The Evolving Landscape of Exosomes in Neurodegenerative Diseases: Exosomes Characteristics and a Promising Role in Early Diagnosis

Salivary biomarkers in Alzheimer’s disease

(2020) Asta Tvarijonaviciute et al.   Clinical Oral Investigations

Perspectives in fluid biomarkers in neurodegeneration from the 2019 biomarkers in neurodegenerative diseases course—a joint PhD student course at University College London and University of Gothenburg

(2020) Pawel Obrocki et al.   Alzheimers Research & Therapy

Plasma and Serum Alpha-Synuclein as a Biomarker of Diagnosis in Patients With Parkinson's Disease

(2020) Chun-Wei Chang et al.   Frontiers in Neurology

Potential Roles of Exosomes in Parkinson’s Disease: From Pathogenesis, Diagnosis, and Treatment to Prognosis

(2020) Haiyang Yu et al.   Frontiers in Cell and Developmental Biology

Microglial exosomes facilitate α-synuclein transmission in Parkinson’s disease

(2020) Min Guo et al.   BRAIN

Biofluid Biomarkers in Parkinson's Disease: Clarity Amid Controversy

(2020) Sophia R.L. Vieira et al.   MOVEMENT DISORDERS

A Pilot Study of Urinary Exosomes in Alzheimer’s Disease

(2020) Ruihua Sun et al.   Neurodegenerative Diseases

Long Noncoding RNA POU3F3 and α-Synuclein in Plasma L1CAM Exosomes Combined with β-Glucocerebrosidase Activity: Potential Predictors of Parkinson’s Disease

(2020) Jing Zou et al.   Neurotherapeutics

CNS-Derived Blood Exosomes as a Promising Source of Biomarkers: Opportunities and Challenges

(2020) Simon Hornung et al.   Frontiers in Molecular Neuroscience

Extracellular Vesicles: Current Analytical Techniques for Detection and Quantification

(2020) Esther Serrano-Pertierra et al.   Biomolecules

Salivary lactoferrin as biomarker for Alzheimer's disease: Brain‐immunity interactions

(2020) Félix Bermejo‐Pareja et al.   Alzheimers & Dementia

Salivary exosomes: properties, medical applications, and isolation methods

(2020) Behzad Cheshmi et al.   MOLECULAR BIOLOGY REPORTS

Technologies and Standardization in Research on Extracellular Vesicles

(2020) Srujan Gandham et al.   TRENDS IN BIOTECHNOLOGY

Human salivary Raman fingerprint as biomarker for the diagnosis of Amyotrophic Lateral Sclerosis

(2020) C. Carlomagno et al.   Scientific Reports

TDP-43 Is Elevated in Plasma Neuronal-Derived Exosomes of Patients With Alzheimer’s Disease

(2020) Nan Zhang et al.   Frontiers in Aging Neuroscience

Increased Salivary microRNAs That Regulate DJ-1 Gene Expression as Potential Markers for Parkinson’s Disease

(2020) Yanmei Chen et al.   Frontiers in Aging Neuroscience

An miRNA fingerprint using neural-enriched extracellular vesicles from blood plasma: towards a biomarker for amyotrophic lateral sclerosis/motor neuron disease

(2020) Sandra Anne Banack et al.   Open Biology

Decreased salivary lactoferrin levels are specific to Alzheimer's disease

(2020) Marta González-Sánchez et al.   EBioMedicine

Levels of Interleukin-6 in Saliva, but Not Plasma, Correlate with Clinical Metrics in Huntington’s Disease Patients and Healthy Control Subjects

(2020) Jody Corey-Bloom et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Extracellular microvesicles/exosomes: discovery, disbelief, acceptance, and the future?

