Myelin in the Central Nervous System: Structure, Function, and Pathology

Deep gray matter volume loss drives disability worsening in multiple sclerosis

(2018) Arman Eshaghi et al.   ANNALS OF NEUROLOGY

Inflammatory intrathecal profiles and cortical damage in multiple sclerosis

(2018) Roberta Magliozzi et al.   ANNALS OF NEUROLOGY

Thalamic atrophy in multiple sclerosis: A magnetic resonance imaging marker of neurodegeneration throughout disease

(2018) Christina J. Azevedo et al.   ANNALS OF NEUROLOGY

Pathogenicity of human antibodies against myelin oligodendrocyte glycoprotein

(2018) Melania Spadaro et al.   ANNALS OF NEUROLOGY

Myelin Plasticity and Nervous System Function

(2018) Michelle Monje   Annual Review of Neuroscience

Spatiotemporal distribution of fibrinogen in marmoset and human inflammatory demyelination

(2018) Nathanael J Lee et al.   BRAIN

Progression of regional grey matter atrophy in multiple sclerosis

(2018) Arman Eshaghi et al.   BRAIN

The compartmentalized inflammatory response in the multiple sclerosis brain is composed of tissue-resident CD8+ T lymphocytes and B cells

(2018) Joana Machado-Santos et al.   BRAIN

Evidence for Myelin Sheath Remodeling in the CNS Revealed by In Vivo Imaging

(2018) Franziska Auer et al.   CURRENT BIOLOGY

Aberrant astrocyte Ca2+ signals “AxCa signals” exacerbate pathological alterations in an Alexander disease model

(2018) Kozo Saito et al.   GLIA

MOG encephalomyelitis: international recommendations on diagnosis and antibody testing

(2018) S. Jarius et al.   Journal of Neuroinflammation

Diffusion tensor imaging in metachromatic leukodystrophy

(2018) Diane F. van Rappard et al.   JOURNAL OF NEUROLOGY

Diagnosis of multiple sclerosis: 2017 revisions of the McDonald criteria

(2018) Alan J Thompson et al.   LANCET NEUROLOGY

Myelin remodeling through experience-dependent oligodendrogenesis in the adult somatosensory cortex

(2018) Ethan G. Hughes et al.   NATURE NEUROSCIENCE

Lifelong cortical myelin plasticity and age-related degeneration in the live mammalian brain

(2018) Robert A. Hill et al.   NATURE NEUROSCIENCE

Adulthood leukodystrophies

(2018) Wolfgang Köhler et al.   Nature Reviews Neurology

Time to separate MOG-Ab-associated disease from AQP4-Ab-positive neuromyelitis optica spectrum disorder

(2018) Yael Hacohen et al.   NEUROLOGY

Multiple Sclerosis

(2018) Daniel S. Reich et al.   NEW ENGLAND JOURNAL OF MEDICINE

Defective cholesterol clearance limits remyelination in the aged central nervous system

(2018) Ludovico Cantuti-Castelvetri et al.   SCIENCE

Pharmacogenetic stimulation of neuronal activity increases myelination in an axon-specific manner

(2018) Stanislaw Mitew et al.   Nature Communications

Oligodendrocytes control potassium accumulation in white matter and seizure susceptibility

(2018) Valerie A Larson et al.   eLife

Association of MOG-IgG Serostatus With Relapse After Acute Disseminated Encephalomyelitis and Proposed Diagnostic Criteria for MOG-IgG–Associated Disorders

(2018) A. Sebastian López-Chiriboga et al.   JAMA Neurology

Differences in the Reponses to Apheresis Therapy of Patients With 3 Histopathologically Classified Immunopathological Patterns of Multiple Sclerosis

(2018) Lidia Stork et al.   JAMA Neurology

White matter changes in Alzheimer’s disease: a focus on myelin and oligodendrocytes

(2018) Sara E. Nasrabady et al.   Acta Neuropathologica Communications

Teaching Case 5-2018: Integrated morphological and immunological work-up of neurosurgical specimen allows accurate diagnosis of neuroinflammatory lesions: an example of acute disseminated encephalomyelitis (ADEM) associated with anti-MOG antibodies

(2018) Julia Lang et al.   CLINICAL NEUROPATHOLOGY

Cortical neuronal densities and cerebral white matter demyelination in multiple sclerosis: a retrospective study

(2018) Bruce D Trapp et al.   LANCET NEUROLOGY

Accumulation of 8,9-unsaturated sterols drives oligodendrocyte formation and remyelination

(2018) Zita Hubler et al.   NATURE

Microglial TREM2/DAP12 Signaling: A Double-Edged Sword in Neural Diseases

(2018) Hiroyuki Konishi et al.   Frontiers in Cellular Neuroscience

Oligodendrocyte-encoded Kir4.1 function is required for axonal integrity

(2018) Lucas Schirmer et al.   eLife

Regulation of myelin structure and conduction velocity by perinodal astrocytes

(2018) Dipankar J. Dutta et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Acutely damaged axons are remyelinated in multiple sclerosis and experimental models of demyelination

(2017) Verena Schultz et al.   GLIA

Regulation and dysregulation of axon infrastructure by myelinating glia

(2017) Simon Pan et al.   JOURNAL OF CELL BIOLOGY

Oligodendroglia: metabolic supporters of neurons

(2017) Thomas Philips et al.   JOURNAL OF CLINICAL INVESTIGATION

Microglia in steady state

(2017) Katrin Kierdorf et al.   JOURNAL OF CLINICAL INVESTIGATION

Human antibodies against the myelin oligodendrocyte glycoprotein can cause complement-dependent demyelination

(2017) Patrick Peschl et al.   Journal of Neuroinflammation

Relationship of acute axonal damage, Wallerian degeneration, and clinical disability in multiple sclerosis

(2017) Shailender Singh et al.   Journal of Neuroinflammation

Uncoupling of UNC5C with Polymerized TUBB3 in Microtubules Mediates Netrin-1 Repulsion

(2017) Qiangqiang Shao et al.   JOURNAL OF NEUROSCIENCE

Clemastine fumarate as a remyelinating therapy for multiple sclerosis (ReBUILD): a randomised, controlled, double-blind, crossover trial

(2017) Ari J Green et al.   LANCET

Safety and efficacy of opicinumab in acute optic neuritis (RENEW): a randomised, placebo-controlled, phase 2 trial

(2017) Diego Cadavid et al.   LANCET NEUROLOGY

Neuromyelitis Spectrum Disorders

(2017) Brian G. Weinshenker et al.   MAYO CLINIC PROCEEDINGS

Ca2+ activity signatures of myelin sheath formation and growth in vivo

(2017) Marion Baraban et al.   NATURE NEUROSCIENCE

Regulation of developing myelin sheath elongation by oligodendrocyte calcium transients in vivo

(2017) Anna M. Krasnow et al.   NATURE NEUROSCIENCE

Biomolecular condensates: organizers of cellular biochemistry

(2017) Salman F. Banani et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

ER stress and the unfolded protein response in neurodegeneration

(2017) Claudio Hetz et al.   Nature Reviews Neurology

Axo-myelinic neurotransmission: a novel mode of cell signalling in the central nervous system

(2017) I. Micu et al.   NATURE REVIEWS NEUROSCIENCE

Regenerating CNS myelin — from mechanisms to experimental medicines

(2017) Robin J. M. Franklin et al.   NATURE REVIEWS NEUROSCIENCE

Wrapped to Adapt: Experience-Dependent Myelination

(2017) Christopher W. Mount et al.   NEURON

Fibrinogen Activates BMP Signaling in Oligodendrocyte Progenitor Cells and Inhibits Remyelination after Vascular Damage

(2017) Mark A. Petersen et al.   NEURON

Neuronal loss, demyelination and volume change in the multiple sclerosis neocortex

(2017) D. Carassiti et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Autoantibody-induced internalization of CNS AQP4 water channel and EAAT2 glutamate transporter requires astrocytic Fc receptor

(2017) Shannon R. Hinson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Rapid and efficient generation of oligodendrocytes from human induced pluripotent stem cells using transcription factors

(2017) Marc Ehrlich et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Glucose-regulated protein 78 autoantibody associates with blood-brain barrier disruption in neuromyelitis optica

(2017) Fumitaka Shimizu et al.   Science Translational Medicine

BCAS1 expression defines a population of early myelinating oligodendrocytes in multiple sclerosis lesions

(2017) Maryam K. Fard et al.   Science Translational Medicine

The Genetics of Multiple Sclerosis: From 0 to 200 in 50 Years

(2017) Sergio E. Baranzini et al.   TRENDS IN GENETICS

All Wrapped Up: Environmental Effects on Myelination

(2017) Thomas A. Forbes et al.   TRENDS IN NEUROSCIENCES

Antagonistic Functions of MBP and CNP Establish Cytosolic Channels in CNS Myelin

(2017) Nicolas Snaidero et al.   Cell Reports

Oligodendroglial myelination requires astrocyte-derived lipids

(2017) Nutabi Camargo et al.   PLOS BIOLOGY

Signalling through AMPA receptors on oligodendrocyte precursors promotes myelination by enhancing oligodendrocyte survival

(2017) Eleni Kougioumtzidou et al.   eLife

The paranodal cytoskeleton clusters Na+ channels at nodes of Ranvier

(2017) Veronique Amor et al.   eLife

Alexander Disease Mutations Produce Cells with Coexpression of Glial Fibrillary Acidic Protein and NG2 in Neurosphere Cultures and Inhibit Differentiation into Mature Oligodendrocytes

(2017) Ulises Gómez-Pinedo et al.   Frontiers in Neurology

The origin of Rosenthal fibers and their contributions to astrocyte pathology in Alexander disease

(2017) Alexander A. Sosunov et al.   Acta Neuropathologica Communications

Membrane Association Landscape of Myelin Basic Protein Portrays Formation of the Myelin Major Dense Line

(2017) Arne Raasakka et al.   Scientific Reports

Slow expansion of multiple sclerosis iron rim lesions: pathology and 7 T magnetic resonance imaging

(2016) Assunta Dal-Bianco et al.   ACTA NEUROPATHOLOGICA

Multiple sclerosis: experimental models and reality

(2016) Hans Lassmann et al.   ACTA NEUROPATHOLOGICA

An updated histological classification system for multiple sclerosis lesions

(2016) Tanja Kuhlmann et al.   ACTA NEUROPATHOLOGICA

Benzothiazole and stilbene derivatives as promising positron emission tomography myelin radiotracers for multiple sclerosis

(2016) Benedetta Bodini et al.   ANNALS OF NEUROLOGY

In vivo imaging reveals rapid astrocyte depletion and axon damage in a model of neuromyelitis optica-related pathology

(2016) Marina Herwerth et al.   ANNALS OF NEUROLOGY

Dynamic Imaging of Individual Remyelination Profiles in Multiple Sclerosis

(2016) Benedetta Bodini et al.   ANNALS OF NEUROLOGY

Anti-MOG antibody: The history, clinical phenotype, and pathogenicity of a serum biomarker for demyelination

(2016) Sudarshini Ramanathan et al.   AUTOIMMUNITY REVIEWS

The topograpy of demyelination and neurodegeneration in the multiple sclerosis brain

(2016) Lukas Haider et al.   BRAIN

Hypomyelinating leukodystrophies - a molecular insight into the white matter pathology

(2016) A. Charzewska et al.   CLINICAL GENETICS

Individual Neuronal Subtypes Exhibit Diversity in CNS Myelination Mediated by Synaptic Vesicle Release

(2016) Sigrid Koudelka et al.   CURRENT BIOLOGY

Myelination

(2016) J.L. Salzer et al.   CURRENT BIOLOGY

The force awakens: insights into the origin and formation of microglia

(2016) Tuan Leng Tay et al.   CURRENT OPINION IN NEUROBIOLOGY

Epigenetic control of oligodendrocyte development: adding new players to old keepers

(2016) Jia Liu et al.   CURRENT OPINION IN NEUROBIOLOGY

The multifaceted role of astrocytes in regulating myelination

(2016) Hülya Kıray et al.   EXPERIMENTAL NEUROLOGY

The history of myelin

(2016) Anne Isabelle Boullerne   EXPERIMENTAL NEUROLOGY

Complement C3 on microglial clusters in multiple sclerosis occur in chronic but not acute disease: Implication for disease pathogenesis

(2016) Iliana Michailidou et al.   GLIA

Astrocytes are central in the pathomechanisms of vanishing white matter

(2016) Stephanie Dooves et al.   JOURNAL OF CLINICAL INVESTIGATION

MOG-IgG in NMO and related disorders: a multicenter study of 50 patients. Part 1: Frequency, syndrome specificity, influence of disease activity, long-term course, association with AQP4-IgG, and origin

(2016) Sven Jarius et al.   Journal of Neuroinflammation

White matter and cognition: making the connection

(2016) Christopher M. Filley et al.   JOURNAL OF NEUROPHYSIOLOGY

Cyclic AMP and Polyamines Overcome Inhibition by Myelin-Associated Glycoprotein through eIF5A-Mediated Increases in p35 Expression and Activation of Cdk5

(2016) H. He et al.   JOURNAL OF NEUROSCIENCE

Identification of the Kappa-Opioid Receptor as a Therapeutic Target for Oligodendrocyte Remyelination

(2016) Feng Mei et al.   JOURNAL OF NEUROSCIENCE

MRI criteria for the diagnosis of multiple sclerosis: MAGNIMS consensus guidelines

(2016) Massimo Filippi et al.   LANCET NEUROLOGY

Atypical inflammatory demyelinating syndromes of the CNS

(2016) Todd A Hardy et al.   LANCET NEUROLOGY

Effector T-cell trafficking between the leptomeninges and the cerebrospinal fluid

(2016) Christian Schläger et al.   NATURE

Origin, fate and dynamics of macrophages at central nervous system interfaces

(2016) Tobias Goldmann et al.   NATURE IMMUNOLOGY

Rapid production of new oligodendrocytes is required in the earliest stages of motor-skill learning

(2016) Lin Xiao et al.   NATURE NEUROSCIENCE

Age-related myelin degradation burdens the clearance function of microglia during aging

(2016) Shima Safaiyan et al.   NATURE NEUROSCIENCE

Remodeling myelination: implications for mechanisms of neural plasticity

(2016) Kae-Jiun Chang et al.   NATURE NEUROSCIENCE

Advanced MRI and staging of multiple sclerosis lesions

(2016) Martina Absinta et al.   Nature Reviews Neurology

Hereditary diffuse leukoencephalopathy with axonal spheroids (HDLS): update on molecular genetics

(2016) Carmen Stabile et al.   NEUROLOGICAL SCIENCES

Acute disseminated encephalomyelitis

(2016) Daniela Pohl et al.   NEUROLOGY

Oligodendroglial NMDA Receptors Regulate Glucose Import and Axonal Energy Metabolism

(2016) Aiman S. Saab et al.   NEURON

Somatodendritic Expression of JAM2 Inhibits Oligodendrocyte Myelination

(2016) Stephanie A. Redmond et al.   NEURON

Novel pathologic findings in patients with Pelizaeus-Merzbacher disease

(2016) Jeremy J. Laukka et al.   NEUROSCIENCE LETTERS

JC Polyomavirus Abundance and Distribution in Progressive Multifocal Leukoencephalopathy (PML) Brain Tissue Implicates Myelin Sheath in Intracerebral Dissemination of Infection

(2016) Keith A. Wharton et al.   PLoS One

Ultrastructural anatomy of nodes of Ranvier in the peripheral nervous system as revealed by STED microscopy

(2016) Elisa D’Este et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Epidemiology of Multiple Sclerosis: From Risk Factors to Prevention—An Update

(2016) Kassandra Munger et al.   SEMINARS IN NEUROLOGY

Emerging Roles for CSF-1 Receptor and its Ligands in the Nervous System

(2016) Violeta Chitu et al.   TRENDS IN NEUROSCIENCES

Myelinating satellite oligodendrocytes are integrated in a glial syncytium constraining neuronal high-frequency activity

(2016) Arne Battefeld et al.   Nature Communications

Structural basis of myelin-associated glycoprotein adhesion and signalling

(2016) Matti F. Pronker et al.   Nature Communications

Subcortical cytoskeleton periodicity throughout the nervous system

(2016) Elisa D’Este et al.   Scientific Reports

Loss of Myelin Basic Protein Function Triggers Myelin Breakdown in Models of Demyelinating Diseases

(2016) Marie-Theres Weil et al.   Cell Reports

Kif13b Regulates PNS and CNS Myelination through the Dlg1 Scaffold

(2016) Roberta Noseda et al.   PLOS BIOLOGY

PI(3,5)P2 biosynthesis regulates oligodendrocyte differentiation by intrinsic and extrinsic mechanisms

(2016) Yevgeniya A Mironova et al.   eLife

A large fraction of neocortical myelin ensheathes axons of local inhibitory neurons

(2016) Kristina D Micheva et al.   eLife

Septin/anillin filaments scaffold central nervous system myelin to accelerate nerve conduction

(2016) Julia Patzig et al.   eLife

Tamoxifen accelerates the repair of demyelinated lesions in the central nervous system

(2016) Ginez A. Gonzalez et al.   Scientific Reports

Astrocyte pathology in Alexander disease causes a marked inflammatory environment

(2015) Markel Olabarria et al.   ACTA NEUROPATHOLOGICA

Astrocytes: a central element in neurological diseases

(2015) Milos Pekny et al.   ACTA NEUROPATHOLOGICA

Cerebrovascular disease in ageing and Alzheimer’s disease

(2015) Seth Love et al.   ACTA NEUROPATHOLOGICA

TREM2 regulates microglial cell activation in response to demyelination in vivo

(2015) Claudia Cantoni et al.   ACTA NEUROPATHOLOGICA

Clinical and pathological insights into the dynamic nature of the white matter multiple sclerosis plaque

(2015) Josa M. Frischer et al.   ANNALS OF NEUROLOGY

Persistence and pathogenesis of the neurotropic polyomavirus JC

(2015) Hassen S. Wollebo et al.   ANNALS OF NEUROLOGY

Metachromatic leukodystrophy: Disease spectrum and approaches for treatment

(2015) Diane F. van Rappard et al.   BEST PRACTICE & RESEARCH CLINICAL ENDOCRINOLOGY & METABOLISM

Metabolism and functions of lipids in myelin

(2015) Sebastian Schmitt et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Claudin-11 Tight Junctions in Myelin Are a Barrier to Diffusion and Lack Strong Adhesive Properties

(2015) Andrew R. Denninger et al.   BIOPHYSICAL JOURNAL

Reconstruction of single cortical projection neurons reveals primary spine loss in multiple sclerosis

(2015) Tanja Jürgens et al.   BRAIN

CNS Myelin Sheath Lengths Are an Intrinsic Property of Oligodendrocytes

(2015) Marie E. Bechler et al.   CURRENT BIOLOGY

How to make an oligodendrocyte

(2015) S. A. Goldman et al.   DEVELOPMENT

Glia in mammalian development and disease

(2015) J. Bradley Zuchero et al.   DEVELOPMENT

CNS Myelin Wrapping Is Driven by Actin Disassembly

(2015) J. Bradley Zuchero et al.   DEVELOPMENTAL CELL

Actin Filament Turnover Drives Leading Edge Growth during Myelin Sheath Formation in the Central Nervous System

(2015) Schanila Nawaz et al.   DEVELOPMENTAL CELL

Oligodendrocyte generation during mouse development

(2015) Hirohide Takebayashi et al.   GLIA

NG2-glia and their functions in the central nervous system

(2015) L. Dimou et al.   GLIA

Mutation Update ofARSAandPSAPGenes Causing Metachromatic Leukodystrophy

(2015) Martina Cesani et al.   HUMAN MUTATION

Animal Models for Progressive Multifocal Leukoencephalopathy

(2015) Martyn K. White et al.   JOURNAL OF CELLULAR PHYSIOLOGY

TREM2 sustains microglial expansion during aging and response to demyelination

(2015) Pietro Luigi Poliani et al.   JOURNAL OF CLINICAL INVESTIGATION

Anti-MOG antibodies are present in a subgroup of patients with a neuromyelitis optica phenotype

(2015) Anne-Katrin Pröbstel et al.   Journal of Neuroinflammation

Pathologic Staging of White Matter Lesions in Adult-Onset Leukoencephalopathy/Leukodystrophy With Axonal Spheroids

(2015) Murad Alturkustani et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Triggering Receptor Expressed on Myeloid Cells 2 (TREM2) Deficiency Attenuates Phagocytic Activities of Microglia and Exacerbates Ischemic Damage in Experimental Stroke

(2015) M. Kawabori et al.   JOURNAL OF NEUROSCIENCE

CNS myelin sheath is stochastically built by homotypic fusion of myelin membranes within the bounds of an oligodendrocyte process

(2015) Sara Szuchet et al.   JOURNAL OF STRUCTURAL BIOLOGY

Pathological mechanisms in progressive multiple sclerosis

(2015) Don H Mahad et al.   LANCET NEUROLOGY

Environmental risk factors and multiple sclerosis: an umbrella review of systematic reviews and meta-analyses

(2015) Lazaros Belbasis et al.   LANCET NEUROLOGY

Case definition and classification of leukodystrophies and leukoencephalopathies

(2015) Adeline Vanderver et al.   MOLECULAR GENETICS AND METABOLISM

Anti-MOG antibodies plead against MS diagnosis in an Acquired Demyelinating Syndromes cohort

(2015) Immy A Ketelslegers et al.   Multiple Sclerosis Journal

Drug-based modulation of endogenous stem cells promotes functional remyelination in vivo

(2015) Fadi J. Najm et al.   NATURE

The leukodystrophy protein FAM126A (hyccin) regulates PtdIns(4)P synthesis at the plasma membrane

(2015) Jeremy M. Baskin et al.   NATURE CELL BIOLOGY

Synaptic vesicle release regulates myelin sheath number of individual oligodendrocytes in vivo

(2015) Sigrid Mensch et al.   NATURE NEUROSCIENCE

Neuronal activity biases axon selection for myelination in vivo

(2015) Jacob H Hines et al.   NATURE NEUROSCIENCE

Cell type– and brain region–resolved mouse brain proteome

(2015) Kirti Sharma et al.   NATURE NEUROSCIENCE

Synaptopathy connects inflammation and neurodegeneration in multiple sclerosis

(2015) Georgia Mandolesi et al.   Nature Reviews Neurology

Phenotypic characterization of a Csf1r haploinsufficient mouse model of adult-onset leukodystrophy with axonal spheroids and pigmented glia (ALSP)

(2015) Violeta Chitu et al.   NEUROBIOLOGY OF DISEASE

International consensus diagnostic criteria for neuromyelitis optica spectrum disorders

(2015) Dean M. Wingerchuk et al.   NEUROLOGY

Acceleration of conduction velocity linked to clustering of nodal components precedes myelination

(2015) Sean A. Freeman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Nodes of Ranvier: Molecular Assembly and Maintenance

(2015) Matthew N. Rasband et al.   Cold Spring Harbor Perspectives in Biology

Oligodendrocytes: Myelination and Axonal Support

(2015) Mikael Simons et al.   Cold Spring Harbor Perspectives in Biology

Transcriptional and Epigenetic Regulation of Oligodendrocyte Development and Myelination in the Central Nervous System

(2015) Ben Emery et al.   Cold Spring Harbor Perspectives in Biology

STED Nanoscopy Reveals the Ubiquity of Subcortical Cytoskeleton Periodicity in Living Neurons

(2015) Elisa D’Este et al.   Cell Reports

The Polarity Protein Scribble Regulates Myelination and Remyelination in the Central Nervous System

(2015) Andrew A. Jarjour et al.   PLOS BIOLOGY

Anti-MOG antibodies plead against MS diagnosis in an Acquired Demyelinating Syndromes cohort

(2015) Immy A Ketelslegers et al.   Multiple Sclerosis Journal

Common neuropathological features underlie distinct clinical presentations in three siblings with hereditary diffuse leukoencephalopathy with spheroids caused by CSF1R p.Arg782His

(2015) John L. Robinson et al.   Acta Neuropathologica Communications

Induction of a common microglia gene expression signature by aging and neurodegenerative conditions: a co-expression meta-analysis

(2015) Inge R Holtman et al.   Acta Neuropathologica Communications

Oligodendroglia in cortical multiple sclerosis lesions decrease with disease progression, but regenerate after repeated experimental demyelination

(2014) Enrique Garea Rodriguez et al.   ACTA NEUROPATHOLOGICA

Hyperintense cortical signal on magnetic resonance imaging reflects focal leukocortical encephalitis and seizure risk in progressive multifocal leukoencephalopathy

(2014) Michael N. Khoury et al.   ANNALS OF NEUROLOGY

Myelination of the Nervous System: Mechanisms and Functions

(2014) Klaus-Armin Nave et al.   Annual Review of Cell and Developmental Biology

Adaptive autophagy in Alexander disease-affected astrocytes

(2014) Guomei Tang et al.   Autophagy

The emerging functions of oligodendrocytes in regulating neuronal network behaviour

(2014) Livia de Hoz et al.   BIOESSAYS

Dynamics of Oligodendrocyte Generation and Myelination in the Human Brain

(2014) Maggie S.Y. Yeung et al.   CELL

Myelin Membrane Wrapping of CNS Axons by PI(3,4,5)P3-Dependent Polarized Growth at the Inner Tongue

(2014) Nicolas Snaidero et al.   CELL

A unified cell biological perspective on axon–myelin injury

(2014) Mikael Simons et al.   JOURNAL OF CELL BIOLOGY

Human glial chimeric mice reveal astrocytic dependence of JC virus infection

(2014) Yoichi Kondo et al.   JOURNAL OF CLINICAL INVESTIGATION

The Major Myelin-Resident Protein PLP Is Transported to Myelin Membranes via a Transcytotic Mechanism: Involvement of Sulfatide

(2014) Wia Baron et al.   MOLECULAR AND CELLULAR BIOLOGY

Micropillar arrays as a high-throughput screening platform for therapeutics in multiple sclerosis

(2014) Feng Mei et al.   NATURE MEDICINE

A hierarchy of ankyrin-spectrin complexes clusters sodium channels at nodes of Ranvier

(2014) Tammy Szu-Yu Ho et al.   NATURE NEUROSCIENCE

Glial ankyrins facilitate paranodal axoglial junction assembly

(2014) Kae-Jiun Chang et al.   NATURE NEUROSCIENCE

Modulation of oligodendrocyte generation during a critical temporal window after NG2 cell division

(2014) Robert A Hill et al.   NATURE NEUROSCIENCE

Defining the clinical course of multiple sclerosis: The 2013 revisions

(2014) F. D. Lublin et al.   NEUROLOGY

Astrocyte-Derived Endothelin-1 Inhibits Remyelination through Notch Activation

(2014) Timothy R. Hammond et al.   NEURON

Pervasive Axonal Transport Deficits in Multiple Sclerosis Models

(2014) Catherine Diamante Sorbara et al.   NEURON

Pelizaeus-Merzbacher disease: Cellular pathogenesis and pharmacologic therapy

(2014) Tomohiro Torii et al.   PEDIATRICS INTERNATIONAL

Contactin-1 regulates myelination and nodal/paranodal domain organization in the central nervous system

(2014) G. Colakoglu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Neuronal Activity Promotes Oligodendrogenesis and Adaptive Myelination in the Mammalian Brain

(2014) E. M. Gibson et al.   SCIENCE

Distinct Profiles of Myelin Distribution Along Single Axons of Pyramidal Neurons in the Neocortex

(2014) G. S. Tomassy et al.   SCIENCE

Motor skill learning requires active central myelination

(2014) I. A. McKenzie et al.   SCIENCE

Axon-glia interaction and membrane traffic in myelin formation

(2014) Robin White et al.   Frontiers in Cellular Neuroscience

Neuregulin and BDNF Induce a Switch to NMDA Receptor-Dependent Myelination by Oligodendrocytes

(2014) Iben Lundgaard et al.   PLOS BIOLOGY

Early loss of oligodendrocytes in human and experimental neuromyelitis optica lesions

(2013) Claudia Wrzos et al.   ACTA NEUROPATHOLOGICA

Microglial nodules in early multiple sclerosis white matter are associated with degenerating axons

(2013) Shailender Singh et al.   ACTA NEUROPATHOLOGICA

C1q-targeted monoclonal antibody prevents complement-dependent cytotoxicity and neuropathology in in vitro and mouse models of neuromyelitis optica

(2013) Puay-Wah Phuan et al.   ACTA NEUROPATHOLOGICA

Involvement of antibody-dependent cell-mediated cytotoxicity in inflammatory demyelination in a mouse model of neuromyelitis optica

(2013) Julien Ratelade et al.   ACTA NEUROPATHOLOGICA

Presence of six different lesion types suggests diverse mechanisms of tissue injury in neuromyelitis optica

(2013) Tatsuro Misu et al.   ACTA NEUROPATHOLOGICA

Insufficient OPC migration into demyelinated lesions is a cause of poor remyelination in MS and mouse models

(2013) Amanda Boyd et al.   ACTA NEUROPATHOLOGICA

Oligodendrocyte Progenitor Cell Susceptibility to Injury in Multiple Sclerosis

(2013) Qiao-Ling Cui et al.   AMERICAN JOURNAL OF PATHOLOGY

Iron and neurodegeneration in the multiple sclerosis brain

(2013) Simon Hametner et al.   ANNALS OF NEUROLOGY

In vivo labeling of peroxisomes by photoconvertible mEos2 in myelinating glia of mice

(2013) Sarah Richert et al.   BIOCHIMIE

Hyaluronan accumulation and arrested oligodendrocyte progenitor maturation in vanishing white matter disease

(2013) Marianna Bugiani et al.   BRAIN

Disease-specific molecular events in cortical multiple sclerosis lesions

(2013) Marie Therese Fischer et al.   BRAIN

Axonal selection and myelin sheath generation in the central nervous system

(2013) Mikael Simons et al.   CURRENT OPINION IN CELL BIOLOGY

The role of myelin and oligodendrocytes in axonal energy metabolism

(2013) Aiman S Saab et al.   CURRENT OPINION IN NEUROBIOLOGY

Individual Oligodendrocytes Have Only a Few Hours in which to Generate New Myelin Sheaths In Vivo

(2013) Tim Czopka et al.   DEVELOPMENTAL CELL

Uncoupling of neuroinflammation from axonal degeneration in mice lacking the myelin protein tetraspanin-2

(2013) Patricia de Monasterio-Schrader et al.   GLIA

A critical role for the cholesterol-associated proteolipids PLP and M6B in myelination of the central nervous system

(2013) Hauke B. Werner et al.   GLIA

Membrane domain organization of myelinated axons requires βII spectrin

(2013) Chuansheng Zhang et al.   JOURNAL OF CELL BIOLOGY

Eosinophil pathogenicity mechanisms and therapeutics in neuromyelitis optica

(2013) Hua Zhang et al.   JOURNAL OF CLINICAL INVESTIGATION

Colony-stimulating factor 1 receptor (CSF1R) signaling in injured neurons facilitates protection and survival

(2013) Jian Luo et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Neuroprotective intervention by interferon-γ blockade prevents CD8+T cell–mediated dendrite and synapse loss

(2013) Mario Kreutzfeldt et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Different Stages of White Matter Changes in the Original HDLS Family Revealed by Advanced MRI Techniques

(2013) Christina Sundal et al.   JOURNAL OF NEUROIMAGING

Phenotypic Conversions of "Protoplasmic" to "Reactive" Astrocytes in Alexander Disease

(2013) A. A. Sosunov et al.   JOURNAL OF NEUROSCIENCE

Sustained Activation of ERK1/2 MAPK in Oligodendrocytes and Schwann Cells Enhances Myelin Growth and Stimulates Oligodendrocyte Progenitor Expansion

(2013) A. Ishii et al.   JOURNAL OF NEUROSCIENCE

Motor Skill Learning Induces Changes in White Matter Microstructure and Myelination

(2013) C. Sampaio-Baptista et al.   JOURNAL OF NEUROSCIENCE

Early Musical Training and White-Matter Plasticity in the Corpus Callosum: Evidence for a Sensitive Period

(2013) C. J. Steele et al.   JOURNAL OF NEUROSCIENCE

GJC2 promoter mutations causing Pelizaeus–Merzbacher-like disease

(2013) Leo Gotoh et al.   MOLECULAR GENETICS AND METABOLISM

A regenerative approach to the treatment of multiple sclerosis

(2013) Vishal A. Deshmukh et al.   NATURE

M2 microglia and macrophages drive oligodendrocyte differentiation during CNS remyelination

(2013) Veronique E Miron et al.   NATURE NEUROSCIENCE

The microglial sensome revealed by direct RNA sequencing

(2013) Suzanne E Hickman et al.   NATURE NEUROSCIENCE

Oligodendrocyte progenitors balance growth with self-repulsion to achieve homeostasis in the adult brain

(2013) Ethan G Hughes et al.   NATURE NEUROSCIENCE

In situ evidence of JC virus control by CD8+ T cells in PML-IRIS during HIV infection

(2013) G. Martin-Blondel et al.   NEUROLOGY

Three Mechanisms Assemble Central Nervous System Nodes of Ranvier

(2013) Keiichiro Susuki et al.   NEURON

Oligodendrocyte Dynamics in the Healthy Adult CNS: Evidence for Myelin Remodeling

(2013) Kaylene M. Young et al.   NEURON

White matter astrocytes in health and disease

(2013) I. Lundgaard et al.   NEUROSCIENCE

Physiological Roles of Aquaporin-4 in Brain

(2013) Erlend A. Nagelhus et al.   PHYSIOLOGICAL REVIEWS

Loss of electrostatic cell-surface repulsion mediates myelin membrane adhesion and compaction in the central nervous system

(2013) M. Bakhti et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Concepts for regulation of axon integrity by enwrapping glia

(2013) Bogdan Beirowski   Frontiers in Cellular Neuroscience

Myelin Membrane Assembly Is Driven by a Phase Transition of Myelin Basic Proteins Into a Cohesive Protein Meshwork

(2013) Shweta Aggarwal et al.   PLOS BIOLOGY

Neurotransmitter-Triggered Transfer of Exosomes Mediates Oligodendrocyte–Neuron Communication

(2013) Carsten Frühbeis et al.   PLOS BIOLOGY

Neuromyelitis optica lesions may inform multiple sclerosis heterogeneity debate

(2012) Wolfgang Brück et al.   ANNALS OF NEUROLOGY

Oligodendrocytes and the early multiple sclerosis lesion

(2012) John W. Prineas et al.   ANNALS OF NEUROLOGY

Cortical remyelination: A new target for repair therapies in multiple sclerosis

(2012) Ansi Chang et al.   ANNALS OF NEUROLOGY

Gap junction communication in myelinating glia

(2012) Anna Nualart-Marti et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Meningeal inflammation plays a role in the pathology of primary progressive multiple sclerosis

(2012) Sung R. Choi et al.   BRAIN

Molecular Biology, Epidemiology, and Pathogenesis of Progressive Multifocal Leukoencephalopathy, the JC Virus-Induced Demyelinating Disease of the Human Brain

(2012) M. W. Ferenczy et al.   CLINICAL MICROBIOLOGY REVIEWS

The CSF-1 receptor ligands IL-34 and CSF-1 exhibit distinct developmental brain expression patterns and regulate neural progenitor cell maintenance and maturation

(2012) Sayan Nandi et al.   DEVELOPMENTAL BIOLOGY

Organization of myelin in the mouse somatosensory barrel cortex and the effects of sensory deprivation

(2012) Kyrstle Barrera et al.   Developmental Neurobiology

White Matter Structure Changes as Adults Learn a Second Language

(2012) Alexander A. Schlegel et al.   JOURNAL OF COGNITIVE NEUROSCIENCE

Contrasting disease patterns in seropositive and seronegative neuromyelitis optica: A multicentre study of 175 patients

