Repurposing approved drugs on the pathway to novel therapies

The association of serum IFN-λ3 levels with hepatocarcinogenesis in chronic hepatitis C patients treated with direct-acting antiviral agents

(2019) Emi Inoue-Shinomiya et al.   HEPATOLOGY RESEARCH

Assessment of Clinical Response to Janus Kinase Inhibition in Patients With Familial Chilblain Lupus and TREX1 Mutation

(2019) Nick Zimmermann et al.   JAMA Dermatology

The STING agonist 5,6-dimethylxanthenone-4-acetic acid (DMXAA) stimulates an antiviral state and protects mice against herpes simplex virus-induced neurological disease

(2019) Stacey Cerón et al.   VIROLOGY

Drug combinations: a strategy to extend the life of antibiotics in the 21st century

(2019) Mike Tyers et al.   NATURE REVIEWS MICROBIOLOGY

Small-molecule ion channels increase host defences in cystic fibrosis airway epithelia

(2019) Katrina A. Muraglia et al.   NATURE

Use of nonsteroidal anti-inflammatory drugs predicts improved patient survival for PIK3CA-altered head and neck cancer

(2019) Matthew L. Hedberg et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Post-Injury Neuroprotective Effects of the Thalidomide Analog 3,6′-Dithiothalidomide on Traumatic Brain Injury

(2019) Buyandelger Batsaikhan et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Hypomethylation of STAT1 and HLA-DRB1 is associated with type-I interferon-dependent HLA-DRB1 expression in lupus CD8+ T cells

(2019) Shaylynn Miller et al.   ANNALS OF THE RHEUMATIC DISEASES

Mechanism of Inhibition of Ebola Virus RNA-Dependent RNA Polymerase by Remdesivir

(2019) Egor Tchesnokov et al.   Viruses-Basel

Repurposing of gamma interferon via inhalation delivery

(2018) Gerald C. Smaldone   ADVANCED DRUG DELIVERY REVIEWS

Treatment of Clostridium difficile Infection with a Small-Molecule Inhibitor of Toxin UDP-Glucose Hydrolysis Activity

(2018) Ilana L. Stroke et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Antiviral and anti-inflammatory activity of budesonide against human rhinovirus infection mediated via autophagy activation

(2018) Seong-Ryeol Kim et al.   ANTIVIRAL RESEARCH

Favipiravir (T-705) but not ribavirin is effective against two distinct strains of Crimean-Congo hemorrhagic fever virus in mice

(2018) David W. Hawman et al.   ANTIVIRAL RESEARCH

Repurposing the clinically approved calcium antagonist manidipine dihydrochloride as a new early inhibitor of human cytomegalovirus targeting the Immediate-Early 2 (IE2) protein

(2018) Beatrice Mercorelli et al.   ANTIVIRAL RESEARCH

Sustained antiviral effects and clearance of hepatitis surface antigen after combination therapy with entecavir and pegylated interferon in chronic hepatitis B

(2018) Satoru Hagiwara et al.   ANTIVIRAL THERAPY

The exoribonuclease Xrn1 is a post-transcriptional negative regulator of autophagy

(2018) Elizabeth Delorme-Axford et al.   Autophagy

Demarcation of Viral Shelters Results in Destruction by Membranolytic GTPases: Antiviral Function of Autophagy Proteins and Interferon-Inducible GTPases

(2018) Hailey M. Brown et al.   BIOESSAYS

Dexpramipexole as an Oral Steroid-sparing Agent in Hypereosinophilic Syndromes

(2018) Sandhya R. Panch et al.   BLOOD

Interferon alpha as antiviral therapy in chronic active Epstein-Barr virus disease with interstitial pneumonia - case report

(2018) Jacek Roliński et al.   BMC INFECTIOUS DISEASES

The poor design of clinical trials of statins in oncology may explain their failure – Lessons for drug repurposing

(2018) Marwan I. Abdullah et al.   CANCER TREATMENT REVIEWS

Fenofibrate and Telmisartan in the Management of Abdominal Aortic Aneurysm

(2018) Sophie E. Rowbotham et al.   CURRENT DRUG TARGETS

Structure-based identification of a NEDD8-activating enzyme inhibitor via drug repurposing

(2018) Ke-Jia Wu et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Pegylated interferon alpha 2a for the treatment of hepatitis C virus infection

(2018) Ashly Maughan et al.   Expert Opinion on Drug Metabolism & Toxicology

Ibuprofen as a template molecule for drug design against Ebola virus

(2018) Veljjko Veljkovic   Frontiers in Bioscience-Landmark

HBV Bypasses the Innate Immune Response and Does Not Protect HCV From Antiviral Activity of Interferon

(2018) Pascal Mutz et al.   GASTROENTEROLOGY

In-vitro activity of the novel fluorocycline eravacycline against carbapenem non-susceptible Acinetobacter baumannii

(2018) Harald Seifert et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

JAK-STAT signaling pathway inhibition: a role for treatment of discoid lupus erythematosus and dermatomyositis

(2018) Jared S. Kahn et al.   INTERNATIONAL JOURNAL OF DERMATOLOGY

In Vitro and In Vivo Activity of Amiodarone Against Ebola Virus

(2018) Julie Dyall et al.   JOURNAL OF INFECTIOUS DISEASES

The antimalarial drug amodiaquine possesses anti-ZIKA virus activities

(2018) Yingshan Han et al.   JOURNAL OF MEDICAL VIROLOGY

Safety and Efficacy of Rose Bengal Derivatives for Glial Scar Ablation in Chronic Spinal Cord Injury

(2018) Nandadevi Patil et al.   JOURNAL OF NEUROTRAUMA

Intralesional PV-10 for the treatment of in-transit melanoma metastases-Results of a prospective, non-randomized, single center study

(2018) Tavis A. Read et al.   JOURNAL OF SURGICAL ONCOLOGY

Screening and Identification of Lassa Virus Entry Inhibitors from an FDA-Approved Drugs Library

(2018) Peilin Wang et al.   JOURNAL OF VIROLOGY

Respiratory syncytial virus activates epidermal growth factor receptor to suppress interferon regulatory factor 1-dependent interferon-lambda and antiviral defense in airway epithelium

(2018) A Kalinowski et al.   Mucosal Immunology

Repurposing drugs for use against Zika virus infection

(2018) J. Devillers   SAR AND QSAR IN ENVIRONMENTAL RESEARCH

The Continuing Challenge of Metallo-β-Lactamase Inhibition: Mechanism Matters

(2018) Lin-Cheng Ju et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Structural basis of thalidomide enantiomer binding to cereblon

(2018) Tomoyuki Mori et al.   Scientific Reports

Identification of disulfiram as a secretase-modulating compound with beneficial effects on Alzheimer’s disease hallmarks

(2018) Sven Reinhardt et al.   Scientific Reports

Antiviral efficacy of favipiravir against Ebola virus: A translational study in cynomolgus macaques

(2018) Jérémie Guedj et al.   PLOS MEDICINE

STING agonists enable antiviral cross-talk between human cells and confer protection against genital herpes in mice

(2018) Morten K. Skouboe et al.   PLoS Pathogens

Human cytomegalovirus UL23 inhibits transcription of interferon-γ stimulated genes and blocks antiviral interferon-γ responses by interacting with human N-myc interactor protein

(2018) Linyuan Feng et al.   PLoS Pathogens

A new mechanism of interferon’s antiviral action: Induction of autophagy, essential for paramyxovirus replication, is inhibited by the interferon stimulated gene, TDRD7

(2018) Gayatri Subramanian et al.   PLoS Pathogens

Exploring Additional Dimensions of Complexity in Inhibitor Design for Serine β-Lactamases: Mechanistic and Intra- and Inter-molecular Chemistry Approaches

(2018) Focco van den Akker et al.   Frontiers in Microbiology

Inhibition of adenovirus infection by mifepristone

(2018) José A. Marrugal-Lorenzo et al.   ANTIVIRAL RESEARCH

Zika virus infection activates Sting-dependent antiviral autophagy in the Drosophila brain

(2018) Yuan Liu et al.   Autophagy

Polyglutamine Repeats in Viruses

(2018) Catherine H. Schein   MOLECULAR NEUROBIOLOGY

Drug repurposing of quinine as antiviral against dengue virus infection

(2018) Shilu Malakar et al.   VIRUS RESEARCH

Multiple Sclerosis-Secondary Progressive Multi-Arm Randomisation Trial (MS-SMART): a multiarm phase IIb randomised, double-blind, placebo-controlled clinical trial comparing the efficacy of three neuroprotective drugs in secondary progressive multiple sclerosis

(2018) Peter Connick et al.   BMJ Open

Siderophore Conjugates of Daptomycin are Potent Inhibitors of Carbapenem Resistant Strains of Acinetobacter baumannii

(2018) Manuka Ghosh et al.   ACS Infectious Diseases

Microbiological Profile of Sarecycline, a Novel Targeted Spectrum Tetracycline for the Treatment of Acne Vulgaris

(2018) George Zhanel et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Atorvastatin Treatment of Cavernous Angiomas with Symptomatic Hemorrhage Exploratory Proof of Concept (AT CASH EPOC) Trial

(2018) Sean P Polster et al.   NEUROSURGERY

Omadacycline Enters the Ring: A New Antimicrobial Contender

(2018) Katie E. Barber et al.   PHARMACOTHERAPY

Combination Therapy with Oseltamivir and Favipiravir Delays Mortality but Does Not Prevent Oseltamivir Resistance in Immunodeficient Mice Infected with Pandemic A(H1N1) Influenza Virus

(2018) Mariana Baz et al.   Viruses-Basel

Deciphering the Evolution of Cephalosporin Resistance to Ceftolozane-Tazobactam in Pseudomonas aeruginosa

(2018) Melissa D. Barnes et al.   mBio

Impact of Delayed Appropriate Antibiotic Therapy on Patient Outcomes by Antibiotic Resistance Status From Serious Gram-negative Bacterial Infections

(2018) Nicole Gidaya Bonine et al.   AMERICAN JOURNAL OF THE MEDICAL SCIENCES

Biological and targeted therapies of systemic lupus erythematosus: evidence and the state of the art

(2017) Chi Chiu Mok   Expert Review of Clinical Immunology

Metformin as a repurposed therapy in advanced non-small cell lung cancer (NSCLC): results of a phase II trial

(2017) Anish B. Parikh et al.   INVESTIGATIONAL NEW DRUGS

Screening of FDA-Approved Drugs for Inhibitors of Japanese Encephalitis Virus Infection

(2017) Shaobo Wang et al.   JOURNAL OF VIROLOGY

Follow-up of sustained virological responders with hepatitis C and advanced liver disease after interferon/ribavirin-free treatment

(2017) Karin Kozbial et al.   LIVER INTERNATIONAL

The Drug Repurposing Hub: a next-generation drug library and information resource

(2017) Steven M Corsello et al.   NATURE MEDICINE

Investigating antimalarial drug interactions of emetine dihydrochloride hydrate using CalcuSyn-based interactivity calculations

(2017) Holly Matthews et al.   PLoS One

Favipiravir (T-705), a broad spectrum inhibitor of viral RNA polymerase

(2017) Yousuke FURUTA et al.   PROCEEDINGS OF THE JAPAN ACADEMY SERIES B-PHYSICAL AND BIOLOGICAL SCIENCES

Nasopharyngeal infection byStreptococcus pyogenesrequires superantigen-responsive Vβ-specific T cells

(2017) Joseph J. Zeppa et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Neurofibromatosis as a gateway to better treatment for a variety of malignancies

(2017) Annette C. Bakker et al.   PROGRESS IN NEUROBIOLOGY

Metformin to Augment Strength Training Effective Response in Seniors (MASTERS): study protocol for a randomized controlled trial

(2017) Doug E. Long et al.   Trials

Functional classification of protein toxins as a basis for bioinformatic screening

