Salivary Exosomes as Nanocarriers for Cancer Biomarker Delivery

Liquid Biopsy in Head and Neck Cancer: Promises and Challenges

(2018) T. Nonaka et al.   JOURNAL OF DENTAL RESEARCH

Specificities of secretion and uptake of exosomes and other extracellular vesicles for cell-to-cell communication

(2018) Mathilde Mathieu et al.   NATURE CELL BIOLOGY

Isolation of exosomes from whole blood by integrating acoustics and microfluidics

(2017) Mengxi Wu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Analysis of salivary microRNA expression profiles and identification of novel biomarkers in esophageal cancer

(2017) Jiang Du et al.   Oncology Letters

Exosomes maintain cellular homeostasis by excreting harmful DNA from cells

(2017) Akiko Takahashi et al.   Nature Communications

Circulating Tumor DNA as Biomarkers for Cancer Detection

(2017) Xiao Han et al.   GENOMICS PROTEOMICS & BIOINFORMATICS

Nanotechnologies in Cancer Treatment and Diagnosis

(2017) Stephanie A. Morris et al.   Journal of the National Comprehensive Cancer Network

Polymer-based precipitation preserves biological activities of extracellular vesicles from an endometrial cell line

(2017) Ziru Niu et al.   PLoS One

Next-Generation Sequencing of Protein-Coding and Long Non-protein-Coding RNAs in Two Types of Exosomes Derived from Human Whole Saliva

(2016) Yuko Ogawa et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Extracellular Vesicles in Cancer: Cell-to-Cell Mediators of Metastasis

(2016) Annette Becker et al.   CANCER CELL

Electrochemical detection of nucleic acids, proteins, small molecules and cells using a DNA-nanostructure-based universal biosensing platform

(2016) Meihua Lin et al.   Nature Protocols

Facile preparation of salivary extracellular vesicles for cancer proteomics

(2016) Yan Sun et al.   Scientific Reports

Evaluation of a novel saliva-based epidermal growth factor receptor mutation detection for lung cancer: A pilot study

(2016) Dan Pu et al.   Thoracic Cancer

Differential Proteomic Analysis of Human Saliva using Tandem Mass Tags Quantification for Gastric Cancer Detection

(2016) Hua Xiao et al.   Scientific Reports

Single-stranded DNA library preparation uncovers the origin and diversity of ultrashort cell-free DNA in plasma

(2016) Philip Burnham et al.   Scientific Reports

The functions of human saliva: A review sponsored by the World Workshop on Oral Medicine VI

(2015) C. Dawes et al.   ARCHIVES OF ORAL BIOLOGY

RNAPro•SAL: A device for rapid and standardized collection of saliva RNA and proteins

(2015) Samantha H. Chiang et al.   BIOTECHNIQUES

The Expression of Lung Resistance Protein in Saliva: A Novel Prognostic Indicator Protein for Carcinoma of the Breast

(2015) Nelson Wood et al.   CANCER INVESTIGATION

Circulating Tumor Cells and Circulating Tumor DNA: Challenges and Opportunities on the Path to Clinical Utility

(2015) M. Ignatiadis et al.   CLINICAL CANCER RESEARCH

Emerging treatment for advanced lung cancer withEGFRmutation

(2015) Cengiz Inal et al.   EXPERT OPINION ON EMERGING DRUGS

Testing for oncogenic molecular aberrations in cell-free DNA-based liquid biopsies in the clinic: are we there yet?

(2015) Jiri Polivka et al.   EXPERT REVIEW OF MOLECULAR DIAGNOSTICS

Exosome isolation: a microfluidic road-map

(2015) A. Liga et al.   LAB ON A CHIP

Role of Circulating Cell-Free DNA in Cancers

(2015) Raghu Aarthy et al.   Molecular Diagnosis & Therapy

Detection of somatic mutations and HPV in the saliva and plasma of patients with head and neck squamous cell carcinomas

(2015) Yuxuan Wang et al.   Science Translational Medicine

Predicting Radiotherapy Responses and Treatment Outcomes Through Analysis of Circulating Tumor DNA

(2015) Aadel A. Chaudhuri et al.   SEMINARS IN RADIATION ONCOLOGY

Shades of T790M: Intratumor Heterogeneity in EGFR-Mutant Lung Cancer

(2015) E. Ichihara et al.   Cancer Discovery

Heterogeneity Underlies the Emergence of EGFRT790 Wild-Type Clones Following Treatment of T790M-Positive Cancers with a Third-Generation EGFR Inhibitor

(2015) Z. Piotrowska et al.   Cancer Discovery

Insights into immune responses in oral cancer through proteomic analysis of saliva and salivary extracellular vesicles

(2015) Flavia V. Winck et al.   Scientific Reports

Noninvasive Saliva-basedEGFRGene Mutation Detection in Patients with Lung Cancer

(2014) Fang Wei et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

The Landscape of MicroRNA, Piwi-Interacting RNA, and Circular RNA in Human Saliva

(2014) J. H. Bahn et al.   CLINICAL CHEMISTRY

Liquid Biopsies: Genotyping Circulating Tumor DNA

(2014) Luis A. Diaz et al.   JOURNAL OF CLINICAL ONCOLOGY

Salivaomics

(2014) David T.W. Wong   JOURNAL OF THE AMERICAN DENTAL ASSOCIATION

Salivary protein factors are elevated in breast cancer patients

(2014) Mai Brooks et al.   Molecular Medicine Reports

Regulation of microRNA biogenesis

(2014) Minju Ha et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Detection of Circulating Tumor DNA in Early- and Late-Stage Human Malignancies

(2014) C. Bettegowda et al.   Science Translational Medicine

Small RNA Transcriptomes of Two Types of Exosomes in Human Whole Saliva Determined by Next Generation Sequencing

(2013) Yuko Ogawa et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Detection of exosomal biomarker by electric field-induced release and measurement (EFIRM)

(2013) Fang Wei et al.   BIOSENSORS & BIOELECTRONICS

Real-time Liquid Biopsy in Cancer Patients: Fact or Fiction?

(2013) K. Pantel et al.   CANCER RESEARCH

Discovery and Prevalidation of Salivary Extracellular microRNA Biomarkers Panel for the Noninvasive Detection of Benign and Malignant Parotid Gland Tumors

(2013) J. H. Matse et al.   CLINICAL CANCER RESEARCH

Biopsies: next-generation biospecimens for tailoring therapy

(2013) Mark Basik et al.   Nature Reviews Clinical Oncology

Extracellular vesicles: biology and emerging therapeutic opportunities

(2013) Samir EL Andaloussi et al.   NATURE REVIEWS DRUG DISCOVERY

Going with the Flow: From Circulating Tumor Cells to DNA

(2013) F.-C. Bidard et al.   Science Translational Medicine

The Secretion, Components, and Properties of Saliva

(2013) Guy H. Carpenter   Annual Review of Food Science and Technology

Method development for proteome stabilization in human saliva

(2012) Hua Xiao et al.   ANALYTICA CHIMICA ACTA

Field comparison of OraQuick® ADVANCE Rapid HIV-1/2 antibody test and two blood-based rapid HIV antibody tests in Zambia

(2012) Dalila Zachary et al.   BMC INFECTIOUS DISEASES

Prevalidation of Salivary Biomarkers for Oral Cancer Detection

(2012) D. Elashoff et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

Development of transcriptomic biomarker signature in human saliva to detect lung cancer

(2012) Lei Zhang et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

The Human Salivary RNA Transcriptome Revealed by Massively Parallel Sequencing

(2012) N. Spielmann et al.   CLINICAL CHEMISTRY

Saliva proteomics as an emerging, non-invasive tool to study livestock physiology, nutrition and diseases

(2012) Elsa Lamy et al.   Journal of Proteomics

Intratumor Heterogeneity and Branched Evolution Revealed by Multiregion Sequencing

(2012) Marco Gerlinger et al.   NEW ENGLAND JOURNAL OF MEDICINE

The Majority of MicroRNAs Detectable in Serum and Saliva Is Concentrated in Exosomes

(2012) Alessia Gallo et al.   PLoS One

Salivary biomarker development using genomic, proteomic and metabolomic approaches

(2012) Nicolai J Bonne et al.   Genome Medicine

Vesiclepedia: A Compendium for Extracellular Vesicles with Continuous Community Annotation

(2012) Hina Kalra et al.   PLOS BIOLOGY

Salivary transcriptomic biomarkers for detection of ovarian cancer: for serous papillary adenocarcinoma

(2011) Yu-Hsiang Lee et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Human saliva, plasma and breast milk exosomes contain RNA: uptake by macrophages

