MHC Class I Antigen Processing and Presenting Machinery: Organization, Function, and Defects in Tumor Cells

NK cell MHC class I specific receptors (KIR): from biology to clinical intervention

(2012) Ariane Thielens et al.   CURRENT OPINION IN IMMUNOLOGY

Post-Transcriptional and Epigenetic Regulation of Antigen Processing Machinery (APM) Components and HLA-I in Cervical Cancers from Uighur Women

(2012) Ayshamgul Hasim et al.   PLoS One

The endosome–lysosome pathway and information generation in the immune system

(2011) Colin Watts   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Intracellular protein degradation: From a vague idea thru the lysosome and the ubiquitin–proteasome system and onto human diseases and drug targeting

(2011) Aaron Ciechanover   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Expression of antigen processing and presenting molecules in brain metastasis of breast cancer

(2011) Yan Liu et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Association of IFN-  Signal Transduction Defects with Impaired HLA Class I Antigen Processing in Melanoma Cell Lines

(2011) A. Respa et al.   CLINICAL CANCER RESEARCH

Bare lymphocyte syndrome: An opportunity to discover our immune system

(2011) Dilip Shrestha et al.   IMMUNOLOGY LETTERS

Methylation of the promoter of human leukocyte antigen class I in human esophageal squamous cell carcinoma and its histopathological characteristics

(2011) Sun Qifeng et al.   JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY

The carboxypeptidase ACE shapes the MHC class I peptide repertoire

(2011) Xiao Z Shen et al.   NATURE IMMUNOLOGY

Mice completely lacking immunoproteasomes show major changes in antigen presentation

(2011) Eleanor Z Kincaid et al.   NATURE IMMUNOLOGY

Conformation of peptides bound to the transporter associated with antigen processing (TAP)

(2011) M. Herget et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Distinct molecular mechanisms leading to deficient expression of ER-resident aminopeptidases in melanoma

(2010) Esther Kamphausen et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Ontogenesis of rat immune system: Proteasome expression in different cell populations of the developing thymus

(2010) Victoria I. Melnikova et al.   CELLULAR IMMUNOLOGY

Down-regulation of the antigen processing machinery is linked to a loss of inflammatory response in colorectal cancer

(2010) Atsuko Kasajima et al.   HUMAN PATHOLOGY

Identification of E2F1 as an Important Transcription Factor for the Regulation of Tapasin Expression

(2010) Juergen Bukur et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

ABC proteins in antigen translocation and viral inhibition

(2010) David Parcej et al.   Nature Chemical Biology

Antigen processing by nardilysin and thimet oligopeptidase generates cytotoxic T cell epitopes

(2010) Jan H Kessler et al.   NATURE IMMUNOLOGY

Production of an antigenic peptide by insulin-degrading enzyme

(2010) Nicolas Parmentier et al.   NATURE IMMUNOLOGY

HLA class I antigen and transporter associated with antigen processing downregulation in metastatic lesions of head and neck squamous cell carcinoma as a marker of poor prognosis

(2010) Bandoh   ONCOLOGY REPORTS

Downregulation of tapasin expression in primary human oral squamous cell carcinoma: association with clinical outcome

(2010) Qian Jiang et al.   TUMOR BIOLOGY

Downregulation of HLA Class I Molecules in Primary Oral Squamous Cell Carcinomas and Cell Lines

(2009) Qiusha Tang et al.   ARCHIVES OF MEDICAL RESEARCH

Alterations in the antigen processing-presenting machinery of transformed plasma cells are associated with reduced recognition by CD8+ T cells and characterize the progression of MGUS to multiple myeloma

(2009) V. Racanelli et al.   BLOOD

Relationship between HLA class I antigen processing machinery component expression and the clinicopathologic characteristics of bladder carcinomas

(2009) Helen P. Cathro et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Association of HLA class I antigen abnormalities with disease progression and early recurrence in prostate cancer

(2009) Barbara Seliger et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Cancer/testis (CT) antigens: Potential targets for immunotherapy

(2009) Otavia L. Caballero et al.   CANCER SCIENCE

Single nucleotide polymorphisms in antigen processing machinery component ERAP1 significantly associate with clinical outcome in cervical carcinoma

(2009) Akash M. Mehta et al.   GENES CHROMOSOMES & CANCER

Down-regulation of proteasomal subunit MB1 is an independent predictor of improved survival in ovarian cancer

(2009) Ninke Leffers et al.   GYNECOLOGIC ONCOLOGY

MUTYH-associated polyposis carcinomas frequently lose HLA class I expression-a common event amongst DNA-repair-deficient colorectal cancers

(2009) Noel FCC de Miranda et al.   JOURNAL OF PATHOLOGY

In situ analysis of the antigen-processing machinery in acute myeloid leukaemic blasts by tissue microarray

(2009) S Hoves et al.   LEUKEMIA

Down-regulation of HLA class I antigen-processing machinery components in esophageal squamous cell carcinomas: Association with disease progression

(2009) Qiao Liu et al.   SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY

Molecular mechanisms of MHC class I abnormalities and APM components in human tumors

(2008) Barbara Seliger   CANCER IMMUNOLOGY IMMUNOTHERAPY

HLA Class I Antigen Processing Machinery Component Expression and Intratumoral T-Cell Infiltrate as Independent Prognostic Markers in Ovarian Carcinoma

(2008) L. Y. Han et al.   CLINICAL CANCER RESEARCH

Altered expression of endoplasmic reticulum aminopeptidases ERAP1 and ERAP2 in transformed non‐lymphoid human tissues

(2008) Doriana Fruci et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Tumor escape mechanisms: potential role of soluble HLA antigens and NK cells activating ligands

(2008) M. Campoli et al.   TISSUE ANTIGENS