Identification of biomarkers for amyotrophic lateral sclerosis by comprehensive analysis of exosomal mRNAs in human cerebrospinal fluid

Small RNA Sequencing of Sporadic Amyotrophic Lateral Sclerosis Cerebrospinal Fluid Reveals Differentially Expressed miRNAs Related to Neural and Glial Activity

(2018) Rachel Waller et al.   Frontiers in Neuroscience

Neuronal apoptosis inhibitory protein is implicated in amyotrophic lateral sclerosis symptoms

(2018) Osamu Kano et al.   Scientific Reports

Neurofilament markers for ALS correlate with extent of upper and lower motor neuron disease

(2017) Koen Poesen et al.   NEUROLOGY

Next-generation sequencing-based small RNA profiling of cerebrospinal fluid exosomes

(2017) Yohsuke Yagi et al.   NEUROSCIENCE LETTERS

Altered nucleocytoplasmic proteome and transcriptome distributions in an in vitro model of amyotrophic lateral sclerosis

(2017) Jee-Eun Kim et al.   PLoS One

Identification of miRNAs as Potential Biomarkers in Cerebrospinal Fluid from Amyotrophic Lateral Sclerosis Patients

(2016) Michele Benigni et al.   NEUROMOLECULAR MEDICINE

ALS biomarkers for therapy development: State of the field and future directions

(2015) Michael Benatar et al.   MUSCLE & NERVE

Characterization of RNA from Exosomes and Other Extracellular Vesicles Isolated by a Novel Spin Column-Based Method

(2015) Daniel Enderle et al.   PLoS One

Biogenesis and secretion of exosomes

(2014) Joanna Kowal et al.   CURRENT OPINION IN CELL BIOLOGY

Proteomic analysis of cerebrospinal fluid extracellular vesicles: A comprehensive dataset

(2014) Davide Chiasserini et al.   Journal of Proteomics

Clinical trials in amyotrophic lateral sclerosis: why so many negative trials and how can trials be improved?

(2014) Hiroshi Mitsumoto et al.   LANCET NEUROLOGY

miRNA in Plasma Exosome is Stable under Different Storage Conditions

(2014) Qinyu Ge et al.   MOLECULES

Smart-seq2 for sensitive full-length transcriptome profiling in single cells

(2013) Simone Picelli et al.   NATURE METHODS

C9orf72 expansions are the most common genetic cause of Huntington disease phenocopies

(2013) D. J. Hensman Moss et al.   NEUROLOGY

Systemic dysregulation of TDP-43 binding microRNAs in amyotrophic lateral sclerosis

(2013) Axel Freischmidt et al.   Acta Neuropathologica Communications

CUEDC2 (CUE Domain-containing 2) and SOCS3 (Suppressors of Cytokine Signaling 3) Cooperate to Negatively Regulate Janus Kinase 1/Signal Transducers and Activators of Transcription 3 Signaling

(2011) Wei-Na Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Exosome Secretion: Molecular Mechanisms and Roles in Immune Responses

(2011) Angélique Bobrie et al.   TRAFFIC

Circulating microRNA in body fluid: a new potential biomarker for cancer diagnosis and prognosis

(2010) Nobuyoshi Kosaka et al.   CANCER SCIENCE

Release of exosomes from differentiated neurons and its regulation by synaptic glutamatergic activity

(2010) Gaelle Lachenal et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Nanostructural and Transcriptomic Analyses of Human Saliva Derived Exosomes

(2010) Viswanathan Palanisamy et al.   PLoS One

CSF neurofilament protein analysis in the differential diagnosis of ALS

(2009) Thierry S. Reijn et al.   JOURNAL OF NEUROLOGY

An Architectural Role for a Nuclear Noncoding RNA: NEAT1 RNA Is Essential for the Structure of Paraspeckles

(2009) Christine M. Clemson et al.   MOLECULAR CELL

Phosphorylated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis

(2008) Masato Hasegawa et al.   ANNALS OF NEUROLOGY