A unified cell biological perspective on axon–myelin injury

The node of Ranvier in CNS pathology

(2014) I. Lorena Arancibia-Carcamo et al.   ACTA NEUROPATHOLOGICA

Microglia Development and Function

(2014) Debasis Nayak et al.   Annual Review of Immunology

Myelin Membrane Wrapping of CNS Axons by PI(3,4,5)P3-Dependent Polarized Growth at the Inner Tongue

(2014) Nicolas Snaidero et al.   CELL

Label-free in vivo imaging of myelinated axons in health and disease with spectral confocal reflectance microscopy

(2014) Aaron J Schain et al.   NATURE MEDICINE

Distinct Profiles of Myelin Distribution Along Single Axons of Pyramidal Neurons in the Neocortex

(2014) G. S. Tomassy et al.   SCIENCE

Microglial nodules in early multiple sclerosis white matter are associated with degenerating axons

(2013) Shailender Singh et al.   ACTA NEUROPATHOLOGICA

Iron and neurodegeneration in the multiple sclerosis brain

(2013) Simon Hametner et al.   ANNALS OF NEUROLOGY

Identification of Long-Lived Proteins Reveals Exceptional Stability of Essential Cellular Structures

(2013) Brandon H. Toyama et al.   CELL

Developmental pruning of early-stage myelin segments during CNS myelination in vivo

(2013) Peng Liu et al.   CELL RESEARCH

Forebrain Engraftment by Human Glial Progenitor Cells Enhances Synaptic Plasticity and Learning in Adult Mice

(2013) Xiaoning Han et al.   Cell Stem Cell

Individual Oligodendrocytes Have Only a Few Hours in which to Generate New Myelin Sheaths In Vivo

(2013) Tim Czopka et al.   DEVELOPMENTAL CELL

Membrane domain organization of myelinated axons requires βII spectrin

(2013) Chuansheng Zhang et al.   JOURNAL OF CELL BIOLOGY

The Sphingolipid Psychosine Inhibits Fast Axonal Transport in Krabbe Disease by Activation of GSK3  and Deregulation of Molecular Motors

(2013) L. Cantuti Castelvetri et al.   JOURNAL OF NEUROSCIENCE

Sodium and Potassium Currents Influence Wallerian Degeneration of Injured Drosophila Axons

(2013) B. Mishra et al.   JOURNAL OF NEUROSCIENCE

Axonal Guillain-Barré syndrome: concepts and controversies

(2013) Satoshi Kuwabara et al.   LANCET NEUROLOGY

M2 microglia and macrophages drive oligodendrocyte differentiation during CNS remyelination

(2013) Veronique E Miron et al.   NATURE NEUROSCIENCE

Oligodendrocyte progenitors balance growth with self-repulsion to achieve homeostasis in the adult brain

(2013) Ethan G Hughes et al.   NATURE NEUROSCIENCE

Cellular, subcellular and functional in vivo labeling of the spinal cord using vital dyes

(2013) Elisa Romanelli et al.   Nature Protocols

Aberrant Schwann Cell Lipid Metabolism Linked to Mitochondrial Deficits Leads to Axon Degeneration and Neuropathy

(2013) Andreu Viader et al.   NEURON

Three Mechanisms Assemble Central Nervous System Nodes of Ranvier

(2013) Keiichiro Susuki et al.   NEURON

Demyelination in Mild Cognitive Impairment Suggests Progression Path to Alzheimer’s Disease

(2013) Cristian Carmeli et al.   PLoS One

The Phr1 Ubiquitin Ligase Promotes Injury-Induced Axon Self-Destruction

(2013) Elisabetta Babetto et al.   Cell Reports

Myelin Membrane Assembly Is Driven by a Phase Transition of Myelin Basic Proteins Into a Cohesive Protein Meshwork

(2013) Shweta Aggarwal et al.   PLOS BIOLOGY

Neurotransmitter-Triggered Transfer of Exosomes Mediates Oligodendrocyte–Neuron Communication

(2013) Carsten Frühbeis et al.   PLOS BIOLOGY

Cell polarity in myelinating glia: From membrane flow to diffusion barriers

(2012) Mikael Simons et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Axon degeneration: Molecular mechanisms of a self-destruction pathway

(2012) Jack T. Wang et al.   JOURNAL OF CELL BIOLOGY

Targeted Ablation of Oligodendrocytes Induces Axonal Pathology Independent of Overt Demyelination

(2012) L.-J. Oluich et al.   JOURNAL OF NEUROSCIENCE

Oligodendroglia metabolically support axons and contribute to neurodegeneration

(2012) Youngjin Lee et al.   NATURE

Glycolytic oligodendrocytes maintain myelin and long-term axonal integrity

(2012) Ursula Fünfschilling et al.   NATURE

Primary oligodendrocyte death does not elicit anti-CNS immunity

(2012) Giuseppe Locatelli et al.   NATURE NEUROSCIENCE

Progressive multiple sclerosis: pathology and pathogenesis

(2012) Hans Lassmann et al.   Nature Reviews Neurology

Quantitative imaging of energy expenditure in human brain

(2012) Xiao-Hong Zhu et al.   NEUROIMAGE

A Central Role for the ERK-Signaling Pathway in Controlling Schwann Cell Plasticity and Peripheral Nerve Regeneration In Vivo

