Investigating drug repositioning opportunities in FDA drug labels through topic modeling

Mining FDA drug labels using an unsupervised learning technique - topic modeling

(2011) Halil Bisgin et al.   BMC BIOINFORMATICS

Drug repositioning for orphan diseases

(2011) D. Sardana et al.   BRIEFINGS IN BIOINFORMATICS

Exploiting drug-disease relationships for computational drug repositioning

(2011) J. T. Dudley et al.   BRIEFINGS IN BIOINFORMATICS

Structure-based systems biology for analyzing off-target binding

(2011) Lei Xie et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

In silico repositioning of approved drugs for rare and neglected diseases

(2011) Sean Ekins et al.   DRUG DISCOVERY TODAY

FDA-approved drug labeling for the study of drug-induced liver injury

(2011) Minjun Chen et al.   DRUG DISCOVERY TODAY

A Machine Learning-Based Method To Improve Docking Scoring Functions and Its Application to Drug Repurposing

(2011) Sarah L. Kinnings et al.   Journal of Chemical Information and Modeling

Use of ibuprofen and risk of Parkinson disease

(2011) X. Gao et al.   NEUROLOGY

Finding Complex Biological Relationships in Recent PubMed Articles Using Bio-LDA

(2011) Huijun Wang et al.   PLoS One

Network Neighbors of Drug Targets Contribute to Drug Side-Effect Similarity

(2011) Lucas Brouwers et al.   PLoS One

Mining Relational Paths in Integrated Biomedical Data

(2011) Bing He et al.   PLoS One

Systematic Drug Repositioning Based on Clinical Side-Effects

(2011) Lun Yang et al.   PLoS One

The NCGC Pharmaceutical Collection: A Comprehensive Resource of Clinically Approved Drugs Enabling Repurposing and Chemical Genomics

(2011) R. Huang et al.   Science Translational Medicine

Computational Repositioning of the Anticonvulsant Topiramate for Inflammatory Bowel Disease

(2011) J. T. Dudley et al.   Science Translational Medicine

Event extraction for systems biology by text mining the literature

(2010) Sophia Ananiadou et al.   TRENDS IN BIOTECHNOLOGY

Literature Mining for the Discovery of Hidden Connections between Drugs, Genes and Diseases

(2010) Raoul Frijters et al.   PLoS Computational Biology

Mapping Adverse Drug Reactions in Chemical Space

(2009) Josef Scheiber et al.   JOURNAL OF MEDICINAL CHEMISTRY

Drug Target Identification Using Side-Effect Similarity

(2008) M. Campillos et al.   SCIENCE