Transplantation and Damage-Associated Molecular Patterns (DAMPs)

Allopurinol preconditioning attenuates renal ischemia/reperfusion injury by inhibiting HMGB1 expression in a rat model

(2016) Jiang-qiao Zhou et al.   Acta Cirurgica Brasileira

Anti–high mobility group box 1 monoclonal antibody improves ischemia/reperfusion injury and mode of liver regeneration after partial hepatectomy

(2016) Masahiro Sugihara et al.   AMERICAN JOURNAL OF SURGERY

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

(2016) Daniel J Klionsky et al.   Autophagy

Immune modulation by ER stress and inflammation in the tumor microenvironment

(2016) Jeffrey J. Rodvold et al.   CANCER LETTERS

Ferroptosis: process and function

(2016) Y Xie et al.   CELL DEATH AND DIFFERENTIATION

The role of Toll-like receptor 4 (TLR4) in cardiac ischaemic-reperfusion injury, cardioprotection and preconditioning

(2016) Sam Man Lee et al.   CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY

Filament assemblies in foreign nucleic acid sensors

(2016) Jungsan Sohn et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Endoplasmic reticulum stress of Kupffer cells involved in the conversion of natural regulatory T cells to Th17 cells in liver ischemia-reperfusion injury

(2016) Jialin Gao et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Novel Ferroptosis Inhibitors with Improved Potency and ADME Properties

(2016) Sam Hofmans et al.   JOURNAL OF MEDICINAL CHEMISTRY

Improving the outcome of kidney transplantation by ameliorating renal ischemia reperfusion injury: lost in translation?

(2016) T. C. Saat et al.   Journal of Translational Medicine

Natural killer cells play a critical role in mediating inflammation and graft failure during antibody-mediated rejection of kidney allografts

(2016) Naoki Kohei et al.   KIDNEY INTERNATIONAL

Role of autophagy in the bimodal stage after spinal cord ischemia reperfusion injury in rats

(2016) Bo Fang et al.   NEUROSCIENCE

Danger in the Intensive Care Unit

(2016) Kim Timmermans et al.   SHOCK

Autophagy and the Kidney: Implications for Ischemia-Reperfusion Injury and Therapy

(2015) Jean-Paul Decuypere et al.   AMERICAN JOURNAL OF KIDNEY DISEASES

Blood Vessels in Allotransplantation

(2015) P. Abrahimi et al.   AMERICAN JOURNAL OF TRANSPLANTATION

The Roles of Mitochondrial Damage-Associated Molecular Patterns in Diseases

(2015) Kiichi Nakahira et al.   ANTIOXIDANTS & REDOX SIGNALING

Membrane-bound heat shock proteins facilitate the uptake of dying cells and cross-presentation of cellular antigen

(2015) Haiyan Zhu et al.   APOPTOSIS

Purinergic signaling in the immune system

(2015) Francesco Di Virgilio et al.   AUTONOMIC NEUROSCIENCE-BASIC & CLINICAL

Hyaluronan-induced VEGF-C promotes fibrosis-induced lymphangiogenesis via Toll-like receptor 4-dependent signal pathway

(2015) Yu Jin Jung et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Necroptosis signalling is tuned by phosphorylation of MLKL residues outside the pseudokinase domain activation loop

(2015) M. C. Tanzer et al.   BIOCHEMICAL JOURNAL

NZ28-induced inhibition of HSF1, SP1 and NF-κB triggers the loss of the natural killer cell-activating ligands MICA/B on human tumor cells

(2015) Daniela Schilling et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Oxidized extracellular DNA as a stress signal that may modify response to anticancer therapy

(2015) Kristina Glebova et al.   CANCER LETTERS

Gasdermin D is an executor of pyroptosis and required for interleukin-1β secretion

(2015) Wan-ting He et al.   CELL RESEARCH

Molecular mechanisms regulating NLRP3 inflammasome activation

(2015) Eun-Kyeong Jo et al.   Cellular & Molecular Immunology

ROS and Autophagy: Interactions and Molecular Regulatory Mechanisms

(2015) Lulu Li et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

ER Stress and Autophagy

(2015) W. Lee et al.   CURRENT MOLECULAR MEDICINE

Innate immunity for better or worse govern the allograft response

(2015) Leo E. Otterbein et al.   Current Opinion in Organ Transplantation

Protein disulfide isomerase and Nox: new partners in redox signaling

(2015) Silvia Trevelin et al.   CURRENT PHARMACEUTICAL DESIGN

PMA and crystal-induced neutrophil extracellular trap formation involves RIPK1-RIPK3-MLKL signaling

(2015) Jyaysi Desai et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

AIM2 inflammasome in infection, cancer, and autoimmunity: Role in DNA sensing, inflammation, and innate immunity