(2011) Cecilia Lässer et al.   Journal of Translational Medicine

Quantitative Nanostructural and Single-Molecule Force Spectroscopy Biomolecular Analysis of Human-Saliva-Derived Exosomes

(2011) Shivani Sharma et al.   LANGMUIR

Proteomic Analysis of Human Saliva From Lung Cancer Patients Using Two-Dimensional Difference Gel Electrophoresis and Mass Spectrometry

(2011) Hua Xiao et al.   MOLECULAR & CELLULAR PROTEOMICS

Defining Salivary Biomarkers Using Mass Spectrometry-Based Proteomics: A Systematic Review

(2011) Sandra K. Al-Tarawneh et al.   OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY

Discovery and Preclinical Validation of Salivary Transcriptomic and Proteomic Biomarkers for the Non-Invasive Detection of Breast Cancer

(2011) Lei Zhang et al.   PLoS One

Structural-Mechanical Characterization of Nanoparticle Exosomes in Human Saliva, Using Correlative AFM, FESEM, and Force Spectroscopy

(2010) Shivani Sharma et al.   ACS Nano

Saliva Ontology: An ontology-based framework for a Salivaomics Knowledge Base

(2010) Jiye Ai et al.   BMC BIOINFORMATICS

Cell-Free Nucleic Acids Circulating in the Plasma of Colorectal Cancer Patients Induce the Oncogenic Transformation of Susceptible Cultured Cells

(2010) D. C. Garcia-Olmo et al.   CANCER RESEARCH

Adenosine deaminase in saliva as a diagnostic marker of squamous cell carcinoma of tongue

(2010) Balwant Rai et al.   Clinical Oral Investigations

Salivary cortisol or cortisone?

(2010) Hershel Raff et al.   Nature Reviews Endocrinology

Nanostructural and Transcriptomic Analyses of Human Saliva Derived Exosomes

(2010) Viswanathan Palanisamy et al.   PLoS One

Nanotechnology for Early Cancer Detection

(2010) Young-Eun Choi et al.   SENSORS

In Vivo Imaging in Cancer

(2010) J. Condeelis et al.   Cold Spring Harbor Perspectives in Biology

Use of Saliva-Based Nano-Biochip Tests for Acute Myocardial Infarction at the Point of Care: A Feasibility Study

(2009) P. N. Floriano et al.   CLINICAL CHEMISTRY

Exosomes – vesicular carriers for intercellular communication

(2009) Mikael Simons et al.   CURRENT OPINION IN CELL BIOLOGY

Salivary Transcriptomic Biomarkers for Detection of Resectable Pancreatic Cancer

(2009) Lei Zhang et al.   GASTROENTEROLOGY

A Dynamic Range Compression and Three-Dimensional Peptide Fractionation Analysis Platform Expands Proteome Coverage and the Diagnostic Potential of Whole Saliva

(2009) Sricharan Bandhakavi et al.   JOURNAL OF PROTEOME RESEARCH

Programming the detection limits of biosensors through controlled nanostructuring

(2009) Leyla Soleymani et al.   Nature Nanotechnology

Exosomes from human saliva as a source of microRNA biomarkers

(2009) A Michael et al.   ORAL DISEASES

Diagnostic model of saliva protein finger print analysis of patients with gastric cancer

(2009) Zheng-Zhi Wu et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Exosome-Like Vesicles with Dipeptidyl Peptidase IV in Human Saliva

(2008) Yuko Ogawa et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Salivary Proteomics for Oral Cancer Biomarker Discovery

(2008) S. Hu et al.   CLINICAL CANCER RESEARCH

Current Status of Salivary Hormone Analysis

(2008) M. Groschl   CLINICAL CHEMISTRY

Analysis of the saliva proteome from patients with head and neck squamous cell carcinoma reveals differences in abundance levels of proteins associated with tumour progression and metastasis

(2008) Paul Dowling et al.   Journal of Proteomics

Imaging in the era of molecular oncology

(2008) Ralph Weissleder et al.   NATURE

Diagnostic accuracy of NicAlert cotinine test strips in saliva for verifying smoking status

(2008) Fiona Cooke et al.   NICOTINE & TOBACCO RESEARCH

Systematic comparison of the human saliva and plasma proteomes

(2008) Weihong Yan et al.   Proteomics Clinical Applications

Apoptosis: controlled demolition at the cellular level

(2007) Rebecca C. Taylor et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY