Cell stress increases ATP release in NLRP3 inflammasome-mediated autoinflammatory diseases, resulting in cytokine imbalance

IL-1 Blockade in Autoinflammatory Syndromes

(2014) Adriana A. Jesus et al.   Annual Review of Medicine

Mechanisms and Functions of Inflammasomes

(2014) Mohamed Lamkanfi et al.   CELL

Autoinflammatory diseases

(2014) Anna Rubartelli   IMMUNOLOGY LETTERS

A Key Role for Redox Signaling in Rapid P2X7 Receptor-Induced IL-1  Processing in Human Monocytes

(2014) J. Hewinson et al.   JOURNAL OF IMMUNOLOGY

TLR Costimulation Causes Oxidative Stress with Unbalance of Proinflammatory and Anti-Inflammatory Cytokine Production

(2014) R. Lavieri et al.   JOURNAL OF IMMUNOLOGY

Nonmetal Haptens Induce ATP Release from Keratinocytes through Opening of Pannexin Hemichannels by Reactive Oxygen Species

(2014) Kaoru Onami et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Src-dependent impairment of autophagy by oxidative stress in a mouse model of Duchenne muscular dystrophy

(2014) Rituraj Pal et al.   Nature Communications

Increased NLRP3-dependent interleukin 1β secretion in patients with familial Mediterranean fever: correlation withMEFVgenotype

(2013) Alessia Omenetti et al.   ANNALS OF THE RHEUMATIC DISEASES

C3a modulates IL-1  secretion in human monocytes by regulating ATP efflux and subsequent NLRP3 inflammasome activation

(2013) E. Asgari et al.   BLOOD

Potential Impact of Genetic Variants in Nrf2 Regulated Antioxidant Genes and Risk Prediction of Diabetes and Associated Cardiac Complications

(2013) T. Ramprasath et al.   CURRENT MEDICINAL CHEMISTRY

The Interleukin-1 Family: Back to the Future

(2013) Cecilia Garlanda et al.   IMMUNITY

CD39 and CD73 in immunity and inflammation

(2013) Luca Antonioli et al.   TRENDS IN MOLECULAR MEDICINE

Deficient production of IL-1 receptor antagonist and IL-6 coupled to oxidative stress in cryopyrin-associated periodic syndrome monocytes

(2012) Sonia Carta et al.   ANNALS OF THE RHEUMATIC DISEASES

Microarray-based gene expression profiling in patients with cryopyrin-associated periodic syndromes defines a disease-related signature and IL-1-responsive transcripts

(2012) James E Balow et al.   ANNALS OF THE RHEUMATIC DISEASES

Inflammasome Activators Induce Interleukin-1α Secretion via Distinct Pathways with Differential Requirement for the Protease Function of Caspase-1

(2012) Olaf Groß et al.   IMMUNITY

The calcium-sensing receptor regulates the NLRP3 inflammasome through Ca2+ and cAMP

(2012) Geun-Shik Lee et al.   NATURE

The oxidative stress-inducible cystine/glutamate antiporter, system x c − : cystine supplier and beyond

(2011) Marcus Conrad et al.   AMINO ACIDS

Interleukin-1 in the pathogenesis and treatment of inflammatory diseases

(2011) C. A. Dinarello   BLOOD

The Rate of Interleukin-1β Secretion in Different Myeloid Cells Varies with the Extent of Redox Response to Toll-like Receptor Triggering

(2011) Sonia Carta et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mitochondrial reactive oxygen species promote production of proinflammatory cytokines and are elevated in TNFR1-associated periodic syndrome (TRAPS)

(2011) Ariel C. Bulua et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Pannexin-1 Is Required for ATP Release during Apoptosis but Not for Inflammasome Activation

(2011) Y. Qu et al.   JOURNAL OF IMMUNOLOGY

Cutting Edge: Reactive Oxygen Species Inhibitors Block Priming, but Not Activation, of the NLRP3 Inflammasome

(2011) F. Bauernfeind et al.   JOURNAL OF IMMUNOLOGY

Regulation of Translation by Hydrogen Peroxide

(2010) Chris M. Grant   ANTIOXIDANTS & REDOX SIGNALING

Clinical presentation and pathogenesis of cold-induced autoinflammatory disease in a family with recurrence of an NLRP12 mutation

(2010) S. Borghini et al.   ARTHRITIS AND RHEUMATISM

Concerted action of wild-type and mutant TNF receptors enhances inflammation in TNF receptor 1-associated periodic fever syndrome

(2010) A. Simon et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Altered redox state of monocytes from cryopyrin-associated periodic syndromes causes accelerated IL-1  secretion

(2010) S. Tassi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Inflammasomes: Guardians of the Body

(2009) Fabio Martinon et al.   Annual Review of Immunology

Pathogen-Induced Interleukin-1  Processing and Secretion Is Regulated by a Biphasic Redox Response

(2009) S. Tassi et al.   JOURNAL OF IMMUNOLOGY

Differential requirement for the activation of the inflammasome for processing and release of IL-1  in monocytes and macrophages

(2008) M. G. Netea et al.   BLOOD

Requirement of Reactive Oxygen Species-dependent Activation of ASK1-p38 MAPK Pathway for Extracellular ATP-induced Apoptosis in Macrophage

(2008) Takuya Noguchi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

ATP is released by monocytes stimulated with pathogen-sensing receptor ligands and induces IL-1  and IL-18 secretion in an autocrine way

(2008) A. Piccini et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA