The ER membrane-anchored ubiquitin ligase Hrd1 is a positive regulator of T-cell immunity

T Cell Antigen Receptor Recognition of Antigen-Presenting Molecules

(2015) Jamie Rossjohn et al.   Annual Review of Immunology

Hrd1 suppresses Nrf2-mediated cellular protection during liver cirrhosis

(2014) T. Wu et al.   GENES & DEVELOPMENT

Hrd1-mediated BLIMP-1 ubiquitination promotes dendritic cell MHCII expression for CD4 T cell priming during inflammation

(2014) Heeyoung Yang et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Toll-like receptor-mediated IRE1α activation as a therapeutic target for inflammatory arthritis

(2013) Quan Qiu et al.   EMBO JOURNAL

The Serine-threonine Kinase Inositol-requiring Enzyme 1α (IRE1α) Promotes IL-4 Production in T Helper Cells

(2013) Kyeorda L. Kemp et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Tle4 Regulates Epigenetic Silencing of Gamma Interferon Expression during Effector T Helper Cell Tolerance

(2013) S. Bandyopadhyay et al.   MOLECULAR AND CELLULAR BIOLOGY

MHC class I molecules are preferentially ubiquitinated on endoplasmic reticulum luminal residues during HRD1 ubiquitin E3 ligase-mediated dislocation

(2013) M. L. Burr et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IRE1α activation protects mice against acetaminophen-induced hepatotoxicity

(2012) Kyu Yeon Hur et al.   JOURNAL OF EXPERIMENTAL MEDICINE

IL-26 Is Overexpressed in Rheumatoid Arthritis and Induces Proinflammatory Cytokine Production and Th17 Cell Generation

(2012) Murielle Corvaisier et al.   PLOS BIOLOGY

Heat-shock protein gp96/grp94 is an essential chaperone for the platelet glycoprotein Ib-IX-V complex

(2011) M. Staron et al.   BLOOD

ICOS Receptor Instructs T Follicular Helper Cell versus Effector Cell Differentiation via Induction of the Transcriptional Repressor Bcl6

(2011) Youn Soo Choi et al.   IMMUNITY

Differentiation of Effector CD4 T Cell Populations

(2010) Jinfang Zhu et al.   Annual Review of Immunology

Role of Interleukin 17 in Arthritis Chronicity through Survival of Synoviocytes via Regulation of Synoviolin Expression

(2010) Myew-Ling Toh et al.   PLoS One

T Cell Activation

(2009) Jennifer E. Smith-Garvin et al.   Annual Review of Immunology

The type III histone deacetylase Sirt1 is essential for maintenance of T cell tolerance in mice

(2009) Jinping Zhang et al.   JOURNAL OF CLINICAL INVESTIGATION

Decreased FoxP3 gene expression in the nasal secretions from patients with allergic rhinitis

(2009) Sang-Myeong Lee et al.   OTOLARYNGOLOGY-HEAD AND NECK SURGERY

FoxP3 maintains Treg unresponsiveness by selectively inhibiting the promoter DNA-binding activity of AP-1

(2008) S.-M. Lee et al.   BLOOD

Synoviolin promotes IRE1 ubiquitination and degradation in synovial fibroblasts from mice with collagen-induced arthritis

(2008) Beixue Gao et al.   EMBO REPORTS