(2015) Si Ming Man et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Endoplasmic reticulum stress and Nrf2 signaling in cardiovascular diseases

(2015) Luciano Cominacini et al.   FREE RADICAL BIOLOGY AND MEDICINE

Oxidation-specific epitopes are major targets of innate immunity in atherothrombosis

(2015) B. Bartolini Gritti et al.   Hamostaseologie

Endoplasmic Reticulum Stress Activates the Inflammasome via NLRP3- and Caspase-2-Driven Mitochondrial Damage

(2015) Denise N. Bronner et al.   IMMUNITY

DNA Damage Primes the Type I Interferon System via the Cytosolic DNA Sensor STING to Promote Anti-Microbial Innate Immunity

(2015) Anetta Härtlova et al.   IMMUNITY

Genetics, genomics, and evolutionary biology of NKG2D ligands

(2015) Raphael Carapito et al.   IMMUNOLOGICAL REVIEWS

The nucleic acid-sensing inflammasomes

(2015) Tsan Sam Xiao   IMMUNOLOGICAL REVIEWS

Regulation of inflammasome activation

(2015) Si Ming Man et al.   IMMUNOLOGICAL REVIEWS

Initiation and perpetuation of NLRP3 inflammasome activation and assembly

(2015) Eric I. Elliott et al.   IMMUNOLOGICAL REVIEWS

Bright expression of CD91 identifies highly activated human dendritic cells that can be expanded by defensins

(2015) Monica Cappelletti et al.   IMMUNOLOGY

The Effect of Autophagy on Inflammation Cytokines in Renal Ischemia/Reperfusion Injury

(2015) Haibin Ling et al.   INFLAMMATION

Autophagy in DNA Damage Response

(2015) Piotr Czarny et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Protein Folding and Mechanisms of Proteostasis

(2015) José Díaz-Villanueva et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Autophagy as a Stress Response Pathway in the Immune System

(2015) Abhisek Bhattacharya et al.   INTERNATIONAL REVIEWS OF IMMUNOLOGY

Nucleic Acid–Sensing Receptors: Rheostats of Autoimmunity and Autoinflammation

(2015) Shruti Sharma et al.   JOURNAL OF IMMUNOLOGY

Endoplasmic Reticulum Stress of Neutrophils Is Required for Ischemia/Reperfusion–Induced Acute Lung Injury

(2015) Rong Hu et al.   JOURNAL OF IMMUNOLOGY

Positive Feedback Regulation of Type I IFN Production by the IFN-Inducible DNA Sensor cGAS

(2015) Feng Ma et al.   JOURNAL OF IMMUNOLOGY

Role of the NLRP3 inflammasome in the transient release of IL-1β induced by monosodium urate crystals in human fibroblast-like synoviocytes

(2015) Shu-cong Zheng et al.   Journal of Inflammation-London

The mitochondrial permeability transition: A current perspective on its identity and role in ischaemia/reperfusion injury

(2015) Andrew P. Halestrap et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Inflammatory genes in rat livers from cardiac- and brain death donors

(2015) Tanja C. Saat et al.   JOURNAL OF SURGICAL RESEARCH

Transplantation of donor hearts after circulatory or brain death in a rat model

(2015) Shiliang Li et al.   JOURNAL OF SURGICAL RESEARCH

Necroinflammation in Kidney Disease

(2015) S. R. Mulay et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Lack of hyaluronidases exacerbates renal post-ischemic injury, inflammation, and fibrosis

(2015) Vanessa Colombaro et al.   KIDNEY INTERNATIONAL

Necroptosis and parthanatos are involved in remote lung injury after receiving ischemic renal allografts in rats

(2015) Hailin Zhao et al.   KIDNEY INTERNATIONAL

Necroptotic Cell Death Signaling and Execution Pathway: Lessons from Knockout Mice

(2015) José Belizário et al.   MEDIATORS OF INFLAMMATION

Apoptosis, autophagy, necroptosis, and cancer metastasis

(2015) Zhenyi Su et al.   Molecular Cancer

Glycoprotein Quality Control and Endoplasmic Reticulum Stress

(2015) Qian Wang et al.   MOLECULES

Caspase-11 cleaves gasdermin D for non-canonical inflammasome signalling

(2015) Nobuhiko Kayagaki et al.   NATURE

Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death

(2015) Jianjin Shi et al.   NATURE

Necroptosis and its role in inflammation

(2015) Manolis Pasparakis et al.   NATURE

Proteostasis control by the unfolded protein response

(2015) Claudio Hetz et al.   NATURE CELL BIOLOGY

The diverse role of RIP kinases in necroptosis and inflammation

(2015) John Silke et al.   NATURE IMMUNOLOGY

Exploiting replicative stress to treat cancer

(2015) Matthias Dobbelstein et al.   NATURE REVIEWS DRUG DISCOVERY

Hyperthermic intraperitoneal chemotherapy leads to an anticancer immune response via exposure of cell surface heat shock protein 90