(2012) Sven Jarius et al.   Journal of Neuroinflammation

Fibroblast Growth Factor Receptor Signaling in Oligodendrocytes Regulates Myelin Sheath Thickness

(2012) M. Furusho et al.   JOURNAL OF NEUROSCIENCE

Alexander Disease

(2012) A. Messing et al.   JOURNAL OF NEUROSCIENCE

Megalencephalic leukoencephalopathy with subcortical cysts: chronic white matter oedema due to a defect in brain ion and water homoeostasis

(2012) Marjo S van der Knaap et al.   LANCET NEUROLOGY

Association between pathological and MRI findings in multiple sclerosis

(2012) Massimo Filippi et al.   LANCET NEUROLOGY

Acute disseminated encephalomyelitis followed by recurrent or monophasic optic neuritis in pediatric patients

(2012) Peter Huppke et al.   Multiple Sclerosis Journal

Oligodendroglia metabolically support axons and contribute to neurodegeneration

(2012) Youngjin Lee et al.   NATURE

Glycolytic oligodendrocytes maintain myelin and long-term axonal integrity

(2012) Ursula Fünfschilling et al.   NATURE

A culture system to study oligodendrocyte myelination processes using engineered nanofibers

(2012) Seonok Lee et al.   NATURE METHODS

Impaired adult myelination in the prefrontal cortex of socially isolated mice

(2012) Jia Liu et al.   NATURE NEUROSCIENCE

Myelin-oligodendrocyte glycoprotein antibodies in adults with a neuromyelitis optica phenotype

(2012) J. Kitley et al.   NEUROLOGY

Time-Lapse Imaging of the Dynamics of CNS Glial-Axonal Interactions In Vitro and Ex Vivo

(2012) Kalliopi Ioannidou et al.   PLoS One

Actin, Spectrin, and Associated Proteins Form a Periodic Cytoskeletal Structure in Axons

(2012) K. Xu et al.   SCIENCE

A Critical Period for Social Experience-Dependent Oligodendrocyte Maturation and Myelination

(2012) M. Makinodan et al.   SCIENCE

Pathology of immune reconstitution inflammatory syndrome in multiple sclerosis with natalizumab-associated progressive multifocal leukoencephalopathy

(2011) Imke Metz et al.   ACTA NEUROPATHOLOGICA

Multiple sclerosis normal-appearing white matter: Pathology-imaging correlations

(2011) Natalia M. Moll et al.   ANNALS OF NEUROLOGY

Neutrophil protease inhibition reduces neuromyelitis optica-immunoglobulin G-induced damage in mouse brain

(2011) Samira Saadoun et al.   ANNALS OF NEUROLOGY

Gap junctions in inherited human disorders of the central nervous system

(2011) Charles K. Abrams et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

A mouse model for eukaryotic translation initiation factor 2B-leucodystrophy reveals abnormal development of brain white matter

(2011) Michal Geva et al.   BRAIN

Class 3 semaphorins influence oligodendrocyte precursor recruitment and remyelination in adult central nervous system

(2011) Gabrièle Piaton et al.   BRAIN

Human neural progenitors from different foetal forebrain regions remyelinate the adult mouse spinal cord

(2011) Delphine Buchet et al.   BRAIN

Meningeal inflammation is widespread and linked to cortical pathology in multiple sclerosis

(2011) Owain W. Howell et al.   BRAIN

N-WASp is required for Schwann cell cytoskeletal dynamics, normal myelin gene expression and peripheral nerve myelination

(2011) Fuzi Jin et al.   DEVELOPMENT

CNS live imaging reveals a new mechanism of myelination: The liquid croissant model

(2011) Bettina Sobottka et al.   GLIA

Progenitors in the adult cerebral cortex: Cell cycle properties and regulation by physiological stimuli and injury

(2011) Christiane Simon et al.   GLIA

N-WASP is required for membrane wrapping and myelination by Schwann cells

(2011) Nurit Novak et al.   JOURNAL OF CELL BIOLOGY

Translation of myelin basic protein mRNA in oligodendrocytes is regulated by integrin activation and hnRNP-K

(2011) Lisbeth S. Laursen et al.   JOURNAL OF CELL BIOLOGY

Frequent Infection of Cortical Neurons by JC Virus in Patients With Progressive Multifocal Leukoencephalopathy

(2011) Christian Wüthrich et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Inhibition of CNS Remyelination by the Presence of Semaphorin 3A

(2011) Y. A. Syed et al.   JOURNAL OF NEUROSCIENCE

NMDA Receptor Signaling in Oligodendrocyte Progenitors Is Not Required for Oligodendrogenesis and Myelination

(2011) L. M. De Biase et al.   JOURNAL OF NEUROSCIENCE

The ERK2 Mitogen-Activated Protein Kinase Regulates the Timing of Oligodendrocyte Differentiation

(2011) S. L. Fyffe-Maricich et al.   JOURNAL OF NEUROSCIENCE

Astrocytic Tissue Inhibitor of Metalloproteinase-1 (TIMP-1) Promotes Oligodendrocyte Differentiation and Enhances CNS Myelination

(2011) C. S. Moore et al.   JOURNAL OF NEUROSCIENCE

Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis

(2011) Stephen Sawcer et al.   NATURE

Mutations in the colony stimulating factor 1 receptor (CSF1R) gene cause hereditary diffuse leukoencephalopathy with spheroids

(2011) Rosa Rademakers et al.   NATURE GENETICS

A reversible form of axon damage in experimental autoimmune encephalomyelitis and multiple sclerosis

(2011) Ivana Nikić et al.   NATURE MEDICINE

Bidirectional plasticity of calcium-permeable AMPA receptors in oligodendrocyte lineage cells

(2011) Marzieh Zonouzi et al.   NATURE NEUROSCIENCE

GFAP mutations, age at onset, and clinical subtypes in Alexander disease

(2011) M. Prust et al.   NEUROLOGY

Nodes of Ranvier Act as Barriers to Restrict Invasion of Flanking Paranodal Domains in Myelinated Axons

(2011) Courtney Thaxton et al.   NEURON

Absence of Colony Stimulation Factor-1 Receptor Results in Loss of Microglia, Disrupted Brain Development and Olfactory Deficits

(2011) Bryna Erblich et al.   PLoS One

Molecular outcomes of neuromyelitis optica (NMO)-IgG binding to aquaporin-4 in astrocytes

(2011) S. R. Hinson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Neurite outgrowth inhibitor Nogo-A establishes spatial segregation and extent of oligodendrocyte myelination

(2011) S. Y. C. Chong et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Control of Local Protein Synthesis and Initial Events in Myelination by Action Potentials

(2011) H. Wake et al.   SCIENCE

Central nervous system myelin: structure, synthesis and assembly

(2011) Shweta Aggarwal et al.   TRENDS IN CELL BIOLOGY

Progressive multifocal leukoencephalopathy and promyelocytic leukemia nuclear bodies: a review of clinical, neuropathological, and virological aspects of JC virus-induced demyelinating disease

(2010) Yukiko Shishido-Hara   ACTA NEUROPATHOLOGICA

Influence of White Matter Hyperintensities on the Cognition of Patients With Parkinson Disease

(2010) Seung-Jae Lee et al.   ALZHEIMER DISEASE & ASSOCIATED DISORDERS

Meningeal T cells associate with diffuse axonal loss in multiple sclerosis spinal cords

