Endoplasmic Reticulum Degradation-Enhancing α-Mannosidase-like Protein 1 Targets Misfolded HLA-B27 Dimers for Endoplasmic Reticulum-Associated Degradation

Expression of aberrant HLA-B27 molecules is dependent on B27 dosage and peptide supply

(2013) Kirsty McHugh et al.   ANNALS OF THE RHEUMATIC DISEASES

MHC class I molecules are preferentially ubiquitinated on endoplasmic reticulum luminal residues during HRD1 ubiquitin E3 ligase-mediated dislocation

(2013) M. L. Burr et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The MHC Class I Heavy Chain Structurally Conserved Cysteines 101 and 164 Participate in HLA-B27 Dimer Formation

(2011) Izabela Lenart et al.   ANTIOXIDANTS & REDOX SIGNALING

Expression of MHC class I dimers and ERAP1 in an ankylosing spondylitis patient cohort

(2011) Elaine C. Campbell et al.   IMMUNOLOGY

Role of the Endoplasmic Reticulum-associated Degradation (ERAD) Pathway in Degradation of Hepatitis C Virus Envelope Proteins and Production of Virus Particles

(2011) Mohsan Saeed et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

HRD1 and UBE2J1 target misfolded MHC class I heavy chains for endoplasmic reticulum-associated degradation

(2011) Marian L. Burr et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Road to Ruin: Targeting Proteins for Degradation in the Endoplasmic Reticulum

(2011) M. H. Smith et al.   SCIENCE

Mannose Trimming Is Required for Delivery of a Glycoprotein from EDEM1 to XTP3-B and to Late Endoplasmic Reticulum-associated Degradation Steps

(2010) Bella Groisman et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Loss of HRD1-Mediated Protein Degradation Causes Amyloid Precursor Protein Accumulation and Amyloid-  Generation

(2010) M. Kaneko et al.   JOURNAL OF NEUROSCIENCE

An Autophagy-Enhancing Drug Promotes Degradation of Mutant  1-Antitrypsin Z and Reduces Hepatic Fibrosis

(2010) T. Hidvegi et al.   SCIENCE

EDEM1 Recognition and Delivery of Misfolded Proteins to the SEL1L-Containing ERAD Complex

(2009) James H. Cormier et al.   MOLECULAR CELL

Chemical and Biological Approaches Synergize to Ameliorate Protein-Folding Diseases

(2008) Ting-Wei Mu et al.   CELL

The interleukin-23/interleukin-17 axis in spondyloarthritis

(2008) Gerlinde Layh-Schmitt et al.   CURRENT OPINION IN RHEUMATOLOGY

Human HRD1 Promoter Carries a Functional Unfolded Protein Response Element to Which XBP1 but not ATF6 Directly Binds

(2008) K. Yamamoto et al.   JOURNAL OF BIOCHEMISTRY