Unraveling the regulatory role of endoplasmic-reticulum-associated degradation in tumor immunity
Published 2020 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Unraveling the regulatory role of endoplasmic-reticulum-associated degradation in tumor immunity
Authors
Keywords
-
Journal
CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY
Volume -, Issue -, Pages 1-32
Publisher
Informa UK Limited
Online
2020-07-07
DOI
10.1080/10409238.2020.1784085
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Targeting FROUNT with disulfiram suppresses macrophage accumulation and its tumor-promoting properties
- (2020) Yuya Terashima et al. Nature Communications
- ER stress-induced mediator C/EBP homologous protein thwarts effector T cell activity in tumors through T-bet repression
- (2019) Yu Cao et al. Nature Communications
- Functional Roles of the IgM Fc Receptor in the Immune System
- (2019) Hiromi Kubagawa et al. Frontiers in Immunology
- ATF6α Activation Enhances Survival against Chemotherapy and Serves as a Prognostic Indicator in Osteosarcoma
- (2019) Suma Yarapureddy et al. NEOPLASIA
- EPHB4 inhibition activates ER stress to promote immunogenic cell death of prostate cancer cells
- (2019) Vinay Sagar et al. Cell Death & Disease
- Characterization of WDR20: A new regulator of the ERAD machinery
- (2018) Lin-Gao Ju et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Reduced mannosidase MAN1A1 expression leads to aberrant N-glycosylation and impaired survival in breast cancer
- (2018) Karen Legler et al. BRITISH JOURNAL OF CANCER
- Osimertinib resistance in non-small cell lung cancer: Mechanisms and therapeutic strategies
- (2018) Zheng-Hai Tang et al. CANCER LETTERS
- Immunogenic chemotherapy: Dose and schedule dependence and combination with immunotherapy
- (2018) Junjie Wu et al. CANCER LETTERS
- Interactions between EGFR and PD-1/PD-L1 pathway: Implications for treatment of NSCLC
- (2018) Xue Li et al. CANCER LETTERS
- eIF2α phosphorylation is pathognomonic for immunogenic cell death
- (2018) Lucillia Bezu et al. CELL DEATH AND DIFFERENTIATION
- Low-Protein Diet Induces IRE1α-Dependent Anticancer Immunosurveillance
- (2018) Camila Rubio-Patiño et al. Cell Metabolism
- ER-localized protein-Herpud1 is a new mediator of IL-4-induced macrophage polarization and migration
- (2018) Yiman Li et al. EXPERIMENTAL CELL RESEARCH
- ER-resident protein 46 (ERp46) triggers the mannose-trimming activity of ER degradation–enhancing α-mannosidase–like protein 3 (EDEM3)
- (2018) Shangyu Yu et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- UFD1 contributes to MYC-mediated leukemia aggressiveness through suppression of the proapoptotic unfolded protein response
- (2018) LN Huiting et al. LEUKEMIA
- Dynamic changes in complexes of IRE1α, PERK, and ATF6α during endoplasmic reticulum stress
- (2018) Arunkumar Sundaram et al. MOLECULAR BIOLOGY OF THE CELL
- The CDK4/6 Inhibitor Abemaciclib Induces a T Cell Inflamed Tumor Microenvironment and Enhances the Efficacy of PD-L1 Checkpoint Blockade
- (2018) David A. Schaer et al. Cell Reports
- Current Concepts of Antigen Cross-Presentation
- (2018) Maria Embgenbroich et al. Frontiers in Immunology
- PKR and GCN2 stress kinases promote an ER stress-independent eIF2α phosphorylation responsible for calreticulin exposure in melanoma cells
- (2018) Paola Giglio et al. OncoImmunology
- ERADicate Tumor Progression with Metformin
- (2018) Lena-Sophie Dreher et al. MOLECULAR CELL
- Metformin Promotes Antitumor Immunity via Endoplasmic-Reticulum-Associated Degradation of PD-L1
- (2018) Jong-Ho Cha et al. MOLECULAR CELL
- Biological Consequences of Major Histocompatibility Class-II Expression by Tumor Cells in Cancer
- (2018) Margaret L Axelrod et al. CLINICAL CANCER RESEARCH
- Upregulation of HRD1 promotes cell migration and invasion in colon cancer
- (2018) Xueming Tan et al. MOLECULAR AND CELLULAR BIOCHEMISTRY
- Monoclonal antibodies in cancer immunotherapy
- (2018) Ilgin Kimiz-Gebologlu et al. MOLECULAR BIOLOGY REPORTS
- Endoplasmic reticulum stress induced LOX-1+ CD15+ polymorphonuclear myeloid-derived suppressor cells in hepatocellular carcinoma
- (2017) Jiang Nan et al. IMMUNOLOGY
- Molecular-Targeted Therapies for Epidermal Growth Factor Receptor and Its Resistance Mechanisms
- (2017) Toshimitsu Yamaoka et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- ER-associated degradation is required for vasopressin prohormone processing and systemic water homeostasis
- (2017) Guojun Shi et al. JOURNAL OF CLINICAL INVESTIGATION
- Critical role for Sec22b-dependent antigen cross-presentation in antitumor immunity
- (2017) Andrés Alloatti et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Alcohol-abuse drug disulfiram targets cancer via p97 segregase adaptor NPL4
- (2017) Zdenek Skrott et al. NATURE
- CDK4/6 inhibition triggers anti-tumour immunity
- (2017) Shom Goel et al. NATURE
- Cryo-EM structure of the protein-conducting ERAD channel Hrd1 in complex with Hrd3
- (2017) Stefan Schoebel et al. NATURE
- Durvalumab after Chemoradiotherapy in Stage III Non–Small-Cell Lung Cancer
- (2017) Scott J. Antonia et al. NEW ENGLAND JOURNAL OF MEDICINE
- Overexpression of Derlin 3 is associated with malignant phenotype of breast cancer cells
- (2017) Masahiro Shibata et al. ONCOLOGY REPORTS
- Autophagy-related protein Vps34 controls the homeostasis and function of antigen cross-presenting CD8α+dendritic cells
- (2017) Vrajesh V. Parekh et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Sec61 blockade by mycolactone inhibits antigen cross-presentation independently of endosome-to-cytosol export
- (2017) Jeff E. Grotzke et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- CDK4/6 Inhibition Augments Antitumor Immunity by Enhancing T-cell Activation
- (2017) Jiehui Deng et al. Cancer Discovery
- Endoplasmic reticulum stress-mediated membrane expression of CRT/ERp57 induces immunogenic apoptosis in drug-resistant endometrial cancer cells
- (2017) Qin Xu et al. Oncotarget
- Derlin-1 overexpression confers poor prognosis in muscle invasive bladder cancer and contributes to chemoresistance and invasion through PI3K/AKT and ERK/MMP signaling
- (2017) Qianze Dong et al. Oncotarget
- Context-dependent miR-204 and miR-211 affect the biological properties of amelanotic and melanotic melanoma cells
- (2017) Marianna Vitiello et al. Oncotarget
- Immune Effector Recovery in Chronic Myeloid Leukemia and Treatment-Free Remission
- (2017) Amy Hughes et al. Frontiers in Immunology
- Accomplices of the Hypoxic Tumor Microenvironment Compromising Antitumor Immunity: Adenosine, Lactate, Acidosis, Vascular Endothelial Growth Factor, Potassium Ions, and Phosphatidylserine
- (2017) Peter Vaupel et al. Frontiers in Immunology
- Trial watch: Immunogenic cell death induction by anticancer chemotherapeutics
- (2017) Abhishek D. Garg et al. OncoImmunology
- CTLA-4 and PD-1 Pathways
- (2016) Elizabeth I. Buchbinder et al. AMERICAN JOURNAL OF CLINICAL ONCOLOGY-CANCER CLINICAL TRIALS
- The effect of cyclophosphamide on the immune system: implications for clinical cancer therapy
- (2016) Martina Ahlmann et al. CANCER CHEMOTHERAPY AND PHARMACOLOGY
- Calreticulin Expression in Human Non–Small Cell Lung Cancers Correlates with Increased Accumulation of Antitumor Immune Cells and Favorable Prognosis
- (2016) Jitka Fucikova et al. CANCER RESEARCH
- Autoubiquitination of the Hrd1 Ligase Triggers Protein Retrotranslocation in ERAD
- (2016) Ryan D. Baldridge et al. CELL
- Turning tumour cells into antigen presenting cells: The next step to improve cancer immunotherapy?
- (2016) Marie de Charette et al. EUROPEAN JOURNAL OF CANCER
- Anti-GD2 mAbs and next-generation mAb-based agents for cancer therapy
- (2016) Zulmarie Perez Horta et al. Immunotherapy
- Cell autonomous or systemic EGFR blockade alters the immune-environment in squamous cell carcinomas
- (2016) Francesca Mascia et al. INTERNATIONAL JOURNAL OF CANCER
- Long-Peptide Cross-Presentation by Human Dendritic Cells Occurs in Vacuoles by Peptide Exchange on Nascent MHC Class I Molecules
- (2016) Wenbin Ma et al. JOURNAL OF IMMUNOLOGY
- The Grp170 nucleotide exchange factor executes a key role during ERAD of cellular misfolded clients
- (2016) Takamasa Inoue et al. MOLECULAR BIOLOGY OF THE CELL
- Endoplasmic reticulum-resident E3 ubiquitin ligase Hrd1 controls B-cell immunity through degradation of the death receptor CD95/Fas
- (2016) Sinyi Kong et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- TLR and NLRP3 inflammasome-dependent innate immune responses to tumor-derived autophagosomes (DRibbles)
- (2016) Y Xing et al. Cell Death & Disease
- The ER membrane-anchored ubiquitin ligase Hrd1 is a positive regulator of T-cell immunity
- (2016) Yuanming Xu et al. Nature Communications
- The Sel1L-Hrd1 Endoplasmic Reticulum-Associated Degradation Complex Manages a Key Checkpoint in B Cell Development
- (2016) Yewei Ji et al. Cell Reports
- STAT3 and STAT6 Signaling Pathways Synergize to Promote Cathepsin Secretion from Macrophages via IRE1α Activation
- (2016) Dongyao Yan et al. Cell Reports
- Caspase-2 and oxidative stress underlie the immunogenic potential of high hydrostatic pressure-induced cancer cell death
- (2016) Irena Moserova et al. OncoImmunology
- Etoposide Induces Apoptosis in Activated Human Hepatic Stellate Cells via ER Stress
- (2016) Chen Wang et al. Scientific Reports
- Endoplasmic Reticulum Stress in Immunity
- (2015) Sarah E. Bettigole et al. Annual Review of Immunology
- The Role of Endoplasmic Reticulum Stress in Human Pathology
- (2015) Scott A. Oakes et al. Annual Review of Pathology-Mechanisms of Disease
- Targeting the AAA ATPase p97 as an Approach to Treat Cancer through Disruption of Protein Homeostasis
- (2015) Daniel J. Anderson et al. CANCER CELL
- Regulation of Glutamine Carrier Proteins by RNF5 Determines Breast Cancer Response to ER Stress-Inducing Chemotherapies
- (2015) Young Joo Jeon et al. CANCER CELL
- ER Stress Sensor XBP1 Controls Anti-tumor Immunity by Disrupting Dendritic Cell Homeostasis
- (2015) Juan R. Cubillos-Ruiz et al. CELL
- Glucosidase II and MRH-Domain Containing Proteins in the Secretory Pathway
- (2015) Cecilia D’Alessio et al. CURRENT PROTEIN & PEPTIDE SCIENCE
- The Translocon Protein Sec61 Mediates Antigen Transport from Endosomes in the Cytosol for Cross-Presentation to CD8+ T Cells
- (2015) Matthias Zehner et al. IMMUNITY
- Toxicities of Immunotherapy for the Practitioner
- (2015) Jeffrey S. Weber et al. JOURNAL OF CLINICAL ONCOLOGY
- Derlin-1 is overexpressed in human colon cancer and promotes cancer cell proliferation
- (2015) Xueming Tan et al. MOLECULAR AND CELLULAR BIOCHEMISTRY
- gp78 functions downstream of Hrd1 to promote degradation of misfolded proteins of the endoplasmic reticulum
- (2015) Ting Zhang et al. MOLECULAR BIOLOGY OF THE CELL
- Are ERAD components involved in cross-presentation?
- (2015) Jeff E. Grotzke et al. MOLECULAR IMMUNOLOGY
- IRE1α is an endogenous substrate of endoplasmic-reticulum-associated degradation
- (2015) Shengyi Sun et al. NATURE CELL BIOLOGY
- Glycosylation-directed quality control of protein folding
- (2015) Chengchao Xu et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Deacetylation of HSPA5 by HDAC6 leads to GP78-mediated HSPA5 ubiquitination at K447 and suppresses metastasis of breast cancer
- (2015) Y-W Chang et al. ONCOGENE
- The Evolving Role of Immune Checkpoint Inhibitors in Cancer Treatment
- (2015) G. K. Pennock et al. ONCOLOGIST
- The PERKs of damage-associated molecular patterns mediating cancer immunogenicity: From sensor to the plasma membrane and beyond
- (2015) A.R. van Vliet et al. SEMINARS IN CANCER BIOLOGY
- Genetic Inhibition Of The Ubiquitin Ligase Rnf5 Attenuates Phenotypes Associated To F508del Cystic Fibrosis Mutation
- (2015) Valeria Tomati et al. Scientific Reports
- Targeting abnormal ER stress responses in tumors: A new approach to cancer immunotherapy
- (2015) Juan R. Cubillos-Ruiz et al. OncoImmunology
- Gp78, an E3 Ubiquitin Ligase Acts as a Gatekeeper Suppressing Nonalcoholic Steatohepatitis (NASH) and Liver Cancer
- (2015) Tianpeng Zhang et al. PLoS One
- Elevated endoplasmic reticulum stress reinforced immunosuppression in the tumor microenvironment via myeloid-derived suppressor cells
- (2015) Bo-Ra Lee et al. Oncotarget
- A novel long non-coding RNA ENST00000480739 suppresses tumour cell invasion by regulating OS-9 and HIF-1α in pancreatic ductal adenocarcinoma
- (2014) Y-W Sun et al. BRITISH JOURNAL OF CANCER
- ER Stress Cooperates with Hypernutrition to Trigger TNF-Dependent Spontaneous HCC Development
- (2014) Hayato Nakagawa et al. CANCER CELL
- The ER-Associated Degradation Adaptor Protein Sel1L Regulates LPL Secretion and Lipid Metabolism
- (2014) Haibo Sha et al. Cell Metabolism
- UPR decreases CD226 ligand CD155 expression and sensitivity to NK cell-mediated cytotoxicity in hepatoma cells
- (2014) Jiuyu Gong et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- The Stress-Response Sensor Chop Regulates the Function and Accumulation of Myeloid-Derived Suppressor Cells in Tumors
- (2014) Paul T. Thevenot et al. IMMUNITY
- EDEM2 initiates mammalian glycoprotein ERAD by catalyzing the first mannose trimming step
- (2014) Satoshi Ninagawa et al. JOURNAL OF CELL BIOLOGY
- ER-associated degradation: Protein quality control and beyond
- (2014) Annamaria Ruggiano et al. JOURNAL OF CELL BIOLOGY
- Targeting ER stress–induced autophagy overcomes BRAF inhibitor resistance in melanoma
- (2014) Xiao-Hong Ma et al. JOURNAL OF CLINICAL INVESTIGATION
- ER stress regulates myeloid-derived suppressor cell fate through TRAIL-R–mediated apoptosis
- (2014) Thomas Condamine et al. JOURNAL OF CLINICAL INVESTIGATION
- Hrd1-mediated BLIMP-1 ubiquitination promotes dendritic cell MHCII expression for CD4 T cell priming during inflammation
- (2014) Heeyoung Yang et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Imatinib Mesylate Inhibits CD4+CD25+ Regulatory T Cell Activity and Enhances Active Immunotherapy against BCR-ABL- Tumors
- (2014) N. Larmonier et al. JOURNAL OF IMMUNOLOGY
- ERP57 Membrane Translocation Dictates the Immunogenicity of Tumor Cell Death by Controlling the Membrane Translocation of Calreticulin
- (2014) M. Obeid JOURNAL OF IMMUNOLOGY
- The Role of Macrophage Polarization in Infectious and Inflammatory Diseases
- (2014) Adam C. Labonte et al. MOLECULES AND CELLS
- Emerging functions of the unfolded protein response in immunity
- (2014) Sophie Janssens et al. NATURE IMMUNOLOGY
- Cleaning up in the endoplasmic reticulum: ubiquitin in charge
- (2014) John C Christianson et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Cross-Presentation of Synthetic Long Peptides by Human Dendritic Cells: A Process Dependent on ERAD Component p97/VCP but Not sec61 and/or Derlin-1
- (2014) Jérémie Ménager et al. PLoS One
- EDEM2 and OS-9 Are Required for ER-Associated Degradation of Non-Glycosylated Sonic Hedgehog
- (2014) Hsiang-Yun Tang et al. PLoS One
- TMEM129 is a Derlin-1 associated ERAD E3 ligase essential for virus-induced degradation of MHC-I
- (2014) D. J. H. van den Boomen et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Sel1L is indispensable for mammalian endoplasmic reticulum-associated degradation, endoplasmic reticulum homeostasis, and survival
- (2014) Shengyi Sun et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A high-coverage shRNA screen identifies TMEM129 as an E3 ligase involved in ER-associated protein degradation
- (2014) Michael L. van de Weijer et al. Nature Communications
- Endoplasmic Reticulum Degradation-Enhancing α-Mannosidase-like Protein 1 Targets Misfolded HLA-B27 Dimers for Endoplasmic Reticulum-Associated Degradation
- (2014) David B. Guiliano et al. Arthritis & Rheumatology
- Regulation of Metastasis by microRNAs in Ovarian Cancer
- (2014) Yongchao Wang et al. Frontiers in Oncology
- Macrophage Polarization at the Crossroad Between HIV-1 Infection and Cancer Development
- (2013) Massimo Alfano et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- Multimodal immunogenic cancer cell death as a consequence of anticancer cytotoxic treatments
- (2013) H Inoue et al. CELL DEATH AND DIFFERENTIATION
- Cetuximab-Activated Natural Killer and Dendritic Cells Collaborate to Trigger Tumor Antigen-Specific T-cell Immunity in Head and Neck Cancer Patients
- (2013) R. M. Srivastava et al. CLINICAL CANCER RESEARCH
- Crosstalk between ER stress and immunogenic cell death
- (2013) Oliver Kepp et al. CYTOKINE & GROWTH FACTOR REVIEWS
- ER stress transcription factor Xbp1 suppresses intestinal tumorigenesis and directs intestinal stem cells
- (2013) Lukas Niederreiter et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Enhanced Endoplasmic Reticulum Entry of Tumor Antigen Is Crucial for Cross-Presentation Induced by Dendritic Cell-Targeted Vaccination
- (2013) H. Wang et al. JOURNAL OF IMMUNOLOGY
- MHC Class I Antigen Processing and Presenting Machinery: Organization, Function, and Defects in Tumor Cells
- (2013) P. Leone et al. JNCI-Journal of the National Cancer Institute
- Influence of tumour micro-environment heterogeneity on therapeutic response
- (2013) Melissa R. Junttila et al. NATURE
- Der1 promotes movement of misfolded proteins through the endoplasmic reticulum membrane
- (2013) Martin Mehnert et al. NATURE CELL BIOLOGY
- Covalent and allosteric inhibitors of the ATPase VCP/p97 induce cancer cell death
- (2013) Paola Magnaghi et al. Nature Chemical Biology
- Microenvironmental regulation of tumor progression and metastasis
- (2013) Daniela F Quail et al. NATURE MEDICINE
- Endoplasmic Reticulum Stress Signaling Is Involved in Mitomycin C(MMC)-Induced Apoptosis in Human Fibroblasts via PERK Pathway
- (2013) Kun Shi et al. PLoS One
- Bleomycin Exerts Ambivalent Antitumor Immune Effect by Triggering Both Immunogenic Cell Death and Proliferation of Regulatory T Cells
- (2013) Hélène Bugaut et al. PLoS One
- MHC Class I Antigen Presentation of DRiP-Derived Peptides from a Model Antigen Is Not Dependent on the AAA ATPase p97
- (2013) Amy L. Palmer et al. PLoS One
- Establishment of an In Vitro Transport Assay That Reveals Mechanistic Differences in Cytosolic Events Controlling Cholera Toxin and T-Cell Receptor α Retro-Translocation
- (2013) Paul Moore et al. PLoS One
- MHC class I molecules are preferentially ubiquitinated on endoplasmic reticulum luminal residues during HRD1 ubiquitin E3 ligase-mediated dislocation
- (2013) M. L. Burr et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Dendritic Cells: Master Regulators of the Immune Response
- (2013) I. Mellman Cancer Immunology Research
- Targeting endoplasmic reticulum signaling pathways in cancer
- (2012) Fabio Martinon ACTA ONCOLOGICA
- p97 complexes as signal integration hubs
- (2012) Hemmo Meyer BMC BIOLOGY
- B-Cell Cross-Presentation of Autologous Antigen Precipitates Diabetes
- (2012) E. Marino et al. DIABETES
- A novel pathway combining calreticulin exposure and ATP secretion in immunogenic cancer cell death
- (2012) Abhishek D Garg et al. EMBO JOURNAL
- Programmed cell death 1 forms negative costimulatory microclusters that directly inhibit T cell receptor signaling by recruiting phosphatase SHP2
- (2012) Tadashi Yokosuka et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Unassembled CD147 is an endogenous endoplasmic reticulum–associated degradation substrate
- (2012) Ryan E. Tyler et al. MOLECULAR BIOLOGY OF THE CELL
- Derlin-1 and UBXD8 are engaged in dislocation and degradation of lipidated ApoB-100 at lipid droplets
- (2012) Michitaka Suzuki et al. MOLECULAR BIOLOGY OF THE CELL
- Ancient ubiquitous protein-1 mediates sterol-induced ubiquitination of 3-hydroxy-3-methylglutaryl CoA reductase in lipid droplet–associated endoplasmic reticulum membranes
- (2012) Youngah Jo et al. MOLECULAR BIOLOGY OF THE CELL
- Emerging functions of the VCP/p97 AAA-ATPase in the ubiquitin system
- (2012) Hemmo Meyer et al. NATURE CELL BIOLOGY
- The Delicate Balance Between Secreted Protein Folding and Endoplasmic Reticulum-Associated Degradation in Human Physiology
- (2012) Christopher J. Guerriero et al. PHYSIOLOGICAL REVIEWS
- Cell-Extrinsic Effects of Tumor ER Stress Imprint Myeloid Dendritic Cells and Impair CD8+ T Cell Priming
- (2012) Navin R. Mahadevan et al. PLoS One
- SGTA Recognizes a Noncanonical Ubiquitin-like Domain in the Bag6-Ubl4A-Trc35 Complex to Promote Endoplasmic Reticulum-Associated Degradation
- (2012) Yue Xu et al. Cell Reports
- How to improve the immunogenicity of chemotherapy and radiotherapy
- (2011) Yuting Ma et al. CANCER AND METASTASIS REVIEWS
- Human Tumor Cells Killed by Anthracyclines Induce a Tumor-Specific Immune Response
- (2011) J. Fucikova et al. CANCER RESEARCH
- Rhomboid Family Pseudoproteases Use the ER Quality Control Machinery to Regulate Intercellular Signaling
- (2011) Markus Zettl et al. CELL
- Proteostasis regulation at the endoplasmic reticulum: a new perturbation site for targeted cancer therapy
- (2011) Yanfen Liu et al. CELL RESEARCH
- Tumor-Derived Autophagosome Vaccine: Mechanism of Cross-Presentation and Therapeutic Efficacy
- (2011) Y. Li et al. CLINICAL CANCER RESEARCH
- Cyclosporine A suppresses immunoglobulin G biosynthesis via inhibition of cyclophilin B in murine hybridomas and B cells
- (2011) Jisun Lee et al. INTERNATIONAL IMMUNOPHARMACOLOGY
- The E3 Ligase Smurf1 Regulates Wolfram Syndrome Protein Stability at the Endoplasmic Reticulum
- (2011) Xing Guo et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The Unfolded Protein Response (UPR)-activated Transcription Factor X-box-binding Protein 1 (XBP1) Induces MicroRNA-346 Expression That Targets the Human Antigen Peptide Transporter 1 (TAP1) mRNA and Governs Immune Regulatory Genes
- (2011) Rafal Bartoszewski et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Tolerogenic function of Blimp-1 in dendritic cells
- (2011) Sun Jung Kim et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Skin-Depigmenting Agent Monobenzone Induces Potent T-Cell Autoimmunity toward Pigmented Cells by Tyrosinase Haptenation and Melanosome Autophagy
- (2011) Jasper G. van den Boorn et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- Immunomodulatory effects of anti-angiogenic drugs
- (2011) A Heine et al. LEUKEMIA
- Dual Regulation of the Transcriptional Activity of Nrf1 by -TrCP- and Hrd1-Dependent Degradation Mechanisms
- (2011) Y. Tsuchiya et al. MOLECULAR AND CELLULAR BIOLOGY
- Yos9p assists in the degradation of certain nonglycosylated proteins from the endoplasmic reticulum
- (2011) Laura A. Jaenicke et al. MOLECULAR BIOLOGY OF THE CELL
- A Ubiquitin Ligase-Associated Chaperone Holdase Maintains Polypeptides in Soluble States for Proteasome Degradation
- (2011) Qiuyan Wang et al. MOLECULAR CELL
- Defining human ERAD networks through an integrative mapping strategy
- (2011) John C. Christianson et al. NATURE CELL BIOLOGY
- Derlin-1 is a rhomboid pseudoprotease required for the dislocation of mutant α-1 antitrypsin from the endoplasmic reticulum
- (2011) Ethan J Greenblatt et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Transmission of endoplasmic reticulum stress and pro-inflammation from tumor cells to myeloid cells
- (2011) N. R. Mahadevan et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- HRD1 and UBE2J1 target misfolded MHC class I heavy chains for endoplasmic reticulum-associated degradation
- (2011) Marian L. Burr et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Mannose receptor polyubiquitination regulates endosomal recruitment of p97 and cytosolic antigen translocation for cross-presentation
- (2011) M. Zehner et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The Unfolded Protein Response: From Stress Pathway to Homeostatic Regulation
- (2011) P. Walter et al. SCIENCE
- Unfolded Proteins Are Ire1-Activating Ligands That Directly Induce the Unfolded Protein Response
- (2011) B. M. Gardner et al. SCIENCE
- Cellular Strategies of Protein Quality Control
- (2011) B. Chen et al. Cold Spring Harbor Perspectives in Biology
- Tetra-glutamic acid residues adjacent to Lys248 in HMG-CoA reductase are critical for the ubiquitination mediated by gp78 and UBE2G2
- (2010) Honghua Miao et al. ACTA BIOCHIMICA ET BIOPHYSICA SINICA
- SCFFbx2-E3-ligase-mediated degradation of BACE1 attenuates Alzheimer’s disease amyloidosis and improves synaptic function
- (2010) Bing Gong et al. AGING CELL
- Cyclophosphamide Synergizes with Type I Interferons through Systemic Dendritic Cell Reactivation and Induction of Immunogenic Tumor Apoptosis
- (2010) G. Schiavoni et al. CANCER RESEARCH
- Endoplasmic Reticulum Stress and the Inflammatory Basis of Metabolic Disease
- (2010) Gökhan S. Hotamisligil CELL
- Immunogenic Tumor Cell Death for Optimal Anticancer Therapy: The Calreticulin Exposure Pathway
- (2010) L. Zitvogel et al. CLINICAL CANCER RESEARCH
- EDEM1 accelerates the trimming of 1,2-linked mannose on the C branch of N-glycans
- (2010) N. Hosokawa et al. GLYCOBIOLOGY
- Serine Residues in the Cytosolic Tail of the T-cell Antigen Receptor α-Chain Mediate Ubiquitination and Endoplasmic Reticulum-associated Degradation of the Unassembled Protein
- (2010) Shuhei Ishikura et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Modularity of the Hrd1 ERAD complex underlies its diverse client range
- (2010) Kazue Kanehara et al. JOURNAL OF CELL BIOLOGY
- Route of Antigen Uptake Differentially Impacts Presentation by Dendritic Cells and Activated Monocytes
- (2010) A. O. Kamphorst et al. JOURNAL OF IMMUNOLOGY
- Superior Antitumor Response Induced by Large Stress Protein Chaperoned Protein Antigen Compared with Peptide Antigen
- (2010) X. Y. Wang et al. JOURNAL OF IMMUNOLOGY
- Ubr1 and Ubr2 Function in a Quality Control Pathway for Degradation of Unfolded Cytosolic Proteins
- (2010) Nadinath B. Nillegoda et al. MOLECULAR BIOLOGY OF THE CELL
- Restoration of the immunogenicity of cisplatin-induced cancer cell death by endoplasmic reticulum stress
- (2010) I Martins et al. ONCOGENE
- Ratio of M2 macrophage expression is closely associated with poor prognosis for Angioimmunoblastic T-cell lymphoma (AITL)
- (2010) Daisuke Niino et al. PATHOLOGY INTERNATIONAL
- ER quality control in the biogenesis of MHC class I molecules
- (2010) Daniel C. Chapman et al. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
- UDP-GlC:glycoprotein glucosyltransferase-glucosidase II, the ying-yang of the ER quality control
- (2010) Cecilia D’Alessio et al. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
- Multilayered Mechanism of CD4 Downregulation by HIV-1 Vpu Involving Distinct ER Retention and ERAD Targeting Steps
- (2010) Javier G. Magadán et al. PLoS Pathogens
- ER stress affects processing of MHC class I-associated peptides
- (2009) Diana P Granados et al. BMC IMMUNOLOGY
- Defining the Human Deubiquitinating Enzyme Interaction Landscape
- (2009) Mathew E. Sowa et al. CELL
- The ER-resident ubiquitin-specific protease 19 participates in the UPR and rescues ERAD substrates
- (2009) Gerco C Hassink et al. EMBO REPORTS
- The TRC8 E3 ligase ubiquitinates MHC class I molecules before dislocation from the ER
- (2009) Helen R. Stagg et al. JOURNAL OF CELL BIOLOGY
- Primary Human Tumor Cells Expressing CD155 Impair Tumor Targeting by Down-Regulating DNAM-1 on NK Cells
- (2009) M. Carlsten et al. JOURNAL OF IMMUNOLOGY
- Autophagic Compartments Gain Access to the MHC Class II Compartments in Thymic Epithelium
- (2009) M. Kasai et al. JOURNAL OF IMMUNOLOGY
- EDEM1 Recognition and Delivery of Misfolded Proteins to the SEL1L-Containing ERAD Complex
- (2009) James H. Cormier et al. MOLECULAR CELL
- The Otubain YOD1 Is a Deubiquitinating Enzyme that Associates with p97 to Facilitate Protein Dislocation from the ER
- (2009) Robert Ernst et al. MOLECULAR CELL
- Usa1 Functions as a Scaffold of the HRD-Ubiquitin Ligase
- (2009) Sabine C. Horn et al. MOLECULAR CELL
- The ubiquitin ligase CHIP acts as an upstream regulator of oncogenic pathways
- (2009) Masashi Kajiro et al. NATURE CELL BIOLOGY
- Checkpoints in lymphocyte development and autoimmune disease
- (2009) Harald von Boehmer et al. NATURE IMMUNOLOGY
- Activation of the NLRP3 inflammasome in dendritic cells induces IL-1β–dependent adaptive immunity against tumors
- (2009) François Ghiringhelli et al. NATURE MEDICINE
- Cyclophosphamide and cancer: golden anniversary
- (2009) Ashkan Emadi et al. Nature Reviews Clinical Oncology
- Immunogenic death of colon cancer cells treated with oxaliplatin
- (2009) A Tesniere et al. ONCOGENE
- Herp enhances ER-associated protein degradation by recruiting ubiquilins
- (2008) Tae-Yeon Kim et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- B lymphocytes: how they develop and function
- (2008) T. W. LeBien et al. BLOOD
- Presentation of Telomerase Reverse Transcriptase, a Self-Tumor Antigen, is Down-regulated by Histone Deacetylase Inhibition
- (2008) I. Pellicciotta et al. CANCER RESEARCH
- Ubiquitin Ligase Hul5 Is Required for Fragment-specific Substrate Degradation in Endoplasmic Reticulum-associated Degradation
- (2008) Sonja Kohlmann et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- SEL1L and HRD1 are involved in the degradation of unassembled secretory Ig-µ chains
- (2008) Monica Cattaneo et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Molecular processes that handle — and mishandle — dietary lipids
- (2008) Kevin Jon Williams JOURNAL OF CLINICAL INVESTIGATION
- Expression of galectin-3 in the tumor immune response in colon cancer
- (2008) Patrick Dumont et al. LABORATORY INVESTIGATION
- Gp78 Cooperates with RMA1 in Endoplasmic Reticulum-associated Degradation of CFTRΔF508
- (2008) Daisuke Morito et al. MOLECULAR BIOLOGY OF THE CELL
- ERdj4 and ERdj5 Are Required for Endoplasmic Reticulum-associated Protein Degradation of Misfolded Surfactant Protein C
- (2008) Mei Dong et al. MOLECULAR BIOLOGY OF THE CELL
- OS-9 and GRP94 deliver mutant α1-antitrypsin to the Hrd1–SEL1L ubiquitin ligase complex for ERAD
- (2008) John C. Christianson et al. NATURE CELL BIOLOGY
- Spatial and mechanistic separation of cross-presentation and endogenous antigen presentation
- (2008) Sven Burgdorf et al. NATURE IMMUNOLOGY
- HLA antigen changes in malignant cells: epigenetic mechanisms and biologic significance
- (2008) M Campoli et al. ONCOGENE
- SEL1L nucleates a protein complex required for dislocation of misfolded glycoproteins
- (2008) B. Mueller et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- ERdj5 Is Required as a Disulfide Reductase for Degradation of Misfolded Proteins in the ER
- (2008) R. Ushioda et al. SCIENCE
- CTLA-4 Control over Foxp3+ Regulatory T Cell Function
- (2008) K. Wing et al. SCIENCE
- Endoplasmic Reticulum (ER) Mannosidase I Is Compartmentalized and Required for N-Glycan Trimming to Man5–6GlcNAc2 in Glycoprotein ER-associated Degradation
- (2007) Edward Avezov et al. MOLECULAR BIOLOGY OF THE CELL
Add your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload NowAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started