Advanced Biomaterials and Processing Methods for Liver Regeneration: State‐of‐the‐Art and Future Trends

A cell lines derived microfluidic liver model for investigation of hepatotoxicity induced by drug-drug interaction

(2019) Jiu Deng et al.   Biomicrofluidics

Organoids of liver diseases: From bench to bedside

(2019) Li-Jun Wu et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Liver organoids: from basic research to therapeutic applications

(2019) Nicole Prior et al.   GUT

Generation of expandable human pluripotent stem cell-derived hepatocyte-like liver organoids

(2019) Seon Ju Mun et al.   JOURNAL OF HEPATOLOGY

A microfluidic 3D hepatocyte chip for hepatotoxicity testing of nanoparticles

(2019) Lei Li et al.   Nanomedicine

Generation of fully functional hepatocyte-like organoids from human induced pluripotent stem cells mixed with Endothelial Cells

(2019) Giuseppe Pettinato et al.   Scientific Reports

3D-printed gelatin scaffolds of differing pore geometry modulate hepatocyte function and gene expression

(2018) Phillip L. Lewis et al.   Acta Biomaterialia

Efficient and cost-effective generation of hepatocyte-like cells through microparticle-mediated delivery of growth factors in a 3D culture of human pluripotent stem cells

(2018) Zeinab Heidariyan et al.   BIOMATERIALS

Generation of matched patient-derived xenograft in vitro-in vivo models using 3D macroporous hydrogels for the study of liver cancer

(2018) Eliza Li Shan Fong et al.   BIOMATERIALS

A decade of progress in liver regenerative medicine

(2018) Jingwei Zhang et al.   BIOMATERIALS

Modeling human diseases with induced pluripotent stem cells: from 2D to 3D and beyond

(2018) Chun Liu et al.   DEVELOPMENT

Organ/body-on-a-chip based on microfluidic technology for drug discovery

(2018) Hiroshi Kimura et al.   Drug Metabolism and Pharmacokinetics

Novel decellularized liver matrix-alginate hybrid gel beads for the 3D culture of hepatocellular carcinoma cells

(2018) Dongsheng Sun et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Halfway between 2D and Animal Models: Are 3D Cultures the Ideal Tool to Study Cancer-Microenvironment Interactions?

(2018) Jessica Hoarau-Véchot et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Recent advances in microfluidic technologies for cell-to-cell interaction studies

(2018) Mario Rothbauer et al.   LAB ON A CHIP

Three-Dimensional Bioprinting of Hepatic Structures with Directly Converted Hepatocyte-Like Cells

(2018) Kyojin Kang et al.   TISSUE ENGINEERING PART A

Prolongation of liver-specific function for primary hepatocytes maintenance in 3D printed architectures

(2018) Yohan Kim et al.   Organogenesis

Microfluidic Devices for Drug Delivery Systems and Drug Screening

(2018) Samar Damiati et al.   Genes

Human iPS derived progenitors bioengineered into liver organoids using an inverted colloidal crystal poly (ethylene glycol) scaffold

(2018) Soon Seng Ng et al.   BIOMATERIALS

Rapid 3D bioprinting of decellularized extracellular matrix with regionally varied mechanical properties and biomimetic microarchitecture

(2018) Xuanyi Ma et al.   BIOMATERIALS

Development of a biomimetic liver tumor-on-a-chip model based on decellularized liver matrix for toxicity testing

(2018) Siming Lu et al.   LAB ON A CHIP

Long-Term Expansion of Functional Mouse and Human Hepatocytes as 3D Organoids

(2018) Huili Hu et al.   CELL

Generation of Multilayered 3D Structures of HepG2 Cells Using a Bio-printing Technique

(2017) Hyeryeon Jeon et al.   Gut and Liver

Evaluation of biofouling in stainless microfluidic channels for implantable multilayered dialysis device

(2017) Takashi Ota et al.   JAPANESE JOURNAL OF APPLIED PHYSICS

Preparation and characterization of a chitosan/galactosylated hyaluronic acid/heparin scaffold for hepatic tissue engineering