(2017) Surendra S. Negi et al.   Scientific Reports

PI3K-Akt-mTOR axis sustains rotavirus infection via the 4E-BP1 mediated autophagy pathway and represents an antiviral target

(2017) Yuebang Yin et al.   Virulence

Favipiravir pharmacokinetics in Ebola-Infected patients of the JIKI trial reveals concentrations lower than targeted

(2017) Thi Huyen Tram Nguyen et al.   PLoS Neglected Tropical Diseases

Hair Repigmentation During Immunotherapy Treatment With an Anti–Programmed Cell Death 1 and Anti–Programmed Cell Death Ligand 1 Agent for Lung Cancer

(2017) Noelia Rivera et al.   JAMA Dermatology

A standard database for drug repositioning

(2017) Adam S. Brown et al.   Scientific Data

Giving Drugs a Second Chance: Overcoming Regulatory and Financial Hurdles in Repurposing Approved Drugs As Cancer Therapeutics

(2017) J. Javier Hernandez et al.   Frontiers in Oncology

A staged screening of registered drugs highlights remyelinating drug candidates for clinical trials

(2017) C. Eleuteri et al.   Scientific Reports

Drug Repurposing Identifies Inhibitors of Oseltamivir-Resistant Influenza Viruses

(2016) Ju Bao et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Sifalimumab, an anti-interferon-α monoclonal antibody, in moderate to severe systemic lupus erythematosus: a randomised, double-blind, placebo-controlled study

(2016) Munther Khamashta et al.   ANNALS OF THE RHEUMATIC DISEASES

Distinct Effects of T-705 (Favipiravir) and Ribavirin on Influenza Virus Replication and Viral RNA Synthesis

(2016) Evelien Vanderlinden et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Allosteric inhibitors of Coxsackie virus A24 RNA polymerase

(2016) Catherine H. Schein et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Improving Drug Design: An Update on Recent Applications of Efficiency Metrics, Strategies for Replacing Problematic Elements, and Compounds in Nontraditional Drug Space

(2016) Nicholas A. Meanwell   CHEMICAL RESEARCH IN TOXICOLOGY

Review of Eravacycline, a Novel Fluorocycline Antibacterial Agent

(2016) George G. Zhanel et al.   DRUGS

Abelson Kinase Inhibitors Are Potent Inhibitors of Severe Acute Respiratory Syndrome Coronavirus and Middle East Respiratory Syndrome Coronavirus Fusion

(2016) Christopher M. Coleman et al.   JOURNAL OF VIROLOGY

Structural basis of lenalidomide-induced CK1α degradation by the CRL4CRBN ubiquitin ligase

(2016) Georg Petzold et al.   NATURE

How do the alkaloids emetine and homoharringtonine kill trypanosomes? An insight into their molecular modes of action

(2016) Sonja Krstin et al.   PHYTOMEDICINE

Effects of the potential lithium-mimetic, ebselen, on brain neurochemistry: a magnetic resonance spectroscopy study at 7 tesla

(2016) Charles Masaki et al.   PSYCHOPHARMACOLOGY

Antibiotic Adjuvants: Rescuing Antibiotics from Resistance

(2016) Gerard D. Wright   TRENDS IN MICROBIOLOGY

‘RE:fine drugs’: an interactive dashboard to access drug repurposing opportunities

(2016) Soheil Moosavinasab et al.   Database-The Journal of Biological Databases and Curation

Combinatorial strategies for combating invasive fungal infections

(2016) Michaela Spitzer et al.   Virulence

Can commonly prescribed drugs be repurposed for the prevention or treatment of Alzheimer's and other neurodegenerative diseases? Protocol for an observational cohort study in the UK Clinical Practice Research Datalink

(2016) Venexia M Walker et al.   BMJ Open

Cell-Based High-Throughput Screening Assay Identifies 2′,2′-Difluoro-2′-deoxycytidine Gemcitabine as a Potential Antipoliovirus Agent

(2016) Zhuoran Zhang et al.   ACS Infectious Diseases

The Recognition of Identical Ligands by Unrelated Proteins

(2015) Sarah Barelier et al.   ACS Chemical Biology

Studying a Drug-like, RNA-Focused Small Molecule Library Identifies Compounds That Inhibit RNA Toxicity in Myotonic Dystrophy

(2015) Suzanne G. Rzuczek et al.   ACS Chemical Biology

Bactericidal Activity of Pyrazinamide and Clofazimine Alone and in Combinations with Pretomanid and Bedaquiline

(2015) Andreas H. Diacon et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Repurposing of rutin for the inhibition of norovirus replication

(2015) Nicolas Chéron et al.   ARCHIVES OF VIROLOGY

Repurposing Kinase Inhibitors as Antiviral Agents to Control Influenza A Virus Replication

(2015) Olivia Perwitasari et al.   ASSAY AND DRUG DEVELOPMENT TECHNOLOGIES

Repurposing and Rescuing of Mibefradil, an Antihypertensive, for Cancer: A Case Study

(2015) Andrew J. Krouse et al.   ASSAY AND DRUG DEVELOPMENT TECHNOLOGIES

Post-HTS case report and structural alert: Promiscuous 4-aroyl-1,5-disubstituted-3-hydroxy-2 H -pyrrol-2-one actives verified by ALARM NMR

(2015) Jayme L. Dahlin et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Drug repurposing and emerging adjunctive treatments for schizophrenia

(2015) Jan Malte Bumb et al.   EXPERT OPINION ON PHARMACOTHERAPY

Identification of a Compound That Disrupts Binding of Amyloid-β to the Prion Protein Using a Novel Fluorescence-based Assay

(2015) Emmanuel Risse et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

ZINC 15 – Ligand Discovery for Everyone

(2015) Teague Sterling et al.   Journal of Chemical Information and Modeling

Loxapine Add-on for Adolescents and Adults with Autism Spectrum Disorders and Irritability

(2015) Jessica A. Hellings et al.   JOURNAL OF CHILD AND ADOLESCENT PSYCHOPHARMACOLOGY

Pyrimethamine Derivatives: Insight into Binding Mechanism and Improved Enhancement of Mutant β-N-acetylhexosaminidase Activity

(2015) Michael B. Tropak et al.   JOURNAL OF MEDICINAL CHEMISTRY

Dose regimen of favipiravir for Ebola virus disease

(2015) France Mentré et al.   LANCET INFECTIOUS DISEASES

Effect of cyclic, low dose pyrimethamine treatment in patients with Late Onset Tay Sachs: an open label, extended pilot study

(2015) Etty Osher et al.   Orphanet Journal of Rare Diseases

Structural basis of the broadly neutralizing anti-interferon-α antibody rontalizumab

(2015) Brigitte Maurer et al.   PROTEIN SCIENCE

A screen of approved drugs and molecular probes identifies therapeutics with anti–Ebola virus activity

(2015) Lisa M. Johansen et al.   Science Translational Medicine

Exploring the potential of adjunct therapy in tuberculosis

(2015) Geetha Vani Rayasam et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Sequence specificity for uridylylation of the viral peptide linked to the genome (VPg) of enteroviruses

(2015) Catherine H. Schein et al.   VIROLOGY

A phase Ib multiple ascending dose study of the safety, tolerability, and central nervous system availability of AZD0530 (saracatinib) in Alzheimer’s disease

(2015) Haakon B Nygaard et al.   Alzheimers Research & Therapy

High-Throughput Minigenome System for Identifying Small-Molecule Inhibitors of Ebola Virus Replication

(2015) Megan R. Edwards et al.   ACS Infectious Diseases

A phase I trial of the HIV protease inhibitor nelfinavir in adults with solid tumors

(2015) Gideon M. Blumenthal et al.   Oncotarget

Repurposing of Clinically Developed Drugs for Treatment of Middle East Respiratory Syndrome Coronavirus Infection

(2014) Julie Dyall et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Nitazoxanide: A first-in-class broad-spectrum antiviral agent

(2014) Jean-François Rossignol   ANTIVIRAL RESEARCH

Amodiaquine, an antimalarial drug, inhibits dengue virus type 2 replication and infectivity