(2015) B Zunino et al.   ONCOGENE

Mitochondrial Damage-Associated Molecular Patterns (MTDs) Are Released during Hepatic Ischemia Reperfusion and Induce Inflammatory Responses

(2015) Qianni Hu et al.   PLoS One

Serum Uric Acid and Renal Transplantation Outcomes: At Least 3-Year Post-transplant Retrospective Multivariate Analysis

(2015) Kun Zhang et al.   PLoS One

Cell stress increases ATP release in NLRP3 inflammasome-mediated autoinflammatory diseases, resulting in cytokine imbalance

(2015) Sonia Carta et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A sequence-specific DNA binding small molecule triggers the release of immunogenic signals and phagocytosis in a model of B-cell lymphoma

(2015) JeenJoo S. Kang et al.   QUARTERLY REVIEWS OF BIOPHYSICS

The PERKs of damage-associated molecular patterns mediating cancer immunogenicity: From sensor to the plasma membrane and beyond

(2015) A.R. van Vliet et al.   SEMINARS IN CANCER BIOLOGY

The molecular relationships between apoptosis, autophagy and necroptosis

(2015) Najoua Lalaoui et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

RIP1-Dependent Programmed Necrosis is Negatively Regulated by Caspases During Hepatic Ischemia-Reperfusion

(2015) Dirk Rosentreter et al.   SHOCK

ENDOPLASMIC RETICULUM STRESS IN SEPSIS

(2015) Mohammad Moshahid Khan et al.   SHOCK

C/EBP Homologous Protein-Mediated Endoplasmic Reticulum Stress-Related Renal Apoptosis Is Involved in Rats With Brain Death

(2015) S. Cao et al.   TRANSPLANTATION PROCEEDINGS

Mechanisms of inflammasome activation: recent advances and novel insights

(2015) Sivapriya K. Vanaja et al.   TRENDS IN CELL BIOLOGY

RIPK1 and RIPK3: critical regulators of inflammation and cell death

(2015) Kim Newton   TRENDS IN CELL BIOLOGY

Potential therapeutic targets in the process of nucleic acid recognition: opportunities and challenges

(2015) Shaoheng He et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Multifaceted roles of HSF1 in cancer

(2015) Sufang Jiang et al.   TUMOR BIOLOGY

Intermedin protects against renal ischemia-reperfusion injury by inhibiting endoplasmic reticulum stress

(2015) Yanhong Wang et al.   BMC Nephrology

K+ regulates Ca2+ to drive inflammasome signaling: dynamic visualization of ion flux in live cells

(2015) J R Yaron et al.   Cell Death & Disease

RIPK3 promotes cell death and NLRP3 inflammasome activation in the absence of MLKL

(2015) Kate E. Lawlor et al.   Nature Communications

MicroRNAs in apoptosis, autophagy and necroptosis

(2015) Zhenyi Su et al.   Oncotarget

The TLR4 Agonist Fibronectin Extra Domain A is Cryptic, Exposed by Elastase-2; use in a fibrin matrix cancer vaccine

(2015) Ziad Julier et al.   Scientific Reports

The diverging roles of dendritic cells in kidney allotransplantation

(2015) Manuel Alfredo Podestà et al.   Transplantation Reviews

NKG2D and DNAM-1 Ligands: Molecular Targets for NK Cell-Mediated Immunotherapeutic Intervention in Multiple Myeloma

(2015) Cinzia Fionda et al.   Biomed Research International

NKG2D Receptor and Its Ligands in Host Defense

(2015) L. L. Lanier   Cancer Immunology Research

Oxidative stress-mediated HMGB1 biology

(2015) Yan Yu et al.   Frontiers in Physiology

Molecular and Translational Classifications of DAMPs in Immunogenic Cell Death

(2015) Abhishek D. Garg et al.   Frontiers in Immunology

DAMPs from Cell Death to New Life

(2015) Emilie Vénéreau et al.   Frontiers in Immunology

Irradiation of necrotic cancer cells, employed for pulsing dendritic cells (DCs), potentiates DC vaccine-induced antitumor immunity against high-grade glioma

(2015) Lien Vandenberk et al.   OncoImmunology

Reperfusion injury and reactive oxygen species: The evolution of a concept

(2015) D. Neil Granger et al.   Redox Biology

Mechanisms of Translocation of ER Chaperones to the Cell Surface and Immunomodulatory Roles in Cancer and Autoimmunity