(2010) Géraldine Androdias et al.   ANNALS OF NEUROLOGY

Mitochondrial DNA deletions and neurodegeneration in multiple sclerosis

(2010) Graham R. Campbell et al.   ANNALS OF NEUROLOGY

A Gradient of neuronal loss and meningeal inflammation in multiple sclerosis

(2010) Roberta Magliozzi et al.   ANNALS OF NEUROLOGY

Relevance of GJC2 promoter mutation in Pelizaeus-Merzbacher-like disease

(2010) Patricia Combes et al.   ANNALS OF NEUROLOGY

Perivenous demyelination: association with clinically defined acute disseminated encephalomyelitis and comparison with pathologically confirmed multiple sclerosis

(2010) N. P. Young et al.   BRAIN

Oligodendrocytes are damaged by neuromyelitis optica immunoglobulin G via astrocyte injury

(2010) Romain Marignier et al.   BRAIN

Inhibiting poly(ADP-ribose) polymerase: a potential therapy against oligodendrocyte death

(2010) S. Veto et al.   BRAIN

Intra-cerebral injection of neuromyelitis optica immunoglobulin G and human complement produces neuromyelitis optica lesions in mice

(2010) Samira Saadoun et al.   BRAIN

Demyelination versus remyelination in progressive multiple sclerosis

(2010) Stephan Bramow et al.   BRAIN

Wallerian Degeneration: A Major Component of Early Axonal Pathology in Multiple Sclerosis

(2010) Tomasz Dziedzic et al.   BRAIN PATHOLOGY

Axonal Loss and Neurofilament Phosphorylation Changes Accompany Lesion Development and Clinical Progression in Multiple Sclerosis

(2010) Lucas Schirmer et al.   BRAIN PATHOLOGY

Imaging manifestations of progressive multifocal leukoencephalopathy

(2010) R. Shah et al.   CLINICAL RADIOLOGY

Pelizaeus–Merzbacher-like disease is caused not only by a loss of connexin47 function but also by a hemichannel dysfunction

(2010) Simone Diekmann et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Inhibition of Myelin Membrane Sheath Formation by Oligodendrocyte-derived Exosome-like Vesicles

(2010) Mostafa Bakhti et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Oligomers of Mutant Glial Fibrillary Acidic Protein (GFAP) Inhibit the Proteasome System in Alexander Disease Astrocytes, and the Small Heat Shock Protein αB-Crystallin Reverses the Inhibition

(2010) Guomei Tang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Critical Role for Ceramide Synthase 2 in Liver Homeostasis

(2010) Yael Pewzner-Jung et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Lipid metabolism in myelinating glial cells: lessons from human inherited disorders and mouse models

(2010) Roman Chrast et al.   JOURNAL OF LIPID RESEARCH

Alexander Disease Mutant Glial Fibrillary Acidic Protein Compromises Glutamate Transport in Astrocytes

(2010) Rujin Tian et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Leukoencephalopathy With Vanishing White Matter: A Review

(2010) Marianna Bugiani et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Permeability of the Paranodal Junction of Myelinated Nerve Fibers

(2010) A. Mierzwa et al.   JOURNAL OF NEUROSCIENCE

Elevated Phosphatidylinositol 3,4,5-Trisphosphate in Glia Triggers Cell-Autonomous Membrane Wrapping and Myelination

(2010) S. Goebbels et al.   JOURNAL OF NEUROSCIENCE

Excitability and Synaptic Communication within the Oligodendrocyte Lineage

(2010) L. M. De Biase et al.   JOURNAL OF NEUROSCIENCE

The changing demographic pattern of multiple sclerosis epidemiology

(2010) Nils Koch-Henriksen et al.   LANCET NEUROLOGY

Highly reactive anti-myelin oligodendrocyte glycoprotein antibodies differentiate demyelinating diseases from viral encephalitis in children

(2010) PH Lalive et al.   Multiple Sclerosis Journal

Neuromyelitis optica: a demyelinating disease characterized by acute destruction and regeneration of perivascular astrocytes

(2010) John DE Parratt et al.   Multiple Sclerosis Journal

Developmental genetics of vertebrate glial–cell specification

(2010) David H. Rowitch et al.   NATURE

Retinoid X receptor gamma signaling accelerates CNS remyelination

(2010) Jeffrey K Huang et al.   NATURE NEUROSCIENCE

Nasu–Hakola disease and primary microglial dysfunction

(2010) Marino M. Bianchin et al.   Nature Reviews Neurology

Visualization of cytoplasmic diffusion within living myelin sheaths of CNS white matter axons using microinjection of the fluorescent dye Lucifer Yellow

(2010) Alexander A. Velumian et al.   NEUROIMAGE

Metachromatic Leukodystrophy – An Update

(2010) V. Gieselmann et al.   NEUROPEDIATRICS

Dlg1-PTEN Interaction Regulates Myelin Thickness to Prevent Damaging Peripheral Nerve Overmyelination

(2010) L. Cotter et al.   SCIENCE

Regulation of Oligodendrocyte Differentiation and Myelination

(2010) B. Emery   SCIENCE

Neuronal loss in Pelizaeus–Merzbacher disease differs in various mutations of the proteolipid protein 1

(2009) Anders A. F. Sima et al.   ACTA NEUROPATHOLOGICA

Astrocytes: biology and pathology

(2009) Michael V. Sofroniew et al.   ACTA NEUROPATHOLOGICA

Neuromyelitis optica: Pathogenicity of patient immunoglobulin in vivo

(2009) Monika Bradl et al.   ANNALS OF NEUROLOGY

Antibodies to native myelin oligodendrocyte glycoprotein in children with inflammatory demyelinating central nervous system disease

(2009) Fabienne Brilot et al.   ANNALS OF NEUROLOGY

Multiple sclerosis: Distribution of inflammatory cells in newly forming lesions

(2009) Andrew P. D. Henderson et al.   ANNALS OF NEUROLOGY

Progressive Multifocal Leukoencephalopathy in Patients on Immunomodulatory Therapies

(2009) Eugene O. Major   Annual Review of Medicine

Diffusely Abnormal White Matter in Chronic Multiple Sclerosis

(2009) Alexandra Seewann et al.   ARCHIVES OF NEUROLOGY

Neuromyelitis optica: Passive transfer to rats by human immunoglobulin

(2009) Makoto Kinoshita et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Greater loss of axons in primary progressive multiple sclerosis plaques compared to secondary progressive disease

(2009) E. C. Tallantyre et al.   BRAIN

Mitochondrial changes within axons in multiple sclerosis

(2009) D. J. Mahad et al.   BRAIN

The relation between inflammation and neurodegeneration in multiple sclerosis brains

(2009) Josa M. Frischer et al.   BRAIN

Two novel gap junction protein alpha 12 gene mutations in two Chinese patients with Pelizaeus–Merzbacher-like disease

(2009) Jingmin Wang et al.   BRAIN & DEVELOPMENT

On the biogenesis of myelin membranes: Sorting, trafficking and cell polarity

(2009) Wia Baron et al.   FEBS LETTERS

Dysregulation of the Wnt pathway inhibits timely myelination and remyelination in the mammalian CNS

(2009) S. P.J. Fancy et al.   GENES & DEVELOPMENT

Early ultrastructural defects of axons and axon-glia junctions in mice lacking expression ofCnp1

