Synapsin III deficiency hampers α-synuclein aggregation, striatal synaptic damage and nigral cell loss in an AAV-based mouse model of Parkinson’s disease
Published 2018 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Synapsin III deficiency hampers α-synuclein aggregation, striatal synaptic damage and nigral cell loss in an AAV-based mouse model of Parkinson’s disease
Authors
Keywords
Syn III, α-Synuclein aggregation, AAV, Nigrostriatal degeneration, Synaptic proteins alterations
Journal
ACTA NEUROPATHOLOGICA
Volume 136, Issue 4, Pages 621-639
Publisher
Springer Nature America, Inc
Online
2018-07-25
DOI
10.1007/s00401-018-1892-1
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Synapsin III is a key component of α-synuclein fibrils in Lewy bodies of PD brains
- (2018) Francesca Longhena et al. BRAIN PATHOLOGY
- Dopamine Transporter/α-Synuclein Complexes Are Altered in the Post Mortem Caudate Putamen of Parkinson’s Disease: An In Situ Proximity Ligation Assay Study
- (2018) Francesca Longhena et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Selective neuronal vulnerability in Parkinson disease
- (2017) D. James Surmeier et al. NATURE REVIEWS NEUROSCIENCE
- Can Valproic Acid Regulate Neurogenesis from Nestin+ Cells in the Adult Midbrain?
- (2017) Parisa Farzanehfar et al. NEUROCHEMICAL RESEARCH
- Selective lowering of synapsins induced by oligomeric α-synuclein exacerbates memory deficits
- (2017) Megan E. Larson et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The Threshold Theory for Parkinson's Disease
- (2017) Simone Engelender et al. TRENDS IN NEUROSCIENCES
- α-Synuclein Dimers Impair Vesicle Fission during Clathrin-Mediated Synaptic Vesicle Recycling
- (2017) Audrey T. Medeiros et al. Frontiers in Cellular Neuroscience
- Early synaptic dysfunction induced by α-synuclein in a rat model of Parkinson’s disease
- (2017) Jenny-Ann Phan et al. Scientific Reports
- Synucleins Have Multiple Effects on Presynaptic Architecture
- (2017) Karina J. Vargas et al. Cell Reports
- The End Is the Beginning: Parkinson’s Disease in the Light of Brain Imaging
- (2017) Arianna Bellucci et al. Frontiers in Aging Neuroscience
- Lysines, Achilles’ heel in alpha-synuclein conversion to a deadly neuronal endotoxin
- (2016) Nicoletta Plotegher et al. AGEING RESEARCH REVIEWS
- Membrane transporters as mediators of synaptic dopamine dynamics: implications for disease
- (2016) Kelly M. Lohr et al. EUROPEAN JOURNAL OF NEUROSCIENCE
- Review: Parkinson's disease: from synaptic loss to connectome dysfunction
- (2016) Arianna Bellucci et al. NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY
- Structural basis of synaptic vesicle assembly promoted by α-synuclein
- (2016) Giuliana Fusco et al. Nature Communications
- A partial lesion model of Parkinson's disease in mice – Characterization of a 6-OHDA-induced medial forebrain bundle lesion
- (2015) Jordi Boix et al. BEHAVIOURAL BRAIN RESEARCH
- Direct visualization of alpha-synuclein oligomers reveals previously undetected pathology in Parkinson’s disease brain
- (2015) Rosalind F. Roberts et al. BRAIN
- Effects of Serine 129 Phosphorylation on α-Synuclein Aggregation, Membrane Association, and Internalization
- (2015) Filsy Samuel et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- -synuclein and synapsin III cooperatively regulate synaptic function in dopamine neurons
- (2015) M. Zaltieri et al. JOURNAL OF CELL SCIENCE
- The Synaptic Function of α-Synuclein
- (2015) Jacqueline Burré Journal of Parkinsons Disease
- α-Synuclein Multimers Cluster Synaptic Vesicles and Attenuate Recycling
- (2014) Lina Wang et al. CURRENT BIOLOGY
- Protective and toxic roles of dopamine in Parkinson's disease
- (2014) Juan Segura-Aguilar et al. JOURNAL OF NEUROCHEMISTRY
- Synucleins Regulate the Kinetics of Synaptic Vesicle Endocytosis
- (2014) K. J. Vargas et al. JOURNAL OF NEUROSCIENCE
- α-Synuclein assembles into higher-order multimers upon membrane binding to promote SNARE complex formation
- (2014) Jacqueline Burré et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Synaptic vesicle morphology: a case of protein sorting?
