Respiratory syncytial virus activates epidermal growth factor receptor to suppress interferon regulatory factor 1-dependent interferon-lambda and antiviral defense in airway epithelium

Respiratory syncytial virus infection induces a subset of types I and III interferons in human dendritic cells

(2017) Philippa Hillyer et al.   VIROLOGY

EGFR Interacts with the Fusion Protein of Respiratory Syncytial Virus Strain 2-20 and Mediates Infection and Mucin Expression

(2016) Michael G. Currier et al.   PLoS Pathogens

Influenza induces IL-8 and GM-CSF secretion by human alveolar epithelial cells through HGF/c-Met and TGF-α/EGFR signaling

(2015) Yoko Ito et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Amphiregulin promotes the immunosuppressive activity of intrahepatic CD4+regulatory T cells to impair CD8+T-cell immunity against hepatitis B virus infection

(2015) Kai Dai et al.   IMMUNOLOGY

Neutrophils in respiratory syncytial virus infection: A target for asthma prevention

(2015) Ruben J. Geerdink et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Induction and Antagonism of Antiviral Responses in Respiratory Syncytial Virus-Infected Pediatric Airway Epithelium

(2015) Rémi Villenave et al.   JOURNAL OF VIROLOGY

Neuropilin 1 is an entry factor that promotes EBV infection of nasopharyngeal epithelial cells

(2015) Hong-Bo Wang et al.   Nature Communications

DDX60 Is Involved in RIG-I-Dependent and Independent Antiviral Responses, and Its Function Is Attenuated by Virus-Induced EGFR Activation

(2015) Hiroyuki Oshiumi et al.   Cell Reports

Respiratory Syncytial Virus Uses CX3CR1 as a Receptor on Primary Human Airway Epithelial Cultures

(2015) Sara M. Johnson et al.   PLoS Pathogens

Immunostimulatory Defective Viral Genomes from Respiratory Syncytial Virus Promote a Strong Innate Antiviral Response during Infection in Mice and Humans

(2015) Yan Sun et al.   PLoS Pathogens

Lower respiratory tract infection caused by respiratory syncytial virus: current management and new therapeutics

(2015) Natalie I Mazur et al.   Lancet Respiratory Medicine

EGFR activation suppresses respiratory virus-induced IRF1-dependent CXCL10 production

(2014) April Kalinowski et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Dual Role of NOX2 in Respiratory Syncytial Virus- and Sendai Virus-Induced Activation of NF- B in Airway Epithelial Cells

(2014) K. Fink et al.   JOURNAL OF IMMUNOLOGY

Peroxisomal MAVS activates IRF1-mediated IFN-λ production

(2014) Siyuan Ding et al.   NATURE IMMUNOLOGY

Diverse intracellular pathogens activate type III interferon expression from peroxisomes

(2014) Charlotte Odendall et al.   NATURE IMMUNOLOGY

Updated Guidance for Palivizumab Prophylaxis Among Infants and Young Children at Increased Risk of Hospitalization for Respiratory Syncytial Virus Infection

(2014)   PEDIATRICS

An Overview of Respiratory Syncytial Virus

(2014) Jia Meng et al.   PLoS Pathogens

Respiratory virus–induced EGFR activation suppresses IRF1-dependent interferon λ and antiviral defense in airway epithelium

(2013) Iris F. Ueki et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Receptor Tyrosine Kinase Inhibitors That Block Replication of Influenza A and Other Viruses

(2011) Naveen Kumar et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Regulation of IFN- 1 Promoter Activity (IFN- 1/IL-29) in Human Airway Epithelial Cells

(2011) R. Siegel et al.   JOURNAL OF IMMUNOLOGY

Receptor Tyrosine Kinase Inhibitors Block Multiple Steps of Influenza A Virus Replication

(2011) N. Kumar et al.   JOURNAL OF VIROLOGY

Identification of nucleolin as a cellular receptor for human respiratory syncytial virus

(2011) Farnoosh Tayyari et al.   NATURE MEDICINE

Respiratory Syncytial Virus Infection in Adults

(2011) Edward Walsh   SEMINARS IN RESPIRATORY AND CRITICAL CARE MEDICINE

Type-III interferon, not type-I, is the predominant interferon induced by respiratory viruses in nasal epithelial cells

(2011) Tamaki Okabayashi et al.   VIRUS RESEARCH

Dissection of the Influenza A Virus Endocytic Routes Reveals Macropinocytosis as an Alternative Entry Pathway

(2011) Erik de Vries et al.   PLoS Pathogens

Inhibition of poxvirus spreading by the anti-tumor drug Gefitinib (Iressa™)

(2010) Stefan Langhammer et al.   ANTIVIRAL RESEARCH

Rhinovirus induces MUC5AC in a human infection model and in vitro via NF- B and EGFR pathways

(2010) C. A. Hewson et al.   EUROPEAN RESPIRATORY JOURNAL

Respiratory Syncytial Virus F and G Proteins Induce Interleukin 1α, CC, and CXC Chemokine Responses by Normal Human Bronchoepithelial Cells

(2010) Christine M. Oshansky et al.   JOURNAL OF INFECTIOUS DISEASES

Lambda Interferon Renders Epithelial Cells of the Respiratory and Gastrointestinal Tracts Resistant to Viral Infections

(2010) M. Mordstein et al.   JOURNAL OF VIROLOGY

Lambda Interferon Is the Predominant Interferon Induced by Influenza A Virus Infection In Vivo

(2010) N. A. Jewell et al.   JOURNAL OF VIROLOGY

Respiratory virus induction of alpha-, beta- and lambda-interferons in bronchial epithelial cells and peripheral blood mononuclear cells

(2009) M. R. Khaitov et al.   ALLERGY

Safety and Efficacy of an Inhaled Epidermal Growth Factor Receptor Inhibitor (BIBW 2948 BS) in Chronic Obstructive Pulmonary Disease

(2009) Prescott G. Woodruff et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Selective Transcriptional Down-Regulation of Human Rhinovirus-Induced Production of CXCL10 from Airway Epithelial Cells via the MEK1 Pathway

(2009) R. S. Zaheer et al.   JOURNAL OF IMMUNOLOGY

Role of Double-Stranded RNA Pattern Recognition Receptors in Rhinovirus-Induced Airway Epithelial Cell Responses

(2009) Q. Wang et al.   JOURNAL OF IMMUNOLOGY

Multiple TLRs activate EGFR via a signaling cascade to produce innate immune responses in airway epithelium

(2008) Jonathan L. Koff et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Epidermal Growth Factor Receptor Signaling to Erk1/2 and STATs Control the Intensity of the Epithelial Inflammatory Responses to Rhinovirus Infection

(2008) Kenneth Liu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY