β-Synuclein suppresses both the initiation and amplification steps of α-synuclein aggregation via competitive binding to surfaces

Particle-Based Monte-Carlo Simulations of Steady-State Mass Transport at Intermediate Péclet Numbers

(2016) Thomas Müller et al.   INTERNATIONAL JOURNAL OF NONLINEAR SCIENCES AND NUMERICAL SIMULATION

Molecular mechanisms of protein aggregation from global fitting of kinetic models

(2016) Georg Meisl et al.   Nature Protocols

Induction of de novo α-synuclein fibrillization in a neuronal model for Parkinson’s disease

(2016) Mohamed-Bilal Fares et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mutations associated with familial Parkinson’s disease alter the initiation and amplification steps of α-synuclein aggregation

(2016) Patrick Flagmeier et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Microfluidic Diffusion Analysis of the Sizes and Interactions of Proteins under Native Solution Conditions

(2015) Paolo Arosio et al.   ACS Nano

Lipid vesicles trigger α-synuclein aggregation by stimulating primary nucleation

(2015) Céline Galvagnion et al.   Nature Chemical Biology

A molecular chaperone breaks the catalytic cycle that generates toxic Aβ oligomers

(2015) Samuel I A Cohen et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

A molecular chaperone breaks the catalytic cycle that generates toxic Aβ oligomers

(2015) Samuel I A Cohen et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Unveiling transient protein-protein interactions that modulate inhibition of alpha-synuclein aggregation by beta-synuclein, a pre-synaptic protein that co-localizes with alpha-synuclein

(2015) Maria K. Janowska et al.   Scientific Reports

Quantitative Analysis of Diffusive Reactions at the Solid–Liquid Interface in Finite Systems

(2014) Thomas C. T. Michaels et al.   Journal of Physical Chemistry Letters

Surface Effects on Aggregation Kinetics of Amyloidogenic Peptides

(2014) Robert Vácha et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The Presence of an Air–Water Interface Affects Formation and Elongation of α-Synuclein Fibrils

(2014) Silvia Campioni et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Solution conditions determine the relative importance of nucleation and growth processes in  -synuclein aggregation

(2014) A. K. Buell et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Composition of isolated synaptic boutons reveals the amounts of vesicle trafficking proteins

(2014) B. G. Wilhelm et al.   SCIENCE

Direct observation of the three regions in α-synuclein that determine its membrane-bound behaviour

(2014) Giuliana Fusco et al.   Nature Communications

Counter-regulation of alpha- and beta-synuclein expression at the transcriptional level

(2013) Josephine A. Wright et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Direct Observation of Heterogeneous Amyloid Fibril Growth Kinetics via Two-Color Super-Resolution Microscopy

(2013) Dorothea Pinotsi et al.   NANO LETTERS

Proliferation of amyloid- 42 aggregates occurs through a secondary nucleation mechanism

(2013) S. I. A. Cohen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Rationally Designed Six-Residue Swap Generates Comparability in the Aggregation Behavior of α-Synuclein and β-Synuclein

(2012) Cintia Roodveldt et al.   BIOCHEMISTRY

Direct Observation of the Interconversion of Normal and Toxic Forms of α-Synuclein

(2012) Nunilo Cremades et al.   CELL

Quantifying Interactions of β-Synuclein and γ-Synuclein with Model Membranes

(2012) Vanessa C. Ducas et al.   JOURNAL OF MOLECULAR BIOLOGY

Membrane Curvature Induction and Tubulation Are Common Features of Synucleins and Apolipoproteins

(2010) Jobin Varkey et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

SDS-Induced Fibrillation of α-Synuclein: An Alternative Fibrillation Pathway

(2010) Lise Giehm et al.   JOURNAL OF MOLECULAR BIOLOGY

Surface Attachment of Protein Fibrils via Covalent Modification Strategies

(2010) Alexander K. Buell et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Multiple Tight Phospholipid-Binding Modes of α-Synuclein Revealed by Solution NMR Spectroscopy

(2009) Christina R. Bodner et al.   JOURNAL OF MOLECULAR BIOLOGY

Molecular determinants of the aggregation behavior of α- and β-synuclein

(2008) Robert C. Rivers et al.   PROTEIN SCIENCE