Rapid and efficient generation of oligodendrocytes from human induced pluripotent stem cells using transcription factors

Astrocyte pathology in a human neural stem cell model of frontotemporal dementia caused by mutant TAU protein

(2017) Anna-Lena Hallmann et al.   Scientific Reports

Non-steroidal anti-inflammatory drug indometacin enhances endogenous remyelination

(2015) Anna Preisner et al.   ACTA NEUROPATHOLOGICA

Human Embryonic Stem Cell-Derived Oligodendrocyte Progenitors Remyelinate the Brain and Rescue Behavioral Deficits following Radiation

(2015) Jinghua Piao et al.   Cell Stem Cell

CNS Myelin Sheath Lengths Are an Intrinsic Property of Oligodendrocytes

(2015) Marie E. Bechler et al.   CURRENT BIOLOGY

Oct4‐induced oligodendrocyte progenitor cells enhance functional recovery in spinal cord injury model

(2015) Jeong Beom Kim et al.   EMBO JOURNAL

Downregulation of the microtubule associated protein Tau impairs process outgrowth and myelin basic protein mRNA transport in oligodendrocytes

(2015) Veronika Seiberlich et al.   GLIA

Skin-derived neural precursors competitively generate functional myelin in adult demyelinated mice

(2015) Sabah Mozafari et al.   JOURNAL OF CLINICAL INVESTIGATION

Drug-based modulation of endogenous stem cells promotes functional remyelination in vivo

(2015) Fadi J. Najm et al.   NATURE

Invited review: Frontotemporal dementia caused bymicrotubule-associated protein taugene (MAPT) mutations: a chameleon for neuropathology and neuroimaging

(2015) Bernardino Ghetti et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Modulation of the Innate Immune Response by Human Neural Precursors Prevails over Oligodendrocyte Progenitor Remyelination to Rescue a Severe Model of Pelizaeus-Merzbacher Disease

(2015) Antoine Marteyn et al.   STEM CELLS

Distinct Neurodegenerative Changes in an Induced Pluripotent Stem Cell Model of Frontotemporal Dementia Linked to Mutant TAU Protein

(2015) Marc Ehrlich et al.   Stem Cell Reports

Micropillar arrays as a high-throughput screening platform for therapeutics in multiple sclerosis

(2014) Feng Mei et al.   NATURE MEDICINE

Transcription factor induction of human oligodendrocyte progenitor fate and differentiation

(2014) J. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Efficient Generation of Myelinating Oligodendrocytes from Primary Progressive Multiple Sclerosis Patients by Induced Pluripotent Stem Cells

(2014) Panagiotis Douvaras et al.   Stem Cell Reports

Amyotrophic lateral sclerosis: Problems and prospects

(2013) Jemeen Sreedharan et al.   ANNALS OF NEUROLOGY

Human iPSC-Derived Oligodendrocyte Progenitor Cells Can Myelinate and Rescue a Mouse Model of Congenital Hypomyelination

(2013) Su Wang et al.   Cell Stem Cell

Longitudinal white matter changes in frontotemporal dementia subtypes

(2013) Bonnie Y. K. Lam et al.   HUMAN BRAIN MAPPING

A regenerative approach to the treatment of multiple sclerosis

(2013) Vishal A. Deshmukh et al.   NATURE

Generation of oligodendroglial cells by direct lineage conversion

(2013) Nan Yang et al.   NATURE BIOTECHNOLOGY

Transcription factor–mediated reprogramming of fibroblasts to expandable, myelinogenic oligodendrocyte progenitor cells

(2013) Fadi J Najm et al.   NATURE BIOTECHNOLOGY

Derivation and Expansion Using Only Small Molecules of Human Neural Progenitors for Neurodegenerative Disease Modeling

(2013) Peter Reinhardt et al.   PLoS One

High Yields of Oligodendrocyte Lineage Cells from Human Embryonic Stem Cells at Physiological Oxygen Tensions for Evaluation of Translational Biology

(2013) Sybil R.L. Stacpoole et al.   Stem Cell Reports

Programming human pluripotent stem cells into white and brown adipocytes

(2012) Tim Ahfeldt et al.   NATURE CELL BIOLOGY

A culture system to study oligodendrocyte myelination processes using engineered nanofibers

(2012) Seonok Lee et al.   NATURE METHODS

Neuroprotection and repair in multiple sclerosis

(2012) Robin J. M. Franklin et al.   Nature Reviews Neurology

Glial Progenitor Cell-Based Treatment and Modeling of Neurological Disease

(2012) S. A. Goldman et al.   SCIENCE

Human neural progenitors from different foetal forebrain regions remyelinate the adult mouse spinal cord

(2011) Delphine Buchet et al.   BRAIN

Differentiation of induced pluripotent stem cells into functional oligodendrocytes

(2011) Marcin Czepiel et al.   GLIA

Lentiviral Vector Design and Imaging Approaches to Visualize the Early Stages of Cellular Reprogramming

(2011) Eva Warlich et al.   MOLECULAR THERAPY

Response of Human Oligodendrocyte Progenitors to Growth Factors and Axon Signals

(2010) Qiao Ling Cui et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Clinico-pathological evidence that axonal loss underlies disability in progressive multiple sclerosis

(2010) Emma C Tallantyre et al.   Multiple Sclerosis Journal

Sox10 directs neural stem cells toward the oligodendrocyte lineage by decreasing Suppressor of Fused expression

(2010) C. D. Pozniak et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Directing human neural stem/precursor cells into oligodendrocytes by overexpression of Olig2 transcription factor

(2009) Cécile L. Maire et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Differentiation of human oligodendrocytes from pluripotent stem cells

(2009) Bao-Yang Hu et al.   Nature Protocols

Ascl1 is required for oligodendrocyte development in the spinal cord

(2008) M. Sugimori et al.   DEVELOPMENT

White Matter Tauopathy With Globular Glial Inclusions: A Distinct Sporadic Frontotemporal Lobar Degeneration

(2008) Gabor G. Kovacs et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Directed differentiation of hippocampal stem/progenitor cells in the adult brain

(2008) Sebastian Jessberger et al.   NATURE NEUROSCIENCE

Induced Pluripotent Stem Cell Generation Using a Single Lentiviral Stem Cell Cassette

(2008) Cesar A. Sommer et al.   STEM CELLS