Towards a new tuberculosis drug: pyridomycin - nature's isoniazid

Overview of theCCP4 suite and current developments

(2011) Martyn D. Winn et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Novel Inhibitors of InhA Efficiently KillMycobacterium tuberculosisunder Aerobic and Anaerobic Conditions

(2011) Catherine Vilchèze et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

New tuberculosis drugs on the horizon

(2011) Stewart T Cole et al.   CURRENT OPINION IN MICROBIOLOGY

Identification and Characterization of the Pyridomycin Biosynthetic Gene Cluster ofStreptomyces pyridomyceticusNRRL B-2517

(2011) Tingting Huang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

XDS

(2010) Wolfgang Kabsch   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Simple Model for Testing Drugs against Nonreplicating Mycobacterium tuberculosis

(2010) C. Sala et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Broad-Spectrum Antibiotic Activity of the Arylomycin Natural Products Is Masked by Natural Target Mutations

(2010) Peter A. Smith et al.   CHEMISTRY & BIOLOGY

From HIV to Tuberculosis and Back Again: A Tale of Activism in 2 Pandemics

(2010) Mark Harrington   CLINICAL INFECTIOUS DISEASES

Extensively Drug‐Resistant Tuberculosis: “There must be some kind of way out of here”

(2010) J. Peter Cegielski   CLINICAL INFECTIOUS DISEASES

Phosphorylation of InhA inhibits mycolic acid biosynthesis and growth of Mycobacterium tuberculosis

(2010) Virginie Molle et al.   MOLECULAR MICROBIOLOGY

Novel targets in M. tuberculosis: search for new drugs

(2010) Gyanu Lamichhane   TRENDS IN MOLECULAR MEDICINE

Triclosan Derivatives: Towards Potent Inhibitors of Drug-Sensitive and Drug-ResistantMycobacterium tuberculosis

(2009) Joel S. Freundlich et al.   ChemMedChem

Global Burden and Epidemiology of Tuberculosis

(2009) Philippe Glaziou et al.   CLINICS IN CHEST MEDICINE

Antibiotics for Emerging Pathogens

(2009) M. A. Fischbach et al.   SCIENCE

Inhibitors of FabI, an Enzyme Drug Target in the Bacterial Fatty Acid Biosynthesis Pathway

(2008) Hao Lu et al.   ACCOUNTS OF CHEMICAL RESEARCH

Membrane lipid homeostasis in bacteria

(2008) Yong-Mei Zhang et al.   NATURE REVIEWS MICROBIOLOGY