EDEM2 initiates mammalian glycoprotein ERAD by catalyzing the first mannose trimming step

The role of EDEM2 compared with EDEM1 in ricin transport from the endoplasmic reticulum to the cytosol

(2013) Monika Słomińska-Wojewódzka et al.   BIOCHEMICAL JOURNAL

The Unfolded Protein Response Transducer ATF6 Represents a Novel Transmembrane-type Endoplasmic Reticulum-associated Degradation Substrate Requiring Both Mannose Trimming and SEL1L Protein

(2013) Satoshi Horimoto et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

TALEN-mediated single-base-pair editing identification of an intergenic mutation upstream of BUB1B as causative of PCS (MVA) syndrome

(2013) H. Ochiai et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Repeating pattern of non-RVD variations in DNA-binding modules enhances TALEN activity

(2013) Tetsushi Sakuma et al.   Scientific Reports

Molecular and structural basis for N-glycan-dependent determination of glycoprotein fates in cells

(2012) Yukiko Kamiya et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Cleaning Up: ER-Associated Degradation to the Rescue

(2012) Jeffrey L. Brodsky   CELL

A Shared Endoplasmic Reticulum-associated Degradation Pathway Involving the EDEM1 Protein for Glycosylated and Nonglycosylated Proteins

(2012) Marina Shenkman et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

TALENs: a widely applicable technology for targeted genome editing

(2012) J. Keith Joung et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

A single point mutation in ricin A-chain increases toxin degradation and inhibits EDEM1-dependent ER retrotranslocation

(2011) Iwona Sokołowska et al.   BIOCHEMICAL JOURNAL

SEL1L Is Required for Endoplasmic Reticulum-associated Degradation of Misfolded Luminal Proteins but not Transmembrane Proteins in Chicken DT40 Cell Line

(2011) Satoshi Ninagawa et al.   CELL STRUCTURE AND FUNCTION

In vitro mannose trimming property of human ER α-1,2 mannosidase I

(2011) Jun-ichi Aikawa et al.   GLYCOCONJUGATE JOURNAL

Role of the Endoplasmic Reticulum-associated Degradation (ERAD) Pathway in Degradation of Hepatitis C Virus Envelope Proteins and Production of Virus Particles

(2011) Mohsan Saeed et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Golgi localization of ERManI defines spatial separation of the mammalian glycoprotein quality control system

(2011) Shujuan Pan et al.   MOLECULAR BIOLOGY OF THE CELL

Bypass of glycan-dependent glycoprotein delivery to ERAD by up-regulated EDEM1

(2011) Efrat Ron et al.   MOLECULAR BIOLOGY OF THE CELL

A Complex of Pdi1p and the Mannosidase Htm1p Initiates Clearance of Unfolded Glycoproteins from the Endoplasmic Reticulum

(2011) Robert Gauss et al.   MOLECULAR CELL

Road to Ruin: Targeting Proteins for Degradation in the Endoplasmic Reticulum

(2011) M. H. Smith et al.   SCIENCE

The role of MRH domain-containing lectins in ERAD

(2010) N. Hosokawa et al.   GLYCOBIOLOGY

EDEM1 accelerates the trimming of  1,2-linked mannose on the C branch of N-glycans

(2010) N. Hosokawa et al.   GLYCOBIOLOGY

Sorting things out through endoplasmic reticulum quality control

(2010) Taku Tamura et al.   MOLECULAR MEMBRANE BIOLOGY

ERAD substrate recognition in budding yeast

(2010) Wei Xie et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Htm1 protein generates the N-glycan signal for glycoprotein degradation in the endoplasmic reticulum

(2009) Simone Clerc et al.   JOURNAL OF CELL BIOLOGY

EDEM1 Recognition and Delivery of Misfolded Proteins to the SEL1L-Containing ERAD Complex

(2009) James H. Cormier et al.   MOLECULAR CELL

Defining the Glycan Destruction Signal for Endoplasmic Reticulum-Associated Degradation

(2008) Erin M. Quan et al.   MOLECULAR CELL

Endoplasmic Reticulum (ER) Mannosidase I Is Compartmentalized and Required for N-Glycan Trimming to Man5–6GlcNAc2 in Glycoprotein ER-associated Degradation

(2007) Edward Avezov et al.   MOLECULAR BIOLOGY OF THE CELL