Human antibodies against the myelin oligodendrocyte glycoprotein can cause complement-dependent demyelination

Influence of type I IFN signaling on anti-MOG antibody-mediated demyelination

(2017) Carsten Tue Berg et al.   Journal of Neuroinflammation

Myelin-specific multiple sclerosis antibodies cause complement-dependent oligodendrocyte loss and demyelination

(2017) Yiting Liu et al.   Acta Neuropathologica Communications

Peripheral VH4+ plasmablasts demonstrate autoreactive B cell expansion toward brain antigens in early multiple sclerosis patients

(2016) Jacqueline R. Rivas et al.   ACTA NEUROPATHOLOGICA

Myelin-reactive antibodies initiate T cell-mediated CNS autoimmune disease by opsonization of endogenous antigen

(2016) Silke Kinzel et al.   ACTA NEUROPATHOLOGICA

MOG-IgG in NMO and related disorders: a multicenter study of 50 patients. Part 1: Frequency, syndrome specificity, influence of disease activity, long-term course, association with AQP4-IgG, and origin

(2016) Sven Jarius et al.   Journal of Neuroinflammation

Clinical spectrum associated with MOG autoimmunity in adults: significance of sharing rodent MOG epitopes

(2016) Maria Sepúlveda et al.   JOURNAL OF NEUROLOGY

Multicentre comparison of a diagnostic assay: aquaporin-4 antibodies in neuromyelitis optica

(2016) Patrick Waters et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Screening for MOG-IgG and 27 other anti-glial and anti-neuronal autoantibodies in ‘pattern II multiple sclerosis’ and brain biopsy findings in a MOG-IgG-positive case

(2016) Sven Jarius et al.   Multiple Sclerosis Journal

Autoantibody-boosted T-cell reactivation in the target organ triggers manifestation of autoimmune CNS disease

(2016) Anne-Christine Flach et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Screening for MOG-IgG and 27 other anti-glial and anti-neuronal autoantibodies in ‘pattern II multiple sclerosis’ and brain biopsy findings in a MOG-IgG-positive case

(2016) Sven Jarius et al.   Multiple Sclerosis Journal

Antibodies produced by clonally expanded plasma cells in multiple sclerosis cerebrospinal fluid cause demyelination of spinal cord explants

(2015) Kevin Blauth et al.   ACTA NEUROPATHOLOGICA

Neuromyelitis optica spectrum disorders: comparison of clinical and magnetic resonance imaging characteristics of AQP4-IgG versus MOG-IgG seropositive cases in the Netherlands

(2015) E. D. van Pelt et al.   EUROPEAN JOURNAL OF NEUROLOGY

Anti-MOG antibodies are present in a subgroup of patients with a neuromyelitis optica phenotype

(2015) Anne-Katrin Pröbstel et al.   Journal of Neuroinflammation

Clinical and MRI phenotype of children with MOG antibodies

(2015) Cristina Fernandez-Carbonell et al.   Multiple Sclerosis Journal

Anti-MOG antibodies plead against MS diagnosis in an Acquired Demyelinating Syndromes cohort

(2015) Immy A Ketelslegers et al.   Multiple Sclerosis Journal

International consensus diagnostic criteria for neuromyelitis optica spectrum disorders

(2015) Dean M. Wingerchuk et al.   NEUROLOGY

Clinical and MRI phenotype of children with MOG antibodies

(2015) Cristina Fernandez-Carbonell et al.   Multiple Sclerosis Journal

Anti-MOG antibodies plead against MS diagnosis in an Acquired Demyelinating Syndromes cohort

(2015) Immy A Ketelslegers et al.   Multiple Sclerosis Journal

Overlapping demyelinating syndromes and anti-N-methyl-D-aspartate receptor encephalitis

(2014) Maarten J. Titulaer et al.   ANNALS OF NEUROLOGY

Inhibitor(s) of the classical complement pathway in mouse serum limit the utility of mice as experimental models of neuromyelitis optica

(2014) Julien Ratelade et al.   MOLECULAR IMMUNOLOGY

Neuromyelitis optica MOG-IgG causes reversible lesions in mouse brain

(2014) Samira Saadoun et al.   Acta Neuropathologica Communications

Distinction and Temporal Stability of Conformational Epitopes on Myelin Oligodendrocyte Glycoprotein Recognized by Patients with Different Inflammatory Central Nervous System Diseases

(2013) M. C. Mayer et al.   JOURNAL OF IMMUNOLOGY

International Pediatric Multiple Sclerosis Study Group criteria for pediatric multiple sclerosis and immune-mediated central nervous system demyelinating disorders: revisions to the 2007 definitions

(2013) Lauren B Krupp et al.   Multiple Sclerosis Journal

An Optimized Immunohistochemistry Technique Improves NMO-IgG Detection: Study Comparison with Cell-Based Assays

(2013) Romana Höftberger et al.   PLoS One

T cell-activation in neuromyelitis optica lesions plays a role in their formation

(2013) Maria Pohl et al.   Acta Neuropathologica Communications

Persisting myelin oligodendrocyte glycoprotein antibodies in aquaporin-4 antibody negative pediatric neuromyelitis optica

(2012) K Rostásy et al.   Multiple Sclerosis Journal

Myelin-oligodendrocyte glycoprotein antibodies in adults with a neuromyelitis optica phenotype

(2012) J. Kitley et al.   NEUROLOGY

Diagnostic criteria for multiple sclerosis: 2010 Revisions to the McDonald criteria

(2011) Chris H. Polman et al.   ANNALS OF NEUROLOGY

S1P1 receptor subtype inhibits demyelination and regulates chemokine release in cerebellar slice cultures

(2011) Graham K. Sheridan et al.   GLIA

Complement activating antibodies to myelin oligodendrocyte glycoprotein in neuromyelitis optica and related disorders

(2011) Simone Mader et al.   Journal of Neuroinflammation

Antibodies to MOG are transient in childhood acute disseminated encephalomyelitis

(2011) A. K. Probstel et al.   NEUROLOGY

Temporal dynamics of anti-MOG antibodies in CNS demyelinating diseases

(2010) Franziska Di Pauli et al.   CLINICAL IMMUNOLOGY

Highly reactive anti-myelin oligodendrocyte glycoprotein antibodies differentiate demyelinating diseases from viral encephalitis in children

(2010) PH Lalive et al.   Multiple Sclerosis Journal

Antibody responses to EBV and native MOG in pediatric inflammatory demyelinating CNS diseases

(2010) R. C. Selter et al.   NEUROLOGY

Neuromyelitis optica: Pathogenicity of patient immunoglobulin in vivo

(2009) Monika Bradl et al.   ANNALS OF NEUROLOGY

Antibodies to native myelin oligodendrocyte glycoprotein in children with inflammatory demyelinating central nervous system disease

(2009) Fabienne Brilot et al.   ANNALS OF NEUROLOGY

Live imaging of remyelination after antibody-mediated demyelination in an ex-vivo model for immune mediated CNS damage

(2009) Melanie D. Harrer et al.   EXPERIMENTAL NEUROLOGY

Spontaneous relapsing-remitting EAE in the SJL/J mouse: MOG-reactive transgenic T cells recruit endogenous MOG-specific B cells

(2009) Bernadette Pöllinger et al.   JOURNAL OF EXPERIMENTAL MEDICINE