(2014) Siwaporn Boonyasuppayakorn et al.   ANTIVIRAL RESEARCH

Immune reconstitution inflammatory syndrome associated with bacterial infections

(2014) Jean-Christophe Lagier et al.   Expert Opinion On Drug Safety

Mucosal Healing With Thalidomide in Refractory Crohn’s Disease Patients Intolerant of Anti-TNF-α Drugs

(2014) Maria Lia Scribano et al.   JOURNAL OF CLINICAL GASTROENTEROLOGY

Critical role of TNF-α in cerebral aneurysm formation and progression to rupture

(2014) Robert M Starke et al.   Journal of Neuroinflammation

Membrane Interaction and Functional Plasticity of Inositol Polyphosphate 5-Phosphatases

(2014) Werner Braun et al.   STRUCTURE

Cryo-EM structure of the Plasmodium falciparum 80S ribosome bound to the anti-protozoan drug emetine

(2014) Wilson Wong et al.   eLife

Favipiravir (T-705), a novel viral RNA polymerase inhibitor

(2013) Yousuke Furuta et al.   ANTIVIRAL RESEARCH

Cancer drug discovery by repurposing: teaching new tricks to old dogs

(2013) Subash C. Gupta et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Investigating drug repositioning opportunities in FDA drug labels through topic modeling

(2012) Halil Bisgin et al.   BMC BIOINFORMATICS

Towards a new tuberculosis drug: pyridomycin - nature's isoniazid

(2012) Ruben C. Hartkoorn et al.   EMBO Molecular Medicine

Novel approaches to flavivirus drug discovery

(2012) Carolyn Botting et al.   Expert Opinion on Drug Discovery

Inhibition of Cellular Autophagy Deranges Dengue Virion Maturation

(2012) Roberto Mateo et al.   JOURNAL OF VIROLOGY

Molecular mechanism of action of immune-modulatory drugs thalidomide, lenalidomide and pomalidomide in multiple myeloma

(2012) Yuan Xiao Zhu et al.   LEUKEMIA & LYMPHOMA

An orally available, small-molecule interferon inhibits viral replication

(2012) Hideyuki Konishi et al.   Scientific Reports

Pharmacophore Selection and Redesign of Non-nucleotide Inhibitors of Anthrax Edema Factor

(2012) Catherine H. Schein et al.   Toxins

Hair repigmentation associated with the use of lenalidomide: Graying may not be an irreversible process!

(2012) Constantin A Dasanu et al.   JOURNAL OF ONCOLOGY PHARMACY PRACTICE

Structure-based redesign of an edema toxin inhibitor

(2011) Deliang Chen et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Online chemical modeling environment (OCHEM): web platform for data storage, model development and publishing of chemical information

(2011) Iurii Sushko et al.   JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN

A Rapid, High-Throughput Viability Assay forBlastocystisspp. Reveals Metronidazole Resistance and Extensive Subtype-Dependent Variations in Drug Susceptibilities

(2010) Haris Mirza et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Testing the Efficacy and Toxicity of Adenylyl Cyclase Inhibitors against Enteric Pathogens Using In Vitro and In Vivo Models of Infection

(2010) S. T. Moen et al.   INFECTION AND IMMUNITY

An open-label Phase I/II clinical trial of pyrimethamine for the treatment of patients affected with chronic GM2 gangliosidosis (Tay–Sachs or Sandhoff variants)

(2010) Joe T.R. Clarke et al.   MOLECULAR GENETICS AND METABOLISM

NMR solution structure of poliovirus uridylyated peptide linked to the genome (VPgpU)

(2010) Catherine H. Schein et al.   PEPTIDES

Inhibition of matrix metalloproteinase activity in vivo protects against vascular hyporeactivity in endotoxemia

(2009) Jonathan J. Cena et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

The Role of Doxycycline as a Matrix Metalloproteinase Inhibitor for the Treatment of Chronic Wounds

(2009) J. Stechmiller et al.   Biological Research for Nursing

Novel inhibitors of anthrax edema factor

(2008) Deliang Chen et al.   BIOORGANIC & MEDICINAL CHEMISTRY