(2009) Julia M. Edgar et al.   GLIA

Adult Ceramide Synthase 2 (CERS2)-deficient Mice Exhibit Myelin Sheath Defects, Cerebellar Degeneration, and Hepatocarcinomas

(2009) Silke Imgrund et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Integrin-mediated axoglial interactions initiate myelination in the central nervous system

(2009) Joana Câmara et al.   JOURNAL OF CELL BIOLOGY

Potential Mechanisms of the Human Polyomavirus JC in Neural Oncogenesis

(2009) Luis Del Valle et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

An Integrin-Contactin Complex Regulates CNS Myelination by Differential Fyn Phosphorylation

(2009) L. S. Laursen et al.   JOURNAL OF NEUROSCIENCE

Phosphatidylinositol 4,5-Bisphosphate-Dependent Interaction of Myelin Basic Protein with the Plasma Membrane in Oligodendroglial Cells and Its Rapid Perturbation by Elevated Calcium

(2009) S. Nawaz et al.   JOURNAL OF NEUROSCIENCE

Activation of the Mammalian Target of Rapamycin (mTOR) Is Essential for Oligodendrocyte Differentiation

(2009) W. A. Tyler et al.   JOURNAL OF NEUROSCIENCE

Akt Signals through the Mammalian Target of Rapamycin Pathway to Regulate CNS Myelination

(2009) S. P. Narayanan et al.   JOURNAL OF NEUROSCIENCE

Myelin-associated glycoprotein and its axonal receptors

(2009) Ronald L. Schnaar et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Disposition of axonal caspr with respect to glial cell membranes: Implications for the process of myelination

(2009) Liliana Pedraza et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Multiple functions of the paranodal junction of myelinated nerve fibers

(2009) Jack Rosenbluth   JOURNAL OF NEUROSCIENCE RESEARCH

Spatiotemporal ablation of myelinating glia-specificneurofascin(NfascNF155) in mice reveals gradual loss of paranodal axoglial junctions and concomitant disorganization of axonal domains

(2009) Anilkumar M. Pillai et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Virtual hypoxia and chronic necrosis of demyelinated axons in multiple sclerosis

(2009) Bruce D Trapp et al.   LANCET NEUROLOGY

Kif1b is essential for mRNA localization in oligodendrocytes and development of myelinated axons

(2009) David A Lyons et al.   NATURE GENETICS

Endoplasmic reticulum stress in disorders of myelinating cells

(2009) Wensheng Lin et al.   NATURE NEUROSCIENCE

Remyelination capacity of the MS brain decreases with disease chronicity

(2009) T. Goldschmidt et al.   NEUROLOGY

Neuromyelitis optica with intraspinal expansion of Schwann cell remyelination

(2009) Hayato Ikota et al.   NEUROPATHOLOGY

Molecular disruptions of the panglial syncytium block potassium siphoning and axonal saltatory conduction: pertinence to neuromyelitis optica and other demyelinating diseases of the central nervous system

(2009) J.E. Rash   NEUROSCIENCE

What Is the Optimal Value of the g-Ratio for Myelinated Fibers in the Rat CNS? A Theoretical Approach

(2009) Taylor Chomiak et al.   PLoS One

Metachromatic leukodystrophy: genetics, pathogenesis and therapeutic options

(2008) Volkmar Gieselmann   ACTA PAEDIATRICA

Gray matter atrophy in multiple sclerosis: A longitudinal study

(2008) Elizabeth Fisher et al.   ANNALS OF NEUROLOGY

Homogeneity of active demyelinating lesions in established multiple sclerosis

(2008) Esther C. W. Breij et al.   ANNALS OF NEUROLOGY

Multiple Sclerosis: An Immune or Neurodegenerative Disorder?

(2008) Bruce D. Trapp et al.   Annual Review of Neuroscience

Myelin Basic Protein as a “PI(4,5)P2-Modulin”: A New Biological Function for a Major Central Nervous System Protein†

(2008) Abdiwahab A. Musse et al.   BIOCHEMISTRY

Clinical and radiographic spectrum of pathologically confirmed tumefactive multiple sclerosis

(2008) C. F. Lucchinetti et al.   BRAIN

Differentiation block of oligodendroglial progenitor cells as a cause for remyelination failure in chronic multiple sclerosis

(2008) T. Kuhlmann et al.   BRAIN

Substantial Archaeocortical Atrophy and Neuronal Loss in Multiple Sclerosis

(2008) Dimitrios Papadopoulos et al.   BRAIN PATHOLOGY

Properties of astrocytes cultured from GFAP over-expressing and GFAP mutant mice

(2008) Woosung Cho et al.   EXPERIMENTAL CELL RESEARCH

Autophagy induced by Alexander disease-mutant GFAP accumulation is regulated by p38/MAPK and mTOR signaling pathways

(2008) G. Tang et al.   HUMAN MOLECULAR GENETICS

Glial and neuronal isoforms of Neurofascin have distinct roles in the assembly of nodes of Ranvier in the central nervous system

(2008) Barbara Zonta et al.   JOURNAL OF CELL BIOLOGY

Tight junctions potentiate the insulative properties of small CNS myelinated axons

(2008) Jerome Devaux et al.   JOURNAL OF CELL BIOLOGY

Activation of oligodendroglial Fyn kinase enhances translation of mRNAs transported in hnRNP A2–dependent RNA granules

(2008) Robin White et al.   JOURNAL OF CELL BIOLOGY

Aquaporin-4–binding autoantibodies in patients with neuromyelitis optica impair glutamate transport by down-regulating EAAT2

(2008) Shannon R. Hinson et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Gap Junctions Couple Astrocytes and Oligodendrocytes

(2008) Jennifer L. Orthmann-Murphy et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Multiple Molecular Interactions Determine the Clustering of Caspr2 and Kv1 Channels in Myelinated Axons

(2008) I. Horresh et al.   JOURNAL OF NEUROSCIENCE

Constitutively Active Akt Induces Enhanced Myelination in the CNS

(2008) A. I. Flores et al.   JOURNAL OF NEUROSCIENCE

Postsynaptic Density-93 Clusters Kv1 Channels at Axon Initial Segments Independently of Caspr2

(2008) Y. Ogawa et al.   JOURNAL OF NEUROSCIENCE

The Role and Metabolism of Sulfatide in the Nervous System

(2008) Matthias Eckhardt   MOLECULAR NEUROBIOLOGY

Developmental Regulation of TREM2 and DAP12 Expression in the Murine CNS: Implications for Nasu-Hakola Disease

(2008) J. Cameron Thrash et al.   NEUROCHEMICAL RESEARCH

Neuregulin-1/ErbB Signaling Serves Distinct Functions in Myelination of the Peripheral and Central Nervous System

(2008) Bastian G. Brinkmann et al.   NEURON

Ceramide Triggers Budding of Exosome Vesicles into Multivesicular Endosomes

(2008) K. Trajkovic et al.   SCIENCE

White matter in learning, cognition and psychiatric disorders

(2008) R. Douglas Fields   TRENDS IN NEUROSCIENCES

Cx29 and Cx32, two connexins expressed by myelinating glia, do not interact and are functionally distinct

(2007) Meejin Ahn et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Cortical demyelination in PML and MS: Similarities and differences

(2007) N. M. Moll et al.   NEUROLOGY