(2017) Jinyong Fan et al.   JOURNAL OF BIOMATERIALS SCIENCE-POLYMER EDITION

Long-term liver-specific functions of hepatocytes in electrospun chitosan nanofiber scaffolds coated with fibronectin

(2017) Divya Rajendran et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

Recent Progress in Hepatocyte Culture Models and Their Application to the Assessment of Drug Metabolism, Transport, and Toxicity in Drug Discovery: The Value of Tissue Engineering for the Successful Development of a Microphysiological System

(2017) Kazuhiro Tetsuka et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

In vivo construction of liver tissue by implantation of a hepatic non-parenchymal/adipose-derived stem cell sheet

(2017) Mio Fujii et al.   Journal of Tissue Engineering and Regenerative Medicine

Printing cures: Organovo advances with 3D-printed liver tissue

(2017) Ellen P. Neff   LAB ANIMAL

Human primary liver cancer–derived organoid cultures for disease modeling and drug screening

(2017) Laura Broutier et al.   NATURE MEDICINE

Mechanical forces direct stem cell behaviour in development and regeneration

(2017) Kyle H. Vining et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

In situ expansion of engineered human liver tissue in a mouse model of chronic liver disease

(2017) Kelly R. Stevens et al.   Science Translational Medicine

3D Printing in Liver Surgery: A Systematic Review

(2017) Jan Sylwester Witowski et al.   Telemedicine and e-Health

Heparin/Collagen 3D Scaffold Accelerates Hepatocyte Differentiation of Wharton’s Jelly-Derived Mesenchymal Stem Cells

(2017) Fatemeh Aleahmad et al.   Tissue Engineering and Regenerative Medicine

A Drug-Induced Hybrid Electrospun Poly-Capro-Lactone: Cell-Derived Extracellular Matrix Scaffold for Liver Tissue Engineering

(2017) Rhiannon Grant et al.   TISSUE ENGINEERING PART A

A clinical-scale BioArtificial Liver, developed for GMP, improved clinical parameters of liver function in porcine liver failure

(2017) Clare Selden et al.   Scientific Reports

Autologous bone marrow-derived cell transplantation in decompensated alcoholic liver disease: what is the impact on liver histology and gene expression patterns?

(2017) Nicolas Lanthier et al.   Stem Cell Research & Therapy

3D Cell Printed Tissue Analogues: A New Platform for Theranostics

(2017) Yeong-Jin Choi et al.   Theranostics

Recent Progress in Developing Injectable Matrices for Enhancing Cell Delivery and Tissue Regeneration

(2017) Xinming Tong et al.   Advanced Healthcare Materials

3D Printing in Liver Surgery: A Systematic Review

(2017) Jan Sylwester Witowski et al.   Telemedicine and e-Health

Heparin/Collagen 3D Scaffold Accelerates Hepatocyte Differentiation of Wharton’s Jelly-Derived Mesenchymal Stem Cells

(2017) Fatemeh Aleahmad et al.   Tissue Engineering and Regenerative Medicine

Bioelectronic measurement and feedback control of molecules in living cells

(2017) Areen Banerjee et al.   Scientific Reports

A perfusion incubator liver chip for 3D cell culture with application on chronic hepatotoxicity testing

(2017) Fang Yu et al.   Scientific Reports

High-throughput screening approaches and combinatorial development of biomaterials using microfluidics

(2016) David Barata et al.   Acta Biomaterialia

3D Bioprinting for Tissue and Organ Fabrication

(2016) Yu Shrike Zhang et al.   ANNALS OF BIOMEDICAL ENGINEERING

Gene network activity in cultivated primary hepatocytes is highly similar to diseased mammalian liver tissue

(2016) Patricio Godoy et al.   ARCHIVES OF TOXICOLOGY

Bio-inspired in situ crosslinking and mineralization of electrospun collagen scaffolds for bone tissue engineering