(2020) Mariusz Z. Ratajczak et al.   LEUKEMIA

Association between plasma exosome neurogranin and brain structure in patients with Alzheimer’s disease: a protocol study

(2020) MengFei He et al.   BMJ Open

Proteomic Profiling of Extracellular Vesicles Derived from Cerebrospinal Fluid of Alzheimer’s Disease Patients: A Pilot Study

(2020) Satoshi Muraoka et al.   Cells

A novel approach to correlate the salivary exosomes and their protein cargo in the progression of cognitive impairment into Alzheimer’s disease

(2020) Komal Rani et al.   JOURNAL OF NEUROSCIENCE METHODS

Identification of biomarkers for amyotrophic lateral sclerosis by comprehensive analysis of exosomal mRNAs in human cerebrospinal fluid

(2019) Kentaro Otake et al.   BMC Medical Genomics

Increased DJ-1 and α-Synuclein in Plasma Neural-Derived Exosomes as Potential Markers for Parkinson’s Disease

(2019) Zhen-Hua Zhao et al.   Frontiers in Aging Neuroscience

The emerging role of exosomes in mental disorders

(2019) Saumeh Saeedi et al.   Translational Psychiatry

Salivary Exosomes as Nanocarriers for Cancer Biomarker Delivery

(2019) Jordan Cheng et al.   Materials

Salivary alpha-synuclein in the diagnosis of Parkinson's disease and Progressive Supranuclear Palsy

(2019) Giorgio Vivacqua et al.   PARKINSONISM & RELATED DISORDERS

Ticket to a bubble ride: Cargo sorting into exosomes and extracellular vesicles

(2019) Sushma Anand et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Exosomes

(2019) D. Michiel Pegtel et al.   Annual Review of Biochemistry

Exosomes regulate neurogenesis and circuit assembly

(2019) Pranav Sharma et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Parkinson’s Disease in Women and Men: What’s the Difference?

(2019) Silvia Cerri et al.   Journal of Parkinsons Disease

Overview of Extracellular Vesicles, Their Origin, Composition, Purpose, and Methods for Exosome Isolation and Analysis

(2019) Laura M. Doyle et al.   Cells

Extracellular vesicle measurements with nanoparticle tracking analysis – An accuracy and repeatability comparison between NanoSight NS300 and ZetaView

(2019) Daniel Bachurski et al.   Journal of Extracellular Vesicles

Mapping Subpopulations of Cancer Cell-Derived Extracellular Vesicles and Particles by Nano-Flow Cytometry

(2019) Dongsic Choi et al.   ACS Nano

Concordance between the assessment of Aβ42, T-tau, and P-T181-tau in peripheral blood neuronal-derived exosomes and cerebrospinal fluid

(2019) Longfei Jia et al.   Alzheimers & Dementia

Exosome Determinants of Physiological Aging and Age-Related Neurodegenerative Diseases

(2019) Marianna D’Anca et al.   Frontiers in Aging Neuroscience

Prion-Like Mechanisms in Parkinson’s Disease

(2019) Jiangnan Ma et al.   Frontiers in Neuroscience

Neuronal exosomes in saliva of Parkinson's disease patients: A pilot study

(2019) Komal Rani et al.   PARKINSONISM & RELATED DISORDERS

A combined miRNA–piRNA signature to detect Alzheimer’s disease

(2019) Gaurav Jain et al.   Translational Psychiatry

Exploratory study on microRNA profiles from plasma-derived extracellular vesicles in Alzheimer’s disease and dementia with Lewy bodies

(2019) Ana Gámez-Valero et al.   Translational Neurodegeneration

Exosomes: Current use and future applications

(2019) Ill-Min Chung et al.   CLINICA CHIMICA ACTA

Salivary Biomarkers in Alzheimer´s Disease

(2019) Gustavo A. A Santos et al.   INTERNATIONAL JOURNAL OF MORPHOLOGY

Salivary microR‐153 and microR‐223 Levels as Potential Diagnostic Biomarkers of Idiopathic Parkinson's Disease

(2019) Marisa Cressatti et al.   MOVEMENT DISORDERS

ESCRTs in membrane sealing

(2018) Maja Radulovic et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

The emerging role of exosome-derived non-coding RNAs in cancer biology

(2018) Qing Fan et al.   CANCER LETTERS

New Technologies for Analysis of Extracellular Vesicles

(2018) Huilin Shao et al.   CHEMICAL REVIEWS

Salivary Exosomes: Emerging Roles in Systemic Disease

(2018) Yineng Han et al.   International Journal of Biological Sciences

Detection of Aggregation-Competent Tau in Neuron-Derived Extracellular Vesicles

(2018) Francesc Guix et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

In vivo evidence for the contribution of peripheral circulating inflammatory exosomes to neuroinflammation

(2018) Jing Jing Li et al.   Journal of Neuroinflammation

MicroRNA Expression Levels Are Altered in the Cerebrospinal Fluid of Patients with Young-Onset Alzheimer’s Disease

(2018) Paul M. McKeever et al.   MOLECULAR NEUROBIOLOGY

Evaluation of salivary heme oxygenase-1 as a potential biomarker of early Parkinson's disease

(2018) Wei Song et al.   MOVEMENT DISORDERS

Shedding light on the cell biology of extracellular vesicles

(2018) Guillaume van Niel et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

No association of salivary total tau concentration with Alzheimer's disease

(2018) Nicholas J. Ashton et al.   NEUROBIOLOGY OF AGING

Salivary levels of total huntingtin are elevated in Huntington’s disease patients

(2018) Jody Corey-Bloom et al.   Scientific Reports

Salivary beta amyloid protein levels are detectable and differentiate patients with Alzheimer’s disease dementia from normal controls: preliminary findings

(2018) Marwan N Sabbagh et al.   BMC Neurology

Salivary Tau Species are Potential Biomarkers of Alzheimer's Disease

(2018) Min Shi et al.   JOURNAL OF ALZHEIMERS DISEASE

Cognitive Impairment in Neurological Diseases: Lessons from Apolipoprotein E

(2018) Jiong Shi et al.   JOURNAL OF ALZHEIMERS DISEASE

Metabolomics Analyses of Saliva Detect Novel Biomarkers of Alzheimer’s Disease

(2018) Tao Huan et al.   JOURNAL OF ALZHEIMERS DISEASE

Platelet-derived extracellular vesicles in Huntington’s disease

(2018) Hélèna L. Denis et al.   JOURNAL OF NEUROLOGY

Proteomic Profiling of Exosomal Proteins for Blood-based Biomarkers in Parkinson's Disease

(2018) Yuki Kitamura et al.   NEUROSCIENCE

Quantification of brain-derived extracellular vesicles in plasma as a biomarker to diagnose Parkinson's and related diseases

(2018) Takuma Ohmichi et al.   PARKINSONISM & RELATED DISORDERS

α-Synuclein in salivary extracellular vesicles as a potential biomarker of Parkinson’s disease

(2018) Zhentang Cao et al.   NEUROSCIENCE LETTERS

Diagnostic Biomarkers of Alzheimer’s Disease as Identified in Saliva using 1H NMR-Based Metabolomics

(2017) Ali Yilmaz et al.   JOURNAL OF ALZHEIMERS DISEASE

Mutant Huntingtin Inhibits αB-Crystallin Expression and Impairs Exosome Secretion from Astrocytes

(2017) Yan Hong et al.   JOURNAL OF NEUROSCIENCE

A direct-imaging cryo-EM study of shedding extracellular vesicles from leukemic monocytes

(2017) Na'ama Koifman et al.   JOURNAL OF STRUCTURAL BIOLOGY

Extensive uptake of α-synuclein oligomers in astrocytes results in sustained intracellular deposits and mitochondrial damage

(2017) Veronica Lindström et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Cerebrospinal fluid, plasma, and saliva in the BioFIND study: Relationships among biomarkers and Parkinson's disease Features

(2017) Jennifer G. Goldman et al.   MOVEMENT DISORDERS

A clinicopathological approach to the diagnosis of dementia

(2017) Fanny M. Elahi et al.   Nature Reviews Neurology

MicroRNAs in CSF as prodromal biomarkers for Huntington disease in the PREDICT-HD study

(2017) Eric R. Reed et al.   NEUROLOGY

Bulk immunoassays for analysis of extracellular vesicles

(2017) Frank A. W. Coumans et al.   PLATELETS

Packaging and transfer of mitochondrial DNA via exosomes regulate escape from dormancy in hormonal therapy-resistant breast cancer

(2017) Pasquale Sansone et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Lipids in exosomes: Current knowledge and the way forward

(2017) Tore Skotland et al.   PROGRESS IN LIPID RESEARCH

Ultra-sensitive detection of protein biomarkers for diagnosis of Alzheimer’s disease

(2017) Hei-Nga Chan et al.   Chemical Science

Exosomes and Homeostatic Synaptic Plasticity Are Linked to Each other and to Huntington's, Parkinson's, and Other Neurodegenerative Diseases by Database-Enabled Analyses of Comprehensively Curated Datasets

(2017) James K. T. Wang et al.   Frontiers in Neuroscience

Exosome Mediated Delivery of miR-124 Promotes Neurogenesis after Ischemia

(2017) Jialei Yang et al.   Molecular Therapy-Nucleic Acids

Amyotrophic lateral sclerosis

(2017) Orla Hardiman et al.   Nature Reviews Disease Primers

Parkinson disease

(2017) Werner Poewe et al.   Nature Reviews Disease Primers

The role of exosomes in the pathogenesis of Alzheimer’ disease

(2017) Tingting Xiao et al.   Translational Neurodegeneration

Elevated LRRK2 autophosphorylation in brain-derived and peripheral exosomes in LRRK2 mutation carriers

(2017) Shijie Wang et al.   Acta Neuropathologica Communications

Amyotrophic lateral sclerosis as a protein level, non-genomic disease: Therapy with S2RM exosome released molecules

(2017) Greg Maguire   World Journal of Stem Cells

High-Resolution Single Particle Zeta Potential Characterisation of Biological Nanoparticles using Tunable Resistive Pulse Sensing

(2017) Robert Vogel et al.   Scientific Reports

Human-to-mouse prion-like propagation of mutant huntingtin protein

(2016) Iksoo Jeon et al.   ACTA NEUROPATHOLOGICA

CNS tau efflux via exosomes is likely increased in Parkinson's disease but not in Alzheimer's disease

(2016) Min Shi et al.   Alzheimers & Dementia

Exosome secretion is a key pathway for clearance of pathological TDP-43

(2016) Yohei Iguchi et al.   BRAIN

Elucidation of Exosome Migration Across the Blood–Brain Barrier Model In Vitro

(2016) Claire C. Chen et al.   Cellular and Molecular Bioengineering

Potential Transfer of Polyglutamine and CAG-Repeat RNA in Extracellular Vesicles in Huntington’s Disease: Background and Evaluation in Cell Culture

(2016) Xuan Zhang et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

α-Synuclein in Extracellular Vesicles: Functional Implications and Diagnostic Opportunities

(2016) Camilla Lööv et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Exosomes from adipose-derived stem cells ameliorate phenotype of Huntington's diseasein vitromodel

(2016) Mijung Lee et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Decreased synaptic proteins in neuronal exosomes of frontotemporal dementia and Alzheimer’s disease

(2016) Edward J. Goetzl et al.   FASEB JOURNAL

Cargo proteins of plasma astrocyte-derived exosomes in Alzheimer’s disease

(2016) Edward J. Goetzl et al.   FASEB JOURNAL

A Method for Diagnosing Alzheimer’s Disease Based on Salivary Amyloid-β Protein 42 Levels

(2016) Moonhee Lee et al.   JOURNAL OF ALZHEIMERS DISEASE

Exosomes: Tunable Nano Vehicles for Macromolecular Delivery of Transferrin and Lactoferrin to Specific Intracellular Compartment

(2016) Himanshu Malhotra et al.   Journal of Biomedical Nanotechnology

MicroRNAs in extracellular vesicles: potential cancer biomarkers

(2016) Takashi Kinoshita et al.   JOURNAL OF HUMAN GENETICS

Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes

(2016) Joanna Kowal et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Abnormal Salivary Total and Oligomeric Alpha-Synuclein in Parkinson’s Disease

(2016) Giorgio Vivacqua et al.   PLoS One

Salivary total α-synuclein, oligomeric α-synuclein and SNCA variants in Parkinson’s disease patients

(2016) Wenyan Kang et al.   Scientific Reports

High sensitivity flow cytometry of membrane vesicles

(2015) Samuel A. Stoner et al.   CYTOMETRY PART A

Prerequisites for the analysis and sorting of extracellular vesicle subpopulations by high-resolution flow cytometry

(2015) Tom Groot Kormelink et al.   CYTOMETRY PART A

Extracellular Vesicles in Alzheimer’s Disease: Friends or Foes? Focus on Aβ-Vesicle Interaction

(2015) Pooja Joshi et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Brain Health: The Importance of Recognizing Cognitive Impairment: An IAGG Consensus Conference

(2015) John E. Morley et al.   Journal of the American Medical Directors Association

Parkinson's disease

(2015) Lorraine V Kalia et al.   LANCET

MDS clinical diagnostic criteria for Parkinson's disease

(2015) Ronald B. Postuma et al.   MOVEMENT DISORDERS

The role of exosomes in peripheral nerve regeneration

(2015) PaulJ Kingham et al.   Neural Regeneration Research

Altered lysosomal proteins in neural-derived plasma exosomes in preclinical Alzheimer disease

(2015) Edward J. Goetzl et al.   NEUROLOGY

Elevated salivary protein in Parkinson's disease and salivary DJ-1 as a potential marker of disease severity

(2015) Joseph M. Masters et al.   PARKINSONISM & RELATED DISORDERS

Non-Invasive Screening for Alzheimer’s Disease by Sensing Salivary Sugar Using Drosophila Cells Expressing Gustatory Receptor (Gr5a) Immobilized on an Extended Gate Ion-Sensitive Field-Effect Transistor (EG-ISFET) Biosensor

(2015) Hui-Chong Lau et al.   PLoS One

Extracellular vesicles – Their role in the packaging and spread of misfolded proteins associated with neurodegenerative diseases

(2015) Bradley M. Coleman et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Tips and tricks for flow cytometry-based analysis and counting of microparticles

(2015) Philippe Poncelet et al.   TRANSFUSION AND APHERESIS SCIENCE

Altered microRNA profiles in cerebrospinal fluid exosome in Parkinson disease and Alzheimer disease

(2015) YaXing Gui et al.   Oncotarget

The Synaptic Function of α-Synuclein

(2015) Jacqueline Burré   Journal of Parkinsons Disease

Salivary Acetylcholinesterase Activity Is Increased in Parkinson’s Disease: A Potential Marker of Parasympathetic Dysfunction

(2015) Tatyana Fedorova et al.   Parkinsons Disease

Expanding the Repertoire of Biomarkers for Alzheimer’s Disease: Targeted and Non-targeted Approaches

(2015) Douglas Galasko   Frontiers in Neurology

Huntington disease

(2015) Gillian P. Bates et al.   Nature Reviews Disease Primers

Antibody-Based Magnetic Nanoparticle Immunoassay for Quantification of Salivary Beta-Amyloid Peptides

(2015) Chang-Beom Kim et al.   BIOPHYSICAL JOURNAL

Plasma exosomal α-synuclein is likely CNS-derived and increased in Parkinson’s disease

(2014) Min Shi et al.   ACTA NEUROPATHOLOGICA

Biogenesis, Secretion, and Intercellular Interactions of Exosomes and Other Extracellular Vesicles

(2014) Marina Colombo et al.   Annual Review of Cell and Developmental Biology

Double-stranded DNA in exosomes: a novel biomarker in cancer detection

(2014) Basant Kumar Thakur et al.   CELL RESEARCH

The Landscape of MicroRNA, Piwi-Interacting RNA, and Circular RNA in Human Saliva

(2014) J. H. Bahn et al.   CLINICAL CHEMISTRY

C9ORF72, implicated in amytrophic lateral sclerosis and frontotemporal dementia, regulates endosomal trafficking

(2014) Manal A. Farg et al.   HUMAN MOLECULAR GENETICS

Acceleration of α-Synuclein Aggregation by Exosomes

(2014) Marie Grey et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Soluble, Prefibrillar α-Synuclein Oligomers Promote Complex I-dependent, Ca2+-induced Mitochondrial Dysfunction

(2014) Eric S. Luth et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Particle size distribution of exosomes and microvesicles determined by transmission electron microscopy, flow cytometry, nanoparticle tracking analysis, and resistive pulse sensing

(2014) E. van der Pol et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

MicroRNA-193b is a regulator of amyloid precursor protein in the blood and cerebrospinal fluid derived exosomal microRNA-193b is a biomarker of Alzheimer’s disease

(2014) CHEN-GENG LIU et al.   Molecular Medicine Reports

The prevalence of Parkinson's disease: A systematic review and meta-analysis

(2014) Tamara Pringsheim et al.   MOVEMENT DISORDERS

CSF biomarkers and clinical progression of Parkinson disease

(2014) S. Hall et al.   NEUROLOGY

Multifaceted effects of oligodendroglial exosomes on neurons: impact on neuronal firing rate, signal transduction and gene regulation

(2014) D. Frohlich et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Quantitative and stoichiometric analysis of the microRNA content of exosomes

(2014) J. R. Chevillet et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Complex Ultrastructure of the Endolysosomal System

(2014) J. Klumperman et al.   Cold Spring Harbor Perspectives in Biology

Antibody-coupled monolithic silica microtips for highthroughput molecular profiling of circulating exosomes

(2014) Koji Ueda et al.   Scientific Reports

Salivary DJ-1 could be an indicator of Parkinson's disease progression

(2014) Wen-Yan Kang et al.   Frontiers in Aging Neuroscience

Limited role of free TDP-43 as a diagnostic tool in neurodegenerative diseases

(2014) Emily Feneberg et al.   Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration

Advances in non-dopaminergic treatments for Parkinson's disease

(2014) Sandy Stayte et al.   Frontiers in Neuroscience

Development of a novel cellular model of Alzheimer’s disease utilizing neurosphere cultures derived from B6C3-Tg(APPswe,PSEN1dE9)85Dbo/J embryonic mouse brain

(2014) Pankaj S Ghate et al.   SpringerPlus

Recent advances in the application of metabolomics to Alzheimer's Disease

(2013) Eugenia Trushina et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

LRRK2 secretion in exosomes is regulated by 14-3-3

(2013) K. B. Fraser et al.   HUMAN MOLECULAR GENETICS

Subthalamic neurostimulation for Parkinson's disease with early fluctuations: balancing the risks and benefits

(2013) Günther Deuschl et al.   LANCET NEUROLOGY

Multisource ascertainment of Huntington disease in Canada: Prevalence and population at risk

(2013) Emily R. Fisher et al.   MOVEMENT DISORDERS

Mutations in prion-like domains in hnRNPA2B1 and hnRNPA1 cause multisystem proteinopathy and ALS

(2013) Hong Joo Kim et al.   NATURE

Apolipoprotein E and Alzheimer disease: risk, mechanisms and therapy

(2013) Chia-Chen Liu et al.   Nature Reviews Neurology

Randomized trial of deep brain stimulation for Parkinson disease: Thirty-six-month outcomes; Turning tables: Should GPi become the preferred DBS target for parkinson disease?

(2013) E. B. Montgomery et al.   NEUROLOGY

Exosomes of BV-2 cells induced by alpha-synuclein: Important mediator of neurodegeneration in PD

(2013) Chongwang Chang et al.   NEUROSCIENCE LETTERS

Parkinson's Disease and Parkinsonism: Neuropathology

(2013) D. W. Dickson   Cold Spring Harbor Perspectives in Medicine

Neurotransmitter-Triggered Transfer of Exosomes Mediates Oligodendrocyte–Neuron Communication

(2013) Carsten Frühbeis et al.   PLOS BIOLOGY

The Complete Exosome Workflow Solution: From Isolation to Characterization of RNA Cargo

(2013) Jeoffrey Schageman et al.   Biomed Research International

Nanoparticle analysis of circulating cell-derived vesicles in ovarian cancer patients

(2012) Cicek Gercel-Taylor et al.   ANALYTICAL BIOCHEMISTRY

Cryo-electron microscopy - a primer for the non-microscopist

(2012) Jacqueline L. S. Milne et al.   FEBS Journal

Alpha-synuclein and Protein Degradation Systems: a Reciprocal Relationship

(2012) Maria Xilouri et al.   MOLECULAR NEUROBIOLOGY

Vesiclepedia: A Compendium for Extracellular Vesicles with Continuous Community Annotation

(2012) Hina Kalra et al.   PLOS BIOLOGY

Salivary α-synuclein and DJ-1: potential biomarkers for Parkinson's disease

(2011) Ivana Devic et al.   BRAIN

Characterisation of exosomes derived from human cells by nanoparticle tracking analysis and scanning electron microscopy

(2011) Viktoriya Sokolova et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

The ESCRT Pathway

(2011) William M. Henne et al.   DEVELOPMENTAL CELL

Extracellular phosphorylation of the amyloid β-peptide promotes formation of toxic aggregates during the pathogenesis of Alzheimer's disease

(2011) Sathish Kumar et al.   EMBO JOURNAL

Hsa-miR-34b is a plasma-stable microRNA that is elevated in pre-manifest Huntington's disease

(2011) Philip Michael Gaughwin et al.   HUMAN MOLECULAR GENETICS

The syndrome of cognitive impairment in amyotrophic lateral sclerosis: a population-based study

(2011) Julie Phukan et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Pathological roles of α-synuclein in neurological disorders

(2011) Kostas Vekrellis et al.   LANCET NEUROLOGY

De novo induction of amyloid-β deposition in vivo

(2011) R Morales et al.   MOLECULAR PSYCHIATRY

Treatment of Brain Inflammatory Diseases by Delivering Exosome Encapsulated Anti-inflammatory Drugs From the Nasal Region to the Brain

(2011) Xiaoying Zhuang et al.   MOLECULAR THERAPY

Sizing and phenotyping of cellular vesicles using Nanoparticle Tracking Analysis

(2011) Rebecca A. Dragovic et al.   Nanomedicine-Nanotechnology Biology and Medicine

Mutations in UBQLN2 cause dominant X-linked juvenile and adult-onset ALS and ALS/dementia

(2011) Han-Xiang Deng et al.   NATURE

Expanded GGGGCC Hexanucleotide Repeat in Noncoding Region of C9ORF72 Causes Chromosome 9p-Linked FTD and ALS

(2011) Mariely DeJesus-Hernandez et al.   NEURON

A Hexanucleotide Repeat Expansion in C9ORF72 Is the Cause of Chromosome 9p21-Linked ALS-FTD

(2011) Alan E. Renton et al.   NEURON

Metabolome in progression to Alzheimer's disease

(2011) M Orešič et al.   Translational Psychiatry

Structural-Mechanical Characterization of Nanoparticle Exosomes in Human Saliva, Using Correlative AFM, FESEM, and Force Spectroscopy

(2010) Shivani Sharma et al.   ACS Nano

Chaperone-Mediated Autophagy Markers in Parkinson Disease Brains

(2010) Lydia Alvarez-Erviti et al.   ARCHIVES OF NEUROLOGY

Deep Brain Stimulation for Parkinson Disease

(2010) Jeff M. Bronstein et al.   ARCHIVES OF NEUROLOGY

Saliva levels of Abeta1-42 as potential biomarker of Alzheimer's disease: a pilot study

(2010) Felix Bermejo-Pareja et al.   BMC Neurology

The presence of sodium dodecyl sulphate-stable Aβ dimers is strongly associated with Alzheimer-type dementia

(2010) Jessica M. Mc Donald et al.   BRAIN

Circulating MicroRNAs as Biomarkers and Potential Paracrine Mediators of Cardiovascular Disease

(2010) Shashi K. Gupta et al.   Circulation-Cardiovascular Genetics

Uptake of Huntington disease predictive testing in a complete population

(2010) PJ Morrison et al.   CLINICAL GENETICS

Flow cytometric analysis of circulating microparticles in plasma

(2010) Aaron F. Orozco et al.   CYTOMETRY PART A

Inhibition of Myelin Membrane Sheath Formation by Oligodendrocyte-derived Exosome-like Vesicles

(2010) Mostafa Bakhti et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Regulation of exosome secretion by Rab35 and its GTPase-activating proteins TBC1D10A–C

(2010) Chieh Hsu et al.   JOURNAL OF CELL BIOLOGY

Cell-Produced  -Synuclein Is Secreted in a Calcium-Dependent Manner by Exosomes and Impacts Neuronal Survival

(2010) E. Emmanouilidou et al.   JOURNAL OF NEUROSCIENCE

Release of exosomes from differentiated neurons and its regulation by synaptic glutamatergic activity

(2010) Gaelle Lachenal et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Neuropathology of Alzheimer's Disease

(2010) Daniel P. Perl   MOUNT SINAI JOURNAL OF MEDICINE

Mutations of optineurin in amyotrophic lateral sclerosis

(2010) Hirofumi Maruyama et al.   NATURE

Exome Sequencing Reveals VCP Mutations as a Cause of Familial ALS

(2010) Janel O. Johnson et al.   NEURON

Proteases and Proteolysis in Alzheimer Disease: A Multifactorial View on the Disease Process

(2010) Bart De Strooper   PHYSIOLOGICAL REVIEWS

Novel test for microparticles in platelet-rich plasma and platelet concentrates using dynamic light scattering

(2010) Yan Xu et al.   TRANSFUSION

The progression of pathology in Parkinson's disease

(2009) Glenda Margaret Halliday et al.   Annals of the New York Academy of Sciences

A proposed metabolic strategy for monitoring disease progression in Alzheimer's disease

(2009) Nicola Greenberg et al.   ELECTROPHORESIS

The second brain and Parkinson’s disease

(2009) Thibaud Lebouvier et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Atomic force microscopy: a novel approach to the detection of nanosized blood microparticles

(2009) Y. YUANA et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Non-motor symptoms of Parkinson's disease: dopaminergic pathophysiology and treatment

(2009) K Ray Chaudhuri et al.   LANCET NEUROLOGY

Rab27a and Rab27b control different steps of the exosome secretion pathway

(2009) Matias Ostrowski et al.   NATURE CELL BIOLOGY

Genome-wide association study identifies variants at CLU and CR1 associated with Alzheimer's disease

(2009) Jean-Charles Lambert et al.   NATURE GENETICS

Prion-like mechanisms in neurodegenerative diseases

(2009) Bess Frost et al.   NATURE REVIEWS NEUROSCIENCE

Biochemical and immunohistochemical analysis of an Alzheimer's disease mouse model reveals the presence of multiple cerebral Aβ assembly forms throughout life

(2009) Ganesh M. Shankar et al.   NEUROBIOLOGY OF DISEASE

Longitudinal Modeling of Age-Related Memory Decline and theAPOEε4 Effect

(2009) Richard J. Caselli et al.   NEW ENGLAND JOURNAL OF MEDICINE

Exosomes from human saliva as a source of microRNA biomarkers

(2009) A Michael et al.   ORAL DISEASES

ExoCarta: A compendium of exosomal proteins and RNA

(2009) Suresh Mathivanan et al.   PROTEOMICS

Multivesicular Endosome Biogenesis in the Absence of ESCRTs

(2009) Susanne Stuffers et al.   TRAFFIC

Microparticle sizing by dynamic light scattering in fresh-frozen plasma

(2009) A. S. Lawrie et al.   VOX SANGUINIS

A critical evaluation of the Braak staging scheme for Parkinson's disease

(2008) Robert E. Burke et al.   ANNALS OF NEUROLOGY

Exosome-Like Vesicles with Dipeptidyl Peptidase IV in Human Saliva

(2008) Yuko Ogawa et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Inhibition of γ-secretase causes increased secretion of amyloid precursor protein C-terminal fragments in association with exosomes

(2008) Robyn A. Sharples et al.   FASEB JOURNAL

Salivary Chromogranin A: Useful and Quantitative Biochemical Marker of Affective State in Patients with Amyotrophic Lateral Sclerosis

(2008) Konen Obayashi et al.   INTERNAL MEDICINE

Research in motion: the enigma of Parkinson's disease pathology spread

(2008) Patrik Brundin et al.   NATURE REVIEWS NEUROSCIENCE

α-Synuclein and Polyunsaturated Fatty Acids Promote Clathrin-Mediated Endocytosis and Synaptic Vesicle Recycling

(2008) Tziona Ben Gedalya et al.   TRAFFIC

Developing a simple laboratory test for Alzheimer's disease: measuring acetylcholinesterase in saliva - a pilot study

(2007) Paul F Boston et al.   INTERNATIONAL JOURNAL OF GERIATRIC PSYCHIATRY

Gene expression profile of the PDAPP mouse model for Alzheimer's disease with and without Apolipoprotein E

(2007) Simon P. Selwood et al.   NEUROBIOLOGY OF AGING