Cerebrovascular disease in ageing and Alzheimer’s disease

Post-mortem assessment of hypoperfusion of cerebral cortex in Alzheimer’s disease and vascular dementia

(2015) Taya Thomas et al.   BRAIN

Cortical superficial siderosis: detection and clinical significance in cerebral amyloid angiopathy and related conditions

(2015) Andreas Charidimou et al.   BRAIN

Pathophysiology of Hypoperfusion of the Precuneus in Early Alzheimer's Disease

(2015) J. Scott Miners et al.   BRAIN PATHOLOGY

Amyloid β peptide-induced inhibition of endothelial nitric oxide production involves oxidative stress-mediated constitutive eNOS/HSP90 interaction and disruption of agonist-mediated Akt activation

(2015) Folami Lamoke et al.   Journal of Neuroinflammation

Lack of Widespread BBB Disruption in Alzheimer’s Disease Models: Focus on Therapeutic Antibodies

(2015) Nga Bien-Ly et al.   NEURON

Apolipoprotein E-dependent load of white matter hyperintensities in Alzheimer’s disease: a voxel-based lesion mapping study

(2015) Katrin Morgen et al.   Alzheimers Research & Therapy

Lacunar Infarction and Small Vessel Disease: Pathology and Pathophysiology

(2015) Louis R Caplan   Journal of Stroke

Cardiovascular risk factors and future risk of Alzheimer’s disease

(2014) Renée FAG de Bruijn et al.   BMC Medicine

The overlap between vascular disease and Alzheimer’s disease - lessons from pathology

(2014) Johannes Attems et al.   BMC Medicine

Pathophysiology of white matter perfusion in Alzheimer’s disease and vascular dementia

(2014) Rachel Barker et al.   BRAIN

White Matter Hypoperfusion and Damage in Dementia: Post-Mortem Assessment

(2014) Seth Love et al.   BRAIN PATHOLOGY

Impaired Cerebral Autoregulation and Vasomotor Reactivity in Sporadic Alzheimer’s Disease

(2014) Aisha Abeelen et al.   Current Alzheimer Research

Age-Dependent Neurovascular Dysfunction and Damage in a Mouse Model of Cerebral Amyloid Angiopathy

(2014) Laibaik Park et al.   STROKE

CSF and Plasma Amyloid-β Temporal Profiles and Relationships with Neurological Status and Mortality after Severe Traumatic Brain Injury

(2014) Stefania Mondello et al.   Scientific Reports

Associations Between Cerebral Small-Vessel Disease and Alzheimer Disease Pathology as Measured by Cerebrospinal Fluid Biomarkers

(2014) Maartje I. Kester et al.   JAMA Neurology

Arterial Stiffness and β-Amyloid Progression in Nondemented Elderly Adults

(2014) Timothy M. Hughes et al.   JAMA Neurology

Regional differences in the morphological and functional effects of aging on cerebral basement membranes and perivascular drainage of amyloid-β from the mouse brain

(2013) Cheryl A. Hawkes et al.   AGING CELL

The Neuropathology of Vascular Disease in the Medical Research Council Cognitive Function and Ageing Study (MRC CFAS)

(2013) Kathryn Richardson et al.   Current Alzheimer Research

Current status of renin–aldosterone angiotensin system-targeting anti-hypertensive drugs as therapeutic options for Alzheimer's disease

(2013) Emma Louise Ashby et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

Endothelin-converting Enzymes Degrade Intracellular β-Amyloid Produced within the Endosomal/Lysosomal Pathway and Autophagosomes

(2013) Javier Pacheco-Quinto et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Assessing White Matter Ischemic Damage in Dementia Patients by Measurement of Myelin Proteins

(2013) Rachel Barker et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Efficacy of the Specific Endothelin A Receptor Antagonist Zibotentan (ZD4054) in Colorectal Cancer: A Preclinical Study

(2013) S.-u. Haque et al.   MOLECULAR CANCER THERAPEUTICS

Cardiovascular disease contributes to Alzheimer's disease: evidence from large-scale genome-wide association studies

(2013) Guiyou Liu et al.   NEUROBIOLOGY OF AGING

Neurovascular decoupling is associated with severity of cerebral amyloid angiopathy

(2013) S. Peca et al.   NEUROLOGY

APOE genotype and MRI markers of cerebrovascular disease: Systematic review and meta-analysis

(2013) S. Schilling et al.   NEUROLOGY

Patterns of cerebral amyloid angiopathy define histopathological phenotypes in Alzheimer's disease

(2013) N. Allen et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Regional variability of imaging biomarkers in autosomal dominant Alzheimer's disease

(2013) T. L. S. Benzinger et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Functional magnetic resonance imaging detection of vascular reactivity in cerebral amyloid angiopathy

(2012) Andrew Dumas et al.   ANNALS OF NEUROLOGY

Cerebrovascular atherosclerosis correlates with Alzheimer pathology in neurodegenerative dementias

(2012) M. Yarchoan et al.   BRAIN

Deficiency in Mural Vascular Cells Coincides with Blood-Brain Barrier Disruption in Alzheimer's Disease

(2012) Jesse D. Sengillo et al.   BRAIN PATHOLOGY

A 1-42-RAGE Interaction Disrupts Tight Junctions of the Blood-Brain Barrier Via Ca2+-Calcineurin Signaling

(2012) S.-Y. Kook et al.   JOURNAL OF NEUROSCIENCE

The vascular factor in Alzheimer's disease: A study in Golgi technique and electron microscopy

(2012) Stavros J. Baloyannis et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Morphological and Pathological Evolution of the Brain Microcirculation in Aging and Alzheimer’s Disease