(2016) Chetna Dhand et al.   BIOMATERIALS

Screening applications in drug discovery based on microfluidic technology

(2016) P. Eribol et al.   Biomicrofluidics

3D bioprinting for engineering complex tissues

(2016) Christian Mandrycky et al.   BIOTECHNOLOGY ADVANCES

A versatile modular bioreactor platform for Tissue Engineering

(2016) Sebastian Schuerlein et al.   Biotechnology Journal

Improved survival of porcine acute liver failure by a bioartificial liver device implanted with induced human functional hepatocytes

(2016) Xiao-Lei Shi et al.   CELL RESEARCH

Efficacy of Multilayered Hepatocyte Sheet Transplantation for Radiation-Induced Liver Damage and Partial Hepatectomy in a Rat Model

(2016) Zhassulan Baimakhanov et al.   CELL TRANSPLANTATION

Stem cell-derived cell-sheets for connective tissue engineering

(2016) Puay Yong Neo et al.   CONNECTIVE TISSUE RESEARCH

Human hepatocytes loaded in 3D bioprinting generate mini-liver

(2016) Cheng Zhong et al.   Hepatobiliary & Pancreatic Diseases International

Evaluation of PCL/chitosan electrospun nanofibers for liver tissue engineering

(2016) Dariush Semnani et al.   International Journal of Polymeric Materials and Polymeric Biomaterials

Self-assembling peptide nanofiber hydrogels in tissue engineering and regenerative medicine: Progress, design guidelines, and applications

(2016) Sotirios Koutsopoulos   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

Improved human endometrial stem cells differentiation into functional hepatocyte-like cells on a glycosaminoglycan/collagen-grafted polyethersulfone nanofibrous scaffold

(2016) Farzaneh Khademi et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS

Transplantation of a human iPSC-derived hepatocyte sheet increases survival in mice with acute liver failure

(2016) Yasuhito Nagamoto et al.   JOURNAL OF HEPATOLOGY

Implantable Microfluidic Device with Hydrogel Permeable Membrane for Delivering Chemical Compounds and Imaging Neural Cells in Living Mice

(2016) Hiroaki Takehara et al.   JOURNAL OF PHOTOPOLYMER SCIENCE AND TECHNOLOGY

Three-dimensional polymer scaffolds for enhanced differentiation of human mesenchymal stem cells to hepatocyte-like cells: a comparative study

(2016) Swati Chitrangi et al.   Journal of Tissue Engineering and Regenerative Medicine

Engineering a perfusable 3D human liver platform from iPS cells

(2016) Arnout Schepers et al.   LAB ON A CHIP

Controlled assembly of heterotypic cells in a core–shell scaffold: organ in a droplet

(2016) Qiushui Chen et al.   LAB ON A CHIP

The upcoming 3D-printing revolution in microfluidics

(2016) Nirveek Bhattacharjee et al.   LAB ON A CHIP

Biodegradable scaffold with built-in vasculature for organ-on-a-chip engineering and direct surgical anastomosis

(2016) Boyang Zhang et al.   NATURE MATERIALS

Culture and establishment of self-renewing human and mouse adult liver and pancreas 3D organoids and their genetic manipulation

(2016) Laura Broutier et al.   Nature Protocols

Deterministically patterned biomimetic human iPSC-derived hepatic model via rapid 3D bioprinting

(2016) Xuanyi Ma et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Arbitrarily Accessible 3D Microfluidic Device for Combinatorial High-Throughput Drug Screening

(2016) Zhuofa Chen et al.   SENSORS

Microfluidic cell chips for high-throughput drug screening

(2016) Chun-Wei Chi et al.   Bioanalysis

Enhanced cryopreservation of MSCs in microfluidic bioreactor by regulated shear flow

(2016) Akalabya Bissoyi et al.   Scientific Reports

A Patient-Inspired Ex Vivo Liver Tissue Engineering Approach with Autologous Mesenchymal Stem Cells and Hepatogenic Serum

(2016) Dillip K. Bishi et al.   Advanced Healthcare Materials

Biomaterials and Culture Technologies for Regenerative Therapy of Liver Tissue

(2016) Roman A. Perez et al.   Advanced Healthcare Materials

3D Bioprinting for Organ Regeneration

(2016) Haitao Cui et al.   Advanced Healthcare Materials

Open-Porous Hydroxyapatite Scaffolds for Three-Dimensional Culture of Human Adult Liver Cells

(2016) Anthony Finoli et al.   Biomed Research International

A versatile modular bioreactor platform for Tissue Engineering

(2016) Sebastian Schuerlein et al.   Biotechnology Journal

Evaluation of PCL/chitosan electrospun nanofibers for liver tissue engineering

(2016) Dariush Semnani et al.   International Journal of Polymeric Materials and Polymeric Biomaterials

3D printed structures for delivery of biomolecules and cells: tissue repair and regeneration

(2016) Ju Young Park et al.   Journal of Materials Chemistry B

Modulating the Substrate Stiffness to Manipulate Differentiation of Resident Liver Stem Cells and to Improve the Differentiation State of Hepatocytes

(2016) Angela Maria Cozzolino et al.   Stem Cells International

Elastin in the Liver

(2016) Jiří Kanta   Frontiers in Physiology

A heparin-modified thermoresponsive surface with heparin-binding epidermal growth factor-like growth factor for maintaining hepatic functions in vitro and harvesting hepatocyte sheets

(2016) Yoshinori Arisaka et al.   Regenerative Therapy

Investigating Nonalcoholic Fatty Liver Disease in a Liver-on-a-Chip Microfluidic Device

(2016) Manuele Gori et al.   PLoS One

Bioprinted 3D Primary Liver Tissues Allow Assessment of Organ-Level Response to Clinical Drug Induced Toxicity In Vitro

(2016) Deborah G. Nguyen et al.   PLoS One

Stiffening hydrogels for investigating the dynamics of hepatic stellate cell mechanotransduction during myofibroblast activation

(2016) Steven R. Caliari et al.   Scientific Reports

The alterations in the extracellular matrix composition guide the repair of damaged liver tissue

(2016) Mariliis Klaas et al.   Scientific Reports

Isolation and co-culture of rat parenchymal and non-parenchymal liver cells to evaluate cellular interactions and response

(2016) Shyam Sundhar Bale et al.   Scientific Reports

Combined Effect of Cryogel Matrix and Temperature-Reversible Soluble–Insoluble Polymer for the Development of in Vitro Human Liver Tissue

(2015) Jyoti Kumari et al.   ACS Applied Materials & Interfaces

Decellularization and Recellularization of Rat Livers With Hepatocytes and Endothelial Progenitor Cells

(2015) Pengcheng Zhou et al.   ARTIFICIAL ORGANS

Vascularized subcutaneous human liver tissue from engineered hepatocyte/fibroblast sheets in mice

(2015) Yusuke Sakai et al.   BIOMATERIALS

Polysaccharide-based strategies for heart tissue engineering

(2015) Amanda K.A. Silva et al.   CARBOHYDRATE POLYMERS

Phases I-II Matched Case-Control Study of Human Fetal Liver Cell Transplantation for Treatment of Chronic Liver Disease

(2015) Giada Pietrosi et al.   CELL TRANSPLANTATION

Enhanced Antioxidant Capacity of Dental Pulp-Derived iPSC-Differentiated Hepatocytes and Liver Regeneration by Injectable HGF-Releasing Hydrogel in Fulminant Hepatic Failure

(2015) Chih-Hung Chiang et al.   CELL TRANSPLANTATION

Fabrication of macroporous cryogels as potential hepatocyte carriers for bioartificial liver support

(2015) Era Jain et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

Fish collagen-based scaffold containing PLGA microspheres for controlled growth factor delivery in skin tissue engineering

(2015) Huan Cao et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

Advances in microfluidic platforms for analyzing and regulating human pluripotent stem cells

(2015) Tongcheng Qian et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Challenges to Liver Transplantation and Strategies to Improve Outcomes

(2015) Philipp Dutkowski et al.   GASTROENTEROLOGY

Liver regeneration using decellularized splenic scaffold: a novel approach in tissue engineering

