Repurposing of Clinically Developed Drugs for Treatment of Middle East Respiratory Syndrome Coronavirus Infection

Screening of an FDA-Approved Compound Library Identifies Four Small-Molecule Inhibitors of Middle East Respiratory Syndrome Coronavirus Replication in Cell Culture

(2014) Adriaan H. de Wilde et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Ribavirin and interferon therapy in patients infected with the Middle East respiratory syndrome coronavirus: an observational study

(2014) Jaffar A. Al-Tawfiq et al.   INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES

Rapid generation of a mouse model for Middle East respiratory syndrome

(2014) Jincun Zhao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Middle East Respiratory Syndrome Coronavirus Infection in Dromedary Camels in Saudi Arabia

(2014) A. N. Alagaili et al.   mBio

Seroepidemiology for MERS coronavirus using microneutralisation and pseudoparticle virus neutralisation assays reveal a high prevalence of antibody in dromedary camels in Egypt, June 2013

(2013) R Perera et al.   Eurosurveillance

Interferon-  and mycophenolic acid are potent inhibitors of Middle East respiratory syndrome coronavirus in cell-based assays

(2013) B. J. Hart et al.   JOURNAL OF GENERAL VIROLOGY

Broad-spectrum antivirals for the emerging Middle East respiratory syndrome coronavirus

(2013) Jasper F.W. Chan et al.   JOURNAL OF INFECTION

Middle East Respiratory Syndrome Coronavirus (MERS-CoV): Announcement of the Coronavirus Study Group

(2013) R. J. de Groot et al.   JOURNAL OF VIROLOGY

Middle East respiratory syndrome coronavirus neutralising serum antibodies in dromedary camels: a comparative serological study

(2013) Chantal BEM Reusken et al.   LANCET INFECTIOUS DISEASES

Molecular basis of binding between novel human coronavirus MERS-CoV and its receptor CD26

(2013) Guangwen Lu et al.   NATURE

Dipeptidyl peptidase 4 is a functional receptor for the emerging human coronavirus-EMC

(2013) V. Stalin Raj et al.   NATURE

Treatment with interferon-α2b and ribavirin improves outcome in MERS-CoV–infected rhesus macaques

(2013) Darryl Falzarano et al.   NATURE MEDICINE

Multiple Cationic Amphiphiles Induce a Niemann-Pick C Phenotype and Inhibit Ebola Virus Entry and Infection

(2013) Charles J. Shoemaker et al.   PLoS One

A Systematic Screen of FDA-Approved Drugs for Inhibitors of Biological Threat Agents

(2013) Peter B. Madrid et al.   PLoS One

FDA-Approved Selective Estrogen Receptor Modulators Inhibit Ebola Virus Infection

(2013) L. M. Johansen et al.   Science Translational Medicine

Salinomycin induces cell death via inactivation of Stat3 and downregulation of Skp2

(2013) K H Koo et al.   Cell Death & Disease

Inhibition of novel β coronavirus replication by a combination of interferon-α2b and ribavirin

(2013) Darryl Falzarano et al.   Scientific Reports

Tyrosine Kinase Inhibitors for the Treatment of Chronic Myeloid Leukemia

(2012) Manlio Tolomeo et al.   Anti-Cancer Agents in Medicinal Chemistry

Polyether ionophores—promising bioactive molecules for cancer therapy

(2012) Adam Huczyński   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Isolation of a Novel Coronavirus from a Man with Pneumonia in Saudi Arabia

(2012) Ali M. Zaki et al.   NEW ENGLAND JOURNAL OF MEDICINE

Productive Replication of Ebola Virus Is Regulated by the c-Abl1 Tyrosine Kinase

(2012) M. Garcia et al.   Science Translational Medicine

Inhibition of severe acute respiratory syndrome coronavirus replication in a lethal SARS-CoV BALB/c mouse model by stinging nettle lectin, Urtica dioica agglutinin

(2011) Yohichi Kumaki et al.   ANTIVIRAL RESEARCH

Variola and Monkeypox Viruses Utilize Conserved Mechanisms of Virion Motility and Release That Depend on Abl and Src Family Tyrosine Kinases

(2010) P. M. Reeves et al.   JOURNAL OF VIROLOGY

Identification of Selective Inhibitors of Cancer Stem Cells by High-Throughput Screening

(2009) Piyush B. Gupta et al.   CELL

A Benefit-Risk Assessment of Imatinib in Chronic Myeloid Leukaemia and Gastrointestinal Stromal Tumours

(2009) Dominik Wolf et al.   DRUG SAFETY

Synergistic drug combinations tend to improve therapeutically relevant selectivity

(2009) Joseph Lehár et al.   NATURE BIOTECHNOLOGY

Cathepsin L Functionally Cleaves the Severe Acute Respiratory Syndrome Coronavirus Class I Fusion Protein Upstream of Rather than Adjacent to the Fusion Peptide

(2008) B. J. Bosch et al.   JOURNAL OF VIROLOGY