Proteomic Profiling of Extracellular Vesicles Derived from Cerebrospinal Fluid of Alzheimer’s Disease Patients: A Pilot Study

Apoptotic cell-derived exosomes: messages from dying cells

(2020) Ramesh Kakarla et al.   EXPERIMENTAL AND MOLECULAR MEDICINE

Assessment of separation methods for extracellular vesicles from human and mouse brain tissues and human cerebrospinal fluids

(2020) Satoshi Muraoka et al.   METHODS

Proteomic and biological profiling of extracellular vesicles from Alzheimer's disease human brain tissues

(2020) Satoshi Muraoka et al.   Alzheimers & Dementia

CNS-derived extracellular vesicles from superoxide dismutase 1 (SOD1)G93A ALS mice originate from astrocytes and neurons and carry misfolded SOD1

(2019) Judith M. Silverman et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The APMAP interactome reveals new modulators of APP processing and beta-amyloid production that are altered in Alzheimer’s disease

(2019) Hermeto Gerber et al.   Acta Neuropathologica Communications

Neuroimmune Crosstalk through Extracellular Vesicles in Health and Disease

(2019) Jean-Christophe Delpech et al.   TRENDS IN NEUROSCIENCES

Asymmetric-flow field-flow fractionation technology for exomere and small extracellular vesicle separation and characterization

(2019) Haiying Zhang et al.   Nature Protocols

Extracellular Vesicles as Diagnostics and Therapeutics for Structural Epilepsies

(2019) Jenni Karttunen et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Single-cell transcriptomic analysis of Alzheimer’s disease

(2019) Hansruedi Mathys et al.   NATURE

Microvesicles from cerebrospinal fluid of patients with Alzheimer’s disease display reduced concentrations of tau and APP protein

(2019) Philipp Spitzer et al.   Scientific Reports

Emerging roles of extracellular vesicles in neurodegenerative disorders

(2019) Yang You et al.   NEUROBIOLOGY OF DISEASE

Proteomic Profiling of Extracellular Vesicles Isolated From Cerebrospinal Fluid of Former National Football League Players at Risk for Chronic Traumatic Encephalopathy

(2019) Satoshi Muraoka et al.   Frontiers in Neuroscience

Alzheimer’s disease pathology propagation by exosomes containing toxic amyloid-beta oligomers

(2018) Maitrayee Sardar Sinha et al.   ACTA NEUROPATHOLOGICA

Longitudinal decreases in multiple cerebrospinal fluid biomarkers of neuronal injury in symptomatic late onset Alzheimer's disease

(2018) Courtney L. Sutphen et al.   Alzheimers & Dementia

CSF biomarkers of Alzheimer's disease concord with amyloid-β PET and predict clinical progression: A study of fully automated immunoassays in BioFINDER and ADNI cohorts

(2018) Oskar Hansson et al.   Alzheimers & Dementia

Comparison of membrane affinity-based method with size-exclusion chromatography for isolation of exosome-like vesicles from human plasma

(2018) Ruzena Stranska et al.   Journal of Translational Medicine

The biology of extracellular microvesicles

(2018) Alanna E. Sedgwick et al.   TRAFFIC

Pathological Proteins Are Transported by Extracellular Vesicles of Sporadic Amyotrophic Lateral Sclerosis Patients

(2018) Daisy Sproviero et al.   Frontiers in Neuroscience

Potential of Extracellular Vesicles in Neurodegenerative Diseases: Diagnostic and Therapeutic Indications

(2018) Mehrnaz Izadpanah et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Elevated CSF GAP-43 is Alzheimer's disease specific and associated with tau and amyloid pathology

(2018) Åsa Sandelius et al.   Alzheimers & Dementia

The PRIDE database and related tools and resources in 2019: improving support for quantification data

(2018) Yasset Perez-Riverol et al.   NUCLEIC ACIDS RESEARCH

Isolation of High-Purity Extracellular Vesicles by the Combination of Iodixanol Density Gradient Ultracentrifugation and Bind-Elute Chromatography From Blood Plasma

(2018) Zsófia Onódi et al.   Frontiers in Physiology

Extracellular Vesicle Biology in Alzheimer’s Disease and Related Tauopathy

(2017) Annina M. DeLeo et al.   Journal of Neuroimmune Pharmacology

Quantitative Analysis of Human Red Blood Cell Proteome

(2017) Agata H. Bryk et al.   JOURNAL OF PROTEOME RESEARCH

The release and trans-synaptic transmission of Tau via exosomes

(2017) Yipeng Wang et al.   Molecular Neurodegeneration

Brain-derived exosomes from dementia with Lewy bodies propagate α-synuclein pathology

(2017) Jennifer Ngolab et al.   Acta Neuropathologica Communications

The amyloid hypothesis of Alzheimer's disease at 25 years

(2016) Dennis J Selkoe et al.   EMBO Molecular Medicine

Focus on Extracellular Vesicles: Exosomes and Their Role in Protein Trafficking and Biomarker Potential in Alzheimer’s and Parkinson’s Disease

(2016) Laura Vella et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The pre-synaptic vesicle protein synaptotagmin is a novel biomarker for Alzheimer’s disease

(2016) Annika Öhrfelt et al.   Alzheimers Research & Therapy

A novel affinity-based method for the isolation of highly purified extracellular vesicles

(2016) Wataru Nakai et al.   Scientific Reports

Accessing to the minor proteome of red blood cells through the influence of the nanoparticle surface properties on the corona composition

(2015) Affif Zaccaria et al.   International Journal of Nanomedicine

Cell type– and brain region–resolved mouse brain proteome

(2015) Kirti Sharma et al.   NATURE NEUROSCIENCE

Depletion of microglia and inhibition of exosome synthesis halt tau propagation

(2015) Hirohide Asai et al.   NATURE NEUROSCIENCE

Arizona Study of Aging and Neurodegenerative Disorders and Brain and Body Donation Program

(2015) Thomas G. Beach et al.   NEUROPATHOLOGY

Accumulation of oxidized peroxiredoxin 2 in red blood cells and its prevention

(2015) Simone B. Bayer et al.   TRANSFUSION

Characterization of the postsynaptic protein neurogranin in paired cerebrospinal fluid and plasma samples from Alzheimer’s disease patients and healthy controls

(2015) Hlin Kvartsberg et al.   Alzheimers Research & Therapy

Alzheimer's disease

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MultiNotch MS3 Enables Accurate, Sensitive, and Multiplexed Detection of Differential Expression across Cancer Cell Line Proteomes

(2014) Graeme C. McAlister et al.   ANALYTICAL CHEMISTRY

EVpedia: a community web portal for extracellular vesicles research

(2014) D.-K. Kim et al.   BIOINFORMATICS

Expression, function, and regulation of the testis-enriched heat shock HSPA2 gene in rodents and humans

(2014) Dorota Scieglinska et al.   CELL STRESS & CHAPERONES

Benchtop isolation and characterization of functional exosomes by sequential filtration

(2014) Mitja L. Heinemann et al.   JOURNAL OF CHROMATOGRAPHY A

Microfluidic device (ExoChip) for on-chip isolation, quantification and characterization of circulating exosomes

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Hsp70 Alters Tau Function and Aggregation in an Isoform Specific Manner

(2012) Kellen Voss et al.   BIOCHEMISTRY

Reviewing reasons for the decreased CSF Abeta42 concentration in Alzheimer

(2012) Petra et al.   Frontiers in Bioscience-Landmark

Hsp70.1 and related lysosomal factors for necrotic neuronal death

(2011) Tetsumori Yamashima   JOURNAL OF NEUROCHEMISTRY

Cu, Zn-superoxide dismutase 1 (SOD1) is a novel target of Puromycin-sensitive aminopeptidase (PSA/NPEPPS): PSA/NPEPPS is a possible modifier of amyotrophic lateral sclerosis

(2011) Guijie Ren et al.   Molecular Neurodegeneration

MS3 eliminates ratio distortion in isobaric multiplexed quantitative proteomics

(2011) Lily Ting et al.   NATURE METHODS

A Tissue-Specific Atlas of Mouse Protein Phosphorylation and Expression

(2010) Edward L. Huttlin et al.   CELL

Amyloid-β and tau — a toxic pas de deux in Alzheimer's disease

(2010) Lars M. Ittner et al.   NATURE REVIEWS NEUROSCIENCE

Cerebrospinal Fluid β-Amyloid 42 and Tau Proteins as Biomarkers of Alzheimer-Type Pathologic Changes in the Brain

(2009) Tero Tapiola et al.   ARCHIVES OF NEUROLOGY

Analysis of the γ-secretase interactome and validation of its association with tetraspanin-enriched microdomains

(2009) Tomoko Wakabayashi et al.   NATURE CELL BIOLOGY

Brain-specific Proteins Decline in the Cerebrospinal Fluid of Humans with Huntington Disease

(2008) Qiaojun Fang et al.   MOLECULAR & CELLULAR PROTEOMICS