(2015) Jun-Xi Xiang et al.   Hepatobiliary & Pancreatic Diseases International

Using reconfigurable microfluidics to study the role of HGF in autocrine and paracrine signaling of hepatocytes

(2015) Dipali Patel et al.   Integrative Biology

Alginate composites for bone tissue engineering: A review

(2015) Jayachandran Venkatesan et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Degradable hydrogels derived from PEG-diacrylamide for hepatic tissue engineering

(2015) Kelly R. Stevens et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

Hepatic regenerative medicine

(2015) Giuseppe Mazza et al.   JOURNAL OF HEPATOLOGY

Influence of 3D porous galactose containing PVA/gelatin hydrogel scaffolds on three-dimensional spheroidal morphology of hepatocytes

(2015) Kirthanashri S. Vasanthan et al.   JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE

Fabrication of functional 3D hepatic tissues with polarized hepatocytes by stacking endothelial cell sheets in vitro

(2015) Kyungsook Kim et al.   Journal of Tissue Engineering and Regenerative Medicine

A building-block approach to 3D printing a multichannel, organ-regenerative scaffold

(2015) Xiaohong Wang et al.   Journal of Tissue Engineering and Regenerative Medicine

Liver injury-on-a-chip: microfluidic co-cultures with integrated biosensors for monitoring liver cell signaling during injury

(2015) Qing Zhou et al.   LAB ON A CHIP

3D liver models on a microplatform: well-defined culture, engineering of liver tissue and liver-on-a-chip

(2015) Da Yoon No et al.   LAB ON A CHIP

Clinical human hepatocyte transplantation: Current status and challenges

(2015) Anil Dhawan   LIVER TRANSPLANTATION

Preparation of a sponge-like biocomposite agarose–chitosan scaffold with primary hepatocytes for establishing an in vitro 3D liver tissue model

(2015) Anuj Tripathi et al.   RSC Advances

Human mesenchymal stem cell-engineered hepatic cell sheets accelerate liver regeneration in mice

(2015) Noriko Itaba et al.   Scientific Reports

High-Throughput Microfluidic Platform for 3D Cultures of Mesenchymal Stem Cells, Towards Engineering Developmental Processes

(2015) Paola Occhetta et al.   Scientific Reports

The impact of repeated autologous infusion of haematopoietic stem cells in patients with liver insufficiency

(2015) Abdel-Rahman N. Zekri et al.   Stem Cell Research & Therapy

Transplantation of hESC-derived hepatocytes protects mice from liver injury

(2015) Laia Tolosa et al.   Stem Cell Research & Therapy

Bifunctional Polysulfone-Chitosan Composite Hollow Fiber Membrane for Bioartificial Liver

(2015) Rohit S. Teotia et al.   ACS Biomaterials-Science & Engineering

Bifunctional Polysulfone-Chitosan Composite Hollow Fiber Membrane for Bioartificial Liver

(2015) Rohit S. Teotia et al.   ACS Biomaterials Science & Engineering

Polypeptide Thermogels as a Three Dimensional Culture Scaffold for Hepatogenic Differentiation of Human Tonsil-Derived Mesenchymal Stem Cells

(2014) Seung-Jin Kim et al.   ACS Applied Materials & Interfaces

Bioreactor technologies to support liver function in vitro

(2014) Mohammad R. Ebrahimkhani et al.   ADVANCED DRUG DELIVERY REVIEWS

Hepatocyte Cocultures with Endothelial Cells and Fibroblasts on Micropatterned Fibrous Mats to Promote Liver-Specific Functions and Capillary Formation Capabilities

(2014) Yaowen Liu et al.   BIOMACROMOLECULES

Immune-protected xenogeneic bioartificial livers with liver-specific microarchitecture and hydrogel-encapsulated cells

(2014) Da Yoon No et al.   BIOMATERIALS

Effects of angiogenic factors and 3D-microenvironments on vascularization within sandwich cultures

(2014) Akihiro Nishiguchi et al.   BIOMATERIALS

Differentiation of liver progenitor cell line to functional organotypic cultures in 3D nanofibrillar cellulose and hyaluronan-gelatin hydrogels

(2014) Melina M. Malinen et al.   BIOMATERIALS

Cell sheet engineering for regenerative medicine: Current challenges and strategies

(2014) Toshiyuki Owaki et al.   Biotechnology Journal

Enhanced liver functions of HepG2 cells in the alginate/xyloglucan scaffold

(2014) Xiaojie Deng et al.   BIOTECHNOLOGY LETTERS

Preparation and characterization of galactosylated alginate–chitosan oligomer microcapsule for hepatocytes microencapsulation

(2014) Meng Tian et al.   CARBOHYDRATE POLYMERS

Molecular Interactions Driving the Layer-by-Layer Assembly of Multilayers

(2014) João Borges et al.   CHEMICAL REVIEWS

Polyelectrolyte multilayered assemblies in biomedical technologies

(2014) Rui R. Costa et al.   CHEMICAL SOCIETY REVIEWS

Cell culture in autologous fibrin scaffolds for applications in tissue engineering

(2014) Pilar de la Puente et al.   EXPERIMENTAL CELL RESEARCH

Silk sericin–alginate–chitosan microcapsules: Hepatocytes encapsulation for enhanced cellular functions

(2014) Sunita Nayak et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Electrospun gelatin/PCL and collagen/PLCL scaffolds for vascular tissue engineering

(2014) Wei Fu et al.   International Journal of Nanomedicine

The Shape of Things to Come

(2014) Mark H. Michalski et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Advances in 3D cell culture technologies enabling tissue-like structures to be createdin vitro

(2014) Eleanor Knight et al.   JOURNAL OF ANATOMY

Construction of three-dimensional liver tissue models by cell accumulation technique and maintaining their metabolic functions for long-term culture without medium change

(2014) Atsushi Matsuzawa et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

Local Delivery of Vascular Endothelial Growth Factor via Nanofiber Matrix Improves Liver Regeneration After Extensive Hepatectomy in Rats

(2014) Yuan-Quan Yu et al.   Journal of Biomedical Nanotechnology

A microfluidic-based platform for tumour spheroid culture, monitoring and drug screening

(2014) K. Kwapiszewska et al.   LAB ON A CHIP

Galactosylated poly(ε-caprolactone) membrane promoted liver-specific functions of HepG2 cells in vitro

(2014) Yan Zhang et al.   Materials Science & Engineering C-Materials for Biological Applications

3D bioprinting of tissues and organs

(2014) Sean V Murphy et al.   NATURE BIOTECHNOLOGY

An implantable microfluidic device for self-monitoring of intraocular pressure

(2014) Ismail E Araci et al.   NATURE MEDICINE

Mechanotransduction and extracellular matrix homeostasis

(2014) Jay D. Humphrey et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Physical influences of the extracellular environment on cell migration

(2014) Guillaume Charras et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Three-dimensional organotypic culture: experimental models of mammalian biology and disease

(2014) Eliah R. Shamir et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Remodelling the extracellular matrix in development and disease

(2014) Caroline Bonnans et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Alginate Microencapsulated Hepatocytes Optimised for Transplantation in Acute Liver Failure

(2014) Suttiruk Jitraruch et al.   PLoS One

Cellularized Biosynthetic Microhydrogel Polymers for Intravascular Liver Tissue Regeneration Therapy

(2014) Tarek Saadi et al.   TISSUE ENGINEERING PART A

Cellular Mechanisms of Tissue Fibrosis. 5. Novel insights into liver fibrosis

(2013) Ariane Mallat et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

A multicellular 3D heterospheroid model of liver tumor and stromal cells in collagen gel for anti-cancer drug testing

(2013) Derek Yip et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Study of porcine hepatocyte-entrapped bioartificial liver in surgery-induced fulminant hepatic failure rabbits

(2013) Chi-Chang Lin et al.   BIOCHEMICAL ENGINEERING JOURNAL

Self-Supported Fibrin-Polyvinyl Alcohol Interpenetrating Polymer Networks: An Easily Handled and Rehydratable Biomaterial

(2013) Laurent Bidault et al.   BIOMACROMOLECULES

Liver Extracellular Matrix Providing Dual Functions of Two-Dimensional Substrate Coating and Three-Dimensional Injectable Hydrogel Platform for Liver Tissue Engineering

(2013) Jung Seung Lee et al.   BIOMACROMOLECULES

Hepatogenesis of murine induced pluripotent stem cells in 3D micro-cavitary hydrogel system for liver regeneration

(2013) Ting Ting Lau et al.   BIOMATERIALS

Corrigendum: Silk fibroin based biomimetic artificial extracellular matrix for hepatic tissue engineering applications

(2013) Naresh Kasoju et al.   Biomedical Materials

Cells and Materials for Liver Tissue Engineering

(2013) Yuan-Sheng Li et al.   CELL TRANSPLANTATION

Fabrication and characterization of microfluidic liver-on-a-chip using microsomal enzymes

(2013) Jungwoo Lee et al.   ENZYME AND MICROBIAL TECHNOLOGY

Chitosan-based biomaterials for tissue engineering

(2013) Florence Croisier et al.   EUROPEAN POLYMER JOURNAL

Biomaterials for liver tissue engineering

(2013) Era Jain et al.   Hepatology International

Fabrication of poly (ϵ-caprolactone) microfiber scaffolds with varying topography and mechanical properties for stem cell-based tissue engineering applications

(2013) Junghyuk Ko et al.   JOURNAL OF BIOMATERIALS SCIENCE-POLYMER EDITION

Solubilized matrix derived from decellularized liver as a growth factor-immobilizable scaffold for hepatocyte culture

(2013) Shintaro Nakamura et al.   JOURNAL OF BIOSCIENCE AND BIOENGINEERING

Hybrid sponge comprised of galactosylated chitosan and hyaluronic acid mediates the co-culture of hepatocytes and endothelial cells

(2013) Yi Shang et al.   JOURNAL OF BIOSCIENCE AND BIOENGINEERING

Biomimetic design and fabrication of porous chitosan–gelatin liver scaffolds with hierarchical channel network

(2013) Haibo Gong et al.   JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE

Preparation and characterization of collagen/PLA, chitosan/PLA, and collagen/chitosan/PLA hybrid scaffolds for cartilage tissue engineering

(2013) Anne-Marie Haaparanta et al.   JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE

Effect of solid freeform fabrication-based polycaprolactone/poly(lactic-co-glycolic acid)/collagen scaffolds on cellular activities of human adipose-derived stem cells and rat primary hepatocytes

(2013) Jin-Hyung Shim et al.   JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE

Hydrogels with differential and patterned mechanics to study stiffness-mediated myofibroblastic differentiation of hepatic stellate cells

(2013) Murat Guvendiren et al.   Journal of the Mechanical Behavior of Biomedical Materials

Transplanted fibroblast cell sheets promote migration of hepatic progenitor cells in the incised host liver in allogeneic rat model

(2013) Izumi Muraoka et al.   Journal of Tissue Engineering and Regenerative Medicine

Regeneration-on-a-chip? The perspectives on use of microfluidics in regenerative medicine

(2013) Björn Harink et al.   LAB ON A CHIP

Chip-based liver equivalents for toxicity testing – organotypicalness versus cost-efficient high throughput

(2013) Eva-Maria Materne et al.   LAB ON A CHIP

Liver tissue engineering and cell sources: issues and challenges

(2013) Anwar A. Palakkan et al.   LIVER INTERNATIONAL

Polysaccharides and Their Derivatives for Versatile Tissue Engineering Application

(2013) Ferdous Khan et al.   MACROMOLECULAR BIOSCIENCE

Self-assembling functionalized nanopeptides for immediate hemostasis and accelerative liver tissue regeneration

