Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Property of Lysosomal Storage Disease Associated with Midbrain Pathology in the Central Nervous System of Lamp-2–Deficient Mice

(2015) Akiko Furuta et al.   AMERICAN JOURNAL OF PATHOLOGY

Myocardial autophagic energy stress responses—macroautophagy, mitophagy, and glycophagy

(2015) Lea M. D. Delbridge et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

The integral membrane protein ITM2A, a transcriptional target of PKA-CREB, regulates autophagic flux via interaction with the vacuolar ATPase

(2015) Sim Namkoong et al.   Autophagy

Rph1 mediates the nutrient-limitation signaling pathway leading to transcriptional activation of autophagy

(2015) Amélie Bernard et al.   Autophagy

DrosophilaGyf/GRB10 interacting GYF protein is an autophagy regulator that controls neuron and muscle homeostasis

(2015) Myungjin Kim et al.   Autophagy

Autophagy Regulatory Network — A systems-level bioinformatics resource for studying the mechanism and regulation of autophagy

(2015) Dénes Türei et al.   Autophagy

TNFAIP3 promotes survival of CD4 T cells by restricting MTOR and promoting autophagy

(2015) Yu Matsuzawa et al.   Autophagy

SIRT5 regulation of ammonia-induced autophagy and mitophagy

(2015) Lucia Polletta et al.   Autophagy

Modulation of inflammation by autophagy: Consequences for human disease

(2015) Romana T. Netea-Maier et al.   Autophagy

The problem of pyridinyl imidazole class inhibitors of MAPK14/p38α and MAPK11/p38β in autophagy research

(2015) Manoj B Menon et al.   Autophagy

New method to assess mitophagy flux by flow cytometry

(2015) Marta Mauro-Lizcano et al.   Autophagy

SIRT3-SOD2-mROS-dependent autophagy in cadmium-induced hepatotoxicity and salvage by melatonin

(2015) Huifeng Pi et al.   Autophagy

Ultrastructural relationship of the phagophore with surrounding organelles

(2015) Joanna Biazik et al.   Autophagy

An RNautophagy/DNautophagy receptor, LAMP2C, possesses an arginine-rich motif that mediates RNA/DNA-binding

(2015) Yuuki Fujiwara et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Novel role for TRPC4 in regulation of macroautophagy by a small molecule in vascular endothelial cells

(2015) Lu Zhang et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Degradation of AMPK by a Cancer-Specific Ubiquitin Ligase

(2015) Carlos T. Pineda et al.   CELL

Autophagy in Vascular Disease

(2015) G. R. Y. De Meyer et al.   CIRCULATION RESEARCH

Rph1/KDM4 Mediates Nutrient-Limitation Signaling that Leads to the Transcriptional Induction of Autophagy

(2015) Amélie Bernard et al.   CURRENT BIOLOGY

WHAMM Directs the Arp2/3 Complex to the ER for Autophagosome Biogenesis through an Actin Comet Tail Mechanism

(2015) David J. Kast et al.   CURRENT BIOLOGY

Iron-Starvation-Induced Mitophagy Mediates Lifespan Extension upon Mitochondrial Stress in C. elegans

(2015) Alfonso Schiavi et al.   CURRENT BIOLOGY

Secretory autophagy

(2015) Marisa Ponpuak et al.   CURRENT OPINION IN CELL BIOLOGY

Lipid droplets and their component triglycerides and steryl esters regulate autophagosome biogenesis

(2015) T. Shpilka et al.   EMBO JOURNAL

Impairment of chaperone-mediated autophagy leads to selective lysosomal degradation defects in the lysosomal storage disease cystinosis

(2015) G. Napolitano et al.   EMBO Molecular Medicine

Starvation-induced MTMR13 and RAB21 activity regulates VAMP8 to promote autophagosome-lysosome fusion

(2015) S. Jean et al.   EMBO REPORTS

RIP1 negatively regulates basal autophagic flux through TFEB to control sensitivity to apoptosis

(2015) T. Yonekawa et al.   EMBO REPORTS

Autophagic bulk sequestration of cytosolic cargo is independent of LC3, but requires GABARAPs

(2015) Paula Szalai et al.   EXPERIMENTAL CELL RESEARCH

Novel steps in the autophagic-lysosomal pathway

(2015) Frank Saetre et al.   FEBS Journal

Unbiased Cell-based Screening in a Neuronal Cell Model of Batten Disease Highlights an Interaction between Ca2+Homeostasis, Autophagy, and CLN3 Protein Function

(2015) Uma Chandrachud et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Pharmacological Inhibition of ULK1 Kinase Blocks Mammalian Target of Rapamycin (mTOR)-dependent Autophagy

(2015) Katy J. Petherick et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

TRIM-mediated precision autophagy targets cytoplasmic regulators of innate immunity

(2015) Tomonori Kimura et al.   JOURNAL OF CELL BIOLOGY

MiT/TFE transcription factors are activated during mitophagy downstream of Parkin and Atg5

(2015) Catherine L. Nezich et al.   JOURNAL OF CELL BIOLOGY

Degradation of HK2 by chaperone-mediated autophagy promotes metabolic catastrophe and cell death

(2015) Hong-guang Xia et al.   JOURNAL OF CELL BIOLOGY

Autophagy and mitochondrial remodelling in mouse mesenchymal stromal cells challenged withStaphylococcus epidermidis

(2015) Nikolai V. Gorbunov et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

GABARAP is a determinant of apoptosis in growth-arrested chicken embryo fibroblasts

(2015) Scott Maynard et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Suppression of Autophagy Dysregulates the Antioxidant Response and Causes Premature Senescence of Melanocytes

(2015) Cheng-Feng Zhang et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Macroautophagic cargo sequestration assays

(2015) Per O. Seglen et al.   METHODS

How and why to study autophagy in Drosophila: It’s more than just a garbage chute

(2015) Péter Nagy et al.   METHODS

Autophagic flux determination in vivo and ex vivo

(2015) Lorena Esteban-Martínez et al.   METHODS

Amino Acid-Dependent mTORC1 Regulation by the Lysosomal Membrane Protein SLC38A9

(2015) Jennifer Jung et al.   MOLECULAR AND CELLULAR BIOLOGY

Autophagy in adipose tissue of patients with obesity and type 2 diabetes

(2015) J. Kosacka et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Receptor-Bound Targets of Selective Autophagy Use a Scaffold Protein to Activate the Atg1 Kinase

(2015) Roarke A. Kamber et al.   MOLECULAR CELL

PLEKHM1 Regulates Autophagosome-Lysosome Fusion through HOPS Complex and LC3/GABARAP Proteins

(2015) David G. McEwan et al.   MOLECULAR CELL

ESCRTs Cooperate with a Selective Autophagy Receptor to Mediate Vacuolar Targeting of Soluble Cargos

(2015) Xiao-Man Liu et al.   MOLECULAR CELL

Autophagic Degradation of the 26S Proteasome Is Mediated by the Dual ATG8/Ubiquitin Receptor RPN10 in Arabidopsis

(2015) Richard S. Marshall et al.   MOLECULAR CELL

mTORC1 Phosphorylates UVRAG to Negatively Regulate Autophagosome and Endosome Maturation

(2015) Young-Mi Kim et al.   MOLECULAR CELL

Lysosomal mTORC2/PHLPP1/Akt Regulate Chaperone-Mediated Autophagy

(2015) Esperanza Arias et al.   MOLECULAR CELL

Phosphorylation of LC3 by the Hippo Kinases STK3/STK4 Is Essential for Autophagy

(2015) Deepti S. Wilkinson et al.   MOLECULAR CELL

Coordination of mitophagy and mitochondrial biogenesis during ageing in C. elegans

(2015) Konstantinos Palikaras et al.   NATURE

Regulation of endoplasmic reticulum turnover by selective autophagy

(2015) Aliaksandr Khaminets et al.   NATURE

Receptor-mediated selective autophagy degrades the endoplasmic reticulum and the nucleus

(2015) Keisuke Mochida et al.   NATURE

Transcriptional control of autophagy–lysosome function drives pancreatic cancer metabolism

(2015) Rushika M. Perera et al.   NATURE

SLC38A9 is a component of the lysosomal amino acid sensing machinery that controls mTORC1

(2015) Manuele Rebsamen et al.   NATURE

A conserved mechanism of TOR-dependent RCK-mediated mRNA degradation regulates autophagy

(2015) Guowu Hu et al.   NATURE CELL BIOLOGY

Lysosomal calcium signalling regulates autophagy through calcineurin and TFEB

(2015) Diego L. Medina et al.   NATURE CELL BIOLOGY

ATG12–ATG3 interacts with Alix to promote basal autophagic flux and late endosome function

(2015) Lyndsay Murrow et al.   NATURE CELL BIOLOGY

The Roles of PINK1, Parkin, and Mitochondrial Fidelity in Parkinson’s Disease

(2015) Alicia M. Pickrell et al.   NEURON

RNautophagy/DNautophagy possesses selectivity for RNA/DNA substrates

(2015) Katsunori Hase et al.   NUCLEIC ACIDS RESEARCH

Caffeine impairs resection during DNA break repair by reducing the levels of nucleases Sae2 and Dna2

(2015) Michael Tsabar et al.   NUCLEIC ACIDS RESEARCH

A novel quantitative assay of mitophagy: Combining high content fluorescence microscopy and mitochondrial DNA load to quantify mitophagy and identify novel pharmacological tools against pathogenic heteroplasmic mtDNA

(2015) Alan Diot et al.   PHARMACOLOGICAL RESEARCH

Autophagic Recycling Plays a Central Role in Maize Nitrogen Remobilization

(2015) Faqiang Li et al.   PLANT CELL

Neuropeptide Y stimulates autophagy in hypothalamic neurons

(2015) Célia A. Aveleira et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

GABARAPs regulate PI4P-dependent autophagosome:lysosome fusion

(2015) Hanzhi Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Lysosomal amino acid transporter SLC38A9 signals arginine sufficiency to mTORC1

(2015) S. Wang et al.   SCIENCE

Induction of oxiapoptophagy on 158N murine oligodendrocytes treated by 7-ketocholesterol-, 7β-hydroxycholesterol-, or 24(S)-hydroxycholesterol: Protective effects of α-tocopherol and docosahexaenoic acid (DHA; C22:6 n-3)

(2015) Thomas Nury et al.   STEROIDS

How to control self-digestion: transcriptional, post-transcriptional, and post-translational regulation of autophagy

(2015) Yuchen Feng et al.   TRENDS IN CELL BIOLOGY

TRB3 links insulin/IGF to tumour promotion by interacting with p62 and impeding autophagic/proteasomal degradations

(2015) Fang Hua et al.   Nature Communications

Autophagosome–lysosome fusion is independent of V-ATPase-mediated acidification

(2015) Caroline Mauvezin et al.   Nature Communications

Bcl-2-like protein 13 is a mammalian Atg32 homologue that mediates mitophagy and mitochondrial fragmentation

(2015) Tomokazu Murakawa et al.   Nature Communications

Placental Adaptations in Growth Restriction

(2015) Song Zhang et al.   Nutrients

Parallel damage in mitochondrial and lysosomal compartments promotes efficient cell death with autophagy: The case of the pentacyclic triterpenoids

(2015) Waleska K. Martins et al.   Scientific Reports

The nucleolar protein nucleophosmin is essential for autophagy induced by inhibiting Pol I transcription

(2015) Naohiro Katagiri et al.   Scientific Reports

Synthetic Quantitative Array Technology Identifies the Ubp3-Bre5 Deubiquitinase Complex as a Negative Regulator of Mitophagy

(2015) Matthias Müller et al.   Cell Reports

Systems Biology of Tissue-Specific Response to Anaplasma phagocytophilum Reveals Differentiated Apoptosis in the Tick Vector Ixodes scapularis

(2015) Nieves Ayllón et al.   PLoS Genetics

Yip1A, a Novel Host Factor for the Activation of the IRE1 Pathway of the Unfolded Protein Response during Brucella Infection

(2015) Yuki Taguchi et al.   PLoS Pathogens

Changing Shapes of Glycogen–Autophagy Nexus in Neurons: Perspective from a Rare Epilepsy

(2015) Pankaj Kumar Singh et al.   Frontiers in Neurology

LAMP-2 deficiency leads to hippocampal dysfunction but normal clearance of neuronal substrates of chaperone-mediated autophagy in a mouse model for Danon disease

(2015) Michelle Rothaug et al.   Acta Neuropathologica Communications

Multiple functions of the SNARE protein Snap29 in autophagy, endocytic, and exocytic trafficking during epithelial formation inDrosophila

(2015) Elena Morelli et al.   Autophagy

Loss of functional MYO1C/myosin 1c, a motor protein involved in lipid raft trafficking, disrupts autophagosome-lysosome fusion

(2015) Hemma Brandstaetter et al.   Autophagy

The mitochondrial citrate transporter, CIC, is essential for mitochondrial homeostasis.

(2015) Olga Catalina-Rodriguez et al.   Oncotarget

Atg7- and Keap1-dependent autophagy protects breast cancer cell lines against mitoquinone-induced oxidative stress

(2015) Yanira Gonzalez et al.   Oncotarget

Zebrafish models of BAG3 myofibrillar myopathy suggest a toxic gain of function leading to BAG3 insufficiency

(2014) Avnika A. Ruparelia et al.   ACTA NEUROPATHOLOGICA

Involvement of oxysterols in age-related diseases and ageing processes

(2014) Amira Zarrouk et al.   AGEING RESEARCH REVIEWS

Concomitant Induction of Apoptosis and Autophagy by Prostate Apoptosis Response-4 in Hypopharyngeal Carcinoma Cells

(2014) Ling-Jung Wang et al.   AMERICAN JOURNAL OF PATHOLOGY

Extracellular membrane vesicles as a mechanism of cell-to-cell communication: advantages and disadvantages

(2014) Giuseppina Turturici et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Cardiomyocyte glycophagy is regulated by insulin and exposure to high extracellular glucose

(2014) Kimberley M. Mellor et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Autophagy is essential to support skeletal muscle plasticity in response to endurance exercise

(2014) Anthony M. J. Sanchez et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Autophagy and Its Normal and Pathogenic States in the Brain

(2014) Ai Yamamoto et al.   Annual Review of Neuroscience

The plant alkaloid voacamine induces apoptosis-independent autophagic cell death on both sensitive and multidrug resistant human osteosarcoma cells

(2014) Stefania Meschini et al.   Autophagy

The non-canonical role of Atg family members as suppressors of innate antiviral immune signaling

(2014) Fumihiko Takeshita et al.   Autophagy

Caffeine induces macroautophagy and confers a cytocidal effect on food spoilage yeast in combination with benzoic acid

(2014) Gal Winter et al.   Autophagy

Quantitation of autophagy by luciferase release assay

(2014) Robin Ketteler et al.   Autophagy

A novel mammalian trans-membrane protein reveals an alternative initiation pathway for autophagy

(2014) Maria I. Vaccaro et al.   Autophagy

Mitochondrially localized ERK2 regulates mitophagy and autophagic cell stress

(2014) Ruben K. Dagda et al.   Autophagy

A method to measure cardiac autophagic flux in vivo

(2014) Eri Iwai-Kanai et al.   Autophagy

Different modes of programmed cell death during oogenesis of the silkmothBombyx mori

(2014) Vicky E. Mpakou et al.   Autophagy

Non-canonical autophagy: An exception or an underestimated form of autophagy?

(2014) Francesca Scarlatti et al.   Autophagy

The effects of p53 on whole organism longevity are mediated by autophagy

(2014) Nektarios Tavernarakis et al.   Autophagy

The PI 3-kinase regulator Vps15 is required for autophagic clearance of protein aggregates

(2014) Karine Lindmo et al.   Autophagy

Some autophagic and apoptotic features of programmed cell death in the anterior silk glands of the silkworm,Bombyx mori

(2014) Ebru Goncu et al.   Autophagy

Downregulation of autophagy by herpesvirus Bcl-2 homologs

(2014) Chengyu Liang et al.   Autophagy

Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes

(2014) Daniel J. Klionsky et al.   Autophagy

Macroautophagy-dependent, intralysosomal cleavage of a betaine homocysteine methyltransferase fusion protein requires stable multimerization

(2014) Carol A. Mercer et al.   Autophagy

Longevity pathways converge on autophagy genes to regulate life span inCaenorhabditis elegans

(2014) Márton L. Tóth et al.   Autophagy

Rosella: A fluorescent pH-biosensor for reporting vacuolar turnover of cytosol and organelles in yeast

(2014) Carlos Rosado et al.   Autophagy

The autophagy geneATG5plays an essential role in B lymphocyte development

(2014) Brian C. Miller et al.   Autophagy

Utilizing flow cytometry to monitor autophagy in living mammalian cells

(2014) Elena Shvets et al.   Autophagy

Does bafilomycin A1block the fusion of autophagosomes with lysosomes?

(2014) Daniel J. Klionsky et al.   Autophagy

Anti-cancer agent siramesine is a lysosomotropic detergent that induces cytoprotective autophagosome accumulation

(2014) Marie Stampe Ostenfeld et al.   Autophagy

To be or not to be? Examples of incorrect identification of autophagic compartments in conventional transmission electron microscopy of mammalian cells

(2014) Eeva-Liisa Eskelinen   Autophagy

HspB8 and Bag3: A new chaperone complex targeting misfolded proteins to macroautophagy

(2014) Serena Carra et al.   Autophagy

Dual Role of JNK1-mediated phosphorylation of Bcl-2 in autophagy and apoptosis regulation

(2014) Yongjie Wei et al.   Autophagy

Bcl-2 family members: Dual regulators of apoptosis and autophagy

(2014) Beth Levine et al.   Autophagy

Identification of autophagy genes inCiona intestinalis: A new experimental model to study autophagy mechanism

(2014) Nelly Godefroy et al.   Autophagy

Autophagy in protists: examples of secondary loss, lineage-specific innovations, and the conundrum of remodeling a single mitochondrion

(2014) Daniel J. Rigden et al.   Autophagy

Regulation of autophagy by a beclin 1-targeted microRNA, miR-30a, in cancer cells

(2014) Hua Zhu et al.   Autophagy

Evolution of Atg1 function and regulation

(2014) Edmond Y. Chan et al.   Autophagy

Role of class III phosphatidylinositol 3-kinase during programmed nuclear death ofTetrahymena thermophila

(2014) Takahiko Akematsu et al.   Autophagy

Symbiophagy and biomineralization in the “living fossil”Astrosclera willeyana

(2014) Daniel J Jackson et al.   Autophagy

Characterization of the ATG8-conjugation system in 2Plasmodiumspecies with special focus on the liver stage

(2014) Bamini Jayabalasingham et al.   Autophagy

Selective inhibition of IFNG-induced autophagy byMir155- andMir31-responsive WNT5A and SHH signaling

(2014) Sahana Holla et al.   Autophagy

ATG8 localization in apicomplexan parasites

(2014) Noboru Mizushima et al.   Autophagy

Autophagy facilitates secretion and protects against degeneration of the Harderian gland

(2014) Ulrich Koenig et al.   Autophagy

Stationary phase lipophagy as a cellular mechanism to recycle sterols during quiescence

(2014) Chao-Wen Wang   Autophagy

Atg17/FIP200 localizes to perilysosomal Ref(2)P aggregates and promotes autophagy by activation of Atg1 inDrosophila

(2014) Péter Nagy et al.   Autophagy

A role of autophagy in PTP4A3-driven cancer progression

(2014) Yu-Han Huang et al.   Autophagy

HIF1A regulates xenophagic degradation of adherent and invasiveEscherichia coli(AIEC)

(2014) Sanda Mimouna et al.   Autophagy

Expression of the autophagy substrate SQSTM1/p62 is restored during prolonged starvation depending on transcriptional upregulation and autophagy-derived amino acids

(2014) Mayurbhai Himatbhai Sahani et al.   Autophagy

Identification of Atg3 as an intrinsically disordered polypeptide yields insights into the molecular dynamics of autophagy-related proteins in yeast

(2014) Hana Popelka et al.   Autophagy

FLCN, a novel autophagy component, interacts with GABARAP and is regulated by ULK1 phosphorylation

(2014) Elaine A Dunlop et al.   Autophagy

Atg37 regulates the assembly of the pexophagic receptor protein complex

(2014) Taras Y Nazarko   Autophagy

Autophagy is essential for cardiac morphogenesis during vertebrate development

(2014) Eunmyong Lee et al.   Autophagy

Phosphorylation of NBR1 by GSK3 modulates protein aggregation

(2014) Anne-Sophie Nicot et al.   Autophagy

iLIR

(2014) Ioanna Kalvari et al.   Autophagy

A new method to measure autophagy flux in the nervous system

(2014) Soledad Matus et al.   Autophagy

Detection ofSaccharomyces cerevisiaeAtg13 by western blot

(2014) Leonor Miller-Fleming et al.   Autophagy

Identification of autophagy as a longevity-assurance mechanism in the aging modelPodospora anserina

(2014) Laura Knuppertz et al.   Autophagy

Japanese encephalitis virus replication is negatively regulated by autophagy and occurs on LC3-I- and EDEM1-containing membranes

(2014) Manish Sharma et al.   Autophagy

Caloric restriction mimetics: natural/physiological pharmacological autophagy inducers

(2014) Guillermo Mariño et al.   Autophagy

Vacuolin-1 potently and reversibly inhibits autophagosome-lysosome fusion by activating RAB5A

(2014) Yingying Lu et al.   Autophagy

ARRB1/β-arrestin-1 mediates neuroprotection through coordination of BECN1-dependent autophagy in cerebral ischemia

(2014) Pei Wang et al.   Autophagy

The progression of peroxisomal degradation through autophagy requires peroxisomal division

(2014) Kai Mao et al.   Autophagy

Posttranslational modification of autophagy-related proteins in macroautophagy

(2014) Yangchun Xie et al.   Autophagy

Acidic extracellular pH neutralizes the autophagy-inhibiting activity of chloroquine

(2014) Paola Pellegrini et al.   Autophagy

DIRAS3 regulates the autophagosome initiation complex in dormant ovarian cancer cells

(2014) Zhen Lu et al.   Autophagy

Autophagosomes, phagosomes, autolysosomes, phagolysosomes, autophagolysosomes… Wait, I’m confused

(2014) Daniel J Klionsky et al.   Autophagy

Evidence for the involvement of GD3 ganglioside in autophagosome formation and maturation

(2014) Paola Matarrese et al.   Autophagy

Autophagy plays an important role in the containment of HIV-1 in nonprogressor-infected patients

(2014) Roberta Nardacci et al.   Autophagy

TSPO interacts with VDAC1 and triggers a ROS-mediated inhibition of mitochondrial quality control

(2014) Jemma Gatliff et al.   Autophagy

Development of a novel method for quantification of autophagic protein degradation by AHA labeling

(2014) Jianbin Zhang et al.   Autophagy

NRBF2 regulates macroautophagy as a component of Vps34 Complex I

(2014) Yanyan Cao et al.   BIOCHEMICAL JOURNAL

Regulation of autophagy and mitophagy by nutrient availability and acetylation

(2014) Bradley R. Webster et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Ral small GTPase signaling and oncogenesis: More than just 15minutes of fame

(2014) Leanna R. Gentry et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Inactivation of Omi/HtrA2 protease leads to the deregulation of mitochondrial Mulan E3 ubiquitin ligase and increased mitophagy

(2014) Lucia Cilenti et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Effects of Lipid Interactions on Model Vesicle Engulfment by Alveolar Macrophages

(2014) Matthew J. Justice et al.   BIOPHYSICAL JOURNAL

The exosome complex establishes a barricade to erythroid maturation

(2014) S. C. McIver et al.   BLOOD

Immunological significance of the accumulation of autophagy components in oral squamous cell carcinoma

(2014) Koichi Sakakura et al.   CANCER SCIENCE

Metabolic Control of Autophagy

(2014) Lorenzo Galluzzi et al.   CELL

Autophagic Clearance of PolyQ Proteins Mediated by Ubiquitin-Atg8 Adaptors of the Conserved CUET Protein Family

(2014) Kefeng Lu et al.   CELL

The Diabetes Susceptibility Gene Clec16a Regulates Mitophagy

(2014) Scott A. Soleimanpour et al.   CELL

Atomistic Autophagy: The Structures of Cellular Self-Digestion

(2014) James H. Hurley et al.   CELL

Agent-based modeling of autophagy reveals emergent regulatory behavior of spatio-temporal autophagy dynamics

(2014) Christoph S Börlin et al.   Cell Communication and Signaling

Mechanism of liponecrosis, a distinct mode of programmed cell death

(2014) Vincent R Richard et al.   CELL CYCLE

Hexokinase II integrates energy metabolism and cellular protection: Akting on mitochondria and TORCing to autophagy

(2014) D J Roberts et al.   CELL DEATH AND DIFFERENTIATION

High sphingomyelin levels induce lysosomal damage and autophagy dysfunction in Niemann Pick disease type A

(2014) E Gabandé-Rodríguez et al.   CELL DEATH AND DIFFERENTIATION

The plant metacaspase AtMC1 in pathogen-triggered programmed cell death and aging: functional linkage with autophagy

(2014) N S Coll et al.   CELL DEATH AND DIFFERENTIATION

Proteasome inhibition and oxidative reactions disrupt cellular homeostasis during heme stress

(2014) F Vallelian et al.   CELL DEATH AND DIFFERENTIATION

Essential versus accessory aspects of cell death: recommendations of the NCCD 2015

(2014) L Galluzzi et al.   CELL DEATH AND DIFFERENTIATION

The Immune Receptor NOD1 and Kinase RIP2 Interact with Bacterial Peptidoglycan on Early Endosomes to Promote Autophagy and Inflammatory Signaling

(2014) Aaron T. Irving et al.   Cell Host & Microbe

The DNA Damage-Regulated Autophagy Modulator DRAM1 Links Mycobacterial Recognition via TLR-MYD88 to Autophagic Defense

(2014) Michiel van der Vaart et al.   Cell Host & Microbe

Crosstalk between the cGAS DNA Sensor and Beclin-1 Autophagy Protein Shapes Innate Antimicrobial Immune Responses

(2014) Qiming Liang et al.   Cell Host & Microbe

Screening in Planarians Identifies MORN2 as a Key Component in LC3-Associated Phagocytosis and Resistance to Bacterial Infection

(2014) Prasad Abnave et al.   Cell Host & Microbe

A LC3-Interacting Motif in the Influenza A Virus M2 Protein Is Required to Subvert Autophagy and Maintain Virion Stability

(2014) Rupert Beale et al.   Cell Host & Microbe

The Lysosomal v-ATPase-Ragulator Complex Is a Common Activator for AMPK and mTORC1, Acting as a Switch between Catabolism and Anabolism

(2014) Chen-Song Zhang et al.   Cell Metabolism

Hif-2α Promotes Degradation of Mammalian Peroxisomes by Selective Autophagy

(2014) Katharina M. Walter et al.   Cell Metabolism

Nucleocytosolic Depletion of the Energy Metabolite Acetyl-Coenzyme A Stimulates Autophagy and Prolongs Lifespan

(2014) Tobias Eisenberg et al.   Cell Metabolism

Exceptionally abundant exceptions: comprehensive characterization of intrinsic disorder in all domains of life

(2014) Zhenling Peng et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Dual role for CHOP in the crosstalk between autophagy and apoptosis to determine cell fate in response to amino acid deprivation

(2014) Wafa B'chir et al.   CELLULAR SIGNALLING

Classification of Intrinsically Disordered Regions and Proteins

(2014) Robin van der Lee et al.   CHEMICAL REVIEWS

PMI: A ΔΨm Independent Pharmacological Regulator of Mitophagy

(2014) Daniel A. East et al.   CHEMISTRY & BIOLOGY

PINK1 Triggers Autocatalytic Activation of Parkin to Specify Cell Fate Decisions

(2014) Conggang Zhang et al.   CURRENT BIOLOGY

Transcriptional Regulation by Pho23 Modulates the Frequency of Autophagosome Formation

(2014) Meiyan Jin et al.   CURRENT BIOLOGY

Neutral Lipid Stores and Lipase PNPLA5 Contribute to Autophagosome Biogenesis

(2014) Nicolas Dupont et al.   CURRENT BIOLOGY

Cytoprotective Effect of Lacritin on Human Corneal Epithelial Cells Exposed to Benzalkonium ChlorideIn Vitro

(2014) Mary M. Feng et al.   CURRENT EYE RESEARCH

Paternal Mitochondrial Destruction after Fertilization Is Mediated by a Common Endocytic and Autophagic Pathway in Drosophila

(2014) Yoav Politi et al.   DEVELOPMENTAL CELL

LC3 Binding to the Scaffolding Protein JIP1 Regulates Processive Dynein-Driven Transport of Autophagosomes

