Metabolomics Analyses of Saliva Detect Novel Biomarkers of Alzheimer’s Disease

Diagnostic Biomarkers of Alzheimer’s Disease as Identified in Saliva using 1H NMR-Based Metabolomics

(2017) Ali Yilmaz et al.   JOURNAL OF ALZHEIMERS DISEASE

Metabolomics in Alzheimer’s disease: The need of complementary analytical platforms for the identification of biomarkers to unravel the underlying pathology

(2017) Raúl González-Domínguez et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

What success can teach us about failure: the plasma metabolome of older adults with superior memory and lessons for Alzheimer's disease

(2017) Mark Mapstone et al.   NEUROBIOLOGY OF AGING

Executive function performance and change in aging is predicted by apolipoprotein E , intensified by catechol-O-methyltransferase and brain-derived neurotrophic factor , and moderated by age and lifestyle

(2017) Shraddha Sapkota et al.   NEUROBIOLOGY OF AGING

Expanding the cerebrospinal fluid endopeptidome

(2017) Karl T. Hansson et al.   PROTEOMICS

Association between fatty acid metabolism in the brain and Alzheimer disease neuropathology and cognitive performance: A nontargeted metabolomic study

(2017) Stuart G. Snowden et al.   PLOS MEDICINE

Blood metabolite markers of preclinical Alzheimer's disease in two longitudinally followed cohorts of older individuals

(2016) Ramon Casanova et al.   Alzheimers & Dementia

2016 Alzheimer's disease facts and figures

(2016)   Alzheimers & Dementia

NMR analysis of the human saliva metabolome distinguishes dementia patients from matched controls

(2016) João Figueira et al.   Molecular BioSystems

Risk-reducing Apolipoprotein E and Clusterin genotypes protect against the consequences of poor vascular health on executive function performance and change in nondemented older adults

(2016) G. Peggy McFall et al.   NEUROBIOLOGY OF AGING

Neuronal histamine and cognitive symptoms in Alzheimer's disease

(2016) Armin Zlomuzica et al.   NEUROPHARMACOLOGY

Early role of vascular dysregulation on late-onset Alzheimer’s disease based on multifactorial data-driven analysis

(2016) Y. Iturria-Medina et al.   Nature Communications

Quantitative Metabolome Analysis Based on Chromatographic Peak Reconstruction in Chemical Isotope Labeling Liquid Chromatography Mass Spectrometry

(2015) Tao Huan et al.   ANALYTICAL CHEMISTRY

DnsID in MyCompoundID for Rapid Identification of Dansylated Amine- and Phenol-Containing Metabolites in LC–MS-Based Metabolomics

(2015) Tao Huan et al.   ANALYTICAL CHEMISTRY

The burden of disease in older people and implications for health policy and practice

(2015) Martin J Prince et al.   LANCET

Metabolomic research on the role of interleukin-4 in Alzheimer’s disease

(2015) Raúl González-Domínguez et al.   Metabolomics

The human saliva metabolome

(2015) Zerihun T. Dame et al.   Metabolomics

MetaboAnalyst 3.0—making metabolomics more meaningful

(2015) Jianguo Xia et al.   NUCLEIC ACIDS RESEARCH

Untargeted Metabolomic Analysis of Human Plasma Indicates Differentially Affected Polyamine and L-Arginine Metabolism in Mild Cognitive Impairment Subjects Converting to Alzheimer’s Disease

(2015) Stewart F. Graham et al.   PLoS One

Counting Missing Values in a Metabolite-Intensity Data Set for Measuring the Analytical Performance of a Metabolomics Platform

(2014) Tao Huan et al.   ANALYTICAL CHEMISTRY

IsoMS: Automated Processing of LC-MS Data Generated by a Chemical Isotope Labeling Metabolomics Platform

(2014) Ruokun Zhou et al.   ANALYTICAL CHEMISTRY

Development of a Universal Metabolome-Standard Method for Long-Term LC–MS Metabolome Profiling and Its Application for Bladder Cancer Urine-Metabolite-Biomarker Discovery

(2014) Jun Peng et al.   ANALYTICAL CHEMISTRY

Plasma Metabolite Profiles of Alzheimer’s Disease and Mild Cognitive Impairment

(2014) Gang Wang et al.   JOURNAL OF PROTEOME RESEARCH

Alzheimer’s disease drug-development pipeline: few candidates, frequent failures

(2014) Jeffrey L Cummings et al.   Alzheimers Research & Therapy

APOE and COMT polymorphisms are complementary biomarkers of status, stability, and transitions in normal aging and early mild cognitive impairment