(2012) Ilaria Napoli et al.   NEURON

dSarm/Sarm1 Is Required for Activation of an Injury-Induced Axon Death Pathway

(2012) J. M. Osterloh et al.   SCIENCE

The Highwire Ubiquitin Ligase Promotes Axonal Degeneration by Tuning Levels of Nmnat Protein

(2012) Xin Xiong et al.   PLOS BIOLOGY

Actin Polymerization Is Essential for Myelin Sheath Fragmentation during Wallerian Degeneration

(2011) J. Jung et al.   JOURNAL OF NEUROSCIENCE

Genetically Induced Adult Oligodendrocyte Cell Death Is Associated with Poor Myelin Clearance, Reduced Remyelination, and Axonal Damage

(2011) H. B. F. Pohl et al.   JOURNAL OF NEUROSCIENCE

Rapid Disruption of Axon-Glial Integrity in Response to Mild Cerebral Hypoperfusion

(2011) M. M. Reimer et al.   JOURNAL OF NEUROSCIENCE

ZNRF1 promotes Wallerian degeneration by degrading AKT to induce GSK3B-dependent CRMP2 phosphorylation

(2011) Shuji Wakatsuki et al.   NATURE CELL BIOLOGY

A reversible form of axon damage in experimental autoimmune encephalomyelitis and multiple sclerosis

(2011) Ivana Nikić et al.   NATURE MEDICINE

Antibodies to MOG are transient in childhood acute disseminated encephalomyelitis

(2011) A. K. Probstel et al.   NEUROLOGY

Targeted Ablation of Oligodendrocytes Triggers Axonal Damage

(2011) Aniket Ghosh et al.   PLoS One

Neurite outgrowth inhibitor Nogo-A establishes spatial segregation and extent of oligodendrocyte myelination

(2011) S. Y. C. Chong et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Central nervous system myelin: structure, synthesis and assembly

(2011) Shweta Aggarwal et al.   TRENDS IN CELL BIOLOGY

Wallerian Degeneration, WldS, and Nmnat

(2010) Michael P. Coleman et al.   Annual Review of Neuroscience

A genetic mouse model of adult-onset, pervasive central nervous system demyelination with robust remyelination

(2010) Maria Traka et al.   BRAIN

Axonal Loss and Neurofilament Phosphorylation Changes Accompany Lesion Development and Clinical Progression in Multiple Sclerosis

(2010) Lucas Schirmer et al.   BRAIN PATHOLOGY

Wallerian degeneration of zebrafish trigeminal axons in the skin is required for regeneration and developmental pruning

(2010) S. M. Martin et al.   DEVELOPMENT

Myelination and the trophic support of long axons

(2010) Klaus-Armin Nave   NATURE REVIEWS NEUROSCIENCE

A Glial Signal Consisting of Gliomedin and NrCAM Clusters Axonal Na+ Channels during the Formation of Nodes of Ranvier

(2010) Konstantin Feinberg et al.   NEURON

Molecular Motors in Neurons: Transport Mechanisms and Roles in Brain Function, Development, and Disease

(2010) Nobutaka Hirokawa et al.   NEURON

Endogenous Nmnat2 Is an Essential Survival Factor for Maintenance of Healthy Axons

(2010) Jonathan Gilley et al.   PLOS BIOLOGY

Early ultrastructural defects of axons and axon-glia junctions in mice lacking expression ofCnp1

(2009) Julia M. Edgar et al.   GLIA

Phosphatidylinositol 4,5-Bisphosphate-Dependent Interaction of Myelin Basic Protein with the Plasma Membrane in Oligodendroglial Cells and Its Rapid Perturbation by Elevated Calcium

(2009) S. Nawaz et al.   JOURNAL OF NEUROSCIENCE

Virtual hypoxia and chronic necrosis of demyelinated axons in multiple sclerosis

(2009) Bruce D Trapp et al.   LANCET NEUROLOGY

A dual leucine kinase–dependent axon self-destruction program promotes Wallerian degeneration

(2009) Bradley R Miller et al.   NATURE NEUROSCIENCE

Alzheimer's disease as homeostatic responses to age-related myelin breakdown

(2009) George Bartzokis   NEUROBIOLOGY OF AGING

Contactin-2/TAG-1-directed autoimmunity is identified in multiple sclerosis patients and mediates gray matter pathology in animals

(2009) T. Derfuss et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Synchronous Hyperactivity and Intercellular Calcium Waves in Astrocytes in Alzheimer Mice

(2009) K. V. Kuchibhotla et al.   SCIENCE

Myelin Basic Protein as a “PI(4,5)P2-Modulin”: A New Biological Function for a Major Central Nervous System Protein†

(2008) Abdiwahab A. Musse et al.   BIOCHEMISTRY

Molecular domains of myelinated axons in the peripheral nervous system

(2008) James L. Salzer et al.   GLIA