Hyaluronan‐based hydrogels as versatile tumor‐like models: Tunable ECM and stiffness with genipin‐crosslinking

Incorporation of types I and III collagen in tunable hyaluronan hydrogels for vocal fold tissue engineering

(2019) Tanaya Walimbe et al.   Acta Biomaterialia

Benchmarking to the Gold Standard: Hyaluronan‐Oxime Hydrogels Recapitulate Xenograft Models with In Vitro Breast Cancer Spheroid Culture

(2019) Alexander E. G. Baker et al.   ADVANCED MATERIALS

Targeting Hyaluronan Interactions for Glioblastoma Stem Cell Therapy

(2019) Joline S. Hartheimer et al.   Cancer Microenvironment

How tissue fluidity influences brain tumor progression

(2019) Kaspar-Josche Streitberger et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The influence of matrix stiffness on the behavior of brain metastatic breast cancer cells in a biomimetic hyaluronic acid hydrogel platform

(2018) Akshay A. Narkhede et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

Genipin induces cell death via intrinsic apoptosis pathways in human glioblastoma cells

(2018) Narges Ahani et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

The mechanical and pharmacological regulation of glioblastoma cell migration in 3D matrices

(2018) Pranita Kaphle et al.   JOURNAL OF CELLULAR PHYSIOLOGY

A hybrid genipin-crosslinked dual-sensitive hydrogel /nanostructured lipid carrier ocular drug delivery platform

(2018) Yibin Yu et al.   Asian Journal of Pharmaceutical Sciences

A “Cell-Friendly” Window for the Interaction of Cells with Hyaluronic Acid/Poly-l -Lysine Multilayers

(2017) Narayanan Madaboosi et al.   MACROMOLECULAR BIOSCIENCE

Genipin suppresses colorectal cancer cells by inhibiting the Sonic Hedgehog pathway

(2017) Bo Ram Kim et al.   Oncotarget

Quantification of effects of cancer on elastic properties of breast tissue by Atomic Force Microscopy

(2016) Arian Ansardamavandi et al.   Journal of the Mechanical Behavior of Biomedical Materials

Nano-mechanical signature of brain tumours

(2016) Gabriele Ciasca et al.   Nanoscale

Human breast cancer invasion and aggression correlates with ECM stiffening and immune cell infiltration

(2015) I. Acerbi et al.   Integrative Biology

Flow-perfusion bioreactor system for engineered breast cancer surrogates to be used in preclinical testing

(2015) Lauren E. Marshall et al.   Journal of Tissue Engineering and Regenerative Medicine

In vitro microenvironments to study breast cancer bone colonisation

(2014) Anna V. Taubenberger   ADVANCED DRUG DELIVERY REVIEWS

Genipin-Cross-Linked Layer-by-Layer Assemblies: Biocompatible Microenvironments To Direct Bone Cell Fate

(2014) Fabien Gaudière et al.   BIOMACROMOLECULES

CD44-Mediated Adhesion to Hyaluronic Acid Contributes to Mechanosensing and Invasive Motility

(2014) Yushan Kim et al.   MOLECULAR CANCER RESEARCH

Bioengineered 3D Brain Tumor Model To Elucidate the Effects of Matrix Stiffness on Glioblastoma Cell Behavior Using PEG-Based Hydrogels

(2014) Christine Wang et al.   MOLECULAR PHARMACEUTICS

Analysis of glycosaminoglycan-derived, precolumn, 2-aminoacridone–labeled disaccharides with LC-fluorescence and LC-MS detection

(2014) Nicola Volpi et al.   Nature Protocols

Direct Effect of Bevacizumab on Glioblastoma Cell Lines In Vitro

(2014) Thomas Simon et al.   NEUROMOLECULAR MEDICINE

Glioblastoma Behaviors in Three-Dimensional Collagen-Hyaluronan Composite Hydrogels

(2013) Shreyas S. Rao et al.   ACS Applied Materials & Interfaces

Regulation of glioma cell phenotype in 3D matrices by hyaluronic acid

(2013) Sara Pedron et al.   BIOMATERIALS

The mechanical control of nervous system development

(2013) K. Franze   DEVELOPMENT

Tumor cell migration in complex microenvironments

(2012) William J. Polacheck et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

The extracellular matrix: A dynamic niche in cancer progression

(2012) Pengfei Lu et al.   JOURNAL OF CELL BIOLOGY

Elucidating the mechanobiology of malignant brain tumors using a brain matrix-mimetic hyaluronic acid hydrogel platform

(2011) Badriprasad Ananthanarayanan et al.   BIOMATERIALS

Mitochondrial recoupling: a novel therapeutic strategy for cancer?

(2011) G Baffy et al.   BRITISH JOURNAL OF CANCER

Cellular Model of Warburg Effect Identifies Tumor Promoting Function of UCP2 in Breast Cancer and Its Suppression by Genipin

(2011) Vanniarajan Ayyasamy et al.   PLoS One

Evidence of different growth regimes coexisting within biomimetic Layer-by-Layer films

(2011) Khalil Abdelkebir et al.   Soft Matter

Preparation of collagen–chondroitin sulfate–hyaluronic acid hybrid hydrogel scaffolds and cell compatibility in vitro

(2010) Ling Zhang et al.   CARBOHYDRATE POLYMERS

Long-acting genipin derivative protects retinal ganglion cells from oxidative stress models in vitro and in vivo through the Nrf2/antioxidant response element signaling pathway

(2010) Yoshiki Koriyama et al.   JOURNAL OF NEUROCHEMISTRY

How deeply cells feel: methods for thin gels

(2010) Amnon Buxboim et al.   JOURNAL OF PHYSICS-CONDENSED MATTER

Elastin-derived peptides: Matrikines critical for glioblastoma cell aggressiveness in a 3-D system

(2009) Bérénice Coquerel et al.   GLIA

Collagens, stromal cell-derived factor-1α and basic fibroblast growth factor increase cancer cell invasiveness in a hyaluronan hydrogel

(2008) L. David et al.   CELL PROLIFERATION

Hyaluronan hydrogel: An appropriate three-dimensional model for evaluation of anticancer drug sensitivity

(2007) Laurent David et al.   Acta Biomaterialia