(2014) Roger A. Dixon et al.   Frontiers in Aging Neuroscience

The Neglected Role of Histamine in Alzheimer’s Disease

(2013) Fatemeh Naddafi et al.   American Journal of Alzheimers Disease and Other Dementias

MyCompoundID: Using an Evidence-Based Metabolome Library for Metabolite Identification

(2013) Liang Li et al.   ANALYTICAL CHEMISTRY

Recent advances in the application of metabolomics to Alzheimer's Disease

(2013) Eugenia Trushina et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Metabolic signatures of human Alzheimer’s disease (AD): 1H NMR analysis of the polar metabolome of post-mortem brain tissue

(2013) Stewart F. Graham et al.   Metabolomics

Identification of Altered Metabolic Pathways in Plasma and CSF in Mild Cognitive Impairment and Alzheimer’s Disease Using Metabolomics

(2013) Eugenia Trushina et al.   PLoS One

Development of Isotope Labeling LC–MS for Human Salivary Metabolomics and Application to Profiling Metabolome Changes Associated with Mild Cognitive Impairment

(2012) Jiamin Zheng et al.   ANALYTICAL CHEMISTRY

Toward a Predictive Model of Alzheimer’s Disease Progression Using Capillary Electrophoresis–Mass Spectrometry Metabolomics

(2012) Clara Ibáñez et al.   ANALYTICAL CHEMISTRY

Determination of Total Concentration of Chemically Labeled Metabolites as a Means of Metabolome Sample Normalization and Sample Loading Optimization in Mass Spectrometry-Based Metabolomics

(2012) Yiman Wu et al.   ANALYTICAL CHEMISTRY

Sex and Gender Differences in Alzheimer's Disease: Recommendations for Future Research

(2012) Christine L. Carter et al.   JOURNAL OF WOMENS HEALTH

Translational biomarker discovery in clinical metabolomics: an introductory tutorial

(2012) Jianguo Xia et al.   Metabolomics

HMDB 3.0—The Human Metabolome Database in 2013

(2012) David S. Wishart et al.   NUCLEIC ACIDS RESEARCH

The human circadian metabolome

(2012) R. Dallmann et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Toward defining the preclinical stages of Alzheimer’s disease: Recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease

(2011) Reisa A. Sperling et al.   Alzheimers & Dementia

The diagnosis of dementia due to Alzheimer’s disease: Recommendations from the National Institute on Aging-Alzheimer’s Association workgroups on diagnostic guidelines for Alzheimer's disease

(2011) Guy M. McKhann et al.   Alzheimers & Dementia

The diagnosis of mild cognitive impairment due to Alzheimer’s disease: Recommendations from the National Institute on Aging-Alzheimer’s Association workgroups on diagnostic guidelines for Alzheimer's disease

(2011) Marilyn S. Albert et al.   Alzheimers & Dementia

Identification of a new plasma biomarker of Alzheimer's disease using metabolomics technology

(2011) Yoshiaki Sato et al.   JOURNAL OF LIPID RESEARCH

Epidemiology of Alzheimer disease

(2011) Christiane Reitz et al.   Nature Reviews Neurology

Discovery of Sexual Dimorphisms in Metabolic and Genetic Biomarkers

(2011) Kirstin Mittelstrass et al.   PLoS Genetics

Blood-based biomarkers of Alzheimer’s disease: challenging but feasible

(2010) Madhav Thambisetty et al.   Biomarkers in Medicine

Saliva: diagnostics and therapeutic perspectives

(2010) N Spielmann et al.   ORAL DISEASES

Differential12C-/13C-Isotope Dansylation Labeling and Fast Liquid Chromatography/Mass Spectrometry for Absolute and Relative Quantification of the Metabolome

(2009) Kevin Guo et al.   ANALYTICAL CHEMISTRY

Capillary electrophoresis mass spectrometry-based saliva metabolomics identified oral, breast and pancreatic cancer-specific profiles

(2009) Masahiro Sugimoto et al.   Metabolomics

Characterizing executive functioning in older special populations: From cognitively elite to cognitively impaired.

(2009) Cindy M. de Frias et al.   NEUROPSYCHOLOGY

Metabolomics: A Global Biochemical Approach to the Study of Central Nervous System Diseases

(2008) Rima Kaddurah-Daouk et al.   NEUROPSYCHOPHARMACOLOGY