(2014) Meng-meng Fu et al.   DEVELOPMENTAL CELL

AMBRA1 Interplay with Cullin E3 Ubiquitin Ligases Regulates Autophagy Dynamics

(2014) Manuela Antonioli et al.   DEVELOPMENTAL CELL

Mitochondrial ER Contacts Are Crucial for Mitophagy in Yeast

(2014) Stefan Böckler et al.   DEVELOPMENTAL CELL

TRIM Proteins Regulate Autophagy and Can Target Autophagic Substrates by Direct Recognition

(2014) Michael A. Mandell et al.   DEVELOPMENTAL CELL

The C. elegans LC3 Acts Downstream of GABARAP to Degrade Autophagosomes by Interacting with the HOPS Subunit VPS39

(2014) Marion Manil-Ségalen et al.   DEVELOPMENTAL CELL

Involvement of Oxidative Stress–Induced DNA Damage, Endoplasmic Reticulum Stress, and Autophagy Deficits in the Decline of β-Cell Mass in Japanese Type 2 Diabetic Patients

(2014) Hiroki Mizukami et al.   DIABETES CARE

Autophagy in adipose tissue and the beta cell: implications for obesity and diabetes

(2014) Rinke Stienstra et al.   DIABETOLOGIA

Bulk RNA degradation by nitrogen starvation-induced autophagy in yeast

(2014) H. Huang et al.   EMBO JOURNAL

Defects in GABA metabolism affect selective autophagy pathways and are alleviated by mTOR inhibition

(2014) R. Lakhani et al.   EMBO Molecular Medicine

Hrr25 kinase promotes selective autophagy by phosphorylating the cargo receptor Atg19

(2014) T. Pfaffenwimmer et al.   EMBO REPORTS

Structural determinants in GABARAP required for the selective binding and recruitment of ALFY to LC3B-positive structures

(2014) A. H. Lystad et al.   EMBO REPORTS

PI3P phosphatase activity is required for autophagosome maturation and autolysosome formation

(2014) Y. Wu et al.   EMBO REPORTS

Raf/MEK/ERK can regulate cellular levels of LC3B and SQSTM1/p62 at expression levels

(2014) Jin-Hwan Kim et al.   EXPERIMENTAL CELL RESEARCH

Everolimus prolonged survival in transgenic mice with EGFR-driven lung tumors

(2014) Masayuki Yasugi et al.   EXPERIMENTAL CELL RESEARCH

Retinoid receptor signaling and autophagy in acute promyelocytic leukemia

(2014) Nina Orfali et al.   EXPERIMENTAL CELL RESEARCH

Autophagy in the eye: Implications for ocular cell health

(2014) Laura S. Frost et al.   EXPERIMENTAL EYE RESEARCH

Astroglial heme oxygenase-1 and the origin of corpora amylacea in aging and degenerating neural tissues

(2014) Wei Song et al.   EXPERIMENTAL NEUROLOGY

The necessity of and strategies for improving confidence in the accuracy of western blots

(2014) Rajeshwary Ghosh et al.   Expert Review of Proteomics

Regulation of autophagy: Modulation of the size and number of autophagosomes

(2014) Meiyan Jin et al.   FEBS LETTERS

Loss of Fig4 in both Schwann cells and motor neurons contributes to CMT4J neuropathy

(2014) Ilaria Vaccari et al.   HUMAN MOLECULAR GENETICS

(Poly)phenols protect from α-synuclein toxicity by reducing oxidative stress and promoting autophagy

(2014) Diana Macedo et al.   HUMAN MOLECULAR GENETICS

C9ORF72, implicated in amytrophic lateral sclerosis and frontotemporal dementia, regulates endosomal trafficking

(2014) Manal A. Farg et al.   HUMAN MOLECULAR GENETICS

TBC1D7Mutations are Associated with Intellectual Disability, Macrocrania, Patellar Dislocation, and Celiac Disease

(2014) Ali Abdullah Alfaiz et al.   HUMAN MUTATION

The Parasitophorous Vacuole Membrane of Toxoplasma gondii Is Targeted for Disruption by Ubiquitin-like Conjugation Systems of Autophagy

(2014) Jayoung Choi et al.   IMMUNITY

PPARβ/δ attenuates palmitate-induced endoplasmic reticulum stress and induces autophagic markers in human cardiac cells

(2014) Xavier Palomer et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Targeting γ-Herpesvirus 68 Bcl-2-mediated Down-regulation of Autophagy

(2014) Minfei Su et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Lysosomal Two-pore Channel Subtype 2 (TPC2) Regulates Skeletal Muscle Autophagic Signaling

(2014) Pei-Hui Lin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Interplay between Sumoylation and Phosphorylation for Protection against α-Synuclein Inclusions

(2014) Hedieh Shahpasandzadeh et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

p62 Plays a Protective Role in the Autophagic Degradation of Polyglutamine Protein Oligomers in Polyglutamine Disease Model Flies

(2014) Yuji Saitoh et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Decorin Induces Mitophagy in Breast Carcinoma Cells via Peroxisome Proliferator-activated Receptor γ Coactivator-1α (PGC-1α) and Mitostatin

(2014) Thomas Neill et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Endorepellin Evokes Autophagy in Endothelial Cells

(2014) Chiara Poluzzi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Acinus integrates AKT1 and subapoptotic caspase activities to regulate basal autophagy

(2014) Nilay Nandi et al.   JOURNAL OF CELL BIOLOGY

TheDrosophilaeffector caspase Dcp-1 regulates mitochondrial dynamics and autophagic flux via SesB

(2014) Lindsay DeVorkin et al.   JOURNAL OF CELL BIOLOGY

Peroxisomal Atg37 binds Atg30 or palmitoyl-CoA to regulate phagophore formation during pexophagy

(2014) Taras Y. Nazarko et al.   JOURNAL OF CELL BIOLOGY

Hrr25 triggers selective autophagy–related pathways by phosphorylating receptor proteins

(2014) Chikara Tanaka et al.   JOURNAL OF CELL BIOLOGY

A sterol-enriched vacuolar microdomain mediates stationary phase lipophagy in budding yeast

(2014) Chao-Wen Wang et al.   JOURNAL OF CELL BIOLOGY

CIP2A oncoprotein controls cell growth and autophagy through mTORC1 activation

(2014) Pietri Puustinen et al.   JOURNAL OF CELL BIOLOGY

Ubiquitylation by the Ltn1 E3 ligase protects 60S ribosomes from starvation-induced selective autophagy

(2014) Batool Ossareh-Nazari et al.   JOURNAL OF CELL BIOLOGY

A specific subset of E2 ubiquitin-conjugating enzymes regulate Parkin activation and mitophagy differently

(2014) F. C. Fiesel et al.   JOURNAL OF CELL SCIENCE

The ubiquitin-conjugating enzymes UBE2N, UBE2L3 and UBE2D2/3 are essential for Parkin-dependent mitophagy

(2014) Sven Geisler et al.   JOURNAL OF CELL SCIENCE

ER-phagy mediates selective degradation of endoplasmic reticulum independently of the core autophagy machinery

(2014) S. Schuck et al.   JOURNAL OF CELL SCIENCE

TAK1-mediated autophagy and fatty acid oxidation prevent hepatosteatosis and tumorigenesis

(2014) Sayaka Inokuchi-Shimizu et al.   JOURNAL OF CLINICAL INVESTIGATION

Amyloidogenic peptide oligomer accumulation in autophagy-deficient β cells induces diabetes

(2014) Jinyoung Kim et al.   JOURNAL OF CLINICAL INVESTIGATION

Human IAPP–induced pancreatic β cell toxicity and its regulation by autophagy

(2014) Nayumi Shigihara et al.   JOURNAL OF CLINICAL INVESTIGATION

Autophagy defends pancreatic β cells from human islet amyloid polypeptide-induced toxicity

(2014) Jacqueline F. Rivera et al.   JOURNAL OF CLINICAL INVESTIGATION

Autophagy-regulating TP53INP2 mediates muscle wasting and is repressed in diabetes

(2014) David Sala et al.   JOURNAL OF CLINICAL INVESTIGATION

Atg7 Enhances Host Defense against Infection via Downregulation of Superoxide but Upregulation of Nitric Oxide

(2014) Xuefeng Li et al.   JOURNAL OF IMMUNOLOGY

Role of Mouse and Human Autophagy Proteins in IFN- -Induced Cell-Autonomous Responses against Toxoplasma gondii

(2014) J. Ohshima et al.   JOURNAL OF IMMUNOLOGY

Editorial: Gigantism: a new way to prolong neutrophil life

(2014) Giorgio Berton   JOURNAL OF LEUKOCYTE BIOLOGY

The development of giant phagocytes in long-term neutrophil cultures

(2014) Larissa Dyugovskaya et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Identification of an Atg8-Atg3 Protein–Protein Interaction Inhibitor from the Medicines for Malaria Venture Malaria Box Active in Blood and Liver Stage Plasmodium falciparum Parasites

(2014) Adelaide U.P. Hain et al.   JOURNAL OF MEDICINAL CHEMISTRY

Corynoxine, a Natural Autophagy Enhancer, Promotes the Clearance of Alpha-Synuclein via Akt/mTOR Pathway

(2014) Lei-Lei Chen et al.   Journal of Neuroimmune Pharmacology

Neutrophil extracellular traps promote differentiation and function of fibroblasts

(2014) Akrivi Chrysanthopoulou et al.   JOURNAL OF PATHOLOGY

Activated platelets present high mobility group box 1 to neutrophils, inducing autophagy and promoting the extrusion of neutrophil extracellular traps

(2014) N. Maugeri et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Disruption of autophagy by the histone deacetylase inhibitor MGCD0103 and its therapeutic implication in B-cell chronic lymphocytic leukemia

(2014) V El-Khoury et al.   LEUKEMIA

Assays to monitor autophagy in Drosophila

(2014) Caroline Mauvezin et al.   METHODS

Autophagic flux determines cell death and survival in response to Apo2L/TRAIL (dulanermin)

(2014) Kamini Singh et al.   Molecular Cancer

Early Steps in Autophagy Depend on Direct Phosphorylation of Atg9 by the Atg1 Kinase

(2014) Daniel Papinski et al.   MOLECULAR CELL

Regulation of Autophagy by Cytosolic Acetyl-Coenzyme A

(2014) Guillermo Mariño et al.   MOLECULAR CELL

Ral and Rheb GTPase Activating Proteins Integrate mTOR and GTPase Signaling in Aging, Autophagy, and Tumor Cell Invasion

(2014) Timothy D. Martin et al.   MOLECULAR CELL

A Revised Assay for Monitoring Autophagic Flux in Arabidopsis thaliana Reveals Involvement of AUTOPHAGY-RELATED9 in Autophagy

(2014) Kwang Deok Shin et al.   MOLECULES AND CELLS

Caspase-11 activation requires lysis of pathogen-containing vacuoles by IFN-induced GTPases

(2014) Etienne Meunier et al.   NATURE

Selective VPS34 inhibitor blocks autophagy and uncovers a role for NCOA4 in ferritin degradation and iron homeostasis in vivo

(2014) William E. Dowdle et al.   NATURE CELL BIOLOGY

AMBRA1 links autophagy to cell proliferation and tumorigenesis by promoting c-Myc dephosphorylation and degradation

(2014) Valentina Cianfanelli et al.   NATURE CELL BIOLOGY

A highly potent and selective Vps34 inhibitor alters vesicle trafficking and autophagy

(2014) Baptiste Ronan et al.   Nature Chemical Biology

Caloric restriction mimetics: towards a molecular definition

(2014) Frank Madeo et al.   NATURE REVIEWS DRUG DISCOVERY

Autophagy regulates amyotrophic lateral sclerosis-linked fused in sarcoma-positive stress granules in neurons

(2014) Hyun-Hee Ryu et al.   NEUROBIOLOGY OF AGING

Dysregulated expression of lipid storage and membrane dynamics factors in Tia1 knockout mouse nervous tissue

(2014) Melanie Vanessa Heck et al.   NEUROGENETICS

Novel CLN3 mutation causing autophagic vacuolar myopathy

(2014) A. Cortese et al.   NEUROLOGY

201st ENMC International Workshop: Autophagy in muscular dystrophies – Translational approach, 1–3 November 2013, Bussum, The Netherlands

(2014) Luciano Merlini et al.   NEUROMUSCULAR DISORDERS

Dual inhibition of REV-ERBβ and autophagy as a novel pharmacological approach to induce cytotoxicity in cancer cells

(2014) C De Mei et al.   ONCOGENE

ER stress, autophagy and immunogenic cell death in photodynamic therapy-induced anti-cancer immune responses

(2014) Abhishek D. Garg et al.   PHOTOCHEMICAL & PHOTOBIOLOGICAL SCIENCES

Arabidopsis ATG8-INTERACTING PROTEIN1 Is Involved in Autophagy-Dependent Vesicular Trafficking of Plastid Proteins to the Vacuole

(2014) S. Michaeli et al.   PLANT CELL

Oxidative Stress Contributes to Autophagy Induction in Response to Endoplasmic Reticulum Stress in Chlamydomonas reinhardtii

(2014) M. Perez-Martin et al.   PLANT PHYSIOLOGY

Trehalose Reverses Cell Malfunction in Fibroblasts from Normal and Huntington's Disease Patients Caused by Proteosome Inhibition

(2014) Maria Angeles Fernandez-Estevez et al.   PLoS One

Gene Expression Profiling in Tibial Muscular Dystrophy Reveals Unfolded Protein Response and Altered Autophagy

(2014) Mark Screen et al.   PLoS One

HRES-1/Rab4 Promotes the Formation of LC3+ Autophagosomes and the Accumulation of Mitochondria during Autophagy

(2014) Gergely Talaber et al.   PLoS One

The E2-Like Conjugation Enzyme Atg3 Promotes Binding of IRG and Gbp Proteins to Chlamydia- and Toxoplasma-Containing Vacuoles and Host Resistance

(2014) Arun K. Haldar et al.   PLoS One

Novel Quantitative Autophagy Analysis by Organelle Flow Cytometry after Cell Sonication

(2014) Michael Degtyarev et al.   PLoS One

Hypoxia Enhances the Antiglioma Cytotoxicity of B10, a Glycosylated Derivative of Betulinic Acid

(2014) Sebastian Fischer et al.   PLoS One

Loss of PINK1 Impairs Stress-Induced Autophagy and Cell Survival

(2014) Dajana Parganlija et al.   PLoS One

Autophagy in Trypanosoma brucei: Amino Acid Requirement and Regulation during Different Growth Phases

(2014) Remo S. Schmidt et al.   PLoS One

Zebrafish ambra1a and ambra1b Knockdown Impairs Skeletal Muscle Development

(2014) Tatjana Skobo et al.   PLoS One

Autophagy Inhibitor LRPPRC Suppresses Mitophagy through Interaction with Mitophagy Initiator Parkin

(2014) Jing Zou et al.   PLoS One

Characterization of the Autophagy Marker Protein Atg8 Reveals Atypical Features of Autophagy in Plasmodium falciparum

(2014) Rahul Navale et al.   PLoS One

Genome-wide RNAi screen identifies the Parkinson disease GWAS risk locus SREBF1 as a regulator of mitophagy

(2014) R. M. Ivatt et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Transcellular degradation of axonal mitochondria

(2014) Chung-ha O. Davis et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Prosurvival Bcl-2 family members affect autophagy only indirectly, by inhibiting Bax and Bak

(2014) L. M. Lindqvist et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Aberrant calcium signaling by transglutaminase-mediated posttranslational modification of inositol 1,4,5-trisphosphate receptors

(2014) K. Hamada et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

BAT3 modulates p300-dependent acetylation of p53 and autophagy-related protein 7 (ATG7) during autophagy

(2014) S. Sebti et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

TOR complex 2-Ypk1 signaling is an essential positive regulator of the general amino acid control response and autophagy

(2014) A. Vlahakis et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

UVRAG is required for virus entry through combinatorial interaction with the class C-Vps complex and SNAREs

(2014) S. D. Pirooz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hepatitis C virus triggers mitochondrial fission and attenuates apoptosis to promote viral persistence

(2014) S.-J. Kim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Arginine starvation-associated atypical cellular death involves mitochondrial dysfunction, nuclear DNA leakage, and chromatin autophagy

(2014) Chun A. Changou et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The structural and functional signatures of proteins that undergo multiple events of post-translational modification

(2014) Vikas Pejaver et al.   PROTEIN SCIENCE

Vmp1 Regulates PtdIns3P Signaling During Autophagosome Formation inDictyostelium discoideum

(2014) Javier Calvo-Garrido et al.   TRAFFIC

Mpl Traffics to the Cell Surface Through Conventional and Unconventional Routes

(2014) Cédric Cleyrat et al.   TRAFFIC

Parkin and PINK1: much more than mitophagy

(2014) Leslie A. Scarffe et al.   TRENDS IN NEUROSCIENCES

Expression analysis of autophagy-related genes in the hard tick Haemaphysalis longicornis

(2014) Rika Umemiya-Shirafuji et al.   VETERINARY PARASITOLOGY

Impaired autophagic flux is associated with increased endoplasmic reticulum stress during the development of NAFLD

(2014) Á González-Rodríguez et al.   Cell Death & Disease

Role of alpha-synuclein in autophagy modulation of primary human T lymphocytes

(2014) T Colasanti et al.   Cell Death & Disease

Betulinic acid-induced mitochondria-dependent cell death is counterbalanced by an autophagic salvage response

(2014) L Potze et al.   Cell Death & Disease

Regulation of autophagy by polyphenolic compounds as a potential therapeutic strategy for cancer

(2014) N Hasima et al.   Cell Death & Disease

PICALM modulates autophagy activity and tau accumulation

(2014) Kevin Moreau et al.   Nature Communications

A non-conserved miRNA regulates lysosomal function and impacts on a human lysosomal storage disorder

(2014) Lisa B. Frankel et al.   Nature Communications

ATG5 defines a phagophore domain connected to the endoplasmic reticulum during autophagosome formation in plants

(2014) Romain Le Bars et al.   Nature Communications

Functional Genomics Evidence Unearths New Moonlighting Roles of Outer Ring Coat Nucleoporins

(2014) Katerina R. Katsani et al.   Scientific Reports

A retrospective cohort study identifying the principal pathological features useful in the diagnosis of inclusion body myositis

(2014) Stefen Brady et al.   BMJ Open

κB-Ras Proteins Regulate Both NF-κB-Dependent Inflammation and Ral-Dependent Proliferation

(2014) Andrea Oeckinghaus et al.   Cell Reports

Antagonism of Tumoral Prolactin Receptor Promotes Autophagy-Related Cell Death

(2014) Yunfei Wen et al.   Cell Reports

Morphological and bioenergetic demands underlying the mitophagy in post-mitotic neurons: the pink–parkin pathway

(2014) Giuseppina Amadoro et al.   Frontiers in Aging Neuroscience

Aberrant Autolysosomal Regulation Is Linked to The Induction of Embryonic Senescence: Differential Roles of Beclin 1 and p53 in Vertebrate Spns1 Deficiency

(2014) Tomoyuki Sasaki et al.   PLoS Genetics

Association of FKBP51 with Priming of Autophagy Pathways and Mediation of Antidepressant Treatment Response: Evidence in Cells, Mice, and Humans

(2014) Nils C. Gassen et al.   PLOS MEDICINE

A Simple Method to Estimate the Number of Autophagic Elements by Electron Microscopic Morphometry in Real Cellular Dimensions

(2014) Attila L. Kovács   Biomed Research International

A Molecular View of Autophagy in Lepidoptera

(2014) Davide Romanelli et al.   Biomed Research International

ROS-dependent prostate apoptosis response-4 (Par-4) up-regulation and ceramide generation are the prime signaling events associated with curcumin-induced autophagic cell death in human malignant glioma

(2014) Faisal Thayyullathil et al.   FEBS Open Bio

Variants of mitochondrial autophagy: Types 1 and 2 mitophagy and micromitophagy (Type 3)

(2014) John J. Lemasters   Redox Biology

mTOR-dependent abnormalities in autophagy characterize human malformations of cortical development: evidence from focal cortical dysplasia and tuberous sclerosis

(2013) Shireena A. Yasin et al.   ACTA NEUROPATHOLOGICA

Autophagy is altered in skeletal and cardiac muscle of spontaneously hypertensive rats

(2013) D. Bloemberg et al.   Acta Physiologica

Reduced mammalian target of rapamycin activity facilitates mitochondrial retrograde signaling and increases life span in normal human fibroblasts

(2013) Chad Lerner et al.   AGING CELL

Autophagy mediates caloric restriction-induced lifespan extension inArabidopsis

(2013) Elena A. Minina et al.   AGING CELL

Balance between autophagic pathways preserves retinal homeostasis

(2013) Natalia Rodríguez-Muela et al.   AGING CELL

7-Ketocholesterol Induces Autophagy in Vascular Smooth Muscle Cells through Nox4 and Atg4B

(2013) Chaoyong He et al.   AMERICAN JOURNAL OF PATHOLOGY

Autophagic Degradation Contributes to Muscle Wasting in Cancer Cachexia

(2013) Fabio Penna et al.   AMERICAN JOURNAL OF PATHOLOGY

Higher activation of autophagy in skeletal muscle of mice during endurance exercise in the fasted state

(2013) Cécile Jamart et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Impairment of autophagy decreases ventilator-induced lung injury by blockade of the NF-κB pathway

(2013) Inés López-Alonso et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

LC3 and p62 as Diagnostic Markers of Drug-induced Autophagic Vacuolar Cardiomyopathy

(2013) Brianne H. Daniels et al.   AMERICAN JOURNAL OF SURGICAL PATHOLOGY

HRES-1/Rab4-mediated depletion of Drp1 impairs mitochondrial homeostasis and represents a target for treatment in SLE

(2013) Tiffany N Caza et al.   ANNALS OF THE RHEUMATIC DISEASES

Self-eating to grow and kill: autophagy in filamentous ascomycetes

(2013) Oliver Voigt et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Role of autophagy, SQSTM1, SH3GLB1, and TRIM63 in the turnover of nicotinic acetylcholine receptors

(2013) Muzamil Majid Khan et al.   Autophagy

20-hydroxyecdysone upregulatesAtggenes to induce autophagy in the Bombyx fat body

(2013) Ling Tian et al.   Autophagy

Autophagy receptor CALCOCO2/NDP52 takes center stage in Crohn disease

(2013) Andreas Till et al.   Autophagy

ROS-induced autophagy in cancer cells assists in evasion from determinants of immunogenic cell death

(2013) Abhishek D. Garg et al.   Autophagy

Connect the dots

(2013) Yifei Li et al.   Autophagy

A conserved domain in exon 2 coding for the human and murine ARF tumor suppressor protein is required for autophagy induction

(2013) Anna Budina-Kolomets et al.   Autophagy

Estimating the size and number of autophagic bodies by electron microscopy

(2013) Steven K Backues et al.   Autophagy

Spread of neuronal degeneration in a dopaminergic,Lrrk-G2019Smodel of Parkinson disease

(2013) Samantha J. Hindle et al.   Autophagy

A bird’s-eye view of autophagy

(2013) Petro Starokadomskyy et al.   Autophagy

The emerging role of acetylation in the regulation of autophagy

(2013) Ágnes Bánréti et al.   Autophagy

The twoC. elegansATG-16 homologs have partially redundant functions in the basal autophagy pathway

(2013) Hui Zhang et al.   Autophagy

The role of Atg29 phosphorylation in PAS assembly

(2013) Kai Mao et al.   Autophagy

Discovery of a novel type of autophagy targeting RNA

(2013) Yuuki Fujiwara et al.   Autophagy

Ats-1

(2013) Hua Niu et al.   Autophagy

TECPR2

(2013) Danit Oz-Levi et al.   Autophagy

Cutting a fine figure

(2013) John Milton Lucocq et al.   Autophagy

Autophagy

(2013) Neng-Yu Lin et al.   Autophagy

Structural characterization of theSaccharomyces cerevisiaeautophagy regulatory complex Atg17-Atg31-Atg29

(2013) Leon H Chew et al.   Autophagy

Autophagy and formation of tubulovesicular autophagosomes provide a barrier against nonviral gene delivery

(2013) Rebecca Roberts et al.   Autophagy

The variability of autophagy and cell death susceptibility

(2013) Ben Loos et al.   Autophagy

MTORC1 determines autophagy through ULK1 regulation in skeletal muscle

(2013) Perrine Castets et al.   Autophagy

Linkage of autophagy to fungal development, lipid storage and virulence inMetarhizium robertsii

(2013) Zhibing Duan et al.   Autophagy

Live-cell imaging ofAspergillus nidulansautophagy

(2013) Mario Pinar et al.   Autophagy

Live imaging and single-cell analysis reveal differential dynamics of autophagy and apoptosis

(2013) Yangqing Xu et al.   Autophagy

Autophagy and phagocytosis converge for better vision

(2013) Thomas A Ferguson et al.   Autophagy

HMGB1 is involved in autophagy inhibition caused by SNCA/α-synuclein overexpression

(2013) Ju-Xian Song et al.   Autophagy

Atg24-assisted mitophagy in the foot cells is necessary for proper asexual differentiation inMagnaporthe oryzae

(2013) Yunlong He et al.   Autophagy

Regulation of ATG8 membrane association by ATG4 in the parasitic protistToxoplasma gondii

(2013) Marie A. Kong-Hap et al.   Autophagy

Plasmodium falciparumATG8 implicated in both autophagy and apicoplast formation

(2013) Andrew M Tomlins et al.   Autophagy

Drosophila Fip200 is an essential regulator of autophagy that attenuates both growth and aging

(2013) Myungjin Kim et al.   Autophagy

Trehalose delays the progression of amyotrophic lateral sclerosis by enhancing autophagy in motoneurons

(2013) Karen Castillo et al.   Autophagy

Polyamine depletion inhibits the autophagic response modulatingTrypanosoma cruziinfectivity

(2013) María C. Vanrell et al.   Autophagy

The protonophore CCCP interferes with lysosomal degradation of autophagic cargo in yeast and mammalian cells

(2013) Benjamin S Padman et al.   Autophagy

Ambra1knockdown in zebrafish leads to incomplete development due to severe defects in organogenesis

(2013) Francesca Benato et al.   Autophagy

Ultrastructure of autophagy in plant cells

(2013) Wouter G van Doorn et al.   Autophagy

Modulation of intracellular calcium homeostasis blocks autophagosome formation

(2013) Nikolai Engedal et al.   Autophagy

The TOMM machinery is a molecular switch in PINK1 and PARK2/PARKIN-dependent mitochondrial clearance

(2013) Giulia Bertolin et al.   Autophagy

The accumulation of misfolded proteins in the mitochondrial matrix is sensed by PINK1 to induce PARK2/Parkin-mediated mitophagy of polarized mitochondria

(2013) Seok Min Jin et al.   Autophagy

Direct uptake and degradation of DNA by lysosomes

(2013) Yuuki Fujiwara et al.   Autophagy

Functions of autophagy in normal and diseased liver

(2013) Mark J. Czaja et al.   Autophagy

Novel tamoxifen derivative Ridaifen-B induces Bcl-2 independent autophagy without estrogen receptor involvement

(2013) Yukitoshi Nagahara et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Induction of oxiapoptophagy, a mixed mode of cell death associated with oxidative stress, apoptosis and autophagy, on 7-ketocholesterol-treated 158N murine oligodendrocytes: Impairment by α-tocopherol

(2013) Thomas Nury et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Mitochondrion-associated protein LRPPRC suppresses the initiation of basal levels of autophagy via enhancing Bcl-2 stability

(2013) Jing Zou et al.   BIOCHEMICAL JOURNAL

miR-205 impairs the autophagic flux and enhances cisplatin cytotoxicity in castration-resistant prostate cancer cells

(2013) Marzia Pennati et al.   BIOCHEMICAL PHARMACOLOGY

The pseudokinase tribbles homologue-3 plays a crucial role in cannabinoid anticancer action

(2013) María Salazar et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Autophagy paradox and ceramide

(2013) Wenhui Jiang et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Rapid screening of potential autophagic inductor agents using mammalian cell lines

(2013) Waleska K. Martins et al.   Biotechnology Journal

Defective autophagy in spastizin mutated patients with hereditary spastic paraparesis type 15

(2013) Chiara Vantaggiato et al.   BRAIN

Pazopanib and sunitinib trigger autophagic and non-autophagic death of bladder tumour cells

(2013) M Santoni et al.   BRITISH JOURNAL OF CANCER

LITAF, a BCL6 target gene, regulates autophagy in mature B-cell lymphomas

(2013) Cristina Bertolo et al.   BRITISH JOURNAL OF HAEMATOLOGY

Autophagy and enhanced chemosensitivity in experimental pancreatic cancers induced by noninvasive radiofrequency field treatment

(2013) Nadezhda V. Koshkina et al.   CANCER

Chloroquine in Cancer Therapy: A Double-Edged Sword of Autophagy

(2013) T. Kimura et al.   CANCER RESEARCH

Beclin 2 Functions in Autophagy, Degradation of G Protein-Coupled Receptors, and Metabolism

(2013) Congcong He et al.   CELL

Eukaryotic Stress Granules Are Cleared by Autophagy and Cdc48/VCP Function

(2013) J. Ross Buchan et al.   CELL

EGFR-Mediated Beclin 1 Phosphorylation in Autophagy Suppression, Tumor Progression, and Tumor Chemoresistance

(2013) Yongjie Wei et al.   CELL

Differential Regulation of Distinct Vps34 Complexes by AMPK in Nutrient Stress and Autophagy

(2013) Joungmok Kim et al.   CELL

mTOR Regulates Lysosomal ATP-Sensitive Two-Pore Na+ Channels to Adapt to Metabolic State

(2013) Chunlei Cang et al.   CELL

Macromitophagy, neutral lipids synthesis, and peroxisomal fatty acid oxidation protect yeast from “liponecrosis”, a previously unknown form of programmed cell death

(2013) Sara Sheibani et al.   CELL CYCLE

Resilience of death: intrinsic disorder in proteins involved in the programmed cell death

(2013) Z Peng et al.   CELL DEATH AND DIFFERENTIATION

Autophagy is required for zebrafish caudal fin regeneration

(2013) M Varga et al.   CELL DEATH AND DIFFERENTIATION

Danger signalling during cancer cell death: origins, plasticity and regulation

(2013) A D Garg et al.   CELL DEATH AND DIFFERENTIATION

A neuroprotective phase precedes striatal degeneration upon nucleolar stress

(2013) G Kreiner et al.   CELL DEATH AND DIFFERENTIATION

The Globally Disseminated M1T1 Clone of Group A Streptococcus Evades Autophagy for Intracellular Replication

(2013) Timothy C. Barnett et al.   Cell Host & Microbe

Sestrins Orchestrate Cellular Metabolism to Attenuate Aging

(2013) Jun Hee Lee et al.   Cell Metabolism

Sustained Activation of mTORC1 in Skeletal Muscle Inhibits Constitutive and Starvation-Induced Autophagy and Causes a Severe, Late-Onset Myopathy

(2013) Perrine Castets et al.   Cell Metabolism

Mitochondria and Quality Control Defects in a Mouse Model of Gaucher Disease—Links to Parkinson’s Disease

(2013) Laura D. Osellame et al.   Cell Metabolism

Rheb Regulates Mitophagy Induced by Mitochondrial Energetic Status

(2013) Su Melser et al.   Cell Metabolism

HDAC6 mediates the acetylation of TRIM50

(2013) Carmela Fusco et al.   CELLULAR SIGNALLING

Cellular Mechanotransduction Relies on Tension-Induced and Chaperone-Assisted Autophagy

(2013) Anna Ulbricht et al.   CURRENT BIOLOGY

Targeting miR-21 Induces Autophagy and Chemosensitivity of Leukemia Cells

(2013) Hugo Seca et al.   CURRENT DRUG TARGETS

A179L, a New Viral Bcl2 Homolog Targeting Beclin 1 Autophagy Related Protein

(2013) B. Hernaez et al.   CURRENT MOLECULAR MEDICINE

Noncanonical autophagy: one small step for LC3, one giant leap for immunity

(2013) Payal Mehta et al.   CURRENT OPINION IN IMMUNOLOGY

Intrinsic Disorder-based Protein Interactions and their Modulators

(2013) Vladimir N. Uversky   CURRENT PHARMACEUTICAL DESIGN

Inducers of immunogenic cancer cell death

(2013) Aleksandra M. Dudek et al.   CYTOKINE & GROWTH FACTOR REVIEWS

Atg6 is required for multiple vesicle trafficking pathways and hematopoiesis in Drosophila

(2013) B. V. Shravage et al.   DEVELOPMENT

The Scaffold Protein Atg11 Recruits Fission Machinery to Drive Selective Mitochondria Degradation by Autophagy

(2013) Kai Mao et al.   DEVELOPMENTAL CELL

RNA Sequencing Identifies Dysregulation of the Human Pancreatic Islet Transcriptome by the Saturated Fatty Acid Palmitate

(2013) Miriam Cnop et al.   DIABETES

“Stainomics”: Identification of mitotracker labeled proteins in mammalian cells

(2013) Hongjuan Dong et al.   ELECTROPHORESIS

Autophagy proteins control goblet cell function by potentiating reactive oxygen species production

(2013) Khushbu K Patel et al.   EMBO JOURNAL

TMEM59 defines a novel ATG16L1-binding motif that promotes local activation of LC3

(2013) Emilio Boada-Romero et al.   EMBO JOURNAL

Autolysosomal β-catenin degradation regulates Wnt-autophagy-p62 crosstalk

(2013) Katy J Petherick et al.   EMBO JOURNAL

Autophagy sequesters damaged lysosomes to control lysosomal biogenesis and kidney injury

(2013) Ikuko Maejima et al.   EMBO JOURNAL

Autophagy modulates miRNA-mediated gene silencing and selectively degrades AIN-1/GW182 in C. elegans

(2013) Peipei Zhang et al.   EMBO REPORTS

Species-specific impact of the autophagy machinery on Chikungunya virus infection

(2013) Delphine Judith et al.   EMBO REPORTS

Non-autophagic roles of autophagy-related proteins

(2013) Suresh Subramani et al.   EMBO REPORTS

Rab12 regulates mTORC1 activity and autophagy through controlling the degradation of amino-acid transporter PAT4

(2013) Takahide Matsui et al.   EMBO REPORTS

Loss of iron triggers PINK1/Parkin-independent mitophagy

(2013) George F G Allen et al.   EMBO REPORTS

Autophagy failure in Alzheimer's disease and the role of defective lysosomal acidification

(2013) Devin M. Wolfe et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Identification of a small molecule that induces ATG5-and-cathepsin-l-dependent cell death and modulates polyglutamine toxicity

(2013) Hemant Varma et al.   EXPERIMENTAL CELL RESEARCH

Weakness, SR function and stress in gastrocnemius muscles of aged male rats

(2013) David W. Russ et al.   EXPERIMENTAL GERONTOLOGY

Induction of sestrin2 as an endogenous protective mechanism against amyloid beta-peptide neurotoxicity in primary cortical culture

(2013) Yueh-Sheng Chen et al.   EXPERIMENTAL NEUROLOGY

Lack of myotubularin (MTM1) leads to muscle hypotrophy through unbalanced regulation of the autophagy and ubiquitin-proteasome pathways

(2013) Lama Al-Qusairi et al.   FASEB JOURNAL

Stress granules in neurodegeneration - lessons learnt from TAR DNA binding protein of 43 kDa and fused in sarcoma

(2013) Eva Bentmann et al.   FEBS Journal

Crohn's Disease–Associated Adherent Invasive Escherichia coli Modulate Levels of microRNAs in Intestinal Epithelial Cells to Reduce Autophagy

(2013) Hang Thi Thu Nguyen et al.   GASTROENTEROLOGY

Exploiting the bad eating habits of Ras-driven cancers

(2013) E. White   GENES & DEVELOPMENT

Genome-wide association study of Crohn's disease in Koreans revealed three new susceptibility loci and common attributes of genetic susceptibility across ethnic populations

(2013) Suk-Kyun Yang et al.   GUT

Autophagy suppresses tumorigenesis of hepatitis B virus-associated hepatocellular carcinoma through degradation of microRNA-224

(2013) Sheng-Hui Lan et al.   HEPATOLOGY

Caffeine stimulates hepatic lipid metabolism by the autophagy-lysosomal pathway in mice

(2013) Rohit A. Sinha et al.   HEPATOLOGY

Next generation sequencing-based molecular diagnosis of retinitis pigmentosa: identification of a novel genotype-phenotype correlation and clinical refinements

(2013) Feng Wang et al.   HUMAN GENETICS

IGF-1 receptor antagonism inhibits autophagy

(2013) Maurizio Renna et al.   HUMAN MOLECULAR GENETICS

Proof of myocardial autophagy by combining antigen retrieval and the avidin–biotin peroxidase complex method

(2013) Tsunenori Saito et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

From Identification to Characterization of the Multiple Sclerosis Susceptibility Gene CLEC16A

(2013) Tone Berge et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Lacritin Rescues Stressed Epithelia via Rapid Forkhead Box O3 (FOXO3)-associated Autophagy That Restores Metabolism

(2013) Ningning Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Suppression of Lysosome Function Induces Autophagy via a Feedback Down-regulation of MTOR Complex 1 (MTORC1) Activity

(2013) Min Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Atg38 is required for autophagy-specific phosphatidylinositol 3-kinase complex integrity

(2013) Yasuhiro Araki et al.   JOURNAL OF CELL BIOLOGY

Lipid droplet breakdown requires Dynamin 2 for vesiculation of autolysosomal tubules in hepatocytes

(2013) Ryan J. Schulze et al.   JOURNAL OF CELL BIOLOGY

Autophagy and metacaspase determine the mode of cell death in plants

(2013) Elena A. Minina et al.   JOURNAL OF CELL BIOLOGY

The scaffold protein EPG-7 links cargo–receptor complexes with the autophagic assembly machinery

(2013) Long Lin et al.   JOURNAL OF CELL BIOLOGY

Membrane remodeling by the PX-BAR protein SNX18 promotes autophagosome formation

(2013) Helene Knævelsrud et al.   JOURNAL OF CELL BIOLOGY

Recruitment of folliculin to lysosomes supports the amino acid–dependent activation of Rag GTPases

(2013) Constance S. Petit et al.   JOURNAL OF CELL BIOLOGY

Autophagosomal Syntaxin17-dependent lysosomal degradation maintains neuronal function inDrosophila

(2013) Szabolcs Takáts et al.   JOURNAL OF CELL BIOLOGY

Regulation of mTORC1 and its impact on gene expression at a glance

(2013) M. Laplante et al.   JOURNAL OF CELL SCIENCE

Restricted mitochondrial protein acetylation initiates mitochondrial autophagy

(2013) B. R. Webster et al.   JOURNAL OF CELL SCIENCE

Alternative fates of newly formed PrPSc upon prion conversion on the plasma membrane

(2013) R. Goold et al.   JOURNAL OF CELL SCIENCE

CORVET and HOPS tethering complexes - coordinators of endosome and lysosome fusion

(2013) H. J. k. Balderhaar et al.   JOURNAL OF CELL SCIENCE

Misregulation of autophagy and protein degradation systems in myopathies and muscular dystrophies

(2013) M. Sandri et al.   JOURNAL OF CELL SCIENCE

The LC3 interactome at a glance

(2013) P. Wild et al.   JOURNAL OF CELL SCIENCE

Synergistic Cooperation Between Sunitinib and Cisplatin Promotes Apoptotic Cell Death in Human Medullary Thyroid Cancer

(2013) Alessia Lopergolo et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Novel features of Brassica napus embryogenic microspores revealed by high pressure freezing and freeze substitution: evidence for massive autophagy and excretion-based cytoplasmic cleaning

(2013) Patricia Corral-Martínez et al.   JOURNAL OF EXPERIMENTAL BOTANY

Autophagy Induction by SIRT6 through Attenuation of Insulin-like Growth Factor Signaling Is Involved in the Regulation of Human Bronchial Epithelial Cell Senescence

(2013) N. Takasaka et al.   JOURNAL OF IMMUNOLOGY

Autophagy and Viruses: Adversaries or Allies?

(2013) Xiaonan Dong et al.   Journal of Innate Immunity

Secretory versus Degradative Autophagy: Unconventional Secretion of Inflammatory Mediators

(2013) Shanya Jiang et al.   Journal of Innate Immunity

Autophagy Is Induced by UVA and Promotes Removal of Oxidized Phospholipids and Protein Aggregates in Epidermal Keratinocytes

(2013) Yi Zhao et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Disruption of TBC1D7, a subunit of the TSC1-TSC2 protein complex, in intellectual disability and megalencephaly

(2013) José-Mario Capo-Chichi et al.   JOURNAL OF MEDICAL GENETICS

Deficiency of p62/Sequestosome 1 Causes Hyperphagia Due to Leptin Resistance in the Brain

(2013) H. Harada et al.   JOURNAL OF NEUROSCIENCE

Regulated forms of cell death are induced by the photodynamic action of the fluorogenic substrate, Hypocrellin B-acetate

(2013) Giada Santin et al.   JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY

Activation of the Homeostatic Intracellular Repair Response During Cardiac Surgery

(2013) Salik M. Jahania et al.   JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS

mVps34 Deletion in Podocytes Causes Glomerulosclerosis by Disrupting Intracellular Vesicle Trafficking

(2013) J. Chen et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Autophagy gene fingerprint in human ischemia and reperfusion

(2013) Krishna K. Singh et al.   JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY

A novel mouse model of nonalcoholic steatohepatitis with significant insulin resistance

(2013) Yuriko Adkins et al.   LABORATORY INVESTIGATION

Histone deacetylase inhibitors induce apoptosis in myeloid leukemia by suppressing autophagy

(2013) M V Stankov et al.   LEUKEMIA

Sea urchin embryos exposed to cadmium as an experimental model for studying the relationship between autophagy and apoptosis

(2013) R. Chiarelli et al.   MARINE ENVIRONMENTAL RESEARCH

Regulation of mitophagy by the Gp78 E3 ubiquitin ligase

(2013) Min Fu et al.   MOLECULAR BIOLOGY OF THE CELL

Lipid droplet autophagy in the yeast Saccharomyces cerevisiae

(2013) Tim van Zutphen et al.   MOLECULAR BIOLOGY OF THE CELL

Syntaxin 13, a Genetic Modifier of Mutant CHMP2B in Frontotemporal Dementia, Is Required for Autophagosome Maturation

(2013) Yubing Lu et al.   MOLECULAR CELL

Arginine Methylation Modulates Autophagic Degradation of PGL Granules in C. elegans

(2013) Sihui Li et al.   MOLECULAR CELL

The Folliculin Tumor Suppressor Is a GAP for the RagC/D GTPases That Signal Amino Acid Levels to mTORC1

(2013) Zhi-Yang Tsun et al.   MOLECULAR CELL

ZKSCAN3 Is a Master Transcriptional Repressor of Autophagy

(2013) Santosh Chauhan et al.   MOLECULAR CELL

Autophagy has a key role in the pathophysiology of schizophrenia

(2013) A Merenlender-Wagner et al.   MOLECULAR PSYCHIATRY

The toxicity of antiprion antibodies is mediated by the flexible tail of the prion protein

(2013) Tiziana Sonati et al.   NATURE

Autophagosomes form at ER–mitochondria contact sites

(2013) Maho Hamasaki et al.   NATURE

Identification of a candidate therapeutic autophagy-inducing peptide

(2013) Sanae Shoji-Kawata et al.   NATURE

Preventing lysosomal fat indigestion

(2013) Ana Maria Cuervo   NATURE CELL BIOLOGY

Uba1 functions in Atg7- and Atg3-independent autophagy

(2013) Tsun-Kai Chang et al.   NATURE CELL BIOLOGY

TFEB controls cellular lipid metabolism through a starvation-induced autoregulatory loop

(2013) Carmine Settembre et al.   NATURE CELL BIOLOGY

MXL-3 and HLH-30 transcriptionally link lipolysis and autophagy to nutrient availability

(2013) Eyleen J. O’Rourke et al.   NATURE CELL BIOLOGY

A tuberous sclerosis complex signalling node at the peroxisome regulates mTORC1 and autophagy in response to ROS

(2013) Jiangwei Zhang et al.   NATURE CELL BIOLOGY

Cardiolipin externalization to the outer mitochondrial membrane acts as an elimination signal for mitophagy in neuronal cells

(2013) Charleen T. Chu et al.   NATURE CELL BIOLOGY

mTOR inhibits autophagy by controlling ULK1 ubiquitylation, self-association and function through AMBRA1 and TRAF6

(2013) Francesca Nazio et al.   NATURE CELL BIOLOGY

ULK1 induces autophagy by phosphorylating Beclin-1 and activating VPS34 lipid kinase

(2013) Ryan C. Russell et al.   NATURE CELL BIOLOGY

Proteostasis of polyglutamine varies among neurons and predicts neurodegeneration

(2013) Andrey S Tsvetkov et al.   Nature Chemical Biology

Chemical modulation of chaperone-mediated autophagy by retinoic acid derivatives

(2013) Jaime Anguiano et al.   Nature Chemical Biology

De novo mutations in the autophagy gene WDR45 cause static encephalopathy of childhood with neurodegeneration in adulthood

(2013) Hirotomo Saitsu et al.   NATURE GENETICS

Rev-erb-α modulates skeletal muscle oxidative capacity by regulating mitochondrial biogenesis and autophagy

(2013) Estelle Woldt et al.   NATURE MEDICINE

Mst1 inhibits autophagy by promoting the interaction between Beclin1 and Bcl-2

(2013) Yasuhiro Maejima et al.   NATURE MEDICINE

Interplay of LRRK2 with chaperone-mediated autophagy

(2013) Samantha J Orenstein et al.   NATURE NEUROSCIENCE

State of play in amyotrophic lateral sclerosis genetics

(2013) Alan E Renton et al.   NATURE NEUROSCIENCE

Signals from the lysosome: a control centre for cellular clearance and energy metabolism

(2013) Carmine Settembre et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

AD-linked, toxic NH2 human tau affects the quality control of mitochondria in neurons

(2013) G. Amadoro et al.   NEUROBIOLOGY OF DISEASE

Overexpression of autophagic proteins in the skeletal muscle of sporadic inclusion body myositis

(2013) F. Girolamo et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

The eIF2α/ATF4 pathway is essential for stress-induced autophagy gene expression

(2013) Wafa B’chir et al.   NUCLEIC ACIDS RESEARCH

The eukaryotic linear motif resource ELM: 10 years and counting

(2013) Holger Dinkel et al.   NUCLEIC ACIDS RESEARCH

Polyphenols: Multipotent Therapeutic Agents in Neurodegenerative Diseases

(2013) Khushwant S. Bhullar et al.   Oxidative Medicine and Cellular Longevity

Schwann cell autophagy counteracts the onset and chronification of neuropathic pain

(2013) Sara Marinelli et al.   PAIN

Emerging role of autophagy in pediatric neurodegenerative and neurometabolic diseases

(2013) Darius Ebrahimi-Fakhari et al.   PEDIATRIC RESEARCH

Autophagy in placentas from acidotic newborns: An immunohistochemical study of LC3 expression

(2013) L. Avagliano et al.   PLACENTA

The Deubiquitinating Enzyme AMSH1 and the ESCRT-III Subunit VPS2.1 Are Required for Autophagic Degradation in Arabidopsis

(2013) A. Katsiarimpa et al.   PLANT CELL

Disrupting Autophagy Restores Peroxisome Function to an Arabidopsis lon2 Mutant and Reveals a Role for the LON2 Protease in Peroxisomal Matrix Protein Degradation

(2013) L. M. Farmer et al.   PLANT CELL

Highly Oxidized Peroxisomes Are Selectively Degraded via Autophagy in Arabidopsis

(2013) M. Shibata et al.   PLANT CELL

Characterization of Growth Suppressive Functions of a Splice Variant of Cyclin D2

(2013) Karim Wafa et al.   PLoS One

P2X7 Integrates PI3K/AKT and AMPK-PRAS40-mTOR Signaling Pathways to Mediate Tumor Cell Death

(2013) Shu Bian et al.   PLoS One

mTOR-Controlled Autophagy Requires Intracellular Ca2+ Signaling

(2013) Jean-Paul Decuypere et al.   PLoS One

Deletion of Lipoprotein PG0717 in Porphyromonas gingivalis W83 Reduces Gingipain Activity and Alters Trafficking in and Response by Host Cells

(2013) Leticia Reyes et al.   PLoS One

Autophagy in the Human Placenta throughout Gestation

(2013) Tai-Ho Hung et al.   PLoS One

Increased autophagy in the placental territory of selective intrauterine growth-restricted monochorionic twins

(2013) Yao-Lung Chang et al.   PRENATAL DIAGNOSIS

Unique insights into maternal mitochondrial inheritance in mice

(2013) S.-M. Luo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Atg29 phosphorylation regulates coordination of the Atg17-Atg31-Atg29 complex with the Atg11 scaffold during autophagy initiation

(2013) K. Mao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Autosis is a Na+,K+-ATPase-regulated form of cell death triggered by autophagy-inducing peptides, starvation, and hypoxia-ischemia

(2013) Y. Liu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Decorin causes autophagy in endothelial cells via Peg3

(2013) S. Buraschi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The PINK1-Parkin pathway promotes both mitophagy and selective respiratory chain turnover in vivo

(2013) E. S. Vincow et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Reactive nitrogen species regulate autophagy through ATM-AMPK-TSC2-mediated suppression of mTORC1

(2013) D. N. Tripathi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Intrinsically disordered regions in autophagy proteins

(2013) Yang Mei et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Trehalose induced antidepressant-like effects and autophagy enhancement in mice

(2013) N. Z. Kara et al.   PSYCHOPHARMACOLOGY

Activation of Autophagy Rescues Amiodarone-Induced Apoptosis of Lung Epithelial Cells and Pulmonary Toxicity in Rats

(2013) Kang-Yo Lee et al.   TOXICOLOGICAL SCIENCES

Impairment of Atg5-Dependent Autophagic Flux Promotes Paraquat- and MPP+-Induced Apoptosis But Not Rotenone or 6-Hydroxydopamine Toxicity

(2013) Aracely Garcia-Garcia et al.   TOXICOLOGICAL SCIENCES

The Adaptive Endoplasmic Reticulum Stress Response to Lipotoxicity in Progressive Human Nonalcoholic Fatty Liver Disease

(2013) April D. Lake et al.   TOXICOLOGICAL SCIENCES

Hidden Behind Autophagy: The Unconventional Roles of ATG Proteins

(2013) Jovanka Bestebroer et al.   TRAFFIC

Autophagy and bacterial infection: an evolving arms race

(2013) Augustine Choy et al.   TRENDS IN MICROBIOLOGY

Autophagy: shaping the tumor microenvironment and therapeutic response

(2013) Hannelore Maes et al.   TRENDS IN MOLECULAR MEDICINE

Imaging endosomes and autophagosomes in whole mammalian cells using correlative cryo-fluorescence and cryo-soft X-ray microscopy (cryo-CLXM)

(2013) Elizabeth M.H. Duke et al.   ULTRAMICROSCOPY

BECN1 and BIM interactions with MCL-1 determine fludarabine resistance in leukemic B cells

(2013) A Sharma et al.   Cell Death & Disease

Iron modulates cell survival in a Ras- and MAPK-dependent manner in ovarian cells

(2013) K A Bauckman et al.   Cell Death & Disease

Saikosaponin-d, a novel SERCA inhibitor, induces autophagic cell death in apoptosis-defective cells

(2013) V KW Wong et al.   Cell Death & Disease

Calreticulin surface exposure is abrogated in cells lacking, chaperone-mediated autophagy-essential gene, LAMP2A

(2013) A D Garg et al.   Cell Death & Disease

Base excision repair AP endonucleases and mismatch repair act together to induce checkpoint-mediated autophagy

(2013) Tanima SenGupta et al.   Nature Communications

Spatiotemporally controlled induction of autophagy-mediated lysosome turnover

(2013) Yu-Hsien Hung et al.   Nature Communications

ATG5 is induced by DNA-damaging agents and promotes mitotic catastrophe independent of autophagy

(2013) Dipak Maskey et al.   Nature Communications

Involvement of mitochondrial dynamics in the segregation of mitochondrial matrix proteins during stationary phase mitophagy

(2013) Hagai Abeliovich et al.   Nature Communications

The VMP1-Beclin 1 interaction regulates autophagy induction

(2013) Maria I. Molejon et al.   Scientific Reports

A Targeted Genetic Modifier Screen Links the SWI2/SNF2 Protein Domino to Growth and Autophagy Genes in Drosophila melanogaster

(2013) Matt Hyoung Kwon et al.   G3-Genes Genomes Genetics

Global Analysis of Fission Yeast Mating Genes Reveals New Autophagy Factors

(2013) Ling-Ling Sun et al.   PLoS Genetics

The Zebrafish as a New Model for the In Vivo Study of Shigella flexneri Interaction with Phagocytes and Bacterial Autophagy

(2013) Serge Mostowy et al.   PLoS Pathogens

Autophagy and Human Parturition: Evaluation of LC3 Expression in Placenta from Spontaneous or Medically Induced Onset of Labor

(2013) Laura Avagliano et al.   Biomed Research International

Effect of tolerating macronutrient deficit on the development of intensive-care unit acquired weakness: a subanalysis of the EPaNIC trial

(2013) Greet Hermans et al.   Lancet Respiratory Medicine

Autophagy-dependent suppression of cancer immunogenicity and effector mechanisms of innate and adaptive immunity

(2013) Abhishek D Garg et al.   OncoImmunology

Comparative utility of LC3, p62 and TDP-43 immunohistochemistry in differentiation of inclusion body myositis from polymyositis and related inflammatory myopathies

(2013) Annie Hiniker et al.   Acta Neuropathologica Communications

Neuronal Autophagy and Neurodevelopmental Disorders

(2013) Kyung-Min Lee et al.   Experimental Neurobiology

Betulinic acid inhibits autophagic flux and induces apoptosis in human multiple myeloma cells in vitro

(2012) Li-jing Yang et al.   ACTA PHARMACOLOGICA SINICA

Avoiding transport bottlenecks in an expanding root system: Xylem vessel development in fibrous and pioneer roots under field conditions

(2012) Agnieszka Bagniewska-Zadworna et al.   AMERICAN JOURNAL OF BOTANY

Mutation in TECPR2 Reveals a Role for Autophagy in Hereditary Spastic Paraparesis

(2012) Danit Oz-Levi et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Exome Sequencing Reveals De Novo WDR45 Mutations Causing a Phenotypically Distinct, X-Linked Dominant Form of NBIA

(2012) Tobias B. Haack et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Autophagy Guards Against Cisplatin-Induced Acute Kidney Injury

(2012) Atsushi Takahashi et al.   AMERICAN JOURNAL OF PATHOLOGY

Comparison of Stain-Free gels with traditional immunoblot loading control methodology

(2012) Alex D. Colella et al.   ANALYTICAL BIOCHEMISTRY

Autophagy contributes to inflammation in patients with TNFR-associated periodic syndrome (TRAPS)

(2012) Tiziana Bachetti et al.   ANNALS OF THE RHEUMATIC DISEASES

Autophagy regulates TNFα-mediated joint destruction in experimental arthritis

(2012) Neng-Yu Lin et al.   ANNALS OF THE RHEUMATIC DISEASES

Immunogenic Cell Death in Cancer Therapy

(2012) Guido Kroemer et al.   Annual Review of Immunology

Lysosomal Iron, Iron Chelation, and Cell Death

(2012) Alexei Terman et al.   ANTIOXIDANTS & REDOX SIGNALING

Loss of the starvation-induced gene Rack1 leads to glycogen deficiency and impaired autophagic responses in Drosophila

(2012) Balázs Érdi et al.   Autophagy

A tethering coherent protein in autophagosome maturation

(2012) Dandan Chen et al.   Autophagy

Sorting nexin Snx41 is essential for conidiation and mediates glutathione-based antioxidant defense during invasive growth inMagnaporthe oryzae

(2012) Yi Zhen Deng et al.   Autophagy

Autophagy acts as a safeguard mechanism against G-quadruplex ligand-mediated DNA damage

(2012) Nicola Ivan Orlotti et al.   Autophagy

The plasma membrane as a control center for autophagy

(2012) Kevin Moreau et al.   Autophagy

ROS-induced mitochondrial depolarization initiates PARK2/PARKIN-dependent mitochondrial degradation by autophagy

(2012) Yuqing Wang et al.   Autophagy

Interpretation of bafilomycin, pH neutralizing or protease inhibitor treatments in autophagic flux experiments

(2012) Gábor Juhász   Autophagy

Induction of autophagy contributes to the neuroprotection of nicotinamide phosphoribosyltransferase in cerebral ischemia

(2012) Pei Wang et al.   Autophagy

Protective autophagy induced byRBX1/ROC1knockdown or CRL inactivation via modulating the DEPTOR-MTOR axis

(2012) Dongqin Yang et al.   Autophagy

The deubiquitinating enzyme USP36 controls selective autophagy activation by ubiquitinated proteins

