al. JOURNAL OF MICROSCOPY
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- (2013) Fernando Calvo et al. NATURE CELL BIOLOGY
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- (2013) C J Foley et al. ONCOGENE
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- (2013) G Comito et al. ONCOGENE
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- (2013) Kavita S. Subramaniam et al. PLoS One
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- (2013) C. Feig et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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- (2013) Neil A. Turner VASCULAR PHARMACOLOGY
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- (2012) Elizabeth C. Lessey et al. BIOCHEMISTRY
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- (2012) A. Akhavan et al. CANCER RESEARCH
- Exosomes Mediate Stromal Mobilization of Autocrine Wnt-PCP Signaling in Breast Cancer Cell Migration
- (2012) Valbona Luga et al. CELL
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- (2012) Patsy S H Soon et al. ENDOCRINE-RELATED CANCER
- The extracellular matrix: A dynamic niche in cancer progression
- (2012) Pengfei Lu et al. JOURNAL OF CELL BIOLOGY
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- (2012) A.-C. Johansson et al. MOLECULAR CANCER RESEARCH
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- (2012) Peter Friedl et al. NATURE CELL BIOLOGY
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- (2012) Yu Sun et al. NATURE MEDICINE
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- (2012) Shannon Kidd et al. PLoS One
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- (2012) A. K. Mitra et al. Cancer Discovery
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- (2012) Yves A. DeClerck Cancer Discovery
- Bone Marrow-Derived Myofibroblasts Contribute to the Mesenchymal Stem Cell Niche and Promote Tumor Growth
- (2011) Michael Quante et al. CANCER CELL
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- (2011) Douglas Hanahan et al. CELL
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- (2011) T. R. Cox et al. Disease Models & Mechanisms
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- (2011) X. Luo et al. MOLECULAR CANCER RESEARCH
- Interactions between cancer stem cells and their niche govern metastatic colonization
- (2011) Ilaria Malanchi et al. NATURE
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- (2011) J. T. O'Connell et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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- (2010) A. Beliveau et al. GENES & DEVELOPMENT
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- (2009) N. Paland et al. MOLECULAR CANCER RESEARCH
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- (2009) Anthony J. Trimboli et al. NATURE
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- (2009) Pierre Farmer et al. NATURE MEDICINE
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- (2009) Debbie Liao et al. PLoS One
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- (2009) George Klein PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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