(2013) Tzu-Yun Cheng et al.   Nanoscale

Acute Liver Failure

(2013) William Bernal et al.   NEW ENGLAND JOURNAL OF MEDICINE

Impact of Alginate Composition: From Bead Mechanical Properties to Encapsulated HepG2/C3A Cell Activities for In Vivo Implantation

(2013) Stephanie H. Capone et al.   PLoS One

Rapid Fabricating Technique for Multi-Layered Human Hepatic Cell Sheets by Forceful Contraction of the Fibroblast Monolayer

(2013) Yusuke Sakai et al.   PLoS One

Trans-differentiation of human mesenchymal stem cells generates functional hepatospheres on poly(l-lactic acid)-co-poly(ε-caprolactone)/collagen nanofibrous scaffolds

(2013) Dillip Kumar Bishi et al.   Journal of Materials Chemistry B

Human gelatin tissue-adhesive hydrogels prepared by enzyme-mediated biosynthesis of DOPA and Fe3+ion crosslinking

(2013) Young Chan Choi et al.   Journal of Materials Chemistry B

Silk fibroin biomaterials for tissue regenerations

(2012) Banani Kundu et al.   ADVANCED DRUG DELIVERY REVIEWS

Growth Factor Binding on Heparin Mimetic Peptide Nanofibers

(2012) Rashad Mammadov et al.   BIOMACROMOLECULES

Hepatocyte function within a stacked double sandwich culture plate cylindrical bioreactor for bioartificial liver system

(2012) Lei Xia et al.   BIOMATERIALS

The differentiation of MSCs into functional hepatocyte-like cells in a liver biomatrix scaffold and their transplantation into liver-fibrotic mice

(2012) Ru Ji et al.   BIOMATERIALS

Tissue specific synthetic ECM hydrogels for 3-D in vitro maintenance of hepatocyte function

(2012) Aleksander Skardal et al.   BIOMATERIALS

Engineering microscale topographies to control the cell–substrate interface

(2012) Mehdi Nikkhah et al.   BIOMATERIALS

Formation of model hepatocellular aggregates in a hydrogel scaffold using degradable genipin crosslinked gelatin microspheres as cell carriers

(2012) Ting Ting Lau et al.   Biomedical Materials

Role of biomaterials, therapeutic molecules and cells for hepatic tissue engineering

(2012) Kirthanashri Srinivasan Vasanthan et al.   BIOTECHNOLOGY ADVANCES

Liver tissue engineering: Recent advances in the development of a bio-artificial liver

(2012) Jung Seung Lee et al.   BIOTECHNOLOGY AND BIOPROCESS ENGINEERING

Hyaluronic acid based scaffolds for tissue engineering—A review

(2012) Maurice N. Collins et al.   CARBOHYDRATE POLYMERS

Cell Shape Regulation Based on Hepatocyte Sheet Engineering Technologies

(2012) Soichi Takagi et al.   CELL TRANSPLANTATION

Transplantation of Co-Microencapsulated Hepatocytes and HUVECs for Treatment of Fulminant Hepatic Failure

(2012) Liyuan Qiu et al.   INTERNATIONAL JOURNAL OF ARTIFICIAL ORGANS

Decellularized liver as a practical scaffold with a vascular network template for liver tissue engineering

(2012) Nana Shirakigawa et al.   JOURNAL OF BIOSCIENCE AND BIOENGINEERING

Heparin-conjugated gelatin as a growth factor immobilization scaffold

(2012) Shintaro Nakamura et al.   JOURNAL OF BIOSCIENCE AND BIOENGINEERING

Synthesis and characterization of disulfide-crosslinked alginate hydrogel scaffolds

(2012) Yanyan Zhao et al.   Materials Science & Engineering C-Materials for Biological Applications

Human Hepatocyte Growth Factor (hHGF)-Modified Hepatic Oval Cells Improve Liver Transplant Survival

(2012) Zhu Li et al.   PLoS One

Hyaluronic acid-based hydrogels: from a natural polysaccharide to complex networks

(2012) Xian Xu et al.   Soft Matter

The possibility of microbial cellulose for dressing and scaffold materials

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