(2015) Valerie R. Wiersma et al.   Frontiers in Oncology

AIM2 Drives Joint Inflammation in a Self-DNA Triggered Model of Chronic Polyarthritis

(2015) Christopher Jakobs et al.   PLoS One

Endoplasmic Reticulum Stress-Induced Autophagy Provides Cytoprotection from Chemical Hypoxia and Oxidant Injury and Ameliorates Renal Ischemia-Reperfusion Injury

(2015) Bhavya B. Chandrika et al.   PLoS One

Impact of Donation Mode on the Proportion and Function of T Lymphocytes in the Liver

(2015) Emmanuel Xystrakis et al.   PLoS One

Gene expression profiles identify both MyD88-independent and MyD88-dependent pathways involved in the maturation of dendritic cells mediated by heparan sulfate: A novel adjuvant

(2015) Meini Wu et al.   Human Vaccines & Immunotherapeutics

Hyaluronan Contributes to Bronchiolitis Obliterans Syndrome and Stimulates Lung Allograft Rejection through Activation of Innate Immunity

(2014) Jamie L. Todd et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Molecular Landscape of T Cell-Mediated Rejection in Human Kidney Transplants: Prominence of CTLA4 and PD Ligands

(2014) J. M. Venner et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Innate Immune Sensing and Signaling of Cytosolic Nucleic Acids

(2014) Jiaxi Wu et al.   Annual Review of Immunology

Endoplasmic Reticulum Stress and Oxidative Stress in Cell Fate Decision and Human Disease

(2014) Stewart Siyan Cao et al.   ANTIOXIDANTS & REDOX SIGNALING

Molecular mechanisms and physiological significance of autophagy during myocardial ischemia and reperfusion

(2014) Yutaka Matsui et al.   Autophagy

TXNIP mediates NLRP3 inflammasome activation in cardiac microvascular endothelial cells as a novel mechanism in myocardial ischemia/reperfusion injury

(2014) Yi Liu et al.   BASIC RESEARCH IN CARDIOLOGY

Nucleocytoplasmic transport under stress conditions and its role in HSP70 chaperone systems

(2014) Shingo Kose et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Pathophysiology of circulating xanthine oxidoreductase: New emerging roles for a multi-tasking enzyme

(2014) Maria Giulia Battelli et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

DNA damage response in renal ischemia–reperfusion and ATP-depletion injury of renal tubular cells

(2014) Zhengwei Ma et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Extracellular nucleotide and nucleoside signaling in vascular and blood disease

(2014) M. Idzko et al.   BLOOD

RAE1 Ligands for the NKG2D Receptor Are Regulated by STING-Dependent DNA Sensor Pathways in Lymphoma

(2014) Adeline R. Lam et al.   CANCER RESEARCH

ER Stress-Induced Clearance of Misfolded GPI-Anchored Proteins via the Secretory Pathway

(2014) Prasanna Satpute-Krishnan et al.   CELL

RIPK1 Regulates RIPK3-MLKL-Driven Systemic Inflammation and Emergency Hematopoiesis

(2014) James A. Rickard et al.   CELL

Essential versus accessory aspects of cell death: recommendations of the NCCD 2015

(2014) L Galluzzi et al.   CELL DEATH AND DIFFERENTIATION

Oncogene-induced reactive oxygen species fuel hyperproliferation and DNA damage response activation

(2014) M Ogrunc et al.   CELL DEATH AND DIFFERENTIATION

What’s the Damage? The Impact of Pathogens on Pathways that Maintain Host Genome Integrity

(2014) Matthew D. Weitzman et al.   Cell Host & Microbe

Functional interplay between ATM/ATR-mediated DNA damage response and DNA repair pathways in oxidative stress

(2014) Shan Yan et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Accumulating evidence for a role of oxidized phospholipids in infectious diseases

(2014) Ulrich Matt et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

DNA Replication and Oncogene-Induced Replicative Stress

(2014) Stephanie A. Hills et al.   CURRENT BIOLOGY

ROS Function in Redox Signaling and Oxidative Stress

(2014) Michael Schieber et al.   CURRENT BIOLOGY

Inflammasome activation in response to dead cells and their metabolites

(2014) Hajime Kono et al.   CURRENT OPINION IN IMMUNOLOGY

Impact of brain death on ischemia/reperfusion injury in liver transplantation

(2014) Tomasz Dziodzio et al.   Current Opinion in Organ Transplantation

S100A1 is released from ischemic cardiomyocytes and signals myocardial damage via Toll-like receptor 4

(2014) D. Rohde et al.   EMBO Molecular Medicine

Mitochondrial damage-associated molecular patterns and vascular function

(2014) C. F. Wenceslau et al.   EUROPEAN HEART JOURNAL

Oxidative stress-dependent activation of the eIF2α–ATFr unfolded protein response branch by skin sensitizer 1-fluoro-2,4-dinitrobenzene modulates dendritic-like cell maturation and inflammatory status in a biphasic manner

(2014) Andreia Luís et al.   FREE RADICAL BIOLOGY AND MEDICINE

STING-Dependent Cytosolic DNA Sensing Mediates Innate Immune Recognition of Immunogenic Tumors

(2014) Seng-Ryong Woo et al.   IMMUNITY

NK cells after transplantation: friend or foe

(2014) Uzi Hadad et al.   IMMUNOLOGIC RESEARCH

Inflammatory triggers of acute rejection of organ allografts

(2014) Daniel N. Mori et al.   IMMUNOLOGICAL REVIEWS

Human Natural Killer Cells: Origin, Receptors, Function, and Clinical Applications

(2014) Lorenzo Moretta et al.   INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY

NKG2D signaling in cancer immunosurveillance

(2014) Alejandro López-Soto et al.   INTERNATIONAL JOURNAL OF CANCER

Regulation of apoptosis by heat shock proteins

(2014) Donna Kennedy et al.   IUBMB LIFE

High-mobility group box-1 in sterile inflammation

(2014) A. Tsung et al.   JOURNAL OF INTERNAL MEDICINE

Circulating microparticles carry oxidation-specific epitopes and are recognized by natural IgM antibodies

(2014) Dimitrios Tsiantoulas et al.   JOURNAL OF LIPID RESEARCH

Regulated Cell Death in AKI

(2014) A. Linkermann et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Biglycan-triggered TLR-2- and TLR-4-signaling exacerbates the pathophysiology of ischemic acute kidney injury

(2014) Kristin Moreth et al.   MATRIX BIOLOGY

Mitochondrial ROS and involvement of Bcl-2 as a mitochondrial ROS regulator

(2014) Stephen Jun Fei Chong et al.   MITOCHONDRION

The alarmin IL-33 promotes regulatory T-cell function in the intestine

(2014) Chris Schiering et al.   NATURE

Nucleotide signalling during inflammation

(2014) Marco Idzko et al.   NATURE

Emerging functions of the unfolded protein response in immunity

(2014) Sophie Janssens et al.   NATURE IMMUNOLOGY

Heat-Shock Proteins and Acute Ischaemic Kidney Injury

(2014) Stephen O'Neill et al.   NEPHRON EXPERIMENTAL NEPHROLOGY

Necroptosis

(2014) Andreas Linkermann et al.   NEW ENGLAND JOURNAL OF MEDICINE

ER stress, autophagy and immunogenic cell death in photodynamic therapy-induced anti-cancer immune responses

(2014) Abhishek D. Garg et al.   PHOTOCHEMICAL & PHOTOBIOLOGICAL SCIENCES

The Alarmin Concept Applied to Human Renal Transplantation: Evidence for a Differential Implication of HMGB1 and IL-33

(2014) Antoine Thierry et al.   PLoS One

Synchronized renal tubular cell death involves ferroptosis

(2014) Andreas Linkermann et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Innate and adaptive immune responses subsequent to ischemia-reperfusion injury in the kidney

(2014) C. Denecke et al.   PROGRES EN UROLOGIE

Atorvastatin Post-Conditioning Attenuates Myocardial Ischemia Reperfusion Injury via Inhibiting Endoplasmic Reticulum Stress–Related Apoptosis

(2014) Jing-gang Xia et al.   SHOCK

No effect of remote ischaemic conditioning on inflammation in a porcine kidney transplantation model

(2014) Niels Secher et al.   TRANSPLANT IMMUNOLOGY

N-acetylcysteine attenuates reactive-oxygen-species-mediated endoplasmic reticulum stress during liver ischemia-reperfusion injury

(2014) Yong Sun   WORLD JOURNAL OF GASTROENTEROLOGY

Tenascin-C: Form versus function

(2014) Sean P Giblin et al.   Cell Adhesion & Migration

Dnase2a Deficiency Uncovers Lysosomal Clearance of Damaged Nuclear DNA via Autophagy

(2014) Yuk Yuen Lan et al.   Cell Reports

Cellular Oxidative Stress Response Controls the Antiviral and Apoptotic Programs in Dengue Virus-Infected Dendritic Cells

(2014) David Olagnier et al.   PLoS Pathogens

Pharmacological inhibition of cystine–glutamate exchange induces endoplasmic reticulum stress and ferroptosis

(2014) Scott J Dixon et al.   eLife

Reactive oxygen species at the crossroads of inflammasome and inflammation

(2014) Anantha Harijith et al.   Frontiers in Physiology

Molecular Bases for the Regulation of NKG2D Ligands in Cancer

(2014) Leticia Huergo-Zapico et al.   Frontiers in Immunology

Cross-Talks between Natural Killer Cells and Distinct Subsets of Dendritic Cells

(2014) Guido Ferlazzo et al.   Frontiers in Immunology

STING-dependent cytosolic DNA sensor pathways regulate NKG2D ligand expression

(2014) Nina Le Bert et al.   OncoImmunology

Necroptosis in Immunity and Ischemia-Reperfusion Injury

(2013) A. Linkermann et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Regulation of Ligands for the NKG2D Activating Receptor

(2013) David H. Raulet et al.   Annual Review of Immunology

Cell-Death-Associated Molecular Patterns As Determinants of Cancer Immunogenicity

(2013) Sylvain Ladoire et al.   ANTIOXIDANTS & REDOX SIGNALING

DAMPs and autophagy

(2013) Qiuhong Zhang et al.   Autophagy

ROS-induced autophagy in cancer cells assists in evasion from determinants of immunogenic cell death

(2013) Abhishek D. Garg et al.   Autophagy

The NLRP3 inflammasome is up-regulated in cardiac fibroblasts and mediates myocardial ischaemia–reperfusion injury

(2013) Øystein Sandanger et al.   CARDIOVASCULAR RESEARCH

Blebs produced by actin–myosin contraction during apoptosis release damage-associated molecular pattern proteins before secondary necrosis occurs

(2013) G R Wickman et al.   CELL DEATH AND DIFFERENTIATION

Molecular mechanisms of ATP secretion during immunogenic cell death

(2013) I Martins et al.   CELL DEATH AND DIFFERENTIATION

Cancer therapeutics: Targeting the apoptotic pathway

(2013) Khurum H. Khan et al.   CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY

Transient receptor potential vanilloid-2 mediates the effects of transient heat shock on endocytosis of human monocyte-derived dendritic cells

(2013) Attila Gábor Szöllősi et al.   FEBS LETTERS

Necroptosis: The Release of Damage-Associated Molecular Patterns and Its Physiological Relevance

(2013) Agnieszka Kaczmarek et al.   IMMUNITY

Autophagy and Cellular Immune Responses

(2013) Yuting Ma et al.   IMMUNITY

The interferon response to intracellular DNA: Why so many receptors?

(2013) Leonie Unterholzner   IMMUNOBIOLOGY

Endoplasmic reticulum stress is sufficient for the induction of IL-1β production via activation of the NF-κB and inflammasome pathways

(2013) Sena Kim et al.   Innate Immunity

Molecular markers of programmed cell death in donor hearts before transplantation

(2013) Silvana F. Marasco et al.   JOURNAL OF HEART AND LUNG TRANSPLANTATION

Brain death induces renal expression of heme oxygenase-1 and heat shock protein 70

(2013) Leon FA van Dullemen et al.   Journal of Translational Medicine

Oxidative stress and apoptosis in a pig model of brain death (BD) and living donation (LD)

(2013) Philipp Stiegler et al.   Journal of Translational Medicine

Attenuation of Myocardial Injury by HMGB1 Blockade during Ischemia/Reperfusion Is Toll-Like Receptor 2-Dependent

(2013) Jan Mersmann et al.   MEDIATORS OF INFLAMMATION

S100A8 and S100A9: DAMPs at the Crossroads between Innate Immunity, Traditional Risk Factors, and Cardiovascular Disease

(2013) Alexandru Schiopu et al.   MEDIATORS OF INFLAMMATION

The Membrane-Associated Transient Receptor Potential Vanilloid Channel Is the Central Heat Shock Receptor Controlling the Cellular Heat Shock Response in Epithelial Cells

(2013) Zohar Bromberg et al.   PLoS One

Calreticulin surface exposure is abrogated in cells lacking, chaperone-mediated autophagy-essential gene, LAMP2A

(2013) A D Garg et al.   Cell Death & Disease

The Innate Immune System and Transplantation

(2013) C. A. Farrar et al.   Cold Spring Harbor Perspectives in Medicine

Signalling C-Type Lectins in Antimicrobial Immunity

(2013) Rebecca A. Drummond et al.   PLoS Pathogens

Recognition of damage-associated molecular patterns related to nucleic acids during inflammation and vaccination

(2013) Nao Jounai et al.   Frontiers in Cellular and Infection Microbiology

Nucleic acids and endosomal pattern recognition: how to tell friend from foe?

(2013) Eva Brencicova et al.   Frontiers in Cellular and Infection Microbiology

HMGB1: The Central Cytokine for All Lymphoid Cells

(2013) Guanqiao Li et al.   Frontiers in Immunology

ATP release and purinergic signaling in NLRP3 inflammasome activation

(2013) Aurélie Gombault et al.   Frontiers in Immunology

Functions of NOD-Like Receptors in Human Diseases

(2013) Yifei Zhong et al.   Frontiers in Immunology

An Update on PYRIN Domain-Containing Pattern Recognition Receptors: From Immunity to Pathology

(2013) Rojo A. Ratsimandresy et al.   Frontiers in Immunology

The Dendritic Cell Response to Classic, Emerging, and Homeostatic Danger Signals. Implications for Autoimmunity

(2013) Paul M. Gallo et al.   Frontiers in Immunology

Chronic allograft dysfunction: A model disorder of innate immunity

(2013) WalterGottlieb Land   Biomedical Journal

The innate immune response to products of phospholipid peroxidation

(2012) David Weismann et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Mixed Lineage Kinase Domain-like Protein Mediates Necrosis Signaling Downstream of RIP3 Kinase

(2012) Liming Sun et al.   CELL

IRE1α Induces Thioredoxin-Interacting Protein to Activate the NLRP3 Inflammasome and Promote Programmed Cell Death under Irremediable ER Stress

(2012) Alana G. Lerner et al.   Cell Metabolism

Human Pancreatic Islet Preparations Release HMGB1: (Ir)Relevance for Graft Engraftment

(2012) Rita Nano et al.   CELL TRANSPLANTATION

A novel pathway combining calreticulin exposure and ATP secretion in immunogenic cancer cell death

(2012) Abhishek D Garg et al.   EMBO JOURNAL

Molecules and their functions in autophagy

(2012) Jong-Ok Pyo et al.   EXPERIMENTAL AND MOLECULAR MEDICINE

HSP60 is transported through the secretory pathway of 3-MCA-induced fibrosarcoma tumour cells and undergoes N-glycosylation

(2012) Dana Hayoun et al.   FEBS Journal

Crosstalk between Toll like receptors and C5a receptor in human monocyte derived DCs suppress inflammatory cytokine production

(2012) Anouk Zaal et al.   IMMUNOBIOLOGY

Endoplasmic reticulum stress and its regulator XBP-1 contributes to dendritic cell maturation and activation induced by high mobility group box-1 protein

(2012) Xiao-mei Zhu et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

The impact of the unfolded protein response on human disease

(2012) Shiyu Wang et al.   JOURNAL OF CELL BIOLOGY

Alarmins: awaiting a clinical response

(2012) James K. Chan et al.   JOURNAL OF CLINICAL INVESTIGATION

C3a and C5a Promote Renal Ischemia-Reperfusion Injury

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Oxidative genome damage and its repair: Implications in aging and neurodegenerative diseases

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Caspase-3-Independent Internucleosomal DNA Fragmentation in Ischemic Acute Kidney Injury

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Toll-Like Receptor 4 in Experimental Kidney Transplantation: Early Mediator of Endogenous Danger Signals

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Primary Effusion Lymphoma Cell Death Induced by Bortezomib and AG 490 Activates Dendritic Cells through CD91

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ATP Release from Dying Autophagic Cells and Their Phagocytosis Are Crucial for Inflammasome Activation in Macrophages

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Endoplasmic Reticulum Stress Modulates Liver Inflammatory Immune Response in the Pathogenesis of Liver Ischemia and Reperfusion Injury

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Calreticulin in the immune system: ins and outs

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Role of Heat Shock Protein 70 in Innate Alloimmunity

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Crosstalk between Complement and Toll-like Receptor Activation in Relation to Donor Brain Death and Renal Ischemia-Reperfusion Injury

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Oxidation-Specific Epitopes Are Danger-Associated Molecular Patterns Recognized by Pattern Recognition Receptors of Innate Immunity

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Sensing disease and danger: A survey of vertebrate PRRs and their origins

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Effect of Donor JNK Signal Transduction Inhibition on Transplant Outcome in Brain Dead Rat Model

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Human Dendritic Cell Subsets from Spleen and Blood Are Similar in Phenotype and Function but Modified by Donor Health Status

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Reactive Carbonyls Are a Major Th2-Inducing Damage-Associated Molecular Pattern Generated by Oxidative Stress

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Pathogenic Natural Antibodies Propagate Cerebral Injury Following Ischemic Stroke in Mice

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Toll-like receptor 4 engagement contributes to expression of NKG2D ligands by renal tubular epithelial cells

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(2011) Koen Raedschelders et al.   PHARMACOLOGY & THERAPEUTICS

Hyaluronan as an Immune Regulator in Human Diseases

(2011) Dianhua Jiang et al.   PHYSIOLOGICAL REVIEWS

Mechanisms of Rejection: Current Perspectives

(2011) Kathryn J. Wood et al.   TRANSPLANTATION

Kidney Ischemic Injury Genes Expressed After Donor Brain Death Are Predictive for the Outcome of Kidney Transplantation

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BRCA1 is an essential regulator of heart function and survival following myocardial infarction

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NKG2D and its ligands: active factors in the outcome of solid organ transplantation?

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Extracellular heat shock protein HSP90β secreted by MG63 osteosarcoma cells inhibits activation of latent TGF-β1

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Extracellular matrix molecules: endogenous danger signals as new drug targets in kidney diseases

(2010) Liliana Schaefer   CURRENT OPINION IN PHARMACOLOGY

Transcriptional Regulation of the Endogenous Danger Signal Tenascin-C: A Novel Autocrine Loop in Inflammation

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ATF6 is important under both pathological and physiological states in the heart

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HIF-1α accumulation upregulates MICA and MICB expression on human cardiomyocytes and enhances NK cell cytotoxicity during hypoxia-reoxygenation

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The DNA Damage Response: Making It Safe to Play with Knives

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Circulating mitochondrial DAMPs cause inflammatory responses to injury

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Hsp60 Is Actively Secreted by Human Tumor Cells

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Nox isoforms in vascular pathophysiology: insights from transgenic and knockout mouse models

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Mitochondrial complex III: An essential component of universal oxygen sensing machinery?

(2010) Navdeep S. Chandel   RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY

Intravascular Danger Signals Guide Neutrophils to Sites of Sterile Inflammation

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Contribution of Toll-Like Receptor Activation to Lung Damage After Donor Brain Death

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Mechanisms and Implications of Reactive Oxygen Species Generation During the Unfolded Protein Response: Roles of Endoplasmic Reticulum Oxidoreductases, Mitochondrial Electron Transport, and NADPH Oxidase

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Phosphorylation-Driven Assembly of the RIP1-RIP3 Complex Regulates Programmed Necrosis and Virus-Induced Inflammation

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Toll-like receptor 9 inhibition confers protection from liver ischemia-reperfusion injury

(2009) Zubin M. Bamboat et al.   HEPATOLOGY

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NLRP3/Cryopyrin Is Necessary for Interleukin-1β (IL-1β) Release in Response to Hyaluronan, an Endogenous Trigger of Inflammation in Response to Injury

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(2009) Stephen P. Jackson et al.   NATURE

Nucleotides released by apoptotic cells act as a find-me signal to promote phagocytic clearance

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Thioredoxin-interacting protein links oxidative stress to inflammasome activation

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Activation of the NLRP3 inflammasome in dendritic cells induces IL-1β–dependent adaptive immunity against tumors

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Donor Toll-like receptor 4 contributes to ischemia and reperfusion injury following human kidney transplantation

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RIP3, an Energy Metabolism Regulator That Switches TNF-Induced Cell Death from Apoptosis to Necrosis

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Hyaluronic acid fragments evoke Kupffer cells via TLR4 signaling pathway

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Ischemia-mediated aggregation of the actin cytoskeleton is one of the major initial events resulting in ischemia-reperfusion injury

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Early Events in Kidney Donation: Progression of Endothelial Activation, Oxidative Stress and Tubular Injury After Brain Death

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(2008) Lorenzo Galluzzi et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

ATM-ATR-dependent up-regulation of DNAM-1 and NKG2D ligands on multiple myeloma cells by therapeutic agents results in enhanced NK-cell susceptibility and is associated with a senescent phenotype

(2008) A. Soriani et al.   BLOOD

Autophagy regulates selective HMGB1 release in tumor cells that are destined to die

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The co-translocation of ERp57 and calreticulin determines the immunogenicity of cell death

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Human spleen contains different subsets of dendritic cells and regulatory T lymphocytes

(2008) M. M. Velásquez-Lopera et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Antioxidant defense in hepatic ischemia-reperfusion injury is regulated by damage-associated molecular pattern signal molecules

(2008) Michal Pardo et al.   FREE RADICAL BIOLOGY AND MEDICINE

The Mechanism of Mitochondrial Superoxide Production by the Cytochromebc1Complex

(2008) Stefan Dröse et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Molecular Approach to Apoptosis in the Human Heart During Brain Death

(2008) Silvia Pérez López et al.   TRANSPLANTATION

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(2008) Hans U. Lutz et al.   TRENDS IN IMMUNOLOGY

In vivo reactive oxygen species production induced by ischemia in muscle arterioles of mice: involvement of xanthine oxidase and mitochondria

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Apoptosis: controlled demolition at the cellular level

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