(2012) Emmanuel Taillebourg et al.   Autophagy

KCS1deletion inSaccharomyces cerevisiaeleads to a defect in translocation of autophagic proteins and reduces autophagosome formation

(2012) Robert Taylor et al.   Autophagy

Blocking the interleukin 2 (IL2)-induced systemic autophagic syndrome promotes profound antitumor effects and limits toxicity

(2012) Michael T. Lotze et al.   Autophagy

Receptor protein complexes are in control of autophagy

(2012) Dalibor Mijaljica et al.   Autophagy

Isorhynchophylline, a natural alkaloid, promotes the degradation of alpha-synuclein in neuronal cells via inducing autophagy

(2012) Jia-Hong Lu et al.   Autophagy

ER stress inhibits neuronal death by promoting autophagy

(2012) Antoine Fouillet et al.   Autophagy

Lys05

(2012) Ravi K. Amaravadi et al.   Autophagy

A novel method for autophagy detection in primary cells

(2012) Kanchan Phadwal et al.   Autophagy

Exercise induces autophagy in peripheral tissues and in the brain

(2012) Congcong He et al.   Autophagy

MTORC1 functions as a transcriptional regulator of autophagy by preventing nuclear transport of TFEB

(2012) Jose A. Martina et al.   Autophagy

Monitoring autophagic flux by an improved tandem fluorescent-tagged LC3 (mTagRFP-mWasabi-LC3) reveals that high-dose rapamycin impairs autophagic flux in cancer cells

(2012) Cuihong Zhou et al.   Autophagy

TheC. elegansATG101 homolog EPG-9 directly interacts with EPG-1/Atg13 and is essential for autophagy

(2012) Qianqian Liang et al.   Autophagy

MAPK15/ERK8 stimulates autophagy by interacting with LC3 and GABARAP proteins

(2012) David Colecchia et al.   Autophagy

Carotenoid deficiency triggers autophagy in the model green algaChlamydomonas reinhardtii

(2012) María Esther Pérez-Pérez et al.   Autophagy

ATG16L1 and pathogenesis of urinary tract infections

(2012) Caihong Wang et al.   Autophagy

MicroRNAs in autophagy and their emerging roles in crosstalk with apoptosis

(2012) Jianzhen Xu et al.   Autophagy

Autophagy in lysosomal storage disorders

(2012) Andrew P. Lieberman et al.   Autophagy

Macroautophagy is deregulated in murine and human lupus T lymphocytes

(2012) Frédéric Gros et al.   Autophagy

In the beginning there was babble…

(2012) Daniel J Klionsky et al.   Autophagy

Guidelines for the use and interpretation of assays for monitoring autophagy

(2012) Daniel J. Klionsky et al.   Autophagy

Ceramide stress in survival versus lethal autophagy paradox

(2012) Wenhui Jiang et al.   Autophagy

Autophagy genesSmatg8andSmatg4are required for fruiting-body development, vegetative growth and ascospore germination in the filamentous ascomyceteSordaria macrospora

(2012) Oliver Voigt et al.   Autophagy

A novel role for the mitochondrial HTRA2/OMI protease in aging

(2012) Seokwon Kang et al.   Autophagy

A novel ER-localized transmembrane protein, EMC6, interacts with RAB5A and regulates cell autophagy

(2012) Yanjun Li et al.   Autophagy

Computational model for autophagic vesicle dynamics in single cells

(2012) Katie R. Martin et al.   Autophagy

“SR stress” in mixed hindlimb muscles of aging male rats

(2012) David W. Russ et al.   BIOGERONTOLOGY

Experimental evidence validating the computational inference of functional associations from gene fusion events: a critical survey

(2012) V. J. Promponas et al.   BRIEFINGS IN BIOINFORMATICS

VHL-Regulated MiR-204 Suppresses Tumor Growth through Inhibition of LC3B-Mediated Autophagy in Renal Clear Cell Carcinoma

(2012) Olga Mikhaylova et al.   CANCER CELL

The Nedd8-Activating Enzyme Inhibitor MLN4924 Induces Autophagy and Apoptosis to Suppress Liver Cancer Cell Growth

(2012) Z. Luo et al.   CANCER RESEARCH

Matrine, a novel autophagy inhibitor, blocks trafficking and the proteolytic activation of lysosomal proteases

(2012) Z. Wang et al.   CARCINOGENESIS

MicroRNA regulation of autophagy

(2012) L. B. Frankel et al.   CARCINOGENESIS

The Hairpin-type Tail-Anchored SNARE Syntaxin 17 Targets to Autophagosomes for Fusion with Endosomes/Lysosomes

(2012) Eisuke Itakura et al.   CELL

Architecture of the Atg17 Complex as a Scaffold for Autophagosome Biogenesis

(2012) Michael J. Ragusa et al.   CELL

Autophagy and apoptosis interplay during follicular atresia in fish ovary: a morphological and immunocytochemical study

(2012) R. D. V. S. Morais et al.   CELL AND TISSUE RESEARCH

Loss of a membrane trafficking protein αSNAP induces non-canonical autophagy in human epithelia

(2012) Nayden G. Naydenov et al.   CELL CYCLE

Pro-autophagic polyphenols reduce the acetylation of cytoplasmic proteins

(2012) Federico Pietrocola et al.   CELL CYCLE

Impairment of lysosomal integrity by B10, a glycosylated derivative of betulinic acid, leads to lysosomal cell death and converts autophagy into a detrimental process

(2012) P Gonzalez et al.   CELL DEATH AND DIFFERENTIATION

miRDeathDB: a database bridging microRNAs and the programmed cell death

(2012) J Xu et al.   CELL DEATH AND DIFFERENTIATION

Type 2 transglutaminase is involved in the autophagy-dependent clearance of ubiquitinated proteins

(2012) M D'Eletto et al.   CELL DEATH AND DIFFERENTIATION

TP53INP1, a tumor suppressor, interacts with LC3 and ATG8-family proteins through the LC3-interacting region (LIR) and promotes autophagy-dependent cell death

(2012) M Seillier et al.   CELL DEATH AND DIFFERENTIATION

Sestrin2 integrates Akt and mTOR signaling to protect cells against energetic stress-induced death

(2012) I Ben-Sahra et al.   CELL DEATH AND DIFFERENTIATION

Loss of HtrA2/Omi activity in non-neuronal tissues of adult mice causes premature aging

(2012) S Kang et al.   CELL DEATH AND DIFFERENTIATION

Phosphorylation of Atg5 by the Gadd45β–MEKK4-p38 pathway inhibits autophagy

(2012) E Keil et al.   CELL DEATH AND DIFFERENTIATION

Nondegradative Role of Atg5-Atg12/ Atg16L1 Autophagy Protein Complex in Antiviral Activity of Interferon Gamma

(2012) Seungmin Hwang et al.   Cell Host & Microbe

Pancreatic Acinar Cell-Specific Autophagy Disruption Reduces Coxsackievirus Replication and Pathogenesis In Vivo

(2012) Mehrdad Alirezaei et al.   Cell Host & Microbe

A Neuron-Specific Role for Autophagy in Antiviral Defense against Herpes Simplex Virus

(2012) Brian Yordy et al.   Cell Host & Microbe

Selective Subversion of Autophagy Complexes Facilitates Completion of the Brucella Intracellular Cycle

(2012) Tregei Starr et al.   Cell Host & Microbe

Wip1-Dependent Regulation of Autophagy, Obesity, and Atherosclerosis

(2012) Xavier Le Guezennec et al.   Cell Metabolism

Maintenance of Metabolic Homeostasis by Sestrin2 and Sestrin3

(2012) Jun Hee Lee et al.   Cell Metabolism

Sestrins Activate Nrf2 by Promoting p62-Dependent Autophagic Degradation of Keap1 and Prevent Oxidative Liver Damage

(2012) Soo Han Bae et al.   Cell Metabolism

A role of autophagy in Trypanosoma brucei cell death

(2012) Feng-Jun Li et al.   CELLULAR MICROBIOLOGY

Counteracting Autophagy Overcomes Resistance to Everolimus in Mantle Cell Lymphoma

(2012) L. Rosich et al.   CLINICAL CANCER RESEARCH

Insufficient Autophagy Contributes to Mitochondrial Dysfunction, Organ Failure, and Adverse Outcome in an Animal Model of Critical Illness*

(2012) Jan Gunst et al.   CRITICAL CARE MEDICINE

Phosphatidylinositol-3-Phosphate Clearance Plays a Key Role in Autophagosome Completion

(2012) Eduardo Cebollero et al.   CURRENT BIOLOGY

Cholesterol metabolism and cancer: the good, the bad and the ugly

(2012) Sandrine Silvente-Poirot et al.   CURRENT OPINION IN PHARMACOLOGY

Developmentally Programmed Nuclear Destruction during Yeast Gametogenesis

(2012) Michael D. Eastwood et al.   DEVELOPMENTAL CELL

Enlightening the impact of immunogenic cell death in photodynamic cancer therapy

(2012) Lorenzo Galluzzi et al.   EMBO JOURNAL

Genome-wide siRNA screen reveals amino acid starvation-induced autophagy requires SCOC and WAC

(2012) Nicole C McKnight et al.   EMBO JOURNAL

Pex3-anchored Atg36 tags peroxisomes for degradation inSaccharomyces cerevisiae

(2012) Alison M Motley et al.   EMBO JOURNAL

A novel pathway combining calreticulin exposure and ATP secretion in immunogenic cancer cell death

(2012) Abhishek D Garg et al.   EMBO JOURNAL

A lysosome-to-nucleus signalling mechanism senses and regulates the lysosome via mTOR and TFEB

(2012) Carmine Settembre et al.   EMBO JOURNAL

Mitochondrial processing peptidase regulates PINK1 processing, import and Parkin recruitment

(2012) Andrew W Greene et al.   EMBO REPORTS

Oncophagy: harnessing regulation of autophagy in cancer therapy

(2012) Justin S Gundara et al.   ENDOCRINE-RELATED CANCER

Early Parenteral Nutrition Evokes a Phenotype of Autophagy Deficiency in Liver and Skeletal Muscle of Critically Ill Rabbits

(2012) Sarah Derde et al.   ENDOCRINOLOGY

Role of ATG8 and Autophagy in Programmed Nuclear Degradation in Tetrahymena thermophila

(2012) Ming-Liang Liu et al.   EUKARYOTIC CELL

Autophagy induction extends lifespan and reduces lipid content in response to frataxin silencing in C. elegans

(2012) Alfonso Schiavi et al.   EXPERIMENTAL GERONTOLOGY

Targeting disease through novel pathways of apoptosis and autophagy

(2012) Kenneth Maiese et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Structural basis for protein phosphatase 1 regulation and specificity

(2012) Wolfgang Peti et al.   FEBS Journal

Lipofuscin is formed independently of macroautophagy and lysosomal activity in stress-induced prematurely senescent human fibroblasts

(2012) Annika Höhn et al.   FREE RADICAL BIOLOGY AND MEDICINE

Nitric oxide augments oridonin-induced efferocytosis by human histocytic lymphoma U937 cells via autophagy and the NF-κB-COX-2-IL-1β pathway

(2012) Linghe Zang et al.   FREE RADICAL RESEARCH

Abnormal Activation of Autophagy-Induced Crinophagy in Paneth Cells From Patients With Crohn's Disease

(2012) Élodie Thachil et al.   GASTROENTEROLOGY

Autophagy Releases Lipid That Promotes Fibrogenesis by Activated Hepatic Stellate Cells in Mice and in Human Tissues

(2012) Virginia Hernández–Gea et al.   GASTROENTEROLOGY

Molecular cloning, characterization and expression analysis of ATG1 in the silkworm, Bombyx mori

(2012) Barbara Casati et al.   GENE

Interactions between autophagic and endo-lysosomal markers in endothelial cells

(2012) Clara L. Oeste et al.   HISTOCHEMISTRY AND CELL BIOLOGY

TBK-1 Promotes Autophagy-Mediated Antimicrobial Defense by Controlling Autophagosome Maturation

(2012) Manohar Pilli et al.   IMMUNITY

Selective Autophagy of the Adaptor Protein Bcl10 Modulates T Cell Receptor Activation of NF-κB

(2012) Suman Paul et al.   IMMUNITY

Noncanonical Autophagy Is Required for Type I Interferon Secretion in Response to DNA-Immune Complexes

(2012) Jill Henault et al.   IMMUNITY

Expression of autophagy 8 (Atg8) and its role in the midgut and other organs of the greater wax moth, Galleria mellonella, during metamorphic remodelling and under starvation

(2012) D. B. Khoa et al.   INSECT MOLECULAR BIOLOGY

Aggregate Clearance of α-Synuclein inSaccharomyces cerevisiaeDepends More on Autophagosome and Vacuole Function Than on the Proteasome

(2012) Doris Petroi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Differential Function of the Two Atg4 Homologues in the Aggrephagy Pathway inCaenorhabditis elegans

(2012) Fan Wu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Regulation of Autophagy and Its Associated Cell Death by “Sphingolipid Rheostat”

(2012) Makoto Taniguchi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Novel AKT1-GLI3-VMP1 Pathway Mediates KRAS Oncogene-induced Autophagy in Cancer Cells

(2012) Andrea E. Lo Ré et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Autophagy-related Gene 14 (Atg14) Is Regulated by Forkhead Box O Transcription Factors and Circadian Rhythms and Plays a Critical Role in Hepatic Autophagy and Lipid Metabolism

(2012) Xiwen Xiong et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Protein Factor-arrest 11 (Far11) Is Essential for the Toxicity of Human Caspase-10 in Yeast and Participates in the Regulation of Autophagy and the DNA Damage Signaling

(2012) Patricia Lisa-Santamaría et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Microtubule-associated Protein 1 Light Chain 3 (LC3) Interacts with Bnip3 Protein to Selectively Remove Endoplasmic Reticulum and Mitochondria via Autophagy

(2012) Rita A. Hanna et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structure of the Novel C-terminal Domain of Vacuolar Protein Sorting 30/Autophagy-related Protein 6 and Its Specific Role in Autophagy

(2012) Nobuo N. Noda et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Parkin and Mitofusins Reciprocally Regulate Mitophagy and Mitochondrial Spheroid Formation

(2012) Wen-Xing Ding et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Electron Microscopic Analysis of a Spherical Mitochondrial Structure

(2012) Wen-Xing Ding et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structure-based Analyses Reveal Distinct Binding Sites for Atg2 and Phosphoinositides in Atg18

(2012) Yasunori Watanabe et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Autophagy genes function sequentially to promote apoptotic cell corpse degradation in the engulfing cell

(2012) Wei Li et al.   JOURNAL OF CELL BIOLOGY

TBC1D14 regulates autophagosome formation via Rab11- and ULK1-positive recycling endosomes

(2012) Andrea Longatti et al.   JOURNAL OF CELL BIOLOGY

Autophagy plays an essential role in the clearance of Pseudomonas aeruginosa by alveolar macrophages

(2012) K. Yuan et al.   JOURNAL OF CELL SCIENCE

NBR1 acts as an autophagy receptor for peroxisomes

(2012) E. Deosaran et al.   JOURNAL OF CELL SCIENCE

Investigation of the interactions of lupane type pentacyclic triterpenes with outer leaflet membrane phospholipids – Langmuir monolayer and synchrotron X-ray scattering study

(2012) Marcin Broniatowski et al.   JOURNAL OF COLLOID AND INTERFACE SCIENCE

Cell death and renewal during prey capture and digestion in the carnivorous sponge Asbestopluma hypogea (Porifera: Poecilosclerida)

(2012) C. Martinand-Mari et al.   JOURNAL OF EXPERIMENTAL BIOLOGY

Autophagy Regulates IL-23 Secretion and Innate T Cell Responses through Effects on IL-1 Secretion

(2012) C. Peral de Castro et al.   JOURNAL OF IMMUNOLOGY

Unregulated brain iron deposition in transgenic mice over-expressingHMOX1in the astrocytic compartment

(2012) Wei Song et al.   JOURNAL OF NEUROCHEMISTRY

The C-terminal domain of tetanus toxin protects motoneurons against acute excitotoxic damage on spinal cord organotypic cultures

(2012) Mireia Herrando-Grabulosa et al.   JOURNAL OF NEUROCHEMISTRY

Impaired Autophagy in Neurons after Disinhibition of Mammalian Target of Rapamycin and Its Contribution to Epileptogenesis

(2012) J. McMahon et al.   JOURNAL OF NEUROSCIENCE

Structural characterization and inhibition of the Plasmodium Atg8–Atg3 interaction

(2012) Adelaide U.P. Hain et al.   JOURNAL OF STRUCTURAL BIOLOGY

Activated protein C modulates cardiac metabolism and augments autophagy in the ischemic heart

(2012) R. COSTA et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Rab GTPase-Activating Proteins in Autophagy: Regulation of Endocytic and Autophagy Pathways by Direct Binding to Human ATG8 Modifiers

(2012) D. Popovic et al.   MOLECULAR AND CELLULAR BIOLOGY

BNip3 Regulates Mitochondrial Function and Lipid Metabolism in the Liver

(2012) D. Glick et al.   MOLECULAR AND CELLULAR BIOLOGY

Atg16L1, an essential factor for canonical autophagy, participates in hormone secretion from PC12 cells independently of autophagic activity

(2012) Koutaro Ishibashi et al.   MOLECULAR BIOLOGY OF THE CELL

Mammalian Atg2 proteins are essential for autophagosome formation and important for regulation of size and distribution of lipid droplets

(2012) Anoop Kumar G. Velikkakath et al.   MOLECULAR BIOLOGY OF THE CELL

Decoupling nutrient signaling from growth rate causes aerobic glycolysis and deregulation of cell size and gene expression

(2012) Nikolai Slavov et al.   MOLECULAR BIOLOGY OF THE CELL

Cell Differentiation within a Yeast Colony: Metabolic and Regulatory Parallels with a Tumor-Affected Organism

(2012) Michal Čáp et al.   MOLECULAR CELL

LC3C, Bound Selectively by a Noncanonical LIR Motif in NDP52, Is Required for Antibacterial Autophagy

(2012) Natalia von Muhlinen et al.   MOLECULAR CELL

Cytoplasmic STAT3 Represses Autophagy by Inhibiting PKR Activity

(2012) Shensi Shen et al.   MOLECULAR CELL

Two-Site Recognition of Phosphatidylinositol 3-Phosphate by PROPPINs in Autophagy

(2012) Sulochanadevi Baskaran et al.   MOLECULAR CELL

TBC1D7 Is a Third Subunit of the TSC1-TSC2 Complex Upstream of mTORC1

(2012) Christian C. Dibble et al.   MOLECULAR CELL

Androgens Promote Prostate Cancer Cell Growth through Induction of Autophagy

(2012) Yan Shi et al.   MOLECULAR ENDOCRINOLOGY

Global analysis of genome, transcriptome and proteome reveals the response to aneuploidy in human cells

(2012) Silvia Stingele et al.   Molecular Systems Biology

Exercise-induced BCL2-regulated autophagy is required for muscle glucose homeostasis

(2012) Congcong He et al.   NATURE

Galectin 8 targets damaged vesicles for autophagy to defend cells against bacterial invasion

(2012) Teresa L. M. Thurston et al.   NATURE

Selective autophagy degrades DICER and AGO2 and regulates miRNA activity

(2012) Derrick Gibbings et al.   NATURE CELL BIOLOGY

Autophagy receptors link myosin VI to autophagosomes to mediate Tom1-dependent autophagosome maturation and fusion with the lysosome

(2012) David A. Tumbarello et al.   NATURE CELL BIOLOGY

Mitochondrial outer-membrane protein FUNDC1 mediates hypoxia-induced mitophagy in mammalian cells

(2012) Lei Liu et al.   NATURE CELL BIOLOGY

Ceramide targets autophagosomes to mitochondria and induces lethal mitophagy

(2012) R David Sentelle et al.   Nature Chemical Biology

Recessive mutations in EPG5 cause Vici syndrome, a multisystem disorder with defective autophagy

(2012) Thomas Cullup et al.   NATURE GENETICS

A New Type of Compartment, Defined by Plant-Specific Atg8-Interacting Proteins, Is Induced upon Exposure of Arabidopsis Plants to Carbon Starvation

(2012) A. Honig et al.   PLANT CELL

Infection-Associated Nuclear Degeneration in the Rice Blast Fungus Magnaporthe oryzae Requires Non-Selective Macro-Autophagy

(2012) Min He et al.   PLoS One

DOR/Tp53inp2 and Tp53inp1 Constitute a Metazoan Gene Family Encoding Dual Regulators of Autophagy and Transcription

(2012) Ana Sancho et al.   PLoS One

Autophagy Mediates the Delivery of Thrombogenic Tissue Factor to Neutrophil Extracellular Traps in Human Sepsis

(2012) Konstantinos Kambas et al.   PLoS One

Carbon Monoxide Improves Cardiac Function and Mitochondrial Population Quality in a Mouse Model of Metabolic Syndrome

(2012) Steve Lancel et al.   PLoS One

Increased Autophagy in Placentas of Intrauterine Growth-Restricted Pregnancies

(2012) Tai-Ho Hung et al.   PLoS One

Autophagy-Related Atg8 Localizes to the Apicoplast of the Human Malaria Parasite Plasmodium falciparum

(2012) Kei Kitamura et al.   PLoS One

Advantages and Limitations of Different p62-Based Assays for Estimating Autophagic Activity in Drosophila

(2012) Karolina Pircs et al.   PLoS One

The E3-Ubiquitin Ligase TRIM50 Interacts with HDAC6 and p62, and Promotes the Sequestration and Clearance of Ubiquitinated Proteins into the Aggresome

(2012) Carmela Fusco et al.   PLoS One

Tetracycline Inhibits Local Inflammation Induced by Cerebral Ischemia via Modulating Autophagy

(2012) Yongjun Jiang et al.   PLoS One

TBK1 Kinase Addiction in Lung Cancer Cells Is Mediated via Autophagy of Tax1bp1/Ndp52 and Non-Canonical NF-κB Signalling

(2012) Alice C. Newman et al.   PLoS One

Endosomal Maturation, Rab7 GTPase and Phosphoinositides in African Swine Fever Virus Entry

(2012) Miguel A. Cuesta-Geijo et al.   PLoS One

Regulation of selective autophagy onset by a Ypt/Rab GTPase module

(2012) Z. Lipatova et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Myotubularin-related protein (MTMR) 9 determines the enzymatic activity, substrate specificity, and role in autophagy of MTMR8

(2012) J. Zou et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural and functional characterization of the two phosphoinositide binding sites of PROPPINs, a β-propeller protein family

(2012) Roswitha Krick et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

O-GlcNAc cycling mutants modulate proteotoxicity in Caenorhabditis elegans models of human neurodegenerative diseases

(2012) P. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Autophagosomes induced by a bacterial Beclin 1 binding protein facilitate obligatory intracellular infection

(2012) H. Niu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ume6 transcription factor is part of a signaling cascade that regulates autophagy

(2012) C. R. Bartholomew et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Autophagy inhibitor Lys05 has single-agent antitumor activity and reproduces the phenotype of a genetic autophagy deficiency

(2012) Q. McAfee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Drosophila Golgi membrane protein Ema promotes autophagosomal growth and function

(2012) S. Kim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Loss of P-type ATPase ATP13A2/PARK9 function induces general lysosomal deficiency and leads to Parkinson disease neurodegeneration

(2012) B. Dehay et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Degradation of the antiviral component ARGONAUTE1 by the autophagy pathway

(2012) B. Derrien et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Function and Molecular Mechanism of Acetylation in Autophagy Regulation

(2012) C. Yi et al.   SCIENCE

GSK3-TIP60-ULK1 Signaling Pathway Links Growth Factor Deprivation to Autophagy

(2012) S.-Y. Lin et al.   SCIENCE

Akt-Mediated Regulation of Autophagy and Tumorigenesis Through Beclin 1 Phosphorylation

(2012) R. C. Wang et al.   SCIENCE

Trs130 Participates in Autophagy Through GTPases Ypt31/32 inSaccharomyces cerevisiae

(2012) Shenshen Zou et al.   TRAFFIC

Autophagy intersections with conventional and unconventional secretion in tissue development, remodeling and inflammation

(2012) Vojo Deretic et al.   TRENDS IN CELL BIOLOGY

Bacterial autophagy: restriction or promotion of bacterial replication?

(2012) Serge Mostowy et al.   TRENDS IN CELL BIOLOGY

African swine fever virus-cell interactions: From virus entry to cell survival

(2012) Covadonga Alonso et al.   VIRUS RESEARCH

Early otic development depends on autophagy for apoptotic cell clearance and neural differentiation

(2012) M R Aburto et al.   Cell Death & Disease

Targeting Cullin-RING ligases by MLN4924 induces autophagy via modulating the HIF1-REDD1-TSC1-mTORC1-DEPTOR axis

(2012) Y Zhao et al.   Cell Death & Disease

JNK2 is activated during ER stress and promotes cell survival

(2012) M Raciti et al.   Cell Death & Disease

Regulation of autophagy by nucleoporin Tpr

(2012) Tatsuyoshi Funasaka et al.   Scientific Reports

PINK1-mediated phosphorylation of the Parkin ubiquitin-like domain primes mitochondrial translocation of Parkin and regulates mitophagy

(2012) Kahori Shiba-Fukushima et al.   Scientific Reports

Mouse Skeletal Muscle Fiber-Type-Specific Macroautophagy and Muscle Wasting Are Regulated by a Fyn/STAT3/Vps34 Signaling Pathway

(2012) Eijiro Yamada et al.   Cell Reports

PINK1 is activated by mitochondrial membrane potential depolarization and stimulates Parkin E3 ligase activity by phosphorylating Serine 65

(2012) C. Kondapalli et al.   Open Biology

The Salmonella Deubiquitinase SseL Inhibits Selective Autophagy of Cytosolic Aggregates

(2012) Francisco S. Mesquita et al.   PLoS Pathogens

Dual role of autophagy in HIV-1 replication and pathogenesis

(2012) M Killian   AIDS Research and Therapy

Use of LysoTracker to Detect Programmed Cell Death in Embryos and Differentiating Embryonic Stem Cells

(2012) Jennifer L. Fogel et al.   Jove-Journal of Visualized Experiments

The emergence of phox-ER stress induced immunogenic apoptosis

(2012) Abhishek D. Garg et al.   OncoImmunology

Age-related changes in the function of autophagy in rat kidneys

(2011) Jing Cui et al.   AGE

Biogenesis and Cargo Selectivity of Autophagosomes

(2011) Hilla Weidberg et al.   Annual Review of Biochemistry

The Role of Atg Proteins in Autophagosome Formation

(2011) Noboru Mizushima et al.   Annual Review of Cell and Developmental Biology

Stationary-Phase Mitophagy in Respiring Saccharomyces cerevisiae

(2011) Hagai Abeliovich   ANTIOXIDANTS & REDOX SIGNALING

Absence of Tumor Suppressor Tumor Protein 53-Induced Nuclear Protein 1 (TP53INP1) Sensitizes Mouse Thymocytes and Embryonic Fibroblasts to Redox-Driven Apoptosis

(2011) Prudence N'guessan et al.   ANTIOXIDANTS & REDOX SIGNALING

Lysosomal Function and Dysfunction: Mechanism and Disease

(2011) Patricia Boya   ANTIOXIDANTS & REDOX SIGNALING

Autophagy precedes apoptosis during the remodeling of silkworm larval midgut

(2011) Eleonora Franzetti et al.   APOPTOSIS

Common Proteomic Changes in the Hippocampus in Schizophrenia and Bipolar Disorder and Particular Evidence for Involvement of Cornu Ammonis Regions 2 and 3

(2011) Melanie Föcking et al.   ARCHIVES OF GENERAL PSYCHIATRY

Spatiotemporally controlled initiation of Parkin-mediated mitophagy within single cells

(2011) Jin-Yi Yang et al.   Autophagy

I think autophagy controls the death of my cells: What do I do to get my paper published?

(2011) Andrew Thorburn   Autophagy

Analyzing autophagy inMagnaporthe oryzae

(2011) Fei Xu et al.   Autophagy

Evolution of the “autophagamiR”

(2011) Justin S. Gundara et al.   Autophagy

PARP and RIP 1 are required for autophagy induced by 11'-deoxyverticillin A, which precedes caspase-dependent apoptosis

(2011) Nan Zhang et al.   Autophagy

A fluorescence-microscopic and cytofluorometric system for monitoring the turnover of the autophagic substrate p62/SQSTM1

(2011) Amena BenYounès et al.   Autophagy

GFP-Atg8 protease protection as a tool to monitor autophagosome biogenesis

(2011) Usha Nair et al.   Autophagy

Induction of autophagy by drug-resistant esophageal cancer cells promotes their survival and recovery following treatment with chemotherapeutics

(2011) Tracey R. O’Donovan et al.   Autophagy

ATRA-induced upregulation of Beclin 1 prolongs the life span of differentiated acute promyelocytic leukemia cells

(2011) Aurore Trocoli et al.   Autophagy

A comprehensive siRNA screen for kinases that suppress macroautophagy in optimal growth conditions

(2011) Piotr Szyniarowski et al.   Autophagy

The autophagosome is overrated!

(2011) Daniel J Klionsky   Autophagy

Vps34 is a phosphatidylinositol 3-kinase, not a phosphoinositide 3-kinase

(2011) Alfred J. Meijer et al.   Autophagy

Do plastids inDendrobiumcv. Lucky Duan petals function similar to autophagosomes and autolysosomes?

(2011) Wouter G. van Doorn et al.   Autophagy

Autophagic activity measured in whole rat hepatocytes as the accumulation of a novel BHMT fragment (p10), generated in amphisomes by the asparaginyl proteinase, legumain

(2011) Anders Øverbye et al.   Autophagy

Stimulation of ALK by the growth factor midkine renders glioma cells resistant to autophagy-mediated cell death

(2011) Mar Lorente et al.   Autophagy

Characterization of macroautophagic flux in vivo using a leupeptin-based assay

(2011) Jeffrey Haspel et al.   Autophagy

Simultaneous assessment of autophagy and apoptosis using multispectral imaging cytometry

(2011) Claire de la Calle et al.   Autophagy

AMPK and mTOR coordinate the regulation of Ulk1 and mammalian autophagy initiation

(2011) Libin Shang et al.   Autophagy

Double membranes vs. lipid bilayers, and their significance for correct identification of macroautophagic structures

(2011) Eeva-Liisa Eskelinen et al.   Autophagy

A comprehensive glossary of autophagy-related molecules and processes (2ndedition)

(2011) Daniel J Klionsky et al.   Autophagy

Identification and functional analysis of Joka2, a tobacco member of the family of selective autophagy cargo receptors

(2011) Katarzyna Zientara-Rytter et al.   Autophagy

Plant NBR1 is a selective autophagy substrate and a functional hybrid of the mammalian autophagic adapters NBR1 and p62/SQSTM1

(2011) Steingrim Svenning et al.   Autophagy

CUP-5, theC. elegansortholog of the mammalian lysosomal channel protein MLN1/TRPML1, is required for proteolytic degradation in autolysosomes

(2011) Tao Sun et al.   Autophagy

The coiled-coil domain protein EPG-8 plays an essential role in the autophagy pathway inC. elegans

(2011) Peiguo Yang et al.   Autophagy

The acquisition of resistance to TNFα in breast cancer cells is associated with constitutive activation of autophagy as revealed by a transcriptome analysis using a custom microarray

(2011) Etienne Moussay et al.   Autophagy

GABARAPL1 (GEC1): Original or copycat?

(2011) Jaclyn Nicole Le Grand et al.   Autophagy

p62, Ref(2)P and ubiquitinated proteins are conserved markers of neuronal aging, aggregate formation and progressive autophagic defects

(2011) Bryan J. Bartlett et al.   Autophagy

Ins(1,4,5)P3receptor-mediated Ca2+signaling and autophagy induction are interrelated

(2011) Jean-Paul Decuypere et al.   Autophagy

The Atg6/Vps30/Beclin 1 ortholog BEC-1 mediates endocytic retrograde transport in addition to autophagy inC. elegans

(2011) Alexander Ruck et al.   Autophagy

A proteolytic cleavage assay to monitor autophagy inDictyostelium discoideum

(2011) Javier Calvo-Garrido et al.   Autophagy

Atg35, a micropexophagy-specific protein that regulates micropexophagic apparatus formation inPichia pastoris

(2011) Volodymyr Y. Nazarko et al.   Autophagy

Autophagy-independent function of MAP-LC3 during intracellular propagation ofChlamydia trachomatis

(2011) Hesham M. Al-Younes et al.   Autophagy

ULK1 inhibits the kinase activity of mTORC1 and cell proliferation

(2011) Chang Hwa Jung et al.   Autophagy

Atg1 allows second-signaled autophagic cell death in Dictyostelium

(2011) Marie-Françoise Luciani et al.   Autophagy

Autophagy in protists

(2011) Michael Duszenko et al.   Autophagy

Sea urchin embryos as a model system for studying autophagy induced by cadmium stress

(2011) Roberto Chiarelli et al.   Autophagy

The induction of autophagy by mechanical stress

(2011) Jason S. King et al.   Autophagy

Resveratrol-mediated autophagy requires WIPI-1-regulated LC3 lipidation in the absence of induced phagophore formation

(2011) Mario Mauthe et al.   Autophagy

Mitochondria removal by autophagy

(2011) Ke Wang et al.   Autophagy

For the last time, it is GFP-Atg8, not Atg8-GFP (and the same goes for LC3)

(2011) Daniel J Klionsky   Autophagy

Caffeine induces apoptosis by enhancement of autophagy via PI3K/Akt/mTOR/p70S6K inhibition

(2011) Shinji Saiki et al.   Autophagy

Coronavirus nsp6 proteins generate autophagosomes from the endoplasmic reticulum via an omegasome intermediate

(2011) Eleanor M. Cottam et al.   Autophagy

The autophagy initiating kinase ULK1 is regulated via opposing phosphorylation by AMPK and mTOR

(2011) Dan Egan et al.   Autophagy

Seeing is believing: The impact of electron microscopy on autophagy research

(2011) Eeva-Liisa Eskelinen et al.   Autophagy

ULK1 inhibits mTORC1 signaling, promotes multisite Raptor phosphorylation and hinders substrate binding

(2011) Elaine A. Dunlop et al.   Autophagy

Ulk1-mediated phosphorylation of AMPK constitutes a negative regulatory feedback loop

(2011) Antje S. Löffler et al.   Autophagy

Dissecting the dynamic turnover of GFP-LC3 in the autolysosome

(2011) Hong-Min Ni et al.   Autophagy

Atg13 and FIP200 act independently of Ulk1 and Ulk2 in autophagy induction

(2011) Sebastian Alers et al.   Autophagy

Hepatitis B virus X protein reduces starvation-induced cell death through activation of autophagy and inhibition of mitochondrial apoptotic pathway

(2011) Yi Mao et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Improved structure, function and compatibility for CellProfiler: modular high-throughput image analysis software

(2011) Lee Kamentsky et al.   BIOINFORMATICS

Autophagy induced by rapamycin and carbon-starvation have distinct proteome profiles in Aspergillus nidulans

(2011) Yonghyun Kim et al.   BIOTECHNOLOGY AND BIOENGINEERING

BCR-ABL suppresses autophagy through ATF5-mediated regulation of mTOR transcription

(2011) Z. Sheng et al.   BLOOD

MiR-17/20/93/106 promote hematopoietic cell expansion by targeting sequestosome 1-regulated pathways in mice

(2011) A. Meenhuis et al.   BLOOD

Concurrent detection of autolysosome formation and lysosomal degradation by flow cytometry in a high-content screen for inducers of autophagy

(2011) Phillip Hundeshagen et al.   BMC BIOLOGY

Expression of autophagy-related genes in the anterior silk gland of the silkworm (Bombyx mori) during metamorphosis

(2011) Qingrong Li et al.   CANADIAN JOURNAL OF ZOOLOGY

Spectral imaging-based methods for quantifying autophagy and apoptosis

(2011) Nathan G. Dolloff et al.   CANCER BIOLOGY & THERAPY

Atorvastatin induces autophagy in prostate cancer PC3 cells through activation ofLC3transcription

(2011) Nicholas Toepfer et al.   CANCER BIOLOGY & THERAPY

Histone deacetylase inhibition induces apoptosis and autophagy in human neuroblastoma cells

(2011) Roser Francisco et al.   CANCER LETTERS

Following Cytochrome c Release, Autophagy Is Inhibited during Chemotherapy-Induced Apoptosis by Caspase 8-Mediated Cleavage of Beclin 1

(2011) H. Li et al.   CANCER RESEARCH

SNARE Proteins Are Required for Macroautophagy

(2011) Usha Nair et al.   CELL

RalB and the Exocyst Mediate the Cellular Starvation Response by Direct Activation of Autophagosome Assembly

(2011) Brian O. Bodemann et al.   CELL

Class IIa Histone Deacetylases Are Hormone-Activated Regulators of FOXO and Mammalian Glucose Homeostasis

(2011) Maria M. Mihaylova et al.   CELL

Identification of Aneuploidy-Selective Antiproliferation Compounds

(2011) Yun-Chi Tang et al.   CELL

Autophagosome Precursor Maturation Requires Homotypic Fusion

(2011) Kevin Moreau et al.   CELL

Beclin1 Controls the Levels of p53 by Regulating the Deubiquitination Activity of USP10 and USP13

(2011) Junli Liu et al.   CELL

A dual role for Ca2+ in autophagy regulation

(2011) Jean-Paul Decuypere et al.   CELL CALCIUM

Stimulation of the midkine/ALK axis renders glioma cells resistant to cannabinoid antitumoral action

(2011) M Lorente et al.   CELL DEATH AND DIFFERENTIATION

Autophagy promotes survival of retinal ganglion cells after optic nerve axotomy in mice

(2011) N Rodríguez-Muela et al.   CELL DEATH AND DIFFERENTIATION

PKD is a kinase of Vps34 that mediates ROS-induced autophagy downstream of DAPk

(2011) A Eisenberg-Lerner et al.   CELL DEATH AND DIFFERENTIATION

Autophagy and BiP level decrease are early key events in retrograde degeneration of motoneurons

(2011) C Penas et al.   CELL DEATH AND DIFFERENTIATION

Mitochondrially localized PKA reverses mitochondrial pathology and dysfunction in a cellular model of Parkinson's disease

(2011) R K Dagda et al.   CELL DEATH AND DIFFERENTIATION

The Beclin 1 network regulates autophagy and apoptosis

(2011) R Kang et al.   CELL DEATH AND DIFFERENTIATION

Morphological classification of plant cell deaths

(2011) W G van Doorn et al.   CELL DEATH AND DIFFERENTIATION

A Tecpr1-Dependent Selective Autophagy Pathway Targets Bacterial Pathogens

(2011) Michinaga Ogawa et al.   Cell Host & Microbe

Autophagy Regulates Cholesterol Efflux from Macrophage Foam Cells via Lysosomal Acid Lipase

(2011) Mireille Ouimet et al.   Cell Metabolism

Eating the strangers within: host control of intracellular bacteria via xenophagy

(2011) Leigh A. Knodler et al.   CELLULAR MICROBIOLOGY

A Sensitive and Quantitative Technique for Detecting Autophagic Events Based on Lysosomal Delivery

(2011) Hiroyuki Katayama et al.   CHEMISTRY & BIOLOGY

Importance of cholesterol and oxysterols metabolism in the pharmacology of tamoxifen and other AEBS ligands

(2011) Philippe de Medina et al.   CHEMISTRY AND PHYSICS OF LIPIDS

Autophagy and p62 in Cardiac Proteinopathy

(2011) Qingwen Zheng et al.   CIRCULATION RESEARCH

Novel Phosphoinositide 3-Kinase/mTOR Dual Inhibitor, NVP-BGT226, Displays Potent Growth-Inhibitory Activity against Human Head and Neck Cancer Cells In Vitro and In Vivo

(2011) K.-Y. Chang et al.   CLINICAL CANCER RESEARCH

The p62 antibody reveals various cytoplasmic protein aggregates in spinocerebellar ataxia Type 6

(2011) K. Seidel et al.   CLINICAL NEUROPATHOLOGY

Autophagy and Lipid Metabolism Coordinately Modulate Life Span in Germline-less C. elegans

(2011) Louis R. Lapierre et al.   CURRENT BIOLOGY

The Professional Phagocyte Dictyostelium discoideum as a Model Host for Bacterial Pathogens

(2011) Salvatore Bozzaro et al.   CURRENT DRUG TARGETS

Origin and function of the stalk-cell vacuole in Dictyostelium

(2011) Toru Uchikawa et al.   DEVELOPMENTAL BIOLOGY

Autophagy Proteins Regulate the Secretory Component of Osteoclastic Bone Resorption

(2011) Carl J. DeSelm et al.   DEVELOPMENTAL CELL

The WD40 Repeat PtdIns(3)P-Binding Protein EPG-6 Regulates Progression of Omegasomes to Autophagosomes

(2011) Qun Lu et al.   DEVELOPMENTAL CELL

Microautophagy of Cytosolic Proteins by Late Endosomes

(2011) Ranjit Sahu et al.   DEVELOPMENTAL CELL

Inhibition of autophagy by TAB2 and TAB3

(2011) Alfredo Criollo et al.   EMBO JOURNAL

Autophagy-based unconventional secretory pathway for extracellular delivery of IL-1β

(2011) Nicolas Dupont et al.   EMBO JOURNAL

Temporal orchestration of circadian autophagy rhythm by C/EBPβ

(2011) Di Ma et al.   EMBO JOURNAL

p53 directly suppresses BNIP3 expression to protect against hypoxia-induced cell death

(2011) Xi Feng et al.   EMBO JOURNAL

microRNA-101 is a potent inhibitor of autophagy

(2011) Lisa B Frankel et al.   EMBO JOURNAL

BAG3 mediates chaperone-based aggresome-targeting and selective autophagy of misfolded proteins

(2011) Martin Gamerdinger et al.   EMBO REPORTS

Role and regulation of autophagy in the development of acinar structures formed by bovine BME-UV1 mammary epithelial cells

(2011) Agnieszka Sobolewska et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

At the core of survival: Autophagy delays the onset of both apoptotic and necrotic cell death in a model of ischemic cell injury

(2011) B. Loos et al.   EXPERIMENTAL CELL RESEARCH

Transmembrane protein 166 regulates autophagic and apoptotic activities following focal cerebral ischemic injury in rats

(2011) Li Li et al.   EXPERIMENTAL NEUROLOGY

Functional interaction of heat shock protein 90 and Beclin 1 modulates Toll-like receptor-mediated autophagy

(2011) Congfeng Xu et al.   FASEB JOURNAL

Defective relocalization of ALS2/alsin missense mutants to Rac1-induced macropinosomes accounts for loss of their cellular function and leads to disturbed amphisome formation

(2011) Asako Otomo et al.   FEBS LETTERS

Cytotoxicity of red fluorescent protein DsRed is associated with the suppression of Bcl-xL translation

(2011) Jun Zhou et al.   FEBS LETTERS

Lysosomal thiol reductase negatively regulates autophagy by altering glutathione synthesis and oxidation

(2011) Hao-Sen Chiang et al.   FREE RADICAL BIOLOGY AND MEDICINE

Molecular cross-talk between the NRF2/KEAP1 signaling pathway, autophagy, and apoptosis

(2011) Tomasz M. Stępkowski et al.   FREE RADICAL BIOLOGY AND MEDICINE

AMP-activated protein kinase--an energy sensor that regulates all aspects of cell function

(2011) D. G. Hardie   GENES & DEVELOPMENT

High Beclin 1 expression defines a poor prognosis in endometrial adenocarcinomas

(2011) Alexandra Giatromanolaki et al.   GYNECOLOGIC ONCOLOGY

Muscle choline kinase beta defect causes mitochondrial dysfunction and increased mitophagy

(2011) Satomi Mitsuhashi et al.   HUMAN MOLECULAR GENETICS

Lafora bodies and neurological defects in malin-deficient mice correlate with impaired autophagy

(2011) Olga Criado et al.   HUMAN MOLECULAR GENETICS

Silencing of frataxin gene expression triggers p53-dependent apoptosis in human neuron-like cells

(2011) G. M. Palomo et al.   HUMAN MOLECULAR GENETICS

Characterization of the CLEAR network reveals an integrated control of cellular clearance pathways

(2011) Michela Palmieri et al.   HUMAN MOLECULAR GENETICS

Functional alteration of PARL contributes to mitochondrial dysregulation in Parkinson's disease

(2011) Guang Shi et al.   HUMAN MOLECULAR GENETICS

Broad activation of the ubiquitin–proteasome system by Parkin is critical for mitophagy

(2011) Nickie C. Chan et al.   HUMAN MOLECULAR GENETICS

Autophagy in immunity and cell-autonomous defense against intracellular microbes

(2011) Vojo Deretic   IMMUNOLOGICAL REVIEWS

Autophagy modulates the Mycobacterium tuberculosis-induced cytokine response

(2011) Johanneke Kleinnijenhuis et al.   IMMUNOLOGY

The role of lysosomes in iron metabolism and recycling

(2011) Tino Kurz et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Peroxisome degradation in mammals

(2011) Junji Ezaki et al.   IUBMB LIFE

Crucial role for autophagy in degranulation of mast cells

(2011) Hiroko Ushio et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

TGF -activated kinase 1 (TAK1)-binding proteins (TAB) 2 and 3 negatively regulate autophagy

(2011) G. Takaesu et al.   JOURNAL OF BIOCHEMISTRY

Regulation of Autophagy by Neuropathological Protein TDP-43

(2011) Jayarama Krishnan Bose et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Fatty Acids Suppress Autophagic Turnover in β-Cells

(2011) Guy Las et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Hierarchical Whole-body Modeling Approach Elucidates the Link betweenin VitroInsulin Signaling andin VivoGlucose Homeostasis

(2011) Elin Nyman et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Flavivirus NS4A-induced Autophagy Protects Cells against Death and Enhances Virus Replication

(2011) Jeffrey E. McLean et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Identification of Small Molecule Inhibitors of Phosphatidylinositol 3-Kinase and Autophagy

(2011) Thomas Farkas et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Aspartyl Aminopeptidase Is Imported from the Cytoplasm to the Vacuole by Selective Autophagy inSaccharomyces cerevisiae

(2011) Masaki Yuga et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Novel TIP30 Protein Complex Regulates EGF Receptor Signaling and Endocytic Degradation

(2011) Chengliang Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Nicotinic Acid Adenine Dinucleotide Phosphate (NAADP) Regulates Autophagy in Cultured Astrocytes

(2011) Gustavo J. S. Pereira et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Parkin Mediates Proteasome-dependent Protein Degradation and Rupture of the Outer Mitochondrial Membrane

(2011) Saori R. Yoshii et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Dynamics of the Degradation of Ubiquitinated Proteins by Proteasomes and Autophagy

(2011) Natura Myeku et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Activation of Autophagy of Aggregation-prone Ubiquitinated Proteins by Timosaponin A-III

(2011) Chun-Nam Lok et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Glucocorticoid Elevation of Dexamethasone-induced Gene 2 (Dig2/RTP801/REDD1) Protein Mediates Autophagy in Lymphocytes

(2011) Jason K. Molitoris et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Autophagy Controls IL-1β Secretion by Targeting Pro-IL-1β for Degradation

(2011) James Harris et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Microtubule-associated Protein 1S (MAP1S) Bridges Autophagic Components with Microtubules and Mitochondria to Affect Autophagosomal Biogenesis and Degradation

(2011) Rui Xie et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

OATL1, a novel autophagosome-resident Rab33B-GAP, regulates autophagosomal maturation

(2011) Takashi Itoh et al.   JOURNAL OF CELL BIOLOGY

Two MAPK-signaling pathways are required for mitophagy inSaccharomyces cerevisiae

(2011) Kai Mao et al.   JOURNAL OF CELL BIOLOGY

Biogenesis of a novel compartment for autophagosome-mediated unconventional protein secretion

(2011) Caroline Bruns et al.   JOURNAL OF CELL BIOLOGY

Autophagic substrate clearance requires activity of the syntaxin-5 SNARE complex

(2011) M. Renna et al.   JOURNAL OF CELL SCIENCE

Identification of PTP  as an autophagic phosphatase

(2011) K. R. Martin et al.   JOURNAL OF CELL SCIENCE

Chaperone-mediated autophagy at a glance

(2011) S. Kaushik et al.   JOURNAL OF CELL SCIENCE

Freeze-fracture replica immunolabelling reveals human WIPI-1 and WIPI-2 as membrane proteins of autophagosomes

(2011) Tassula Proikas-Cezanne et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

The novel phloroglucinol PMT7 kills glycolytic cancer cells by blocking autophagy and sensitizing to nutrient stress

(2011) Kate Broadley et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Insufficient Activation of Autophagy Allows Cellular Damage to Accumulate in Critically Ill Patients

(2011) Ilse Vanhorebeek et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Parkin is a lipid-responsive regulator of fat uptake in mice and mutant human cells

(2011) Kye-Young Kim et al.   JOURNAL OF CLINICAL INVESTIGATION

Autophagic Activity and Aging in Human Odontoblasts

(2011) E. Couve et al.   JOURNAL OF DENTAL RESEARCH

Retrograde heart perfusion: The Langendorff technique of isolated heart perfusion

(2011) Robert M. Bell et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Induction of autophagy with catalytic mTOR inhibitors reduces huntingtin aggregates in a neuronal cell model

(2011) Ana Roscic et al.   JOURNAL OF NEUROCHEMISTRY

The mitochondrial intramembrane protease PARL cleaves human Pink1 to regulate Pink1 trafficking

(2011) Cathrin Meissner et al.   JOURNAL OF NEUROCHEMISTRY

Presenilin Is Necessary for Efficient Proteolysis through the Autophagy-Lysosome System in a  -Secretase-Independent Manner

(2011) K. M. Neely et al.   JOURNAL OF NEUROSCIENCE

Lysosomal Proteolysis Inhibition Selectively Disrupts Axonal Transport of Degradative Organelles and Causes an Alzheimer's-Like Axonal Dystrophy

(2011) S. Lee et al.   JOURNAL OF NEUROSCIENCE

Autophagy Protects the Proximal Tubule from Degeneration and Acute Ischemic Injury

(2011) T. Kimura et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Zoledronic Acid Induces Autophagic Cell Death in Human Prostate Cancer Cells

(2011) Ji-Fan Lin et al.   JOURNAL OF UROLOGY

Autophagosome Formation during Varicella-Zoster Virus Infection following Endoplasmic Reticulum Stress and the Unfolded Protein Response

(2011) J. E. Carpenter et al.   JOURNAL OF VIROLOGY

Pleiotropic Action of AP-1 in v-Src-Transformed Cells

(2011) L. Wang et al.   JOURNAL OF VIROLOGY

Inhibition of active autophagy induces apoptosis and increases chemosensitivity in cholangiocarcinoma

(2011) Yu-Jie Hou et al.   LABORATORY INVESTIGATION

Beclin-1 and LC3A expression in cutaneous malignant melanomas

(2011) Efthimios Sivridis et al.   MELANOMA RESEARCH

Autophagy patterns and prognosis in uveal melanomas

(2011) Alexandra N Giatromanolaki et al.   MODERN PATHOLOGY

A Conserved Coatomer-related Complex Containing Sec13 and Seh1 Dynamically Associates With the Vacuole inSaccharomyces cerevisiae

(2011) Svetlana Dokudovskaya et al.   MOLECULAR & CELLULAR PROTEOMICS

Autophagy Driven by a Master Regulator of Hematopoiesis

(2011) Y.-A. Kang et al.   MOLECULAR AND CELLULAR BIOLOGY

Distinct Mechanisms of Ferritin Delivery to Lysosomes in Iron-Depleted and Iron-Replete Cells

(2011) T. Asano et al.   MOLECULAR AND CELLULAR BIOLOGY

Relieving Autophagy and 4EBP1 from Rapamycin Resistance

(2011) B. Nyfeler et al.   MOLECULAR AND CELLULAR BIOLOGY

A GDI (AGS3) and a GEF (GIV) regulate autophagy by balancing G protein activity and growth factor signals

(2011) Mikel Garcia-Marcos et al.   MOLECULAR BIOLOGY OF THE CELL

The LC3 recruitment mechanism is separate from Atg9L1-dependent membrane formation in the autophagic response against Salmonella

(2011) Shun Kageyama et al.   MOLECULAR BIOLOGY OF THE CELL

Selective regulation of autophagy by the Iml1-Npr2-Npr3 complex in the absence of nitrogen starvation

(2011) Xi Wu et al.   MOLECULAR BIOLOGY OF THE CELL

A Lipid-Modified Estrogen Derivative that Treats Breast Cancer Independent of Estrogen Receptor Expression through Simultaneous Induction of Autophagy and Apoptosis

(2011) S. Sinha et al.   MOLECULAR CANCER RESEARCH

Blockade of Fatty Acid Synthase Induces Ubiquitination and Degradation of Phosphoinositide-3-Kinase Signaling Proteins in Ovarian Cancer

(2011) K. Tomek et al.   MOLECULAR CANCER RESEARCH

p62 Is a Key Regulator of Nutrient Sensing in the mTORC1 Pathway

(2011) Angeles Duran et al.   MOLECULAR CELL

Serine 403 Phosphorylation of p62/SQSTM1 Regulates Selective Autophagic Clearance of Ubiquitinated Proteins

(2011) Gen Matsumoto et al.   MOLECULAR CELL

Complex Inhibitory Effects of Nitric Oxide on Autophagy

(2011) Sovan Sarkar et al.   MOLECULAR CELL

Hsp90-Cdc37 Chaperone Complex Regulates Ulk1- and Atg13-Mediated Mitophagy

(2011) Joung Hyuck Joo et al.   MOLECULAR CELL

Distinct Autophagosomal-Lysosomal Fusion Mechanism Revealed by Thapsigargin-Induced Autophagy Arrest

(2011) Ian G. Ganley et al.   MOLECULAR CELL

Ca2+/Calmodulin-Dependent Kinase (CaMK) Signaling via CaMKI and AMP-Activated Protein Kinase Contributes to the Regulation of WIPI-1 at the Onset of Autophagy

(2011) S. G. Pfisterer et al.   MOLECULAR PHARMACOLOGY

Image-based genome-wide siRNA screen identifies selective autophagy factors

(2011) Anthony Orvedahl et al.   NATURE

HDACs link the DNA damage response, processing of double-strand breaks and autophagy

(2011) Thomas Robert et al.   NATURE

Autophagy in immunity and inflammation

(2011) Beth Levine et al.   NATURE

Cdk5-mediated phosphorylation of endophilin B1 is required for induced autophagy in models of Parkinson's disease

(2011) Alan S. L. Wong et al.   NATURE CELL BIOLOGY

During autophagy mitochondria elongate, are spared from degradation and sustain cell viability

(2011) Ligia C. Gomes et al.   NATURE CELL BIOLOGY

Autophagy machinery mediates macroendocytic processing and entotic cell death by targeting single membranes

(2011) Oliver Florey et al.   NATURE CELL BIOLOGY

AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1

(2011) Joungmok Kim et al.   NATURE CELL BIOLOGY

AMP-activated protein kinase: nature's energy sensor

(2011) David Carling et al.   Nature Chemical Biology

A synonymous variant in IRGM alters a binding site for miR-196 and causes deregulation of IRGM-dependent xenophagy in Crohn's disease

(2011) Patrick Brest et al.   NATURE GENETICS

Autophagy induced by valproic acid is associated with oxidative stress in glioma cell lines

(2011) J. Fu et al.   NEURO-ONCOLOGY

Lanatoside C sensitizes glioblastoma cells to tumor necrosis factor–related apoptosis-inducing ligand and induces an alternative cell death pathway

(2011) Christian E. Badr et al.   NEURO-ONCOLOGY

ATP13A2 regulates mitochondrial bioenergetics through macroautophagy

(2011) Aaron M. Gusdon et al.   NEUROBIOLOGY OF DISEASE

The accumulation of neurotoxic proteins, induced by proteasome inhibition, is reverted by trehalose, an enhancer of autophagy, in human neuroblastoma cells

(2011) M.J. Casarejos et al.   NEUROCHEMISTRY INTERNATIONAL

Restriction of trophic factors and nutrients induces PARKIN expression

(2011) M. Klinkenberg et al.   NEUROGENETICS

Macroautophagy and the proteasome are differently involved in the degradation of alpha-synuclein wild type and mutated A30P in an in vitro inducible model (PC12/TetOn)

(2011) S. Batelli et al.   NEUROSCIENCE

NAC1 modulates sensitivity of ovarian cancer cells to cisplatin by altering the HMGB1-mediated autophagic response

(2011) Y Zhang et al.   ONCOGENE

Cloning and characterization of the autophagy-related gene 6 from the hard tick, Haemaphysalis longicornis

(2011) Suguru Kawano et al.   PARASITOLOGY RESEARCH

Autophagy in term normal human placentas

(2011) P. Signorelli et al.   PLACENTA

TheArabidopsisDeubiquitinating Enzyme AMSH3 Interacts with ESCRT-III Subunits and Regulates Their Localization

(2011) Anthi Katsiarimpa et al.   PLANT CELL

TheArabidopsisMultistress Regulator TSPO Is a Heme Binding Membrane Protein and a Potential Scavenger of Porphyrins via an Autophagy-Dependent Degradation Mechanism

(2011) Celine Vanhee et al.   PLANT CELL

The ATG1/ATG13 Protein Kinase Complex Is Both a Regulator and a Target of Autophagic Recycling in Arabidopsis

(2011) A. Suttangkakul et al.   PLANT CELL

Delivery of Prolamins to the Protein Storage Vacuole in Maize Aleurone Cells

(2011) Francisca C. Reyes et al.   PLANT CELL

BAG3 Directly Interacts with Mutated alphaB-Crystallin to Suppress Its Aggregation and Toxicity

(2011) Akinori Hishiya et al.   PLoS One

Downregulation of VRK1 by p53 in Response to DNA Damage Is Mediated by the Autophagic Pathway

(2011) Alberto Valbuena et al.   PLoS One

Unc-51/ATG1 Controls Axonal and Dendritic Development via Kinesin-Mediated Vesicle Transport in the Drosophila Brain

(2011) Hiroaki Mochizuki et al.   PLoS One

The Metabolic Consequences of Hepatic AMP-Kinase Phosphorylation in Rainbow Trout

(2011) Sergio Polakof et al.   PLoS One

Preconditioning Involves Selective Mitophagy Mediated by Parkin and p62/SQSTM1

(2011) Chengqun Huang et al.   PLoS One

SB202190-Induced Cell Type-Specific Vacuole Formation and Defective Autophagy Do Not Depend on p38 MAP Kinase Inhibition

(2011) Manoj B. Menon et al.   PLoS One

Activation of Autophagy in a Rat Model of Retinal Ischemia following High Intraocular Pressure

(2011) Antonio Piras et al.   PLoS One

rnaset2 mutant zebrafish model familial cystic leukoencephalopathy and reveal a role for RNase T2 in degrading ribosomal RNA

(2011) N. Haud et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Glycogen synthase kinase (GSK)-3 promotes p70 ribosomal protein S6 kinase (p70S6K) activity and cell proliferation

(2011) S. Shin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Nrf2-mediated induction of p62 controls Toll-like receptor-4-driven aggresome-like induced structure formation and autophagic degradation

(2011) K.-i. Fujita et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Autophagosome targeting and membrane curvature sensing by Barkor/Atg14(L)

(2011) W. Fan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

RNS2, a conserved member of the RNase T2 family, is necessary for ribosomal RNA decay in plants

(2011) M. S. Hillwig et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Microtubule-associated protein 1 light chain 3 alpha (LC3)-associated phagocytosis is required for the efficient clearance of dead cells

(2011) J. Martinez et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Nutrient starvation elicits an acute autophagic response mediated by Ulk1 dephosphorylation and its subsequent dissociation from AMPK

(2011) L. Shang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Spinster is required for autophagic lysosome reformation and mTOR reactivation following starvation

(2011) Y. Rong et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ammonia-induced autophagy is independent of ULK1/ULK2 kinases

(2011) H. Cheong et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Emerging role of p62/sequestosome-1 in the pathogenesis of Alzheimer's disease

(2011) Antero Salminen et al.   PROGRESS IN NEUROBIOLOGY

Autophagy contributes to resistance of tumor cells to ionizing radiation

(2011) Hassan Chaachouay et al.   RADIOTHERAPY AND ONCOLOGY

mTORC1 Senses Lysosomal Amino Acids Through an Inside-Out Mechanism That Requires the Vacuolar H+-ATPase

(2011) R. Zoncu et al.   SCIENCE

Phosphorylation of the Autophagy Receptor Optineurin Restricts Salmonella Growth

(2011) P. Wild et al.   SCIENCE

Degradation of Paternal Mitochondria by Fertilization-Triggered Autophagy in C. elegans Embryos

(2011) M. Sato et al.   SCIENCE

Autophagy-Dependent Anticancer Immune Responses Induced by Chemotherapeutic Agents in Mice

(2011) M. Michaud et al.   SCIENCE

Spatial Coupling of mTOR and Autophagy Augments Secretory Phenotypes

(2011) M. Narita et al.   SCIENCE

TFEB Links Autophagy to Lysosomal Biogenesis

(2011) C. Settembre et al.   SCIENCE

Conditional Peripheral Membrane Proteins: Facing up to Limited Specificity

(2011) Katarina Moravcevic et al.   STRUCTURE

Autophagy Regulates the Post-Translational Cleavage of BCL-2 and Promotes Neuronal Survival

(2011) Laura Lossi et al.   TheScientificWorldJOURNAL

The Development of an Immunohistochemical Method to Detect the Autophagy-Associated Protein LC3-II in Human Tumor Xenografts

(2011) Sarah V. Holt et al.   TOXICOLOGIC PATHOLOGY

Chelation of Lysosomal Iron Protects Dopaminergic SH-SY5Y Neuroblastoma Cells from Hydrogen Peroxide Toxicity by Precluding Autophagy and Akt Dephosphorylation

(2011) Roberta Castino et al.   TOXICOLOGICAL SCIENCES

Dengue Virus and Autophagy

(2011) Nicholas S. Heaton et al.   Viruses-Basel

A photoconvertible fluorescent reporter to track chaperone-mediated autophagy

(2011) Hiroshi Koga et al.   Nature Communications

Atg8: an autophagy-related ubiquitin-like protein family

(2011) Tomer Shpilka et al.   GENOME BIOLOGY

Autophagy in basal hyphal compartments: A green strategy of great recyclers

(2011) Jun-ya Shoji et al.   Fungal Biology Reviews

LC3A-Positive Light Microscopy Detected Patterns of Autophagy and Prognosis in Operable Breast Carcinomas

(2010) Efthimios Sivridis et al.   AMERICAN JOURNAL OF PATHOLOGY

Autophagy in health and disease. 3. Involvement of autophagy in muscle atrophy

(2010) Marco Sandri   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

The Receptor for Advanced Glycation End-Products (RAGE) Protects Pancreatic Tumor Cells Against Oxidative Injury

(2010) Rui Kang et al.   ANTIOXIDANTS & REDOX SIGNALING

The execution phase of autophagy associated PCD during insect metamorphosis

(2010) Caroline O. B. Facey et al.   APOPTOSIS

Accumulation of Non-Superoxide Anion Reactive Oxygen Species Mediates Nitrogen-Limited Alcoholic Fermentation by Saccharomyces cerevisiae

(2010) A. Mendes-Ferreira et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Purification of autophagosomes from rat hepatocytes

(2010) Per O. Seglen et al.   Autophagy

Autophagy in Dictyostelium: Genes and pathways, cell death and infection

(2010) Javier Calvo-Garrido et al.   Autophagy

Elevated Beclin 1 expression is correlated with HIF-1α in predicting poor prognosis of nasopharyngeal carcinoma

(2010) Xiang-Bo Wan et al.   Autophagy

Determining Atg protein stoichiometry at the phagophore assembly site by fluorescence microscopy

(2010) Jiefei Geng et al.   Autophagy

Autophagy, ferritin and iron chelation

(2010) Ivana De Domenico et al.   Autophagy

Larval midgut destruction in Drosophila: Not dependent on caspases but suppressed by the loss of autophagy

(2010) Donna Denton et al.   Autophagy

Autophagy in 2020 and beyond: eating our way into a healthy future

(2010) Dalibor Mijaljica   Autophagy

Reticulocyte mitophagy: Monitoring mitochondrial clearance in a mammalian model

(2010) Ji Zhang et al.   Autophagy

Increased expression of ATG genes during nonfeeding periods in the tickHaemaphysalis longicornis

(2010) Rika Umemiya-Shirafuji et al.   Autophagy

AMPK- and p62/SQSTM1-dependent autophagy mediate Resveratrol-induced cell death in chronic myelogenous leukemia

(2010) Alexandre Puissant et al.   Autophagy

Synthetic substrates for measuring activity of autophagy proteases-autophagins (Atg4)

(2010) Chih-Wen Shu et al.   Autophagy

Quantitative proteomics for the analysis of spatio-temporal protein dynamics during autophagy

(2010) Andrea C. Zimmermann et al.   Autophagy

GABARAPL1 (GEC1) associates with autophagic vesicles

(2010) Fatima Zahra Chakrama et al.   Autophagy

Characterization of autophagosome formation site by a hierarchical analysis of mammalian Atg proteins

(2010) Eisuke Itakura et al.   Autophagy

Activation of Atg1 kinase in autophagy by regulated phosphorylation

(2010) Monika Kijanska et al.   Autophagy

Autophagy and its physiological relevance in arthropods: Current knowledge and perspectives

(2010) Davide Malagoli et al.   Autophagy

A reporter cell system to monitor autophagy based on p62/SQSTM1

(2010) Kenneth Bowitz Larsen et al.   Autophagy

Activation of autophagy and Akt/CREB signaling play an equivalent role in the neuroprotective effect of rapamycin in neonatal hypoxia-ischemia

(2010) Silvia Carloni et al.   Autophagy

Electron tomography reveals the endoplasmic reticulum as a membrane source for autophagosome formation

(2010) Mitsuko Hayashi-Nishino et al.   Autophagy

The in vitro cleavage of the hAtg proteins by cell death proteases

(2010) Joanna M. Norman et al.   Autophagy

p62/SQSTM1 and ALFY interact to facilitate the formation of p62 bodies/ALIS and their degradation by autophagy

(2010) Terje Høyvarde Clausen et al.   Autophagy

Quantitation of "autophagic flux" in mature skeletal muscle

(2010) Jeong-Sun Ju et al.   Autophagy

The cysteine protease MoAtg4 interacts with MoAtg8 and is required for differentiation and pathogenesis inMagnaporthe oryzae

(2010) Tong-Bao Liu et al.   Autophagy

A vacuolar glucoamylase, Sga1, participates in glycogen autophagy for proper asexual differentiation inMagnaporthe oryzae

(2010) Yi Zhen Deng et al.   Autophagy

The autophagosomal protein LGG-2 acts synergistically with LGG-1 in dauer formation and longevity in C. elegans

(2010) Adriana Alberti et al.   Autophagy

Beclin 1 expression: A predictor of prognosis in patients with extranodal natural killer T-cell lymphoma, nasal type

(2010) Jia-Jia Huang et al.   Autophagy

Evidence for the interplay between JNK and p53-DRAM signaling pathways in the regulation of autophagy

(2010) Séverine Lorin et al.   Autophagy

Autophagy dysfunction and ubiquitin-positive protein aggregates in Dictyostelium cells lacking Vmp1

(2010) Javier Calvo-Garrido et al.   Autophagy

Methods to monitor autophagy inH. pylorivacuolating cytotoxin A (VacA)-treated cells

(2010) Deepa Raju et al.   Autophagy

Gigantic macroautophagy in programmed nuclear death ofTetrahymena thermophila

(2010) Takahiko Akematsu et al.   Autophagy

Investigating autophagy: Quantitative morphometric analysis using electron microscopy

(2010) Jamie M. Swanlund et al.   Autophagy

Targeting Beclin 1 for viral subversion of macroautophagy

(2010) Monique Gannagé et al.   Autophagy

A comprehensive glossary of autophagy-related molecules and processes

(2010) Daniel J. Klionsky et al.   Autophagy

Control of basal autophagy by calpain1 mediated cleavage of ATG5

(2010) Hong-Guang Xia et al.   Autophagy

Quantification of nonselective bulk autophagy inS. cerevisiaeusing Pgk1-GFP

(2010) Evelyn Welter et al.   Autophagy

VCP/p97 is essential for maturation of ubiquitin-containing autophagosomes and this function is impaired by mutations that cause IBMPFD

(2010) Emilie Tresse et al.   Autophagy

Processing of autophagic protein LC3 by the 20S proteasome

(2010) Zhonghua Gao et al.   Autophagy

A novel quantitative flow cytometry-based assay for autophagy

(2010) Kai Er Eng et al.   Autophagy

Mammalian Atg18 (WIPI2) localizes to omegasome-anchored phagophores and positively regulates LC3 lipidation

(2010) Hannah E.J. Polson et al.   Autophagy

The PINK1/Parkin-mediated mitophagy is compromised by PD-associated mutations

(2010) Sven Geisler et al.   Autophagy

Traf6 and A20 differentially regulate TLR4-Induced autophagy by affecting the ubiquitination of Beclin 1

(2010) Chong-Shan Shi et al.   Autophagy

Autophagy in endometrial carcinomas and prognostic relevance of 'stone-like' structures (SLS): What is destined for the atypical endometrial hyperplasia?

(2010) Efthimios Sivridis et al.   Autophagy

What is the advantage of a transient precursor in autophagosome biogenesis?

(2010) Nicholas T. Ktistakis et al.   Autophagy

Antibacterial autophagy occurs at PI(3)P-enriched domains of the endoplasmic reticulum and requires Rab1 GTPase

(2010) Ju Huang et al.   Autophagy

A quantitative assay for the monitoring of autophagosome accumulation in different phases of the cell cycle

(2010) Vitaliy Kaminskyy et al.   Autophagy

Compound C induces protective autophagy in cancer cells through AMPK inhibition-independent blockade of Akt/mTOR pathway

(2010) Ljubica Vucicevic et al.   Autophagy

Binding preference of p62 towards LC3-ll during dopaminergic neurotoxin-induced impairment of autophagic flux

(2010) Junghyun Lim et al.   Autophagy

Fasting-related autophagic response in slow- and fast-twitch skeletal muscle

(2010) Tomonori Ogata et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

PI3K/p110  is a novel therapeutic target in multiple myeloma

(2010) H. Ikeda et al.   BLOOD

Autophagy contributes to therapy-induced degradation of the PML/RARA oncoprotein

(2010) P. Isakson et al.   BLOOD

microRNA-dependent modulation of histone acetylation in Waldenstrom macroglobulinemia

(2010) A. M. Roccaro et al.   BLOOD

Roles of CUP-5, the Caenorhabditis elegans orthologue of human TRPML1, in lysosome and gut granule biogenesis

(2010) Erin M Campbell et al.   BMC CELL BIOLOGY

Acetylated microtubules are required for fusion of autophagosomes with lysosomes

(2010) Rui Xie et al.   BMC CELL BIOLOGY

Characterization of the rainbow trout transcriptome using Sanger and 454-pyrosequencing approaches

(2010) Mohamed Salem et al.   BMC GENOMICS

Adaptation of Hansenula polymorpha to methanol: a transcriptome analysis

(2010) Tim van Zutphen et al.   BMC GENOMICS

Reversal of autophagy dysfunction in the TgCRND8 mouse model of Alzheimer's disease ameliorates amyloid pathologies and memory deficits

(2010) Dun-Sheng Yang et al.   BRAIN

Beclin 1 over- and underexpression in colorectal cancer: distinct patterns relate to prognosis and tumour hypoxia

(2010) M I Koukourakis et al.   BRITISH JOURNAL OF CANCER

DJ-1, a cancer and Parkinson’s disease associated protein, regulates autophagy through JNK pathway in cancer cells

(2010) Haigang Ren et al.   CANCER LETTERS

The RB-E2F1 Pathway Regulates Autophagy

(2010) H. Jiang et al.   CANCER RESEARCH

Jun Proteins Are Starvation-Regulated Inhibitors of Autophagy

(2010) O. Yogev et al.   CANCER RESEARCH

ATG12 Conjugation to ATG3 Regulates Mitochondrial Homeostasis and Cell Death

(2010) Lilliana Radoshevich et al.   CELL

C. elegans Screen Identifies Autophagy Genes Specific to Multicellular Organisms

(2010) Ye Tian et al.   CELL

Lysosomal Proteolysis and Autophagy Require Presenilin 1 and Are Disrupted by Alzheimer-Related PS1 Mutations

(2010) Ju-Hyun Lee et al.   CELL

Essential Regulation of Cell Bioenergetics by Constitutive InsP3 Receptor Ca2+ Transfer to Mitochondria

(2010) César Cárdenas et al.   CELL

Omi/HtrA2 is a positive regulator of autophagy that facilitates the degradation of mutant proteins involved in neurodegenerative diseases

(2010) B Li et al.   CELL DEATH AND DIFFERENTIATION

Sphingosine-1-phosphate phosphohydrolase-1 regulates ER stress-induced autophagy

(2010) S Lépine et al.   CELL DEATH AND DIFFERENTIATION

Regulation of autophagic activity by 14-3-3ζ proteins associated with class III phosphatidylinositol-3-kinase

(2010) M Pozuelo-Rubio   CELL DEATH AND DIFFERENTIATION

The Parkinson-associated protein PINK1 interacts with Beclin1 and promotes autophagy

(2010) S Michiorri et al.   CELL DEATH AND DIFFERENTIATION

Autophagy in Drosophila ovaries is induced by starvation and is required for oogenesis

(2010) J M I Barth et al.   CELL DEATH AND DIFFERENTIATION

Coronaviruses Hijack the LC3-I-Positive EDEMosomes, ER-Derived Vesicles Exporting Short-Lived ERAD Regulators, for Replication

(2010) Fulvio Reggiori et al.   Cell Host & Microbe

A Diacylglycerol-Dependent Signaling Pathway Contributes to Regulation of Antibacterial Autophagy

(2010) Shahab Shahnazari et al.   Cell Host & Microbe

Entrapment of Intracytosolic Bacteria by Septin Cage-like Structures

(2010) Serge Mostowy et al.   Cell Host & Microbe

Use of Cells Expressing γ Subunit Variants to Identify Diverse Mechanisms of AMPK Activation

(2010) Simon A. Hawley et al.   Cell Metabolism

Defective Hepatic Autophagy in Obesity Promotes ER Stress and Causes Insulin Resistance

(2010) Ling Yang et al.   Cell Metabolism

Neutrophil extracellular trap cell death requires both autophagy and superoxide generation

(2010) Quinten Remijsen et al.   CELL RESEARCH

Loss of Dictyostelium ATG9 results in a pleiotropic phenotype affecting growth, development, phagocytosis and clearance and replication of Legionella pneumophila

(2010) Sze Man Tung et al.   CELLULAR MICROBIOLOGY

Autophagosomes can support Yersinia pseudotuberculosis replication in macrophages

(2010) Kevin Moreau et al.   CELLULAR MICROBIOLOGY

AMPK-independent induction of autophagy by cytosolic Ca2+ increase

(2010) Antje Grotemeier et al.   CELLULAR SIGNALLING

Light-Chain 3A Autophagic Activity and Prognostic Significance in Non-small Cell Lung Carcinomas

(2010) Georgia Karpathiou et al.   CHEST

Profound Cardioprotection With Chloramphenicol Succinate in the Swine Model of Myocardial Ischemia-Reperfusion Injury

(2010) J. A. Sala-Mercado et al.   CIRCULATION

Deacetylation of FoxO by Sirt1 Plays an Essential Role in Mediating Starvation-Induced Autophagy in Cardiac Myocytes

(2010) Nirmala Hariharan et al.   CIRCULATION RESEARCH

Immunogenic Tumor Cell Death for Optimal Anticancer Therapy: The Calreticulin Exposure Pathway

(2010) L. Zitvogel et al.   CLINICAL CANCER RESEARCH

An in vivo and in vitro assessment of autophagy-related gene expression in muscle of rainbow trout (Oncorhynchus mykiss)

(2010) Iban Seiliez et al.   COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY

Disentangling the Role of the Tau Gene Locus in Sporadic Tauopathies

(2010) J. Vandrovcova et al.   Current Alzheimer Research

Protein Secretion: Unconventional Exit by Exophagy

(2010) Hilde Abrahamsen et al.   CURRENT BIOLOGY

Chaperone-Assisted Selective Autophagy Is Essential for Muscle Maintenance

(2010) Verena Arndt et al.   CURRENT BIOLOGY

DAP1, a Novel Substrate of mTOR, Negatively Regulates Autophagy

(2010) Itay Koren et al.   CURRENT BIOLOGY

The role of the Atg1/ULK1 complex in autophagy regulation

(2010) Noboru Mizushima   CURRENT OPINION IN CELL BIOLOGY

Chaperone-mediated autophagy in protein quality control

(2010) Esperanza Arias et al.   CURRENT OPINION IN CELL BIOLOGY

Mechanisms and consequences of bacterial targeting by the autophagy pathway

(2010) Shahab Shahnazari et al.   CURRENT OPINION IN MICROBIOLOGY

A Genome-Wide siRNA Screen Reveals Multiple mTORC1 Independent Signaling Pathways Regulating Autophagy under Normal Nutritional Conditions

(2010) Marta M. Lipinski et al.   DEVELOPMENTAL CELL

MCL-1 is a stress sensor that regulates autophagy in a developmentally regulated manner

(2010) Marc Germain et al.   EMBO JOURNAL

LC3 and GATE-16/GABARAP subfamilies are both essential yet act differently in autophagosome biogenesis

(2010) Hilla Weidberg et al.   EMBO JOURNAL

Atg1-mediated myosin II activation regulates autophagosome formation during starvation-induced autophagy

(2010) Hong-Wen Tang et al.   EMBO JOURNAL

HDAC6 controls autophagosome maturation essential for ubiquitin-selective quality-control autophagy

(2010) Joo-Yong Lee et al.   EMBO JOURNAL

The BH3-only Bnip3 binds to the dynamin Opa1 to promote mitochondrial fragmentation and apoptosis by distinct mechanisms

(2010) Thomas Landes et al.   EMBO REPORTS

Cdc48 and Ufd3, new partners of the ubiquitin protease Ubp3, are required for ribophagy

(2010) Batool Ossareh-Nazari et al.   EMBO REPORTS

Red but not dead? Membranes of stressed Saccharomyces cerevisiae are permeable to propidium iodide

(2010) H. M. Davey et al.   ENVIRONMENTAL MICROBIOLOGY

Regulation of the autophagic machinery in human neutrophils

(2010) Ioannis Mitroulis et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Activity-dependent neuroprotective protein (ADNP) expression level is correlated with the expression of the sister protein ADNP2: Deregulation in schizophrenia

(2010) Efrat Dresner et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

The melanoma-associated transmembrane glycoprotein Gpnmb controls trafficking of cellular debris for degradation and is essential for tissue repair

(2010) Bing Li et al.   FASEB JOURNAL

Novel synthetic small-molecule activators of AMPK as enhancers of autophagy and amyloid-β peptide degradation

(2010) Valérie Vingtdeux et al.   FASEB JOURNAL

Molecular mechanism and physiological role of pexophagy

(2010) Ravi Manjithaya et al.   FEBS LETTERS

Role of autophagy in Caenorhabditis elegans

(2010) Attila Lajos Kovacs et al.   FEBS LETTERS

Atg8-family interacting motif crucial for selective autophagy

(2010) Nobuo N. Noda et al.   FEBS LETTERS

The Cvt pathway as a model for selective autophagy

(2010) Melinda A. Lynch-Day et al.   FEBS LETTERS

Involvement of apoptosis and autophagy in reducing mouse hepatoma ML-1 cell growth in inbred BALB/c mice by bacterial fermented soybean products

(2010) Chun-Li Su et al.   FOOD AND CHEMICAL TOXICOLOGY

Autophagy-related lipase FgATG15 of Fusarium graminearum is important for lipid turnover and plant infection

(2010) Long Nam Nguyen et al.   FUNGAL GENETICS AND BIOLOGY

Autophagy Reduces Acute Ethanol-Induced Hepatotoxicity and Steatosis in Mice

(2010) Wen–Xing Ding et al.   GASTROENTEROLOGY

Autophosphorylation Within the Atg1 Activation Loop Is Required for Both Kinase Activity and the Induction of Autophagy in Saccharomyces cerevisiae

(2010) Y.-Y. Yeh et al.   GENETICS

Evidence for the involvement of mTOR inhibition and basal autophagy in familial Mediterranean fever phenotype

(2010) Ioannis Mitroulis et al.   HUMAN IMMUNOLOGY

Zebrafish MTMR14 is required for excitation–contraction coupling, developmental motor function and the regulation of autophagy

(2010) J.J. Dowling et al.   HUMAN MOLECULAR GENETICS

A pivotal role for PINK1 and autophagy in mitochondrial quality control: implications for Parkinson disease

(2010) C. T. Chu   HUMAN MOLECULAR GENETICS

Laforin, the most common protein mutated in Lafora disease, regulates autophagy

(2010) Carmen Aguado et al.   HUMAN MOLECULAR GENETICS

In Vivo Requirement for Atg5 in Antigen Presentation by Dendritic Cells

(2010) Heung Kyu Lee et al.   IMMUNITY

Human Immunodeficiency Virus-1 Inhibition of Immunoamphisomes in Dendritic Cells Impairs Early Innate and Adaptive Immune Responses

(2010) Fabien P. Blanchet et al.   IMMUNITY

Delivery of Cytosolic Components by Autophagic Adaptor Protein p62 Endows Autophagosomes with Unique Antimicrobial Properties

(2010) Marisa Ponpuak et al.   IMMUNITY

TwoTorgenes in the silkwormBombyx mori

(2010) S. Zhou et al.   INSECT MOLECULAR BIOLOGY

AMP-activated Protein Kinase Signaling Activation by Resveratrol Modulates Amyloid-β Peptide Metabolism

(2010) Valérie Vingtdeux et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

LC3-dependent Intracellular Membrane Tubules Induced by γ-Protocadherins A3 and B2

(2010) Hugo H. Hanson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Selective Transport of α-Mannosidase by Autophagic Pathways

(2010) Yasunori Watanabe et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The PEA-15 Protein Regulates Autophagy via Activation of JNK

(2010) Barbara C. Böck et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Lucanthone Is a Novel Inhibitor of Autophagy That Induces Cathepsin D-mediated Apoptosis

(2010) Jennifer S. Carew et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Inhibition of Autophagosome Formation by the Benzoporphyrin Derivative Verteporfin

(2010) Elizabeth Donohue et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Dual Role of 3-Methyladenine in Modulation of Autophagy via Different Temporal Patterns of Inhibition on Class I and III Phosphoinositide 3-Kinase

(2010) You-Tong Wu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The TOR Complex 1 Is Distributed in Endosomes and in Retrograde Vesicles That Form from the Vacuole Membrane and Plays an Important Role in the Vacuole Import and Degradation Pathway

(2010) C. Randell Brown et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

p62/SQSTM1Is a Target Gene for Transcription Factor NRF2 and Creates a Positive Feedback Loop by Inducing Antioxidant Response Element-driven Gene Transcription

(2010) Ashish Jain et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Kinetics Comparisons of Mammalian Atg4 Homologues Indicate Selective Preferences toward Diverse Atg8 Substrates

(2010) Min Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Antioxidant Transcription Factor Nrf2 Negatively Regulates Autophagy and Growth Arrest Induced by the Anticancer Redox Agent Mitoquinone

(2010) V. Ashutosh Rao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Macroautophagy Is Not Directly Involved in the Metabolism of Amyloid Precursor Protein

(2010) Barry Boland et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Chemical Inducers of Autophagy That Enhance the Clearance of Mutant Proteins in Neurodegenerative Diseases

(2010) Maurizio Renna et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Zymophagy, a Novel Selective Autophagy Pathway Mediated by VMP1-USP9x-p62, Prevents Pancreatic Cell Death

(2010) Daniel Grasso et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Proteasome and p97 mediate mitophagy and degradation of mitofusins induced by Parkin

(2010) Atsushi Tanaka et al.   JOURNAL OF CELL BIOLOGY

Cdc48/p97 and Shp1/p47 regulate autophagosome biogenesis in concert with ubiquitin-like Atg8

(2010) Roswitha Krick et al.   JOURNAL OF CELL BIOLOGY

Disease-causing mutations in Parkin impair mitochondrial ubiquitination, aggregation, and HDAC6-dependent mitophagy

(2010) Joo-Yong Lee et al.   JOURNAL OF CELL BIOLOGY

Regulation of the autophagy protein LC3 by phosphorylation

(2010) Salvatore J. Cherra et al.   JOURNAL OF CELL BIOLOGY

A yeast MAPK cascade regulates pexophagy but not other autophagy pathways

(2010) Ravi Manjithaya et al.   JOURNAL OF CELL BIOLOGY

The class IA phosphatidylinositol 3-kinase p110-β subunit is a positive regulator of autophagy

(2010) Zhixun Dou et al.   JOURNAL OF CELL BIOLOGY

Unconventional secretion of Acb1 is mediated by autophagosomes

(2010) Juan M. Duran et al.   JOURNAL OF CELL BIOLOGY

Unconventional secretion ofPichia pastorisAcb1 is dependent on GRASP protein, peroxisomal functions, and autophagosome formation

(2010) Ravi Manjithaya et al.   JOURNAL OF CELL BIOLOGY

Mitochondrial membrane potential regulates PINK1 import and proteolytic destabilization by PARL

(2010) Seok Min Jin et al.   JOURNAL OF CELL BIOLOGY

Autophagic degradation of dBruce controls DNA fragmentation in nurse cells during lateDrosophila melanogasteroogenesis

(2010) Ioannis P. Nezis et al.   JOURNAL OF CELL BIOLOGY

The dynamic interaction of AMBRA1 with the dynein motor complex regulates mammalian autophagy

(2010) Sabrina Di Bartolomeo et al.   JOURNAL OF CELL BIOLOGY

FYCO1 is a Rab7 effector that binds to LC3 and PI3P to mediate microtubule plus end–directed vesicle transport

(2010) Serhiy Pankiv et al.   JOURNAL OF CELL BIOLOGY

An Atg9-containing compartment that functions in the early steps of autophagosome biogenesis

(2010) Muriel Mari et al.   JOURNAL OF CELL BIOLOGY

The conserved oligomeric Golgi complex is involved in double-membrane vesicle formation during autophagy

(2010) Wei-Lien Yen et al.   JOURNAL OF CELL BIOLOGY

Endogenous HMGB1 regulates autophagy

(2010) Daolin Tang et al.   JOURNAL OF CELL BIOLOGY

Autophagy requires endoplasmic reticulum targeting of the PI3-kinase complex via Atg14L

(2010) Kohichi Matsunaga et al.   JOURNAL OF CELL BIOLOGY

Atg8 regulates vacuolar membrane dynamics in a lipidation-independent manner in Pichia pastoris

(2010) Naoki Tamura et al.   JOURNAL OF CELL SCIENCE

Altered Autophagy in Human Adipose Tissues in Obesity

(2010) Julia Kovsan et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Autophagy influences glomerular disease susceptibility and maintains podocyte homeostasis in aging mice

(2010) Björn Hartleben et al.   JOURNAL OF CLINICAL INVESTIGATION

Induction of autophagy-dependent necroptosis is required for childhood acute lymphoblastic leukemia cells to overcome glucocorticoid resistance

(2010) Laura Bonapace et al.   JOURNAL OF CLINICAL INVESTIGATION

Prognostic relevance of light chain 3 (LC3A) autophagy patterns in colorectal adenocarcinomas

(2010) A. Giatromanolaki et al.   JOURNAL OF CLINICAL PATHOLOGY

Monolayer behavior of binary systems of betulinic acid and cardiolipin: Thermodynamic analyses of Langmuir monolayers and AFM study of Langmuir–Blodgett monolayers

(2010) Yingying Chen et al.   JOURNAL OF COLLOID AND INTERFACE SCIENCE

Atg9A Protein, an Autophagy-related Membrane Protein, Is Localized in the Neurons of Mouse Brains

(2010) Hirosumi Tamura et al.   JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY

A functional analysis of GABARAP on 17p13.1 by knockdown zebrafish

(2010) Yuta Komoike et al.   JOURNAL OF HUMAN GENETICS

Identification of an Autophagy Defect in Smokers' Alveolar Macrophages

(2010) M. M. Monick et al.   JOURNAL OF IMMUNOLOGY

Pathogenic Lysosomal Depletion in Parkinson's Disease

(2010) B. Dehay et al.   JOURNAL OF NEUROSCIENCE

Autophagy: assays and artifacts

(2010) Sandra Barth et al.   JOURNAL OF PATHOLOGY

Melatonin protects against apoptotic and autophagic cell death in C2C12 murine myoblast cells

(2010) Chi Hyun Kim et al.   JOURNAL OF PINEAL RESEARCH

Coomassie Staining as Loading Control in Western Blot Analysis

(2010) Charlotte Welinder et al.   JOURNAL OF PROTEOME RESEARCH

Coxsackievirus Infection Induces Autophagy-Like Vesicles and Megaphagosomes in Pancreatic Acinar Cells In Vivo

(2010) C. C. Kemball et al.   JOURNAL OF VIROLOGY

Autophagy-active beclin-1 correlates with favourable clinical outcome in non-Hodgkin lymphomas

(2010) Giuseppina Nicotra et al.   MODERN PATHOLOGY

Deficiency of the Transcriptional Regulator p8 Results in Increased Autophagy and Apoptosis, and Causes Impaired Heart Function

(2010) Derek K. Kong et al.   MOLECULAR BIOLOGY OF THE CELL

Post-Golgi Sec Proteins Are Required for Autophagy in Saccharomyces cerevisiae

(2010) Jiefei Geng et al.   MOLECULAR BIOLOGY OF THE CELL

Growth Factor erv1-like Modulates Drp1 to Preserve Mitochondrial Dynamics and Function in Mouse Embryonic Stem Cells

(2010) Lance R. Todd et al.   MOLECULAR BIOLOGY OF THE CELL

Combinational Soluble N-Ethylmaleimide-sensitive Factor Attachment Protein Receptor Proteins VAMP8 and Vti1b Mediate Fusion of Antimicrobial and Canonical Autophagosomes with Lysosomes

(2010) Nobumichi Furuta et al.   MOLECULAR BIOLOGY OF THE CELL

A Ral GAP complex links PI 3-kinase/Akt signaling to RalA activation in insulin action

(2010) Xiao-Wei Chen et al.   MOLECULAR BIOLOGY OF THE CELL

ISG20L1 is a p53 family target gene that modulates genotoxic stress-induced autophagy

(2010) Kathryn G Eby et al.   Molecular Cancer

Negative Regulation of Vps34 by Cdk Mediated Phosphorylation

(2010) Tsuyoshi Furuya et al.   MOLECULAR CELL

The Selective Macroautophagic Degradation of Aggregated Proteins Requires the PI3P-Binding Protein Alfy

(2010) Maria Filimonenko et al.   MOLECULAR CELL

Positive or Negative Roles of Different Cyclin-Dependent Kinase Pho85-Cyclin Complexes Orchestrate Induction of Autophagy in Saccharomyces cerevisiae

(2010) Zhifen Yang et al.   MOLECULAR CELL

Identification of Regulators of Chaperone-Mediated Autophagy

(2010) Urmi Bandyopadhyay et al.   MOLECULAR CELL

Structure of the Human mTOR Complex I and Its Implications for Rapamycin Inhibition

(2010) Calvin K. Yip et al.   MOLECULAR CELL

Unknown

(2010) Anita Ost et al.   MOLECULAR MEDICINE

The molecular mechanism of mitochondria autophagy in yeast

(2010) Tomotake Kanki et al.   MOLECULAR MICROBIOLOGY

The autophagy genes atg8 and atg1 affect morphogenesis and pathogenicity in Ustilago maydis

(2010) MARINA NADAL et al.   MOLECULAR PLANT PATHOLOGY

C60(Nd) nanoparticles enhance chemotherapeutic susceptibility of cancer cells by modulation of autophagy

(2010) Pengfei Wei et al.   NANOTECHNOLOGY

Activation of autophagy during cell death requires the engulfment receptor Draper

(2010) Christina K. McPhee et al.   NATURE

Network organization of the human autophagy system

(2010) Christian Behrends et al.   NATURE

Termination of autophagy and reformation of lysosomes regulated by mTOR

(2010) Li Yu et al.   NATURE

Autophagy in mammalian development and differentiation

(2010) Noboru Mizushima et al.   NATURE CELL BIOLOGY

The selective autophagy substrate p62 activates the stress responsive transcription factor Nrf2 through inactivation of Keap1

(2010) Masaaki Komatsu et al.   NATURE CELL BIOLOGY

Plasma membrane contributes to the formation of pre-autophagosomal structures

(2010) Brinda Ravikumar et al.   NATURE CELL BIOLOGY

Cytosolic FoxO1 is essential for the induction of autophagy and tumour suppressor activity

(2010) Ying Zhao et al.   NATURE CELL BIOLOGY

PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1

(2010) Sven Geisler et al.   NATURE CELL BIOLOGY

Chemical modulators of autophagy as biological probes and potential therapeutics

(2010) Angeleen Fleming et al.   Nature Chemical Biology

Autophagy is defective in collagen VI muscular dystrophies and its reactivation rescues myofiber degeneration

(2010) Paolo Grumati et al.   NATURE MEDICINE

Trehalose ameliorates dopaminergic and tau pathology in parkin deleted/tau overexpressing mice through autophagy activation

(2010) Jose A. Rodríguez-Navarro et al.   NEUROBIOLOGY OF DISEASE

Light induced retinal degeneration activates a caspase-independent pathway involving cathepsin D

(2010) Sabine Chahory et al.   NEUROCHEMISTRY INTERNATIONAL

Snapin-Regulated Late Endosomal Transport Is Critical for Efficient Autophagy-Lysosomal Function in Neurons

(2010) Qian Cai et al.   NEURON

The Autophagy Database: an all-inclusive information resource on autophagy that provides nourishment for research

(2010) K. Homma et al.   NUCLEIC ACIDS RESEARCH

Regulation of autophagy by ATF4 in response to severe hypoxia

(2010) T Rzymski et al.   ONCOGENE

HMGB1 release and redox regulates autophagy and apoptosis in cancer cells

(2010) D Tang et al.   ONCOGENE

Autophagy in unicellular eukaryotes

(2010) J. A. K. W. Kiel   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Fluorescent Proteins and Their Applications in Imaging Living Cells and Tissues

(2010) Dmitriy M. Chudakov et al.   PHYSIOLOGICAL REVIEWS

ATG8 lipidation and ATG8-mediated autophagy in Arabidopsis require ATG12 expressed from the differentially controlled ATG12A AND ATG12B loci

(2010) Taijoon Chung et al.   PLANT JOURNAL

Inhibition of Target of Rapamycin Signaling and Stress Activate Autophagy in Chlamydomonas reinhardtii

(2010) M. E. Perez-Perez et al.   PLANT PHYSIOLOGY

Loss of ALS2/Alsin Exacerbates Motor Dysfunction in a SOD1H46R-Expressing Mouse ALS Model by Disturbing Endolysosomal Trafficking

(2010) Shinji Hadano et al.   PLoS One

Macroautophagy-Mediated Degradation of Whole Nuclei in the Filamentous Fungus Aspergillus oryzae

(2010) Jun-ya Shoji et al.   PLoS One

Astrocyte elevated gene-1 induces protective autophagy

(2010) S. K. Bhutia et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A small-molecule scaffold induces autophagy in primary neurons and protects against toxicity in a Huntington disease model

(2010) A. S. Tsvetkov et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Deletion of TDP-43 down-regulates Tbc1d1, a gene linked to obesity, and alters body fat metabolism

(2010) P.-M. Chiang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

ATM signals to TSC2 in the cytoplasm to regulate mTORC1 in response to ROS

(2010) A. Alexander et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Human leucine-rich repeat proteins: a genome-wide bioinformatic categorization and functional analysis in innate immunity

(2010) A. C. Y. Ng et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Trs85 directs a Ypt1 GEF, TRAPPIII, to the phagophore to promote autophagy

(2010) Molly A. Lynch-Day et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Discovery of drug mode of action and drug repositioning from transcriptional responses

(2010) F. Iorio et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

An Autophagy-Enhancing Drug Promotes Degradation of Mutant  1-Antitrypsin Z and Reduces Hepatic Fibrosis

(2010) T. Hidvegi et al.   SCIENCE

Phosphorylation of ULK1 (hATG1) by AMP-Activated Protein Kinase Connects Energy Sensing to Mitophagy

(2010) D. F. Egan et al.   SCIENCE

Ammonia Derived from Glutaminolysis Is a Diffusible Regulator of Autophagy

(2010) C. H. Eng et al.   Science Signaling

ARD1 Stabilization of TSC2 Suppresses Tumorigenesis Through the mTOR Signaling Pathway

(2010) H.-P. Kuo et al.   Science Signaling

Inhibition of PI3k Class III–Dependent Autophagy Prevents Apoptosis and Necrosis by Oxidative Stress in Dopaminergic Neuroblastoma Cells

(2010) Roberta Castino et al.   TOXICOLOGICAL SCIENCES

Modulation of Local PtdIns3P Levels by the PI Phosphatase MTMR3 Regulates Constitutive Autophagy

(2010) Naoko Taguchi-Atarashi et al.   TRAFFIC

Autophagosome Formation Depends on the Small GTPase Rab1 and Functional ER Exit Sites

(2010) Felipe Carlos Martín Zoppino et al.   TRAFFIC

The Beclin 1–VPS34 complex – at the crossroads of autophagy and beyond

(2010) Sarah F. Funderburk et al.   TRENDS IN CELL BIOLOGY

Caloric restriction and resveratrol promote longevity through the Sirtuin-1-dependent induction of autophagy

(2010) E Morselli et al.   Cell Death & Disease

Beclin 1 cleavage by caspase-3 inactivates autophagy and promotes apoptosis

(2010) Yushan Zhu et al.   Protein & Cell

p62/SQSTM1 is overexpressed and prominently accumulated in inclusions of sporadic inclusion-body myositis muscle fibers, and can help differentiating it from polymyositis and dermatomyositis

(2009) Anna Nogalska et al.   ACTA NEUROPATHOLOGICA

Increased Activity and Altered Subcellular Distribution of Lysosomal Enzymes Determine Neuronal Vulnerability in Niemann-Pick Type C1-Deficient Mice

(2009) Asha Amritraj et al.   AMERICAN JOURNAL OF PATHOLOGY

Enhancement of Autophagic Flux after Neonatal Cerebral Hypoxia-Ischemia and Its Region-Specific Relationship to Apoptotic Mechanisms

(2009) Vanessa Ginet et al.   AMERICAN JOURNAL OF PATHOLOGY

Postischemic treatment of neonatal cerebral ischemia should target autophagy

(2009) Julien Puyal et al.   ANNALS OF NEUROLOGY

Genome-Wide Identification of Saccharomyces cerevisiae Genes Required for Maximal Tolerance to Ethanol

(2009) M. C. Teixeira et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Mutations for Gaucher Disease Confer High Susceptibility to Parkinson Disease

(2009) Jun Mitsui et al.   ARCHIVES OF NEUROLOGY

Radiation-induced autophagy in normal and cancer cells: Towards novel cytoprotection and radio-sensitization policies?

(2009) Christos E. Zois et al.   Autophagy

Autophagy-assisted glycogen catabolism regulates asexual differentiation inMagnaporthe oryzae

(2009) Yi Zhen Deng et al.   Autophagy

Prognostic significance of Beclin 1-dependent apoptotic activity in hepatocellular carcinoma

(2009) Ying-Hong Shi et al.   Autophagy

Transglutaminase 2 is involved in autophagosome maturation

(2009) Manuela D'Eletto et al.   Autophagy

Autophagy is not universally required for phosphatidyl-serine exposure and apoptotic cell engulfment during neural development

(2009) María A. Mellén et al.   Autophagy

A combined proteomic and genetic analysis identifies a role for the lipid desaturase Desat1 in starvation-induced autophagy in Drosophila

(2009) Katja Köhler et al.   Autophagy

An executioner caspase regulates autophagy

(2009) Y.C. Claire Hou et al.   Autophagy

Quantitation of selective autophagic protein aggregate degradation in vitro and in vivo using luciferase reporters

(2009) Jeong-Sun Ju et al.   Autophagy

Dual roles for autophagy during follicular atresia in fish ovary

(2009) Ralph G. Thomé et al.   Autophagy

Autophagy as the main means of cytotoxicity by glucocorticoids in hematological malignancies

(2009) Dan Grandér et al.   Autophagy

Methodological considerations for assessing autophagy modulators: A study with calcium phosphate precipitates

(2009) Sovan Sarkar et al.   Autophagy

TRB3 links ER stress to autophagy in cannabinoid antitumoral action

(2009) María Salazar et al.   Autophagy

To die or to live: the dual role of poly(ADP-ribose) polymerase-1 in autophagy and necrosis under oxidative stress and DNA damage

(2009) Qing Huang et al.   Autophagy

Nix directly binds to GABARAP: A possible crosstalk between apoptosis and autophagy

(2009) Melanie Schwarten et al.   Autophagy

Indirect estimation of the area density of Atg8 on the phagophore

(2009) Zhiping Xie et al.   Autophagy

Measuring piecemeal microautophagy of the nucleus inSaccharomyces cerevisiae

(2009) Jonathan I. Millen et al.   Autophagy

Autophagy is an important event for megakaryocytic differentiation of the chronic myelogenous leukemia K562 cell line

(2009) Pascal Colosetti et al.   Autophagy

Autophagy in food biotechnology

(2009) Hagai Abeliovich et al.   Autophagy

Identification of novel autophagy regulators by a luciferase-based assay for the kinetics of autophagic flux

(2009) Thomas Farkas et al.   Autophagy

Monitoring mitophagy in yeast: The Om45-GFP processing assay

(2009) Tomotake Kanki et al.   Autophagy

A novel, human Atg13 binding protein, Atg101, interacts with ULK1 and is essential for macroautophagy

(2009) Carol A. Mercer et al.   Autophagy

The prognostic role of Beclin 1 protein expression in high-grade gliomas

(2009) Luigi Pirtoli et al.   Autophagy

epg-1functions in autophagy-regulated processes and may encode a highly divergent Atg13 homolog inC. elegans

(2009) E Tian et al.   Autophagy

Ceramide-induced autophagy: To junk or to protect cells?

(2009) Sophie Pattingre et al.   Autophagy

Cell death: A dynamic response concept

(2009) Benjamin Loos et al.   Autophagy

Piecemeal microautophagy of the nucleus: Genetic and morphological traits

(2009) Roswitha Krick et al.   Autophagy

The expression ofbeclin 1is associated with favorable prognosis in stage IIIB colon cancers

(2009) Bao-Xiu Li et al.   Autophagy

PARP-1 is involved in autophagy induced by DNA damage

(2009) José Antonio Muñoz-Gámez et al.   Autophagy

In search of an “autophagomometer”

(2009) David C. Rubinsztein et al.   Autophagy

Assaying autophagic activity in transgenic GFP-Lc3 and GFP-Gabarap zebrafish embryos

(2009) Congcong He et al.   Autophagy

High-throughput functional screening for autophagy-related genes and identification ofTM9SF1as an autophagosome-inducing gene

(2009) Pengfei He et al.   Autophagy

3D tomography reveals connections between the phagophore and endoplasmic reticulum

(2009) Päivi Ylä-Anttila et al.   Autophagy

Basal autophagy induction without AMP-activated protein kinase under low glucose conditions

(2009) Tyisha Williams et al.   Autophagy

Atg101, a novel mammalian autophagy protein interacting with Atg13

(2009) Nao Hosokawa et al.   Autophagy

Cardioprotection requires taking out the trash

(2009) Roberta A. Gottlieb et al.   BASIC RESEARCH IN CARDIOLOGY

The MAP1-LC3 conjugation system is involved in lipid droplet formation

(2009) Masahiro Shibata et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Inhibition of macroautophagy by bafilomycin A1 lowers proliferation and induces apoptosis in colon cancer cells

(2009) Ya Chun Wu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Ku-0063794 is a specific inhibitor of the mammalian target of rapamycin (mTOR)

(2009) Juan M. García-Martínez et al.   BIOCHEMICAL JOURNAL

Autophagy in Hydra: A response to starvation and stress in early animal evolution

(2009) Simona Chera et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

TI-VAMP/VAMP7 and VAMP3/cellubrevin: two v-SNARE proteins involved in specific steps of the autophagy/multivesicular body pathways

(2009) Claudio Marcelo Fader et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

ANCHOR: web server for predicting protein binding regions in disordered proteins

(2009) Z. Dosztanyi et al.   BIOINFORMATICS

Systematic cloning and analysis of autophagy-related genes from the silkworm Bombyx mori

(2009) Xuan Zhang et al.   BMC MOLECULAR BIOLOGY

Targeted Activation of Innate Immunity for Therapeutic Induction of Autophagy and Apoptosis in Melanoma Cells

(2009) Damià Tormo et al.   CANCER CELL

The drs tumor suppressor is involved in the maturation process of autophagy induced by low serum

(2009) Yukihiro Tambe et al.   CANCER LETTERS

AZD8055 Is a Potent, Selective, and Orally Bioavailable ATP-Competitive Mammalian Target of Rapamycin Kinase Inhibitor with In vitro and In vivo Antitumor Activity

(2009) C. M. Chresta et al.   CANCER RESEARCH

Biochemical, Cellular, and In vivo Activity of Novel ATP-Competitive and Selective Inhibitors of the Mammalian Target of Rapamycin

(2009) K. Yu et al.   CANCER RESEARCH

Autophagic Components Contribute to Hypersensitive Cell Death in Arabidopsis

(2009) Daniel Hofius et al.   CELL

SEPA-1 Mediates the Specific Recognition and Degradation of P Granule Components by Autophagy in C. elegans

(2009) Yuxia Zhang et al.   CELL

Bidirectional Transport of Amino Acids Regulates mTOR and Autophagy

(2009) Paul Nicklin et al.   CELL

DEPTOR Is an mTOR Inhibitor Frequently Overexpressed in Multiple Myeloma Cells and Required for Their Survival

(2009) Timothy R. Peterson et al.   CELL

p62 at the Crossroads of Autophagy, Apoptosis, and Cancer

(2009) Jorge Moscat et al.   CELL

Modes of cell death in the pupal perivisceral fat body tissue of the silkworm Bombyx mori L.

(2009) Purushothaman Sumithra et al.   CELL AND TISSUE RESEARCH

Role of FK506-binding protein 51 in the control of apoptosis of irradiated melanoma cells

(2009) S Romano et al.   CELL DEATH AND DIFFERENTIATION

Ligands of the antiestrogen-binding site induce active cell death and autophagy in human breast cancer cells through the modulation of cholesterol metabolism

(2009) P de Medina et al.   CELL DEATH AND DIFFERENTIATION

p38α blockade inhibits colorectal cancer growth in vivo by inducing a switch from HIF1α- to FoxO-dependent transcription

(2009) F Chiacchiera et al.   CELL DEATH AND DIFFERENTIATION

The inositol 1,4,5-trisphosphate receptor regulates autophagy through its interaction with Beclin 1

(2009) J M Vicencio et al.   CELL DEATH AND DIFFERENTIATION

Guidelines for the use and interpretation of assays for monitoring cell death in higher eukaryotes

(2009) L Galluzzi et al.   CELL DEATH AND DIFFERENTIATION

Apoptosis blocks Beclin 1-dependent autophagosome synthesis: an effect rescued by Bcl-xL

(2009) S Luo et al.   CELL DEATH AND DIFFERENTIATION

Autophagy, Immunity, and Microbial Adaptations

(2009) Vojo Deretic et al.   Cell Host & Microbe

Shigella Phagocytic Vacuolar Membrane Remnants Participate in the Cellular Response to Pathogen Invasion and Are Regulated by Autophagy

(2009) Nicolas Dupont et al.   Cell Host & Microbe

Matrix Protein 2 of Influenza A Virus Blocks Autophagosome Fusion with Lysosomes

(2009) Monique Gannagé et al.   Cell Host & Microbe

Autophagy Induction by the Pathogen Receptor CD46

(2009) Pierre-Emmanuel Joubert et al.   Cell Host & Microbe

C. elegans Major Fats Are Stored in Vesicles Distinct from Lysosome-Related Organelles

(2009) Eyleen J. O'Rourke et al.   Cell Metabolism

Autophagy Is Required to Maintain Muscle Mass

(2009) Eva Masiero et al.   Cell Metabolism

A small GTPase, human Rab32, is required for the formation of autophagic vacuoles under basal conditions

(2009) Yuko Hirota et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Autophagy supportsCandida glabratasurvival during phagocytosis

(2009) Andreas Roetzer et al.   CELLULAR MICROBIOLOGY

Autophagy, Not Apoptosis, Is Essential for Midgut Cell Death in Drosophila

(2009) Donna Denton et al.   CURRENT BIOLOGY

Turnover of organelles by autophagy in yeast

(2009) Jean-Claude Farré et al.   CURRENT OPINION IN CELL BIOLOGY

Vps-C complexes: gatekeepers of endolysosomal traffic

(2009) Daniel P Nickerson et al.   CURRENT OPINION IN CELL BIOLOGY

Mammalian autophagy: core molecular machinery and signaling regulation

(2009) Zhifen Yang et al.   CURRENT OPINION IN CELL BIOLOGY

Atg32 Is a Mitochondrial Protein that Confers Selectivity during Mitophagy

(2009) Tomotake Kanki et al.   DEVELOPMENTAL CELL

Mitochondria-Anchored Receptor Atg32 Mediates Degradation of Mitochondria via Selective Autophagy

(2009) Koji Okamoto et al.   DEVELOPMENTAL CELL

Posttranslational regulation of BCL2 levels in cerebellar granule cells: A mechanism of neuronal survival

(2009) Laura Lossi et al.   Developmental Neurobiology

Autophagy in human type 2 diabetes pancreatic beta cells

(2009) M. Masini et al.   DIABETOLOGIA

Quantifying Western blots: Pitfalls of densitometry

(2009) Max Gassmann et al.   ELECTROPHORESIS

Protein quality control during aging involves recruitment of the macroautophagy pathway by BAG3

(2009) Martin Gamerdinger et al.   EMBO JOURNAL

Control of autophagy initiation by phosphoinositide 3-phosphatase jumpy

(2009) Isabelle Vergne et al.   EMBO JOURNAL

Coordinated regulation of autophagy by p38α MAPK through mAtg9 and p38IP

(2009) Jemma L Webber et al.   EMBO JOURNAL

TAK1 activates AMPK-dependent cytoprotective autophagy in TRAIL-treated epithelial cells

(2009) Griselda Herrero-Martín et al.   EMBO JOURNAL

Modulation of intracellular ROS levels by TIGAR controls autophagy

(2009) Karim Bensaad et al.   EMBO JOURNAL

The IKK complex contributes to the induction of autophagy

(2009) Alfredo Criollo et al.   EMBO JOURNAL

Antagonism of Beclin 1-dependent autophagy by BCL-2 at the endoplasmic reticulum requires NAF-1

(2009) Natasha C Chang et al.   EMBO JOURNAL

PLIC proteins or ubiquilins regulate autophagy-dependent cell survival during nutrient starvation

(2009) Elsa-Noah N'Diaye et al.   EMBO REPORTS

The nuclear cofactor DOR regulates autophagy in mammalian and Drosophila cells

(2009) Caroline Mauvezin et al.   EMBO REPORTS

Nix is a selective autophagy receptor for mitochondrial clearance

(2009) Ivana Novak et al.   EMBO REPORTS

DAP-kinase-mediated phosphorylation on the BH3 domain of beclin 1 promotes dissociation of beclin 1 from Bcl-XL and induction of autophagy

(2009) Einat Zalckvar et al.   EMBO REPORTS

Identification of a novel serine/threonine kinase ULK3 as a positive regulator of Hedgehog pathway

(2009) Alla Maloverjan et al.   EXPERIMENTAL CELL RESEARCH

Mechanisms of cross-talk between the ubiquitin-proteasome and autophagy-lysosome systems

(2009) Viktor I. Korolchuk et al.   FEBS LETTERS

Dynamics of the yeast transcriptome during wine fermentation reveals a novel fermentation stress response

(2009) Virginia D. Marks et al.   FEMS YEAST RESEARCH

SmATG7 is required for viability in the homothallic ascomycete Sordaria macrospora

(2009) Nicole Nolting et al.   FUNGAL GENETICS AND BIOLOGY

Cisd2 deficiency drives premature aging and causes mitochondria-mediated defects in mice

(2009) Y.-F. Chen et al.   GENES & DEVELOPMENT

Autophagy mediates the mitotic senescence transition

(2009) A. R.J. Young et al.   GENES & DEVELOPMENT

Lag-phase autophagy in the methylotrophic yeastPichia pastoris

(2009) Shun-ichi Yamashita et al.   GENES TO CELLS

Functional interaction of mammalian target of rapamycin complexes in regulating mammalian cell size and cell cycle

(2009) M. Rosner et al.   HUMAN MOLECULAR GENETICS

LRRK2 regulates autophagic activity and localizes to specific membrane microdomains in a novel human genomic reporter cellular model

(2009) Javier Alegre-Abarrategui et al.   HUMAN MOLECULAR GENETICS

Autophagy Is an Essential Component of Drosophila Immunity against Vesicular Stomatitis Virus

(2009) Spencer Shelly et al.   IMMUNITY

Hepatic Autophagy Is Suppressed in the Presence of Insulin Resistance and Hyperinsulinemia

(2009) Hui-Yu Liu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Vacuole Import and Degradation Pathway Utilizes Early Steps of Endocytosis and Actin Polymerization to Deliver Cargo Proteins to the Vacuole for Degradation

(2009) C. Randell Brown et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Aup1-mediated Regulation of Rtg3 during Mitophagy

