Neuroprotective intervention by interferon-γ blockade prevents CD8+T cell–mediated dendrite and synapse loss

Differential expression of interferon-γ and chemokine genes distinguishes Rasmussen encephalitis from cortical dysplasia and provides evidence for an early Th1 immune response

(2013) Geoffrey C Owens et al.   Journal of Neuroinflammation

Cutting Edge: Neuronal Recognition by CD8 T Cells Elicits Central Diabetes Insipidus

(2012) T. Scheikl et al.   JOURNAL OF IMMUNOLOGY

Late motor decline after accomplished remyelination: Impact for progressive multiple sclerosis

(2011) Natalia Manrique-Hoyos et al.   ANNALS OF NEUROLOGY

A reversible form of axon damage in experimental autoimmune encephalomyelitis and multiple sclerosis

(2011) Ivana Nikić et al.   NATURE MEDICINE

Neurons are MHC Class I-Dependent Targets for CD8 T Cells upon Neurotropic Viral Infection

(2011) Grégoire Chevalier et al.   PLoS Pathogens

Rapid Formation of Extended Processes and Engagement of Theiler's Virus-Infected Neurons by CNS-Infiltrating CD8 T Cells

(2010) Jeremiah R. McDole et al.   AMERICAN JOURNAL OF PATHOLOGY

Mitochondrial DNA deletions and neurodegeneration in multiple sclerosis

(2010) Graham R. Campbell et al.   ANNALS OF NEUROLOGY

T cells can mediate viral clearance from ependyma but not from brain parenchyma in a major histocompatibility class I- and perforin-independent manner

(2010) Daniel D. Pinschewer et al.   BRAIN

Innate and adaptive immune control of genetically engineered live-attenuated arenavirus vaccine prototypes

(2010) Daniel D. Pinschewer et al.   INTERNATIONAL IMMUNOLOGY

CD8+ T Cells Cause Disability and Axon Loss in a Mouse Model of Multiple Sclerosis

(2010) Chandra Deb et al.   PLoS One

Collateral Bystander Damage by Myelin-Directed CD8+ T Cells Causes Axonal Loss

(2009) Bettina Sobottka et al.   AMERICAN JOURNAL OF PATHOLOGY

CD8+ T-cell clones dominate brain infiltrates in Rasmussen encephalitis and persist in the periphery

(2009) Nicholas Schwab et al.   BRAIN

Mitochondrial changes within axons in multiple sclerosis

(2009) D. J. Mahad et al.   BRAIN

Fontolizumab in moderate to severe Crohnʼs disease: A phase 2, randomized, double-blind, placebo-controlled, multiple-dose study

(2009) Walter Reinisch et al.   INFLAMMATORY BOWEL DISEASES

Demyelinated Axons and Motor Function Are Protected by Genetic Deletion of Perforin in a Mouse Model of Multiple Sclerosis

(2009) Chandra Deb et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Cytotoxic CD8+ T Cell-Neuron Interactions: Perforin-Dependent Electrical Silencing Precedes But Is Not Causally Linked to Neuronal Cell Death

(2009) S. G. Meuth et al.   JOURNAL OF NEUROSCIENCE

Generation of recombinant lymphocytic choriomeningitis viruses with trisegmented genomes stably expressing two additional genes of interest

(2009) S. F. Emonet et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Interferon-γ directly induces neurotoxicity through a neuron specific, calcium-permeable complex of IFN-γ receptor and AMPA GluR1 receptor

(2008) Tetsuya Mizuno et al.   FASEB JOURNAL

Regional variations in the extent and pattern of grey matter demyelination in multiple sclerosis: a comparison between the cerebral cortex, cerebellar cortex, deep grey matter nuclei and the spinal cord

(2008) C P Gilmore et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Paraneoplastic syndromes of the CNS

(2008) Josep Dalmau et al.   LANCET NEUROLOGY