(2012) Jesse M. Hunter et al.   PLoS One

Disruption of Arterial Perivascular Drainage of Amyloid-β from the Brains of Mice Expressing the Human APOE ε4 Allele

(2012) Cheryl A. Hawkes et al.   PLoS One

Cerebral Blood Flow Measured with 3D Pseudocontinuous Arterial Spin-labeling MR Imaging in Alzheimer Disease and Mild Cognitive Impairment: A Marker for Disease Severity

(2012) Maja A. A. Binnewijzend et al.   RADIOLOGY

Perivascular drainage of solutes is impaired in the ageing mouse brain and in the presence of cerebral amyloid angiopathy

(2011) Cheryl A. Hawkes et al.   ACTA NEUROPATHOLOGICA

Amyloid Beta Induces Oxidative Stress-Mediated Blood–Brain Barrier Changes in Capillary Amyloid Angiopathy

(2011) Anna Carrano et al.   ANTIOXIDANTS & REDOX SIGNALING

Atrial Fibrillation and Risk of Dementia: A Prospective Cohort Study

(2011) Sascha Dublin et al.   JOURNAL OF THE AMERICAN GERIATRICS SOCIETY

Vascular risk factors promote conversion from mild cognitive impairment to Alzheimer disease

(2011) J. Li et al.   NEUROLOGY

Hypoxia Due to Cardiac Arrest Induces a Time-Dependent Increase in Serum Amyloid β Levels in Humans

(2011) Henrik Zetterberg et al.   PLoS One

Cerebral Small Vessel Disease and Risk of Death, Ischemic Stroke, and Cardiac Complications in Patients With Atherosclerotic Disease

(2011) Mandy M.A. Conijn et al.   STROKE

Amyloid-β Contributes to Blood–Brain Barrier Leakage in Transgenic Human Amyloid Precursor Protein Mice and in Humans With Cerebral Amyloid Angiopathy

(2011) Anika M.S. Hartz et al.   STROKE

ASL Perfusion MRI Predicts Cognitive Decline and Conversion From MCI to Dementia

(2010) Linda L. Chao et al.   ALZHEIMER DISEASE & ASSOCIATED DISORDERS

Hypometabolism in Alzheimer-Affected Brain Regions in Cognitively Healthy Latino Individuals Carrying the Apolipoprotein E ε4 Allele

(2010) Jessica B. S. Langbaum et al.   ARCHIVES OF NEUROLOGY

Pericytes regulate the blood–brain barrier

(2010) Annika Armulik et al.   NATURE

Assessment of activation of the plasma kallikrein-kinin system in frontal and temporal cortex in Alzheimer's disease and vascular dementia

(2010) Emma L. Ashby et al.   NEUROBIOLOGY OF AGING

Prevalence of superficial siderosis in patients with cerebral amyloid angiopathy

(2010) J. Linn et al.   NEUROLOGY

Pericytes Control Key Neurovascular Functions and Neuronal Phenotype in the Adult Brain and during Brain Aging

(2010) Robert D. Bell et al.   NEURON

Endothelin receptor antagonists: Potential in Alzheimer's disease

(2010) Jennifer Palmer et al.   PHARMACOLOGICAL RESEARCH

Endothelin-Converting Enzyme-2 Is Increased in Alzheimer’s Disease and Up-Regulated by Aβ

(2009) Jennifer C. Palmer et al.   AMERICAN JOURNAL OF PATHOLOGY

Contribution of Vascular Risk Factors to the Progression in Alzheimer Disease

(2009) Elizabeth P. Helzner et al.   ARCHIVES OF NEUROLOGY

High Prevalence of Orthostatic Hypotension in Mild Dementia

(2009) Hogne Sonnesyn et al.   DEMENTIA AND GERIATRIC COGNITIVE DISORDERS

Insights into the pathogenesis and pathogenicity of cerebral amyloid angiopathy

(2009) Seth Love   Frontiers in Bioscience-Landmark

Hypoperfusion and Ischemia in Cerebral Amyloid Angiopathy Documented by 99mTc-ECD Brain Perfusion SPECT

(2009) Y.-A. Chung et al.   JOURNAL OF NUCLEAR MEDICINE

Upregulation of BACE1 and β-Amyloid Protein Mediated by Chronic Cerebral Hypoperfusion Contributes to Cognitive Impairment and Pathogenesis of Alzheimer’s Disease

(2009) Cai Zhiyou et al.   NEUROCHEMICAL RESEARCH

Mild Cognitive Impairment and Alzheimer Disease: Patterns of Altered Cerebral Blood Flow at MR Imaging

(2009) Weiying Dai et al.   RADIOLOGY

Angiotensins in Alzheimer's disease – friend or foe?

(2009) Patrick G. Kehoe et al.   TRENDS IN NEUROSCIENCES

Effects of HNE-modification induced by Aβ on neprilysin expression and activity in SH-SY5Y cells

(2008) Rui Wang et al.   JOURNAL OF NEUROCHEMISTRY

The up-regulation of BACE1 mediated by hypoxia and ischemic injury: role of oxidative stress and HIF1α

(2008) Michela Guglielmotto et al.   JOURNAL OF NEUROCHEMISTRY

Contribution of vascular pathology to the clinical expression of dementia

(2008) Dorothea Strozyk et al.   NEUROBIOLOGY OF AGING

Hypoxia increases Aβ generation by altering β- and γ-cleavage of APP

(2007) Liang Li et al.   NEUROBIOLOGY OF AGING

Angiotensin-converting enzyme (ACE) levels and activity in Alzheimer's disease, and relationship of perivascular ACE-1 to cerebral amyloid angiopathy

(2007) J. S. Miners et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY