Cross-Presentation of Synthetic Long Peptides by Human Dendritic Cells: A Process Dependent on ERAD Component p97/VCP but Not sec61 and/or Derlin-1

How early studies on secreted and membrane protein quality control gave rise to the ER associated degradation (ERAD) pathway: The early history of ERAD

(2013) Patrick G. Needham et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Dendritic cells process synthetic long peptides better than whole protein, improving antigen presentation and T-cell activation

(2013) Rodney A. Rosalia et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

TLR7 Triggering with Polyuridylic Acid Promotes Cross-Presentation in CD8 + Conventional Dendritic Cells by Enhancing Antigen Preservation and MHC Class I Antigen Permanence on the Dendritic Cell Surface

(2013) M. I. Crespo et al.   JOURNAL OF IMMUNOLOGY

Purification of circulating plasmacytoid dendritic cells using counterflow centrifugal elutriation and immunomagnetic beads

(2012) Delphine Coulais et al.   CYTOTHERAPY

HLA Anchor Optimization of the Melan-A-HLA-A2 Epitope within a Long Peptide Is Required for Efficient Cross-Priming of Human Tumor-Reactive T Cells

(2012) J.-M. Chauvin et al.   JOURNAL OF IMMUNOLOGY

Proteostasis regulation at the endoplasmic reticulum: a new perturbation site for targeted cancer therapy

(2011) Yanfen Liu et al.   CELL RESEARCH

The p97 ATPase associates with EEA1 to regulate the size of early endosomes

(2011) Harish N Ramanathan et al.   CELL RESEARCH

Mannose receptor polyubiquitination regulates endosomal recruitment of p97 and cytosolic antigen translocation for cross-presentation

(2011) M. Zehner et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Modular and Combinatorial View of the Antigen Cross-Presentation Pathway in Dendritic Cells

(2011) Elodie Segura et al.   TRAFFIC

Protein quality control in the ER: balancing the ubiquitin checkbook

(2011) Jasper H.L. Claessen et al.   TRENDS IN CELL BIOLOGY

IFN-α boosts epitope cross-presentation by dendritic cells via modulation of proteasome activity

(2010) Laura Lattanzi et al.   IMMUNOBIOLOGY

Antigen processing by nardilysin and thimet oligopeptidase generates cytotoxic T cell epitopes

(2010) Jan H Kessler et al.   NATURE IMMUNOLOGY

Two abundant proteasome subtypes that uniquely process some antigens presented by HLA class I molecules

(2010) B. Guillaume et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Induction of p53-Specific Immunity by a p53 Synthetic Long Peptide Vaccine in Patients Treated for Metastatic Colorectal Cancer

(2009) F. M. Speetjens et al.   CLINICAL CANCER RESEARCH

Cancer immunotherapy

(2009) Constantin N. Baxevanis et al.   CRITICAL REVIEWS IN CLINICAL LABORATORY SCIENCES

Long-lasting cross-presentation of tumor antigen in human DC

(2009) Florence Faure et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Immunization with a P53 synthetic long peptide vaccine induces P53-specific immune responses in ovarian cancer patients, a phase II trial

(2009) Ninke Leffers et al.   INTERNATIONAL JOURNAL OF CANCER

Vaccination against HPV-16 Oncoproteins for Vulvar Intraepithelial Neoplasia

(2009) Gemma G. Kenter et al.   NEW ENGLAND JOURNAL OF MEDICINE

Antigen storage compartments in mature dendritic cells facilitate prolonged cytotoxic T lymphocyte cross-priming capacity

(2009) N. van Montfoort et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Receptor-mediated phagocytosis elicits cross-presentation in nonprofessional antigen-presenting cells

(2009) A. Giodini et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Induction of Tumor-Specific CD4+ and CD8+ T-Cell Immunity in Cervical Cancer Patients by a Human Papillomavirus Type 16 E6 and E7 Long Peptides Vaccine

(2008) M. J.P. Welters et al.   CLINICAL CANCER RESEARCH

Endocytosis mechanisms and the cell biology of antigen presentation

(2008) Sven Burgdorf et al.   CURRENT OPINION IN IMMUNOLOGY

Superior induction of anti-tumor CTL immunity by extended peptide vaccines involves prolonged, DC-focused antigen presentation

(2008) Martijn S. Bijker et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Cancer Immunotherapy by Dendritic Cells

(2008) Cornelis J.M. Melief   IMMUNITY

Spatial and mechanistic separation of cross-presentation and endogenous antigen presentation

(2008) Sven Burgdorf et al.   NATURE IMMUNOLOGY