TLR and NLRP3 inflammasome-dependent innate immune responses to tumor-derived autophagosomes (DRibbles)

Autophagy and Inflammasome Interplay

(2015) João D. Martins et al.   DNA AND CELL BIOLOGY

The Translocon Protein Sec61 Mediates Antigen Transport from Endosomes in the Cytosol for Cross-Presentation to CD8+ T Cells

(2015) Matthias Zehner et al.   IMMUNITY

Immunologic manifestations of autophagy

(2015) Vojo Deretic et al.   JOURNAL OF CLINICAL INVESTIGATION

Sec61 in antigen cross-presentation

(2015) Matthias Zehner et al.   Oncotarget

Of LAP, CUPS, and DRibbles – Unconventional Use of Autophagy Proteins for MHC Restricted Antigen Presentation

(2015) Christian Münz   Frontiers in Immunology

Mouse Conventional Dendritic Cells Can be Universally Classified Based on the Mutually Exclusive Expression of XCR1 and SIRPα

(2015) Stephanie Gurka et al.   Frontiers in Immunology

TLR Signals Induce Phagosomal MHC-I Delivery from the Endosomal Recycling Compartment to Allow Cross-Presentation

(2014) Priyanka Nair-Gupta et al.   CELL

Cross-presentation of viral antigens in dribbles leads to efficient activation of virus-specific human memory t cells

(2014) Wei Ye et al.   Journal of Translational Medicine

Pathways of Antigen Processing

(2013) Janice S. Blum et al.   Annual Review of Immunology

K+ Efflux Is the Common Trigger of NLRP3 Inflammasome Activation by Bacterial Toxins and Particulate Matter

(2013) Raúl Muñoz-Planillo et al.   IMMUNITY

The pH Probe CypHer™5E is Effectively Quenched by FM Dyes

(2013) Oliver Welzel et al.   JOURNAL OF FLUORESCENCE

Activation of caspase-1 by the NLRP3 inflammasome regulates the NADPH oxidase NOX2 to control phagosome function

(2013) Anna Sokolovska et al.   NATURE IMMUNOLOGY

iGLuc: a luciferase-based inflammasome and protease activity reporter

(2013) Eva Bartok et al.   NATURE METHODS

Signaling Organelles of the Innate Immune System

(2012) Jonathan C. Kagan   CELL

Activation of autophagy by inflammatory signals limits IL-1β production by targeting ubiquitinated inflammasomes for destruction

(2012) Chong-Shan Shi et al.   NATURE IMMUNOLOGY

Autophagy in the regulation of pathogen replication and adaptive immunity

(2012) Felix Randow et al.   TRENDS IN IMMUNOLOGY

How much of Virus-Specific CD8 T Cell Reactivity is Detected with a Peptide Pool when Compared to Individual Peptides?

(2012) Wenji Zhang et al.   Viruses-Basel

Autophagy-assisted antigen cross-presentation

(2012) Yongxiang Yi et al.   OncoImmunology

Sec22b Regulates Phagosomal Maturation and Antigen Crosspresentation by Dendritic Cells

(2011) Ignacio Cebrian et al.   CELL

Tumor-Derived Autophagosome Vaccine: Mechanism of Cross-Presentation and Therapeutic Efficacy

(2011) Y. Li et al.   CLINICAL CANCER RESEARCH

Tumor-Derived Autophagosome Vaccine: Induction of Cross-Protective Immune Responses against Short-lived Proteins through a p62-Dependent Mechanism

(2011) C. G. Twitty et al.   CLINICAL CANCER RESEARCH

Autophagy Controls IL-1β Secretion by Targeting Pro-IL-1β for Degradation

(2011) James Harris et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Autophagy in immunity and inflammation

(2011) Beth Levine et al.   NATURE

Alpha-alumina nanoparticles induce efficient autophagy-dependent cross-presentation and potent antitumour response

(2011) Haiyan Li et al.   Nature Nanotechnology

The Inflammasomes

(2010) Kate Schroder et al.   CELL

Critical functions of priming and lysosomal damage for NLRP3 activation

(2010) Veit Hornung et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Anti-inflammatory Compounds Parthenolide and Bay 11-7082 Are Direct Inhibitors of the Inflammasome

(2010) Christine Juliana et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cross-presentation of tumor associated antigens through tumor-derived autophagosomes

(2009) Yuhuan Li et al.   Autophagy

Glyburide inhibits the Cryopyrin/Nalp3 inflammasome

(2009) Mohamed Lamkanfi et al.   JOURNAL OF CELL BIOLOGY

A Picky Eater: Exploring the Mechanisms of Selective Autophagy in Human Pathologies

(2008) Aniek van der Vaart et al.   TRAFFIC