Advanced MRI and staging of multiple sclerosis lesions

Custom fit 3D-printed brain holders for comparison of histology with MRI in marmosets

(2016) Joseph R. Guy et al.   JOURNAL OF NEUROSCIENCE METHODS

MRI criteria for the diagnosis of multiple sclerosis: MAGNIMS consensus guidelines

(2016) Massimo Filippi et al.   LANCET NEUROLOGY

Clinical and pathological insights into the dynamic nature of the white matter multiple sclerosis plaque

(2015) Josa M. Frischer et al.   ANNALS OF NEUROLOGY

A gradient in cortical pathology in multiple sclerosis by in vivo quantitative 7 T imaging

(2015) Caterina Mainero et al.   BRAIN

Veins in plaques of multiple sclerosis patients – a longitudinal magnetic resonance imaging study at 7 Tesla –

(2015) Assunta Dal-Bianco et al.   EUROPEAN RADIOLOGY

Activation Status of Human Microglia Is Dependent on Lesion Formation Stage and Remyelination in Multiple Sclerosis

(2015) Laura A.N. Peferoen et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Multiple sclerosis lesion formation and early evolution revisited: A weekly high-resolution magnetic resonance imaging study

(2015) Charles RG Guttmann et al.   Multiple Sclerosis Journal

Sample-size calculations for short-term proof-of-concept studies of tissue protection and repair in multiple sclerosis lesions via conventional clinical imaging

(2015) Daniel S Reich et al.   Multiple Sclerosis Journal

Exploring the origins of grey matter damage in multiple sclerosis

(2015) Massimiliano Calabrese et al.   NATURE REVIEWS NEUROSCIENCE

Focal disturbances in the blood–brain barrier are associated with formation of neuroinflammatory lesions

(2015) Jorge Ivan Alvarez et al.   NEUROBIOLOGY OF DISEASE

Gadolinium-based MRI characterization of leptomeningeal inflammation in multiple sclerosis

(2015) Martina Absinta et al.   NEUROLOGY

Blood coagulation protein fibrinogen promotes autoimmunity and demyelination via chemokine release and antigen presentation

(2015) Jae Kyu Ryu et al.   Nature Communications

Multiple sclerosis lesion formation and early evolution revisited: A weekly high-resolution magnetic resonance imaging study

(2015) Charles RG Guttmann et al.   Multiple Sclerosis Journal

Sample-size calculations for short-term proof-of-concept studies of tissue protection and repair in multiple sclerosis lesions via conventional clinical imaging

(2015) Daniel S Reich et al.   Multiple Sclerosis Journal

Pathologic heterogeneity persists in early active multiple sclerosis lesions

(2014) Imke Metz et al.   ANNALS OF NEUROLOGY

The formation of inflammatory demyelinated lesions in cerebral white matter

(2014) Pietro Maggi et al.   ANNALS OF NEUROLOGY

Increased Meningeal T and Plasma Cell Infiltration is Associated with Early Subpial Cortical Demyelination in Common Marmosets with Experimental Autoimmune Encephalomyelitis

(2014) Nadine Kramann et al.   BRAIN PATHOLOGY

The translational biology of remyelination: Past, present, and future

(2014) Robin J. M. Franklin et al.   GLIA

Differential roles of microglia and monocytes in the inflamed central nervous system

(2014) Ryo Yamasaki et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Detailing intra-lesional venous lumen shrinking in multiple sclerosis investigated by sFLAIR MRI at 7-T

(2014) Katharina Müller et al.   JOURNAL OF NEUROLOGY

MRI-based myelin water imaging: A technical review

(2014) Eva Alonso-Ortiz et al.   MAGNETIC RESONANCE IN MEDICINE

Iron in multiple sclerosis: roles in neurodegeneration and repair

(2014) Erin Stephenson et al.   Nature Reviews Neurology

Microglial nodules in early multiple sclerosis white matter are associated with degenerating axons

(2013) Shailender Singh et al.   ACTA NEUROPATHOLOGICA

Seven-tesla phase imaging of acute multiple sclerosis lesions: A new window into the inflammatory process

(2013) Martina Absinta et al.   ANNALS OF NEUROLOGY

Iron and neurodegeneration in the multiple sclerosis brain

(2013) Simon Hametner et al.   ANNALS OF NEUROLOGY

Extracellular matrix metalloproteinase inducer shows active perivascular cuffs in multiple sclerosis

(2013) Smriti M. Agrawal et al.   BRAIN

Disease-specific molecular events in cortical multiple sclerosis lesions

(2013) Marie Therese Fischer et al.   BRAIN

The “central vein sign”: is there a place for susceptibility weighted imaging in possible multiple sclerosis?

(2013) Thomas Kau et al.   EUROPEAN RADIOLOGY

Improved differentiation between MS and vascular brain lesions using FLAIR* at 7 Tesla

(2013) Iris D. Kilsdonk et al.   EUROPEAN RADIOLOGY

Perivenular brain lesions in a primate multiple sclerosis model at 7-tesla magnetic resonance imaging

(2013) María I Gaitán et al.   Multiple Sclerosis Journal

Development, maintenance and disruption of the blood-brain barrier

(2013) Birgit Obermeier et al.   NATURE MEDICINE

Identification of a unique TGF-β–dependent molecular and functional signature in microglia

(2013) Oleg Butovsky et al.   NATURE NEUROSCIENCE

M2 microglia and macrophages drive oligodendrocyte differentiation during CNS remyelination

(2013) Veronique E Miron et al.   NATURE NEUROSCIENCE

Micro-compartment specific T2⁎ relaxation in the brain

(2013) Pascal Sati et al.   NEUROIMAGE

Magnetic resonance frequency shifts during acute MS lesion formation

(2013) V. Wiggermann et al.   NEUROLOGY

Contribution of cortical lesion subtypes at 7T MRI to physical and cognitive performance in MS

(2013) A. S. Nielsen et al.   NEUROLOGY

Iron Is a Sensitive Biomarker for Inflammation in Multiple Sclerosis Lesions

(2013) Veela Mehta et al.   PLoS One

Quantitative Susceptibility Mapping of Multiple Sclerosis Lesions at Various Ages

(2013) Weiwei Chen et al.   RADIOLOGY

Improved detection of focal cortical lesions using 7T magnetisation transfer imaging in patients with multiple sclerosis

(2013) R. Abdel-Fahim et al.   Multiple Sclerosis and Related Disorders

Observations on the brain vasculature in multiple sclerosis: A historical perspective

(2013) Alex D. Rae-Grant et al.   Multiple Sclerosis and Related Disorders

Tertiary lymphoid organ development coincides with determinant spreading of the myelin-specific T cell response

(2012) Stefanie Kuerten et al.   ACTA NEUROPATHOLOGICA

Reduced Diffusion in a Subset of Acute MS Lesions: A Serial Multiparametric MRI Study

(2012) P. Eisele et al.   AMERICAN JOURNAL OF NEURORADIOLOGY

Oligodendrocytes and the early multiple sclerosis lesion

(2012) John W. Prineas et al.   ANNALS OF NEUROLOGY

Cortical remyelination: A new target for repair therapies in multiple sclerosis

(2012) Ansi Chang et al.   ANNALS OF NEUROLOGY

Cortical lesion load associates with progression of disability in multiple sclerosis

(2012) M. Calabrese et al.   BRAIN

Meningeal inflammation plays a role in the pathology of primary progressive multiple sclerosis

(2012) Sung R. Choi et al.   BRAIN

Iron deposition in multiple sclerosis lesions measured by susceptibility-weighted imaging filtered phase: A case control study

(2012) Jesper Hagemeier et al.   JOURNAL OF MAGNETIC RESONANCE IMAGING

Improved detection of cortical MS lesions with phase-sensitive inversion recovery MRI

(2012) Varun Sethi et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

B-Cell Enrichment and Epstein-Barr Virus Infection in Inflammatory Cortical Lesions in Secondary Progressive Multiple Sclerosis

(2012) Roberta Magliozzi et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Association between pathological and MRI findings in multiple sclerosis

(2012) Massimo Filippi et al.   LANCET NEUROLOGY

Initial investigation of the blood-brain barrier in MS lesions at 7 tesla

(2012) María I Gaitán et al.   Multiple Sclerosis Journal

A serial in vivo 7T magnetic resonance phase imaging study of white matter lesions in multiple sclerosis

(2012) Wei Bian et al.   Multiple Sclerosis Journal

Lesion morphology at 7 Tesla MRI differentiates Susac syndrome from multiple sclerosis

(2012) Jens Wuerfel et al.   Multiple Sclerosis Journal

Progressive multiple sclerosis: pathology and pathogenesis

(2012) Hans Lassmann et al.   Nature Reviews Neurology

Multiple sclerosis shrinks intralesional, and enlarges extralesional, brain parenchymal veins

(2012) M. I. Gaitan et al.   NEUROLOGY

Heterogeneity of cortical lesions in multiple sclerosis: Clinical and pathologic implications

(2012) E.-J. Kooi et al.   NEUROLOGY

Postmortem verification of MS cortical lesion detection with 3D DIR

(2012) A. Seewann et al.   NEUROLOGY

Biophysical mechanisms of MRI signal frequency contrast in multiple sclerosis

(2012) D. A. Yablonskiy et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Assessment of Disease Activity in Multiple Sclerosis Phenotypes with Combined Gadolinium- and Superparamagnetic Iron Oxide–enhanced MR Imaging

(2012) Thomas Tourdias et al.   RADIOLOGY

FLAIR*: A Combined MR Contrast Technique for Visualizing White Matter Lesions and Parenchymal Veins

(2012) Pascal Sati et al.   RADIOLOGY

CNS sterile injury: just another wound healing?

(2012) Ravid Shechter et al.   TRENDS IN MOLECULAR MEDICINE

Fibrinogen-induced perivascular microglial clustering is required for the development of axonal damage in neuroinflammation

(2012) Dimitrios Davalos et al.   Nature Communications

Evolution of the blood-brain barrier in newly forming multiple sclerosis lesions

(2011) María I. Gaitán et al.   ANNALS OF NEUROLOGY

Diagnostic criteria for multiple sclerosis: 2010 Revisions to the McDonald criteria

(2011) Chris H. Polman et al.   ANNALS OF NEUROLOGY

Tracking iron in multiple sclerosis: a combined imaging and histopathological study at 7 Tesla

(2011) F. Bagnato et al.   BRAIN

Meningeal inflammation is widespread and linked to cortical pathology in multiple sclerosis

(2011) Owain W. Howell et al.   BRAIN

A reversible form of axon damage in experimental autoimmune encephalomyelitis and multiple sclerosis

(2011) Ivana Nikić et al.   NATURE MEDICINE

A case of multiple sclerosis presenting with inflammatory cortical demyelination

(2011) B. F. G. Popescu et al.   NEUROLOGY

Ultra-high-field imaging distinguishes MS lesions from asymptomatic white matter lesions

(2011) E. C. Tallantyre et al.   NEUROLOGY

Review: The architecture of inflammatory demyelinating lesions: implications for studies on pathogenesis

(2011) H. Lassmann   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Inflammatory Cortical Demyelination in Early Multiple Sclerosis

(2011) Claudia F. Lucchinetti et al.   NEW ENGLAND JOURNAL OF MEDICINE

Chronic Multiple Sclerosis Lesions: Characterization with High-Field-Strength MR Imaging

(2011) Bing Yao et al.   RADIOLOGY

A Gradient of neuronal loss and meningeal inflammation in multiple sclerosis

(2010) Roberta Magliozzi et al.   ANNALS OF NEUROLOGY

Imaging Cortical Lesions in Multiple Sclerosis With Ultra–High-Field Magnetic Resonance Imaging

(2010) David Pitt et al.   ARCHIVES OF NEUROLOGY

Demyelination versus remyelination in progressive multiple sclerosis

(2010) Stephan Bramow et al.   BRAIN

High field (9.4 Tesla) magnetic resonance imaging of cortical grey matter lesions in multiple sclerosis

(2010) Klaus Schmierer et al.   BRAIN

Focal and diffuse cortical degenerative changes in a marmoset model of multiple sclerosis

(2010) IM Pomeroy et al.   Multiple Sclerosis Journal

Presence of a central vein within white matter lesions on susceptibility weighted imaging: a specific finding for multiple sclerosis?

(2010) Nina Lummel et al.   NEURORADIOLOGY

Multiple sclerosis: Distribution of inflammatory cells in newly forming lesions

(2009) Andrew P. D. Henderson et al.   ANNALS OF NEUROLOGY

Cortical Lesions and Atrophy Associated With Cognitive Impairment in Relapsing-Remitting Multiple Sclerosis

(2009) Massimiliano Calabrese et al.   ARCHIVES OF NEUROLOGY

Accumulation of cortical lesions in MS: relation with cognitive impairment

(2009) SD Roosendaal et al.   Multiple Sclerosis Journal

Effector T cell interactions with meningeal vascular structures in nascent autoimmune CNS lesions

(2009) Ingo Bartholomäus et al.   NATURE

Cortical lesions in primary progressive multiple sclerosis: A 2-year longitudinal MR study

(2009) M. Calabrese et al.   NEUROLOGY

Remyelination capacity of the MS brain decreases with disease chronicity

(2009) T. Goldschmidt et al.   NEUROLOGY

In vivo imaging of cortical pathology in multiple sclerosis using ultra-high field MRI

(2009) C. Mainero et al.   NEUROLOGY

Magnetization transfer ratio evolution with demyelination and remyelination in multiple sclerosis lesions

(2008) Jacqueline T. Chen et al.   ANNALS OF NEUROLOGY

Quantitative in vivo magnetic resonance imaging of multiple sclerosis at 7 Tesla with sensitivity to iron

(2008) Kathryn E. Hammond et al.   ANNALS OF NEUROLOGY

Pluriformity of inflammation in multiple sclerosis shown by ultra-small iron oxide particle enhancement

(2008) Machteld M. Vellinga et al.   BRAIN

Differentiation block of oligodendroglial progenitor cells as a cause for remyelination failure in chronic multiple sclerosis

(2008) T. Kuhlmann et al.   BRAIN

Visualisation of the kinetics of macrophage infiltration during experimental autoimmune encephalomyelitis by magnetic resonance imaging

(2008) Kurt Baeten et al.   JOURNAL OF NEUROIMMUNOLOGY

Autoimmunity Against Myelin Oligodendrocyte Glycoprotein Is Dispensable for the Initiation Although Essential for the Progression of Chronic Encephalomyelitis in Common Marmosets

(2008) S. Anwar Jagessar et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

DEMONSTRATING THE PERIVASCULAR DISTRIBUTION OF MS LESIONS IN VIVO WITH 7-TESLA MRI

(2008) E. C. Tallantyre et al.   NEUROLOGY

Diffuse cortical atrophy in a marmoset model of multiple sclerosis

(2008) Ian M. Pomeroy et al.   NEUROSCIENCE LETTERS