Synapsin III is a key component of α-synuclein fibrils in Lewy bodies of PD brains

Synapsins regulate brain-derived neurotrophic factor-mediated synaptic potentiation and axon elongation by acting on membrane rafts

(2017) Hung-Teh Kao et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Tale of the Good and the Bad Cdk5: Remodeling of the Actin Cytoskeleton in the Brain

(2017) Kavita Shah et al.   MOLECULAR NEUROBIOLOGY

Synaptic vesicle glycoprotein 2C (SV2C) modulates dopamine release and is disrupted in Parkinson disease

(2017) Amy R. Dunn et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Synaptic failure and α-synuclein

(2016) Laura Calo et al.   MOVEMENT DISORDERS

Review: Parkinson's disease: from synaptic loss to connectome dysfunction

(2016) Arianna Bellucci et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Synapsin III in brain development

(2016) Laura E. Perlini et al.   Oncotarget

Direct visualization of alpha-synuclein oligomers reveals previously undetected pathology in Parkinson’s disease brain

(2015) Rosalind F. Roberts et al.   BRAIN

 -synuclein and synapsin III cooperatively regulate synaptic function in dopamine neurons

(2015) M. Zaltieri et al.   JOURNAL OF CELL SCIENCE

Cdk5 at crossroads of protein oligomerization in neurodegenerative diseases: facts and hypotheses

(2015) Anna Wilkaniec et al.   JOURNAL OF NEUROCHEMISTRY

Phosphorylation by PKA and Cdk5 Mediates the Early Effects of Synapsin III in Neuronal Morphological Maturation

(2015) A. Piccini et al.   JOURNAL OF NEUROSCIENCE

Synapsin III Acts Downstream of Semaphorin 3A/CDK5 Signaling to Regulate Radial Migration and Orientation of Pyramidal Neurons In Vivo

(2015) Laura E. Perlini et al.   Cell Reports

The Synaptic Function of α-Synuclein

(2015) Jacqueline Burré   Journal of Parkinsons Disease

The small GTPase Rab11 co-localizes with  -synuclein in intracellular inclusions and modulates its aggregation, secretion and toxicity

(2014) O. Chutna et al.   HUMAN MOLECULAR GENETICS

Rab11 modulates α-synuclein-mediated defects in synaptic transmission and behaviour

(2014) Carlo Breda et al.   HUMAN MOLECULAR GENETICS

Synucleins Regulate the Kinetics of Synaptic Vesicle Endocytosis

(2014) K. J. Vargas et al.   JOURNAL OF NEUROSCIENCE

α-Synuclein interacts with the switch region of Rab8a in a Ser129 phosphorylation-dependent manner

(2014) Guowei Yin et al.   NEUROBIOLOGY OF DISEASE

No Association of Four Candidate Genetic Variants in MnSOD and SYNIII with Parkinson's Disease in Two Chinese Populations

(2014) Wen Juan Yu et al.   PLoS One

Lewy body extracts from Parkinson disease brains trigger α-synuclein pathology and neurodegeneration in mice and monkeys

(2013) Ariadna Recasens et al.   ANNALS OF NEUROLOGY

Synaptic Dysfunction in Synucleinopathies

(2013) O Anichtchik et al.   CNS & Neurological Disorders-Drug Targets

Association of Synapsin III Gene with Adult Attention Deficit Hyperactivity Disorder

(2013) Ayşe Nur İnci Kenar et al.   DNA AND CELL BIOLOGY

Extracellular alpha-synuclein induces calpain-dependent overactivation of cyclin-dependent kinase 5 in vitro

(2013) Grzegorz A. Czapski et al.   FEBS LETTERS

Native α-synuclein induces clustering of synaptic-vesicle mimics via binding to phospholipids and synaptobrevin-2/VAMP2

(2013) Jiajie Diao et al.   eLife

Autism-related behavioral abnormalities in synapsin knockout mice

(2012) Barbara Greco et al.   BEHAVIOURAL BRAIN RESEARCH

LRRK2 interactions with α-synuclein in Parkinson’s disease brains and in cell models

(2012) Patrícia Silva Guerreiro et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

 -Synuclein Inhibits Intersynaptic Vesicle Mobility and Maintains Recycling-Pool Homeostasis

(2012) D. Scott et al.   JOURNAL OF NEUROSCIENCE

Redistribution of DAT/α-Synuclein Complexes Visualized by “In Situ” Proximity Ligation Assay in Transgenic Mice Modelling Early Parkinson's Disease

(2011) Arianna Bellucci et al.   PLoS One

Synapsin III: Role in neuronal plasticity and disease

(2011) Barbara Porton et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Cdk5: a multifaceted kinase in neurodegenerative diseases

(2011) Zelda H. Cheung et al.   TRENDS IN CELL BIOLOGY

The synaptic pathology of α-synuclein aggregation in dementia with Lewy bodies, Parkinson’s disease and Parkinson’s disease dementia

(2010) Walter J. Schulz-Schaeffer   ACTA NEUROPATHOLOGICA

SNARE protein redistribution and synaptic failure in a transgenic mouse model of Parkinson’s disease

(2010) Pablo Garcia-Reitböck et al.   BRAIN

Synapsins Differentially Control Dopamine and Serotonin Release

(2010) B. M. Kile et al.   JOURNAL OF NEUROSCIENCE

A novel mechanism of non-Aβ component of Alzheimer's disease amyloid (NAC) neurotoxicity. Interplay between p53 protein and cyclin-dependent kinase 5 (Cdk5)

(2010) Anna Kaźmierczak et al.   NEUROCHEMISTRY INTERNATIONAL

The synapsins: Key actors of synapse function and plasticity

(2010) F. Cesca et al.   PROGRESS IN NEUROBIOLOGY

 -Synuclein Promotes SNARE-Complex Assembly in Vivo and in Vitro

(2010) J. Burre et al.   SCIENCE

Brain α-synuclein accumulation in multiple system atrophy, Parkinson's disease and progressive supranuclear palsy: a comparative investigation

(2009) Junchao Tong et al.   BRAIN

Mice lacking synapsin III show abnormalities in explicit memory and conditioned fear

(2009) B. Porton et al.   GENES BRAIN AND BEHAVIOR

A critical evaluation of current staging of α-synuclein pathology in Lewy body disorders

(2008) Kurt A. Jellinger   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Proteomic identification of novel proteins associated with Lewy bodies

(2008) Qiangwei Xia   Frontiers in Bioscience-Landmark

Early involvement of synapsin III in neural progenitor cell development in the adult hippocampus

(2008) Hung-Teh Kao et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Alpha-synuclein aggregation and cell death triggered by energy deprivation and dopamine overload are counteracted by D2D3receptor activation

(2008) Arianna Bellucci et al.   JOURNAL OF NEUROCHEMISTRY

Association between synapsin III gene promoter SNPs and multiple sclerosis in Basque patients

(2008) D Otaegui et al.   Multiple Sclerosis Journal