The Alarmin Concept Applied to Human Renal Transplantation: Evidence for a Differential Implication of HMGB1 and IL-33

Interleukin-33 Is hepatoprotective during liver ischemia/reperfusion in mice

(2012) Nozomu Sakai et al.   HEPATOLOGY

New strategies to optimize kidney recovery and preservation in transplantation

(2012) Delphine Bon et al.   Nature Reviews Nephrology

Interleukin-33 and the function of innate lymphoid cells

(2012) Ananda S. Mirchandani et al.   TRENDS IN IMMUNOLOGY

Infection with Influenza Virus Induces IL-33 in Murine Lungs

(2011) Ronan Le Goffic et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Characterization of Interleukin-33 and Soluble ST2 in Serum and Their Association with Disease Severity in Patients with Chronic Kidney Disease

(2011) Yu-Shi Bao et al.   JOURNAL OF CLINICAL IMMUNOLOGY

IL-33 Expands Suppressive CD11b+ Gr-1int and Regulatory T Cells, including ST2L+ Foxp3+ Cells, and Mediates Regulatory T Cell-Dependent Promotion of Cardiac Allograft Survival

(2011) H. R. Turnquist et al.   JOURNAL OF IMMUNOLOGY

IL-33 Exacerbates Acute Kidney Injury

(2011) A. Akcay et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Ischemia and reperfusion—from mechanism to translation

(2011) Holger K Eltzschig et al.   NATURE MEDICINE

Sustained elevation of interleukin-33 in sera and synovial fluids from patients with rheumatoid arthritis non-responsive to anti-tumor necrosis factor: possible association with persistent IL-1β signaling and a poor clinical response

(2011) Yasushi Matsuyama et al.   RHEUMATOLOGY INTERNATIONAL

Interleukin-33 prolongs allograft survival during chronic cardiac rejection

(2011) Stefan M. Brunner et al.   TRANSPLANT INTERNATIONAL

Islet-expressed TLR2 and TLR4 sense injury and mediate early graft failure after transplantation

(2010) Bernd Krüger et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

A natural protective function of invariant NKT cells in a mouse model of innate-cell-driven lung inflammation

(2010) Elvire A. Bourgeois et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

High-mobility group box 1 is involved in the initial events of early loss of transplanted islets in mice

(2010) Nobuhide Matsuoka et al.   JOURNAL OF CLINICAL INVESTIGATION

HMGB1 Contributes to Kidney Ischemia Reperfusion Injury

(2010) H. Wu et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Toll-like receptor 4 regulates early endothelial activation during ischemic acute kidney injury

(2010) Jianlin Chen et al.   KIDNEY INTERNATIONAL

Release of Danger Signals during Ischemic Storage of the Liver: A Potential Marker of Organ Damage?

(2010) Anding Liu et al.   MEDIATORS OF INFLAMMATION

Neutralization of the extracellular HMGB1 released by ischaemic-damaged renal cells protects against renal ischaemia-reperfusion injury

(2010) J. Li et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

IL-33 is a crucial amplifier of innate rather than acquired immunity

(2010) K. Oboki et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IL-33 Prolongs Murine Cardiac Allograft Survival Through Induction of TH2-Type Immune Deviation

(2010) Hui Yin et al.   TRANSPLANTATION

The pro-Th2 cytokine IL-33 directly interacts with invariant NKT and NK cells to induce IFN-γ production

(2009) Elvire Bourgeois et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Donor Toll-like receptor 4 contributes to ischemia and reperfusion injury following human kidney transplantation

(2009) B. Kruger et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Interleukin-33 – cytokine of dual function or novel alarmin?

(2009) Guttorm Haraldsen et al.   TRENDS IN IMMUNOLOGY

Soluble ST2 Levels Are Associated with Bleeding in Patients with Severe Leptospirosis

(2009) Jiri F. P. Wagenaar et al.   PLoS Neglected Tropical Diseases

IL-33 amplifies both Th1- and Th2-type responses through its activity on human basophils, allergen-reactive Th2 cells, iNKT and NK Cells

(2008) M. D. Smithgall et al.   INTERNATIONAL IMMUNOLOGY

The IL-1-Like Cytokine IL-33 Is Constitutively Expressed in the Nucleus of Endothelial Cells and Epithelial Cells In Vivo: A Novel ‘Alarmin’?

(2008) Christine Moussion et al.   PLoS One