(2009) Dikla Journo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Tuberous Sclerosis Tumor Suppressor Complex-like Complexes Act as GTPase-activating Proteins for Ral GTPases

(2009) Ryutaro Shirakawa et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Regulation of Autophagy by the p300 Acetyltransferase

(2009) In Hye Lee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Biochemical Isolation and Characterization of the Tubulovesicular LC3-positive Autophagosomal Compartment

(2009) Wentao Gao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Loss of PINK1 Function Promotes Mitophagy through Effects on Oxidative Stress and Mitochondrial Fission

(2009) Ruben K. Dagda et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

ULK1·ATG13·FIP200 Complex Mediates mTOR Signaling and Is Essential for Autophagy

(2009) Ian G. Ganley et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

An ATP-competitive Mammalian Target of Rapamycin Inhibitor Reveals Rapamycin-resistant Functions of mTORC1

(2009) Carson C. Thoreen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Coordination of membrane events during autophagy by multiple class III PI3-kinase complexes

(2009) Anne Simonsen et al.   JOURNAL OF CELL BIOLOGY

Valosin-containing protein (VCP) is required for autophagy and is disrupted in VCP disease

(2009) Jeong-Sun Ju et al.   JOURNAL OF CELL BIOLOGY

Autophagy pathway intersects with HIV-1 biosynthesis and regulates viral yields in macrophages

(2009) George B. Kyei et al.   JOURNAL OF CELL BIOLOGY

Chaperone-mediated autophagy is defective in mucolipidosis type IV

(2009) Bhuvarahamurthy Venugopal et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Cannabinoid action induces autophagy-mediated cell death through stimulation of ER stress in human glioma cells

(2009) María Salazar et al.   JOURNAL OF CLINICAL INVESTIGATION

The unfolded protein response protects human tumor cells during hypoxia through regulation of the autophagy genes MAP1LC3B and ATG5

(2009) Kasper M.A. Rouschop et al.   JOURNAL OF CLINICAL INVESTIGATION

Concurrent induction of necrosis, apoptosis, and autophagy in ischemic preconditioned human livers formerly treated by chemotherapy

(2009) Marie-Charlotte Domart et al.   JOURNAL OF HEPATOLOGY

A Novel Hybrid Yeast-Human Network Analysis Reveals an Essential Role for FNBP1L in Antibacterial Autophagy

(2009) A. Huett et al.   JOURNAL OF IMMUNOLOGY

The Adaptor Protein p62/SQSTM1 Targets Invading Bacteria to the Autophagy Pathway

(2009) Y. T. Zheng et al.   JOURNAL OF IMMUNOLOGY

Activation of Mammalian Target of Rapamycin Controls the Loss of TCR  in Lupus T Cells through HRES-1/Rab4-Regulated Lysosomal Degradation

(2009) D. R. Fernandez et al.   JOURNAL OF IMMUNOLOGY

Dimerisation of the UBA Domain of p62 Inhibits Ubiquitin Binding and Regulates NF-κB Signalling

(2009) Jed Long et al.   JOURNAL OF MOLECULAR BIOLOGY

Density functional computational studies on (E)-2-[(2-Hydroxy-5-nitrophenyl)-iminiomethyl]-4-nitrophenolate

(2009) Hasan Tanak et al.   JOURNAL OF MOLECULAR MODELING

HO-1-mediated macroautophagy: a mechanism for unregulated iron deposition in aging and degenerating neural tissues

(2009) Hillel Zukor et al.   JOURNAL OF NEUROCHEMISTRY

Unc-51 Controls Active Zone Density and Protein Composition by Downregulating ERK Signaling

(2009) Y. P. Wairkar et al.   JOURNAL OF NEUROSCIENCE

Mapping the Phosphorylation Sites of Ulk1

(2009) Frank C. Dorsey et al.   JOURNAL OF PROTEOME RESEARCH

Interaction of ICP34.5 with Beclin 1 Modulates Herpes Simplex Virus Type 1 Pathogenesis through Control of CD4+ T-Cell Responses

(2009) D. A. Leib et al.   JOURNAL OF VIROLOGY

Hypoxia-Induced Autophagy Is Mediated through Hypoxia-Inducible Factor Induction of BNIP3 and BNIP3L via Their BH3 Domains

(2009) G. Bellot et al.   MOLECULAR AND CELLULAR BIOLOGY

Tor Directly Controls the Atg1 Kinase Complex To Regulate Autophagy

(2009) Y. Kamada et al.   MOLECULAR AND CELLULAR BIOLOGY

A Genomic Screen for Yeast Mutants Defective in Selective Mitochondria Autophagy

(2009) Tomotake Kanki et al.   MOLECULAR BIOLOGY OF THE CELL

Nutrient-dependent mTORC1 Association with the ULK1–Atg13–FIP200 Complex Required for Autophagy

(2009) Nao Hosokawa et al.   MOLECULAR BIOLOGY OF THE CELL

An Atg1/Atg13 Complex with Multiple Roles in TOR-mediated Autophagy Regulation

(2009) Yu-Yun Chang et al.   MOLECULAR BIOLOGY OF THE CELL

ULK-Atg13-FIP200 Complexes Mediate mTOR Signaling to the Autophagy Machinery

(2009) Chang Hwa Jung et al.   MOLECULAR BIOLOGY OF THE CELL

NVP-BEZ235, a novel dual phosphatidylinositol 3-kinase/mammalian target of rapamycin inhibitor, elicits multifaceted antitumor activities in human gliomas

(2009) T.-J. Liu et al.   MOLECULAR CANCER THERAPEUTICS

KEAP1 E3 Ligase-Mediated Downregulation of NF-κB Signaling by Targeting IKKβ

(2009) Dung-Fang Lee et al.   MOLECULAR CELL

A Small Molecule Inhibitor of Inducible Heat Shock Protein 70

(2009) J. I-Ju Leu et al.   MOLECULAR CELL

Discovering Hematopoietic Mechanisms through Genome-wide Analysis of GATA Factor Chromatin Occupancy

(2009) Tohru Fujiwara et al.   MOLECULAR CELL

Insights into GATA-1-Mediated Gene Activation versus Repression via Genome-wide Chromatin Occupancy Analysis

(2009) Ming Yu et al.   MOLECULAR CELL

Autophagy Inhibition Compromises Degradation of Ubiquitin-Proteasome Pathway Substrates

(2009) Viktor I. Korolchuk et al.   MOLECULAR CELL

A Role for NBR1 in Autophagosomal Degradation of Ubiquitinated Substrates

(2009) Vladimir Kirkin et al.   MOLECULAR CELL

Discovery of Atg5/Atg7-independent alternative macroautophagy

(2009) Yuya Nishida et al.   NATURE

Autophagy regulates lipid metabolism

(2009) Rajat Singh et al.   NATURE

An inhibitor of NEDD8-activating enzyme as a new approach to treat cancer

(2009) Teresa A. Soucy et al.   NATURE

Listeria monocytogenes ActA-mediated escape from autophagic recognition

(2009) Yuko Yoshikawa et al.   NATURE CELL BIOLOGY

FLIP-mediated autophagy regulation in cell death control

(2009) Jong-Soo Lee et al.   NATURE CELL BIOLOGY

Induction of autophagy by spermidine promotes longevity

(2009) Tobias Eisenberg et al.   NATURE CELL BIOLOGY

Distinct regulation of autophagic activity by Atg14L and Rubicon associated with Beclin 1–phosphatidylinositol-3-kinase complex

(2009) Yun Zhong et al.   NATURE CELL BIOLOGY

Two Beclin 1-binding proteins, Atg14L and Rubicon, reciprocally regulate autophagy at different stages

(2009) Kohichi Matsunaga et al.   NATURE CELL BIOLOGY

Autophagy enhances the presentation of endogenous viral antigens on MHC class I molecules during HSV-1 infection

(2009) Luc English et al.   NATURE IMMUNOLOGY

Nod1 and Nod2 direct autophagy by recruiting ATG16L1 to the plasma membrane at the site of bacterial entry

(2009) Leonardo H Travassos et al.   NATURE IMMUNOLOGY

The TBK1 adaptor and autophagy receptor NDP52 restricts the proliferation of ubiquitin-coated bacteria

(2009) Teresa L M Thurston et al.   NATURE IMMUNOLOGY

SUnSET, a nonradioactive method to monitor protein synthesis

(2009) Enrico K Schmidt et al.   NATURE METHODS

Rab GTPases as coordinators of vesicle traffic

(2009) Harald Stenmark   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Multicenter Analysis of Glucocerebrosidase Mutations in Parkinson's Disease

(2009) E. Sidransky et al.   NEW ENGLAND JOURNAL OF MEDICINE

Beclin-1 Expression is a Predictor of Clinical Outcome in Patients with Esophageal Squamous Cell Carcinoma and Correlated to Hypoxia-Inducible Factor (HIF)-1α Expression

(2009) Yongshun Chen et al.   PATHOLOGY & ONCOLOGY RESEARCH

Atg26-Mediated Pexophagy Is Required for Host Invasion by the Plant Pathogenic Fungus Colletotrichum orbiculare

(2009) M. Asakura et al.   PLANT CELL

Screen for Chemical Modulators of Autophagy Reveals Novel Therapeutic Inhibitors of mTORC1 Signaling

(2009) Aruna D. Balgi et al.   PLoS One

The Tor and PKA signaling pathways independently target the Atg1/Atg13 protein kinase complex to control autophagy

(2009) J. S. Stephan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genome-wide functional analysis reveals that infection-associated fungal autophagy is necessary for rice blast disease

(2009) M. J. Kershaw et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Loss of autophagy in erythroid cells leads to defective removal of mitochondria and severe anemia in vivo

(2009) M. Mortensen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Activation of antibacterial autophagy by NADPH oxidases

(2009) J. Huang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

PINK1-dependent recruitment of Parkin to mitochondria in mitophagy

(2009) C. Vives-Bauza et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The autophagy machinery is required to initiate hepatitis C virus replication

(2009) M. Dreux et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cell death and proliferation in acute slices and organotypic cultures of mammalian CNS

(2009) Laura Lossi et al.   PROGRESS IN NEUROBIOLOGY

Resveratrol Induces Mitochondrial Alterations, Autophagy and a Cryptobiosis-like State in Scuticociliates

(2009) Pedro Morais et al.   PROTIST

Microarray gene expression profiling of mouse brain mRNA in a model of lithium treatment

(2009) Albert Chetcuti et al.   PSYCHIATRIC GENETICS

A Gene Network Regulating Lysosomal Biogenesis and Function

(2009) Marco Sardiello et al.   SCIENCE

Endoplasmic reticulum stress in the intestinal epithelium and inflammatory bowel disease

(2009) Arthur Kaser et al.   SEMINARS IN IMMUNOLOGY

Identification and characterization of a novel mouse and human MOPT gene containing MORN-motif protein in testis

(2009) Y-J. Choi et al.   THERIOGENOLOGY

Peroxisome Dynamics in Cultured Mammalian Cells

(2009) Sofie J. Huybrechts et al.   TRAFFIC

Chaperone-mediated autophagy: selectivity pays off

(2009) Ana Maria Cuervo   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Active-Site Inhibitors of mTOR Target Rapamycin-Resistant Outputs of mTORC1 and mTORC2

(2009) Morris E Feldman et al.   PLOS BIOLOGY

Atg5-Independent Sequestration of Ubiquitinated Mycobacteria

(2009) Cathleen A. Collins et al.   PLoS Pathogens

Disruption of the Toxoplasma gondii Parasitophorous Vacuole by IFNγ-Inducible Immunity-Related GTPases (IRG Proteins) Triggers Necrotic Cell Death

(2009) Yang O. Zhao et al.   PLoS Pathogens

Inhibition of Autophagy Prevents Hippocampal Pyramidal Neuron Death after Hypoxic-Ischemic Injury

(2008) Masato Koike et al.   AMERICAN JOURNAL OF PATHOLOGY

An in vivo and in vitro assessment of TOR signaling cascade in rainbow trout (Oncorhynchus mykiss)

(2008) Iban Seiliez et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Age-related differences in oxidative protein-damage in young and senescent fibroblasts

(2008) Tobias Jung et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Glucocerebrosidase Gene Mutations

(2008) Ignacio F. Mata et al.   ARCHIVES OF NEUROLOGY

Role of AMP-activated protein kinase in autophagy and proteasome function

(2008) Rosa Viana et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

TMEM74, a lysosome and autophagosome protein, regulates autophagy

(2008) Chuanfei Yu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Segregation and rapid turnover of EDEM1 by an autophagy-like mechanism modulates standard ERAD and folding activities

(2008) Tito Calì et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Novel mechanism of elimination of malfunctioning mitochondria (mitoptosis): Formation of mitoptotic bodies and extrusion of mitochondrial material from the cell

(2008) Konstantin G. Lyamzaev et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Leukocyte Elastase Inhibitor, the precursor of L-DNase II, inhibits apoptosis by interfering with caspase-8 activation

(2008) Laura Padrón-Barthe et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Autophagic cell death: Analysis in Dictyostelium

(2008) Corinne Giusti et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Ulk1 plays a critical role in the autophagic clearance of mitochondria and ribosomes during reticulocyte maturation

(2008) M. Kundu et al.   BLOOD

Differential gene expression of the honey bee Apis mellifera associated with Varroa destructor infection

(2008) M Navajas et al.   BMC GENOMICS

Macroautophagy inhibition sensitizes tamoxifen-resistant breast cancer cells and enhances mitochondrial depolarization

(2008) M. A. Qadir et al.   BREAST CANCER RESEARCH AND TREATMENT

Interactions between cell death induced by statins and 7-ketocholesterol in rabbit aorta smooth muscle cells

(2008) W Martinet et al.   BRITISH JOURNAL OF PHARMACOLOGY

Diet, Autophagy, and Cancer: A Review

(2008) K. Singletary et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

Mammalian Target of Rapamycin and S6 Kinase 1 Positively Regulate 6-thioguanine-Induced Autophagy

(2008) X. Zeng et al.   CANCER RESEARCH

NVP-BEZ235, a Dual PI3K/mTOR Inhibitor, Prevents PI3K Signaling and Inhibits the Growth of Cancer Cells with Activating PI3K Mutations

(2008) V. Serra et al.   CANCER RESEARCH

Association of Autophagy Defect with a Malignant Phenotype and Poor Prognosis of Hepatocellular Carcinoma

(2008) Z.-B. Ding et al.   CANCER RESEARCH

Blocked Autophagy Sensitizes Resistant Carcinoma Cells to Radiation Therapy

(2008) A. Apel et al.   CANCER RESEARCH

Enhancer of zeste homolog 2 downregulates E-cadherin by mediating histone H3 methylation in gastric cancer cells

(2008) Satoshi Fujii et al.   CANCER SCIENCE

Ubiquitin Chain Editing Revealed by Polyubiquitin Linkage-Specific Antibodies

(2008) Kim Newton et al.   CELL

Identification of a Molecular Signaling Network that Regulates a Cellular Necrotic Cell Death Pathway

(2008) Junichi Hitomi et al.   CELL

p53 Target Genes Sestrin1 and Sestrin2 Connect Genotoxic Stress and mTOR Signaling

(2008) Andrei V. Budanov et al.   CELL

Relationship among follicular apoptosis, integrin β1 and collagen type IV during early ovarian regression in the teleost Prochilodus argenteus after induced spawning

(2008) H. B. Santos et al.   CELL AND TISSUE RESEARCH

The autophagic machinery is necessary for removal of cell corpses from the developing retinal neuroepithelium

(2008) M A Mellén et al.   CELL DEATH AND DIFFERENTIATION

Autophagy regulates selective HMGB1 release in tumor cells that are destined to die

(2008) J Thorburn et al.   CELL DEATH AND DIFFERENTIATION

The unfolded protein response regulator GRP78/BiP is required for endoplasmic reticulum integrity and stress-induced autophagy in mammalian cells

(2008) J Li et al.   CELL DEATH AND DIFFERENTIATION

Role of non-canonical Beclin 1-independent autophagy in cell death induced by resveratrol in human breast cancer cells

(2008) F Scarlatti et al.   CELL DEATH AND DIFFERENTIATION

Function and structure of inherently disordered proteins

(2008) A Keith Dunker et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

PpAtg30 Tags Peroxisomes for Turnover by Selective Autophagy

(2008) Jean-Claude Farré et al.   DEVELOPMENTAL CELL

Toll-like receptors control autophagy

(2008) Mónica A Delgado et al.   EMBO JOURNAL

Metabolic diversification of cells during the development of yeast colonies

(2008) Libuše Váchová et al.   ENVIRONMENTAL MICROBIOLOGY

IGF-I, EGF, and sex steroids regulate autophagy in bovine mammary epithelial cells via the mTOR pathway

(2008) Agnieszka Sobolewska et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

Williams–Beuren syndrome TRIM50 encodes an E3 ubiquitin ligase

(2008) Lucia Micale et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

The peroxin Pex14p is involved in LC3-dependent degradation of mammalian peroxisomes

(2008) Sayuri Hara-Kuge et al.   EXPERIMENTAL CELL RESEARCH

Comprehensive phenotypic analysis for identification of genes affecting growth under ethanol stress inSaccharomyces cerevisiae

(2008) Katsunori Yoshikawa et al.   FEMS YEAST RESEARCH

Autophagy in filamentous fungi

(2008) J POLLACK et al.   FUNGAL GENETICS AND BIOLOGY

The ATG12-Conjugating Enzyme ATG10 Is Essential for Autophagic Vesicle Formation in Arabidopsis thaliana

(2008) A. R. Phillips et al.   GENETICS

Toll-like receptor signaling in the lysosomal pathways

(2008) Miguel A. Sanjuan et al.   IMMUNOLOGICAL REVIEWS

HAMLET (human α-lactalbumin made lethal to tumor cells) triggers autophagic tumor cell death

(2008) Sonja Aits et al.   INTERNATIONAL JOURNAL OF CANCER

Resveratrol: One molecule, many targets

(2008) Luciano Pirola et al.   IUBMB LIFE

What controls TOR?

(2008) Estela Jacinto   IUBMB LIFE

The Vacuolar Import and Degradation Pathway Merges with the Endocytic Pathway to Deliver Fructose-1,6-bisphosphatase to the Vacuole for Degradation

(2008) C. Randell Brown et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Aberrant Interaction between Parkinson Disease-associated Mutant UCH-L1 and the Lysosomal Receptor for Chaperone-mediated Autophagy

(2008) Tomohiro Kabuta et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Small Molecule Inhibitor of Isoprenylcysteine Carboxymethyltransferase Induces Autophagic Cell Death in PC3 Prostate Cancer Cells

(2008) Mei Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mitophagy in Yeast Occurs through a Selective Mechanism

(2008) Tomotake Kanki et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural Basis for Sorting Mechanism of p62 in Selective Autophagy

(2008) Yoshinobu Ichimura et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Ref(2)P, theDrosophila melanogasterhomologue of mammalian p62, is required for the formation of protein aggregates in adult brain

(2008) Ioannis P. Nezis et al.   JOURNAL OF CELL BIOLOGY

The class III PI(3)K Vps34 promotes autophagy and endocytosis but not TOR signaling inDrosophila

(2008) Gábor Juhász et al.   JOURNAL OF CELL BIOLOGY

Effector caspase Dcp-1 and IAP protein Bruce regulate starvation-induced autophagy duringDrosophila melanogasteroogenesis

(2008) Ying-Chen Claire Hou et al.   JOURNAL OF CELL BIOLOGY

Autophagosome formation from membrane compartments enriched in phosphatidylinositol 3-phosphate and dynamically connected to the endoplasmic reticulum

(2008) Elizabeth L. Axe et al.   JOURNAL OF CELL BIOLOGY

Quantitative analysis of autophagy-related protein stoichiometry by fluorescence microscopy

(2008) Jiefei Geng et al.   JOURNAL OF CELL BIOLOGY

Akt inhibition promotes autophagy and sensitizes PTEN-null tumors to lysosomotropic agents

(2008) Michael Degtyarev et al.   JOURNAL OF CELL BIOLOGY

Parkin is recruited selectively to impaired mitochondria and promotes their autophagy

(2008) Derek Narendra et al.   JOURNAL OF CELL BIOLOGY

FIP200, a ULK-interacting protein, is required for autophagosome formation in mammalian cells

(2008) Taichi Hara et al.   JOURNAL OF CELL BIOLOGY

Crosstalk between Hsp70 molecular chaperone, lysosomes and proteasomes in autophagy-mediated proteolysis in human retinal pigment epithelial cells

(2008) Tuomas Ryhänen et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Activation of HIF-1α in exponentially growing cells via hypoxic stimulation is independent of the Akt/mTOR pathway

(2008) Frédéric Dayan et al.   JOURNAL OF CELLULAR PHYSIOLOGY

A light and electron microscopy analysis of the events leading to male sterility in Ogu-INRA CMS of rapeseed (Brassica napus)

(2008) P. Gonzalez-Melendi et al.   JOURNAL OF EXPERIMENTAL BOTANY

Suppression of autophagy precipitates neuronal cell death following low doses of methamphetamine

(2008) Roberta Castino et al.   JOURNAL OF NEUROCHEMISTRY

Role of autophagy in G2019S-LRRK2-associated neurite shortening in differentiated SH-SY5Y cells

(2008) Edward D. Plowey et al.   JOURNAL OF NEUROCHEMISTRY

Autophagy Induction and Autophagosome Clearance in Neurons: Relationship to Autophagic Pathology in Alzheimer's Disease

(2008) B. Boland et al.   JOURNAL OF NEUROSCIENCE

Inflammatory myopathies with mitochondrial pathology and protein aggregates

(2008) Peyker Temiz et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Ordered Organelle Degradation during Starvation-induced Autophagy

(2008) Anders Riis Kristensen et al.   MOLECULAR & CELLULAR PROTEOMICS

A Portrait of Tissue Phosphoprotein Stability in the Clinical Tissue Procurement Process

(2008) Virginia Espina et al.   MOLECULAR & CELLULAR PROTEOMICS

Kinase-Inactivated ULK Proteins Inhibit Autophagy via Their Conserved C-Terminal Domains Using an Atg13-Independent Mechanism

(2008) E. Y. W. Chan et al.   MOLECULAR AND CELLULAR BIOLOGY

The Chaperone-Mediated Autophagy Receptor Organizes in Dynamic Protein Complexes at the Lysosomal Membrane

(2008) U. Bandyopadhyay et al.   MOLECULAR AND CELLULAR BIOLOGY

Golgi-resident Small GTPase Rab33B Interacts with Atg16L and Modulates Autophagosome Formation

(2008) Takashi Itoh et al.   MOLECULAR BIOLOGY OF THE CELL

Atg8 Controls Phagophore Expansion during Autophagosome Formation

(2008) Zhiping Xie et al.   MOLECULAR BIOLOGY OF THE CELL

Piecemeal Microautophagy of the Nucleus Requires the Core Macroautophagy Genes

(2008) R. Krick et al.   MOLECULAR BIOLOGY OF THE CELL

An Atg4B Mutant Hampers the Lipidation of LC3 Paralogues and Causes Defects in Autophagosome Closure

(2008) Naonobu Fujita et al.   MOLECULAR BIOLOGY OF THE CELL

Beclin 1 Forms Two Distinct Phosphatidylinositol 3-Kinase Complexes with Mammalian Atg14 and UVRAG

(2008) Eisuke Itakura et al.   MOLECULAR BIOLOGY OF THE CELL

The TP53INP2 Protein Is Required for Autophagy in Mammalian Cells

(2008) Jonathan Nowak et al.   MOLECULAR BIOLOGY OF THE CELL

JNK1-Mediated Phosphorylation of Bcl-2 Regulates Starvation-Induced Autophagy

(2008) Yongjie Wei et al.   MOLECULAR CELL

AMPK Phosphorylation of Raptor Mediates a Metabolic Checkpoint

(2008) Dana M. Gwinn et al.   MOLECULAR CELL

Proteomic analysis of membrane microdomain-associated proteins in the dorsolateral prefrontal cortex in schizophrenia and bipolar disorder reveals alterations in LAMP, STXBP1 and BASP1 protein expression

(2008) ÁT Behan et al.   MOLECULAR PSYCHIATRY

Listeriolysin O allows Listeria monocytogenes replication in macrophage vacuoles

(2008) Cheryl L. Birmingham et al.   NATURE

Essential role for Nix in autophagic maturation of erythroid cells

(2008) Hector Sandoval et al.   NATURE

Mature ribosomes are selectively degraded upon starvation by an autophagy pathway requiring the Ubp3p/Bre5p ubiquitin protease

(2008) Claudine Kraft et al.   NATURE CELL BIOLOGY

Regulation of TORC1 by Rag GTPases in nutrient response

(2008) Eunjung Kim et al.   NATURE CELL BIOLOGY

Regulation of autophagy by cytoplasmic p53

(2008) Ezgi Tasdemir et al.   NATURE CELL BIOLOGY

Novel targets for Huntington's disease in an mTOR-independent autophagy pathway

(2008) Andrea Williams et al.   Nature Chemical Biology

Autophagic control of listeria through intracellular innate immune recognition in drosophila

(2008) Tamaki Yano et al.   NATURE IMMUNOLOGY

5′-triphosphate-siRNA: turning gene silencing and Rig-I activation against melanoma

(2008) Hendrik Poeck et al.   NATURE MEDICINE

Autophagic cell death: the story of a misnomer

(2008) Guido Kroemer et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Protective role of autophagy in neonatal hypoxia–ischemia induced brain injury

(2008) Silvia Carloni et al.   NEUROBIOLOGY OF DISEASE

E2F1 regulates autophagy and the transcription of autophagy genes

(2008) S Polager et al.   ONCOGENE

The ATG Autophagic Conjugation System in Maize: ATG Transcripts and Abundance of the ATG8-Lipid Adduct Are Regulated by Development and Nutrient Availability

(2008) T. Chung et al.   PLANT PHYSIOLOGY

Autophagy Plays a Role in Chloroplast Degradation during Senescence in Individually Darkened Leaves

(2008) S. Wada et al.   PLANT PHYSIOLOGY

Mobilization of Rubisco and Stroma-Localized Fluorescent Proteins of Chloroplasts to the Vacuole by an ATG Gene-Dependent Autophagic Process

(2008) H. Ishida et al.   PLANT PHYSIOLOGY

A Role for Autophagy in the Extension of Lifespan by Dietary Restriction in C. elegans

(2008) Malene Hansen et al.   PLoS Genetics

A role for the NAD-dependent deacetylase Sirt1 in the regulation of autophagy

(2008) I. H. Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Proteomic analysis of lithium-induced nephrogenic diabetes insipidus: Mechanisms for aquaporin 2 down-regulation and cellular proliferation

(2008) J. Nielsen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Rapamycin inhibits trypanosome cell growth by preventing TOR complex 2 formation

(2008) A. Barquilla et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ceramide starves cells to death by downregulating nutrient transporter proteins

(2008) G. G. Guenther et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Antagonism of E2F-1 regulated Bnip3 transcription by NF- B is essential for basal cell survival

(2008) J. Shaw et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identification of Barkor as a mammalian autophagy-specific factor for Beclin 1 and class III phosphatidylinositol 3-kinase

(2008) Q. Sun et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Autophagy-Related Proteins, LC3 and Beclin-1, in Placentas From Pregnancies Complicated by Preeclampsia

(2008) Soo-Young Oh et al.   Reproductive Sciences

Ovarian follicular atresia is mediated by heterophagy, autophagy, and apoptosis in Prochilodus argenteus and Leporinus taeniatus (Teleostei: Characiformes)

(2008) H.B. Santos et al.   THERIOGENOLOGY

Irs4p and Tax4p: Two Redundant EH Domain Proteins Involved in Autophagy

(2008) Amandine Bugnicourt et al.   TRAFFIC

The Itinerary of Autophagosomes: From Peripheral Formation to Kiss-and-Run Fusion with Lysosomes

(2008) Luca Jahreiss et al.   TRAFFIC

A179L, a viral Bcl-2 homologue, targets the core Bcl-2 apoptotic machinery and its upstream BH3 activators with selective binding restrictions for Bid and Noxa

(2008) Inmaculada Galindo et al.   VIROLOGY

Targeting lysosomal degradation induces p53-dependent cell death and prevents cancer in mouse models of lymphomagenesis

(2007) Kirsteen H. Maclean et al.   JOURNAL OF CLINICAL INVESTIGATION

The Atg1 Kinase Complex Is Involved in the Regulation of Protein Recruitment to Initiate Sequestering Vesicle Formation for Nonspecific Autophagy in Saccharomyces cerevisiae

(2007) Heesun Cheong et al.   MOLECULAR BIOLOGY OF THE CELL