Dopamine Transporter/α-Synuclein Complexes Are Altered in the Post Mortem Caudate Putamen of Parkinson’s Disease: An In Situ Proximity Ligation Assay Study

Synapsin III is a key component of α-synuclein fibrils in Lewy bodies of PD brains

(2018) Francesca Longhena et al.   BRAIN PATHOLOGY

Alpha‐synuclein aggregates activate calcium pump SERCA leading to calcium dysregulation

(2018) Cristine Betzer et al.   EMBO REPORTS

Nigrostriatal dopamine transporter availability in early Parkinson's disease

(2018) Patrik Fazio et al.   MOVEMENT DISORDERS

In Situ Proximity Ligation Assay Reveals Co-Localization of Alpha-Synuclein and SNARE Proteins in Murine Primary Neurons

(2018) Leire Almandoz-Gil et al.   Frontiers in Neurology

Extreme disorder in an ultrahigh-affinity protein complex

(2018) Alessandro Borgia et al.   NATURE

Functional alterations of the dopaminergic and glutamatergic systems in spontaneous α-synuclein overexpressing rats

(2017) Ezia Guatteo et al.   EXPERIMENTAL NEUROLOGY

Dopamine transporter imaging does not predict the number of nigral neurons in Parkinson disease

(2017) Laura Saari et al.   NEUROLOGY

The End Is the Beginning: Parkinson’s Disease in the Light of Brain Imaging

(2017) Arianna Bellucci et al.   Frontiers in Aging Neuroscience

Axonal damage and loss of connectivity in nigrostriatal and mesolimbic dopamine pathways in early Parkinson's disease

(2017) Silvia Paola Caminiti et al.   NeuroImage-Clinical

Review: Parkinson's disease: from synaptic loss to connectome dysfunction

(2016) Arianna Bellucci et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Structural and functional properties of prefibrillar α-synuclein oligomers

(2016) Laura Pieri et al.   Scientific Reports

Direct visualization of alpha-synuclein oligomers reveals previously undetected pathology in Parkinson’s disease brain

(2015) Rosalind F. Roberts et al.   BRAIN

Dopamine Transporter Activity Is Modulated by α-Synuclein

(2015) Brittany Butler et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

 -synuclein and synapsin III cooperatively regulate synaptic function in dopamine neurons

(2015) M. Zaltieri et al.   JOURNAL OF CELL SCIENCE

The Synaptic Function of α-Synuclein

(2015) Jacqueline Burré   Journal of Parkinsons Disease

Disease duration and the integrity of the nigrostriatal system in Parkinson’s disease

(2013) Jeffrey H. Kordower et al.   BRAIN

The Clathrin-Dependent Localization of Dopamine Transporter to Surface Membranes Is Affected by α-Synuclein

(2013) Haya Kisos et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Serine 129 phosphorylation of membrane-associated α-synuclein modulates dopamine transporter function in a G protein–coupled receptor kinase–dependent manner

(2013) Susumu Hara et al.   MOLECULAR BIOLOGY OF THE CELL

Effects of exogenous alpha-synuclein on stimulated dopamine overflow in dorsal striatum

(2013) Anssi Pelkonen et al.   NEUROSCIENCE LETTERS

Mechanisms of dopamine transporter regulation in normal and disease states

(2013) Roxanne A. Vaughan et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Impaired neurotransmission caused by overexpression of  -synuclein in nigral dopamine neurons

(2012) M. Lundblad et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Phosphorylated  -Synuclein in Parkinson's Disease

(2012) Y. Wang et al.   Science Translational Medicine

Decreased reuptake of dopamine in the dorsal striatum in the absence of alpha-synuclein

(2011) Heramb Chadchankar et al.   BRAIN RESEARCH

Synuclein modulation of monoamine transporters

(2011) Adam W. Oaks et al.   FEBS LETTERS

Novel Strategies for Drug Discovery Based on Intrinsically Disordered Proteins (IDPs)

(2011) Jihua Wang et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

α-Synuclein Stimulates a Dopamine Transporter-dependent Chloride Current and Modulates the Activity of the Transporter

(2011) Jarod Swant et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Redistribution of DAT/α-Synuclein Complexes Visualized by “In Situ” Proximity Ligation Assay in Transgenic Mice Modelling Early Parkinson's Disease

(2011) Arianna Bellucci et al.   PLoS One

The synaptic pathology of α-synuclein aggregation in dementia with Lewy bodies, Parkinson’s disease and Parkinson’s disease dementia

(2010) Walter J. Schulz-Schaeffer   ACTA NEUROPATHOLOGICA

SNARE protein redistribution and synaptic failure in a transgenic mouse model of Parkinson’s disease

(2010) Pablo Garcia-Reitböck et al.   BRAIN

Regulation of dopamine transporter function by protein-protein interactions: new discoveries and methodological challenges

(2010) Jacob Eriksen et al.   JOURNAL OF NEUROCHEMISTRY

Alpha-synuclein aggregation and cell death triggered by energy deprivation and dopamine overload are counteracted by D2D3receptor activation

(2008) Arianna Bellucci et al.   JOURNAL OF NEUROCHEMISTRY

Nigral burden of α-synuclein correlates with striatal dopamine deficit

(2008) Gabor G. Kovacs et al.   MOVEMENT DISORDERS