- (2013) Kumud R Poudel et al. CURRENT OPINION IN CELL BIOLOGY
- PLK2 Modulates α-Synuclein Aggregation in Yeast and Mammalian Cells
- (2013) Elisa Basso et al. MOLECULAR NEUROBIOLOGY
- rAAV2/7 vector-mediated overexpression of alpha-synuclein in mouse substantia nigra induces protein aggregation and progressive dose-dependent neurodegeneration
- (2013) Marusela Oliveras-Salvá et al. Molecular Neurodegeneration
- Neurotransmitter Release: The Last Millisecond in the Life of a Synaptic Vesicle
- (2013) Thomas C. Südhof NEURON
- Native α-synuclein induces clustering of synaptic-vesicle mimics via binding to phospholipids and synaptobrevin-2/VAMP2
- (2013) Jiajie Diao et al. eLife
- Late-onset Parkinsonism in NF B/c-Rel-deficient mice
- (2012) C. Baiguera et al. BRAIN
- Suppression of α-synuclein toxicity and vesicle trafficking defects by phosphorylation at S129 in yeast depends on genetic context
- (2012) Vicente Sancenon et al. HUMAN MOLECULAR GENETICS
- 100 years of Lewy pathology
- (2012) Michel Goedert et al. Nature Reviews Neurology
- Impaired neurotransmission caused by overexpression of -synuclein in nigral dopamine neurons
- (2012) M. Lundblad et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Progressive neurodegenerative and behavioural changes induced by AAV-mediated overexpression of α-synuclein in midbrain dopamine neurons
- (2011) M. Decressac et al. NEUROBIOLOGY OF DISEASE
- Redistribution of DAT/α-Synuclein Complexes Visualized by “In Situ” Proximity Ligation Assay in Transgenic Mice Modelling Early Parkinson's Disease
- (2011) Arianna Bellucci et al. PLoS One
- Synapsin III: Role in neuronal plasticity and disease
- (2011) Barbara Porton et al. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
- SNARE protein redistribution and synaptic failure in a transgenic mouse model of Parkinson’s disease
- (2010) Pablo Garcia-Reitböck et al. BRAIN
- Characterisation of behavioural and neurodegenerative changes induced by intranigral 6-hydroxydopamine lesions in a mouse model of Parkinson’s disease
- (2010) Shane Grealish et al. EUROPEAN JOURNAL OF NEUROSCIENCE
- Induction of the unfolded protein response by α-synuclein in experimental models of Parkinson’s disease
- (2010) Arianna Bellucci et al. JOURNAL OF NEUROCHEMISTRY
- Synapsins Differentially Control Dopamine and Serotonin Release
- (2010) B. M. Kile et al. JOURNAL OF NEUROSCIENCE
- -Synuclein Promotes SNARE-Complex Assembly in Vivo and in Vitro
- (2010) J. Burre et al. SCIENCE
- α-Synuclein S129 Phosphorylation Mutants Do Not Alter Nigrostriatal Toxicity in a Rat Model of Parkinson Disease
- (2009) Nikolaus R. McFarland et al. JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY
- Membrane Fusion: Grappling with SNARE and SM Proteins
- (2009) T. C. Sudhof et al. SCIENCE
- Alpha-synuclein aggregation and cell death triggered by energy deprivation and dopamine overload are counteracted by D2D3receptor activation
- (2008) Arianna Bellucci et al. JOURNAL OF NEUROCHEMISTRY
- A Dopaminergic Axon Lattice in the Striatum and Its Relationship with Cortical and Thalamic Terminals
- (2008) J. Moss et al. JOURNAL OF NEUROSCIENCE
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreFind the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
Search