Deacetylation of HSPA5 by HDAC6 leads to GP78-mediated HSPA5 ubiquitination at K447 and suppresses metastasis of breast cancer

CYP3A isoforms in Ewing's sarcoma tumours: an immunohistochemical study with clinical correlation

(2015) Hamid Zia et al.   INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY

Proteomic Study of Microsomal Proteins Reveals a Key Role forArabidopsisAnnexin 1 in Mediating Heat Stress-Induced Increase in Intracellular Calcium Levels

(2015) Xu Wang et al.   MOLECULAR & CELLULAR PROTEOMICS

Gp78, an E3 Ubiquitin Ligase Acts as a Gatekeeper Suppressing Nonalcoholic Steatohepatitis (NASH) and Liver Cancer

(2015) Tianpeng Zhang et al.   PLoS One

De-acetylation and degradation of HSPA5 is critical for E1A metastasis suppression in breast cancer cells

(2015) Yi-Wen Chang et al.   Oncotarget

CYP3A4 Expression in Breast Cancer and its Association with Risk Factors in Mexican Women

(2014) Esau Floriano-Sanchez et al.   Asian Pacific Journal of Cancer Prevention

Prospective associations between serum biomarkers of lipid metabolism and overall, breast and prostate cancer risk

(2014) Mathilde His et al.   EUROPEAN JOURNAL OF EPIDEMIOLOGY

Simvastatin, an HMG-CoA reductase inhibitor, exhibits anti-metastatic and anti-tumorigenic effects in endometrial cancer

(2014) Monica N. Schointuch et al.   GYNECOLOGIC ONCOLOGY

Human Liver Cytochrome P450 3A4 Ubiquitination

(2014) YongQiang Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The ubiquitin–proteasome-system

(2013) Thomas Sommer et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

The ubiquitin proteasome system — Implications for cell cycle control and the targeted treatment of cancer

(2013) Florian Bassermann et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Function of BRCA1 in the DNA Damage Response Is Mediated by ADP-Ribosylation

(2013) Mo Li et al.   CANCER CELL

Siah: A Promising Anticancer Target

(2013) C. S. F. Wong et al.   CANCER RESEARCH

Evaluation of ubiquitinated proteins by proteomics reveals the role of the ubiquitin proteasome system in the regulation of Grp75 and Grp78 chaperone proteins during intestinal inflammation

(2013) Julien Bertrand et al.   PROTEOMICS

The Skp2-SCF E3 Ligase Regulates Akt Ubiquitination, Glycolysis, Herceptin Sensitivity, and Tumorigenesis

(2012) Chia-Hsin Chan et al.   CELL

A Critical Role for GRP78/BiP in the Tumor Microenvironment for Neovascularization during Tumor Growth and Metastasis

(2011) D. Dong et al.   CANCER RESEARCH

Clinical significance of steroid and xenobiotic receptor and its targeted gene CYP3A4 in human prostate cancer

(2011) Tetsuya Fujimura et al.   CANCER SCIENCE

A Genomic Predictor of Response and Survival Following Taxane-Anthracycline Chemotherapy for Invasive Breast Cancer

(2011) Christos Hatzis   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Integrative analysis of the ubiquitin proteome isolated using Tandem Ubiquitin Binding Entities (TUBEs)

(2011) Fernando Lopitz-Otsoa et al.   Journal of Proteomics

CYP3A4 expression to predict treatment response to docetaxel for metastasis and recurrence of primary breast cancer

(2011) Kenichi Sakurai et al.   SURGERY TODAY

Glucose-Regulated Protein 78 (GRP78) Silencing Enhances Cell Migration but Does Not Influence Cell Proliferation in Hepatocellular Carcinoma

(2010) Yu-Jia Chang et al.   ANNALS OF SURGICAL ONCOLOGY

Downregulation of MicroRNA miR-520h by E1A Contributes to Anticancer Activity

(2010) Jen-Liang Su et al.   CANCER RESEARCH

Control of cholesterol synthesis through regulated ER-associated degradation of HMG CoA reductase

(2010) Youngah Jo et al.   CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY

A Role for KAI1 in Promotion of Cell Proliferation and Mammary Gland Hyperplasia by the gp78 Ubiquitin Ligase

(2010) Bharat Joshi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Treatment with Panobinostat Induces Glucose-Regulated Protein 78 Acetylation and Endoplasmic Reticulum Stress in Breast Cancer Cells

(2010) Rekha Rao et al.   MOLECULAR CANCER THERAPEUTICS

Ubiquitin-like protein conjugation and the ubiquitin–proteasome system as drug targets

(2010) Lynn Bedford et al.   NATURE REVIEWS DRUG DISCOVERY

RING Domain E3 Ubiquitin Ligases

(2009) Raymond J. Deshaies et al.   Annual Review of Biochemistry

Gp78, an ER associated E3, promotes SOD1 and ataxin-3 degradation

(2009) Zheng Ying et al.   HUMAN MOLECULAR GENETICS

Identification of Residues on Hsp70 and Hsp90 Ubiquitinated by the Cochaperone CHIP

(2009) Lenka Kundrat et al.   JOURNAL OF MOLECULAR BIOLOGY

The complex biology of autocrine motility factor/phosphoglucose isomerase (AMF/PGI) and its receptor, the gp78/AMFR E3 ubiquitin ligase

(2009) Maria Fairbank et al.   Molecular BioSystems

HDAC6 inhibition enhances 17-AAG-mediated abrogation of hsp90 chaperone function in human leukemia cells

(2008) R. Rao et al.   BLOOD

Role of Acetylation and Extracellular Location of Heat Shock Protein 90  in Tumor Cell Invasion

(2008) Y. Yang et al.   CANCER RESEARCH

Critical Role of the Stress Chaperone GRP78/BiP in Tumor Proliferation, Survival, and Tumor Angiogenesis in Transgene-Induced Mammary Tumor Development

(2008) D. Dong et al.   CANCER RESEARCH

Glucose-regulated protein 78 regulates multiple malignant phenotypes in head and neck cancer and may serve as a molecular target of therapeutic intervention

(2008) C.-C. Chiu et al.   MOLECULAR CANCER THERAPEUTICS