Accumulation of 8,9-unsaturated sterols drives oligodendrocyte formation and remyelination

Induction of myelinating oligodendrocytes in human cortical spheroids

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Transcription elongation factors represent in vivo cancer dependencies in glioblastoma

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The Effect of Small Molecules on Sterol Homeostasis: Measuring 7-Dehydrocholesterol in Dhcr7-Deficient Neuro2a Cells and Human Fibroblasts

(2016) Zeljka Korade et al.   JOURNAL OF MEDICINAL CHEMISTRY

Identification of the Kappa-Opioid Receptor as a Therapeutic Target for Oligodendrocyte Remyelination

(2016) Feng Mei et al.   JOURNAL OF NEUROSCIENCE

Selective targeting of mutant adenomatous polyposis coli (APC) in colorectal cancer

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CNS Myelin Sheath Lengths Are an Intrinsic Property of Oligodendrocytes

(2015) Marie E. Bechler et al.   CURRENT BIOLOGY

Drug-based modulation of endogenous stem cells promotes functional remyelination in vivo

(2015) Fadi J. Najm et al.   NATURE

Silicon Incorporated Morpholine Antifungals: Design, Synthesis, and Biological Evaluation

(2015) Gorakhnath R. Jachak et al.   ACS Medicinal Chemistry Letters

NR2F1 Mutations Cause Optic Atrophy with Intellectual Disability

(2014) Daniëlle G.M. Bosch et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Analysis and Experimental Inhibition of Distal Cholesterol Biosynthesis

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Micropillar arrays as a high-throughput screening platform for therapeutics in multiple sclerosis

(2014) Feng Mei et al.   NATURE MEDICINE

A regenerative approach to the treatment of multiple sclerosis

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Azole Affinity of Sterol 14α-Demethylase (CYP51) Enzymes from Candida albicans and Homo sapiens

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Atypical antipsychotics alter cholesterol and fatty acid metabolism in vitro

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Therapy of Pelizaeus-Merzbacher disease in mice by feeding a cholesterol-enriched diet

(2012) Gesine Saher et al.   NATURE MEDICINE

A culture system to study oligodendrocyte myelination processes using engineered nanofibers

(2012) Seonok Lee et al.   NATURE METHODS

Glial Progenitor Cell-Based Treatment and Modeling of Neurological Disease

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Rapid and robust generation of functional oligodendrocyte progenitor cells from epiblast stem cells

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Overcoming remyelination failure in multiple sclerosis and other myelin disorders

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Retinoid X receptor gamma signaling accelerates CNS remyelination

(2010) Jeffrey K Huang et al.   NATURE NEUROSCIENCE

Statin Therapy Inhibits Remyelination in the Central Nervous System

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Promotion of central nervous system remyelination by induced differentiation of oligodendrocyte precursor cells

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Highly sensitive quantification of key regulatory oxysterols in biological samples by LC-ESI-MS/MS

(2008) Akira Honda et al.   JOURNAL OF LIPID RESEARCH

Negative Impact of Statins on Oligodendrocytes and Myelin Formation In Vitro and In Vivo

(2008) S. Klopfleisch et al.   JOURNAL OF NEUROSCIENCE

A Novel Nuclear Signaling Pathway for Thromboxane A2 Receptors in Oligodendrocytes: Evidence for Signaling Compartmentalization during Differentiation

(2008) F. Mir et al.   MOLECULAR AND CELLULAR BIOLOGY

Remyelination in the CNS: from biology to therapy

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Lathosterol side chain amides—A new class of human lathosterol oxidase inhibitors

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