COVID-19: Proposing a Ketone-Based Metabolic Therapy as a Treatment to Blunt the Cytokine Storm
出版年份 2020 全文链接
标题
COVID-19: Proposing a Ketone-Based Metabolic Therapy as a Treatment to Blunt the Cytokine Storm
作者
关键词
-
出版物
Oxidative Medicine and Cellular Longevity
Volume 2020, Issue -, Pages 1-34
出版商
Hindawi Limited
发表日期
2020-09-17
DOI
10.1155/2020/6401341
参考文献
相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。- An Acetylation Switch of the NLRP3 Inflammasome Regulates Aging-Associated Chronic Inflammation and Insulin Resistance
- (2020) Ming He et al. Cell Metabolism
- Angiotensin receptor blockers as tentative SARS‐CoV‐2 therapeutics
- (2020) David Gurwitz DRUG DEVELOPMENT RESEARCH
- Butyrate alleviates oxidative stress by regulating NRF2 nuclear accumulation and H3K9/14 acetylation via GPR109A in bovine mammary epithelial cells and mammary glands
- (2020) Wenjin Guo et al. FREE RADICAL BIOLOGY AND MEDICINE
- Estrogen-Related Receptor Alpha: An Under-Appreciated Potential Target for the Treatment of Metabolic Diseases
- (2020) Madhulika Tripathi et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Receptor recognition by novel coronavirus from Wuhan: An analysis based on decade-long structural studies of SARS
- (2020) Yushun Wan et al. JOURNAL OF VIROLOGY
- Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China
- (2020) Chaolin Huang et al. LANCET
- Nitric oxide orchestrates metabolic rewiring in M1 macrophages by targeting aconitase 2 and pyruvate dehydrogenase
- (2020) Erika M. Palmieri et al. Nature Communications
- Increased Lung Catalase Activity Confers Protection Against Experimental RSV Infection
- (2020) Maria Ansar et al. Scientific Reports
- Hydroxycarboxylic Acid Receptor 2 Is a Zika Virus Restriction Factor That Can Be Induced by Zika Virus Infection Through the IRE1-XBP1 Pathway
- (2020) Xiaocao Ma et al. Frontiers in Cellular and Infection Microbiology
- Citrullination Alters the Antiviral and Immunomodulatory Activities of the Human Cathelicidin LL-37 During Rhinovirus Infection
- (2020) Víctor Casanova et al. Frontiers in Immunology
- Clinical Characteristics of COVID-19 Patients With Digestive Symptoms in Hubei, China
- (2020) Lei Pan et al. AMERICAN JOURNAL OF GASTROENTEROLOGY
- Is Low Alveolar Type II Cell SOD3 in the Lungs of Elderly Linked to the Observed Severity of COVID-19?
- (2020) Ahmed S. Abouhashem et al. ANTIOXIDANTS & REDOX SIGNALING
- Should we stimulate or suppress immune responses in COVID-19? Cytokine and anti-cytokine interventions
- (2020) Yvan Jamilloux et al. AUTOIMMUNITY REVIEWS
- COVID ‐19 infection may cause ketosis and ketoacidosis
- (2020) Juyi Li et al. DIABETES OBESITY & METABOLISM
- Lipid-Droplet Formation Drives Pathogenic Group 2 Innate Lymphoid Cells in Airway Inflammation
- (2020) Fotios Karagiannis et al. IMMUNITY
- Cytokine release syndrome in severe COVID-19: interleukin-6 receptor antagonist tocilizumab may be the key to reduce mortality
- (2020) Chi Zhang et al. INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS
- Redox Homeostasis and Metabolism in Cancer: A Complex Mechanism and Potential Targeted Therapeutics
- (2020) Alia Ghoneum et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Angiotensin‐converting enzyme‐2 ( ACE2 ), SARS‐CoV ‐2 and pathophysiology of coronavirus disease 2019 ( COVID ‐19)
- (2020) Arno R. Bourgonje et al. JOURNAL OF PATHOLOGY
- COVID-19: consider cytokine storm syndromes and immunosuppression
- (2020) Puja Mehta et al. LANCET
- COVID-19 and diabetes mellitus: What we know, how our patients should be treated now, and what should happen next
- (2020) Angeliki M. Angelidi et al. METABOLISM-CLINICAL AND EXPERIMENTAL
- Pharmacological (or Synthetic) and Nutritional Agonists of PPAR-γ as Candidates for Cytokine Storm Modulation in COVID-19 Disease
- (2020) Carmen Ciavarella et al. MOLECULES
- SARS-CoV-2 entry factors are highly expressed in nasal epithelial cells together with innate immune genes
- (2020) Waradon Sungnak et al. NATURE MEDICINE
- Melatonin: Roles in influenza, Covid‐19, and other viral infections
- (2020) George Anderson et al. REVIEWS IN MEDICAL VIROLOGY
- Defective NADPH production in mitochondrial disease complex I causes inflammation and cell death
- (2020) Eduardo Balsa et al. Nature Communications
- SGLT2 inhibition modulates NLRP3 inflammasome activity via ketones and insulin in diabetes with cardiovascular disease
- (2020) So Ra Kim et al. Nature Communications
- The Impact of Acute Ingestion of a Ketone Monoester Drink on LPS-Stimulated NLRP3 Activation in Humans with Obesity
- (2020) Helena Neudorf et al. Nutrients
- Bmal1 integrates mitochondrial metabolism and macrophage activation
- (2020) Ryan K Alexander et al. eLife
- Sodium Butyrate Abrogates the Growth and Pathogenesis of Mycobacterium bovis via Regulation of Cathelicidin (LL37) Expression and NF-κB Signaling
- (2020) Kai Zhang et al. Frontiers in Microbiology
- COVID-19 cytokine storm: the interplay between inflammation and coagulation
- (2020) Ricardo J Jose et al. Lancet Respiratory Medicine
- O-GlcNAc transferase promotes influenza A virus–induced cytokine storm by targeting interferon regulatory factor–5
- (2020) Qiming Wang et al. Science Advances
- Master Regulator Analysis of the SARS-CoV-2/Human Interactome
- (2020) Pietro H. Guzzi et al. Journal of Clinical Medicine
- Decoding SARS-CoV-2 hijacking of host mitochondria in COVID-19 pathogenesis
- (2020) Keshav K. Singh et al. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
- Antiviral activities of type I interferons to SARS-CoV-2 infection
- (2020) Emily Mantlo et al. ANTIVIRAL RESEARCH
- Interplay between NADH oxidation by complex I, glutathione redox state and sirtuin-3, and its role in the development of insulin resistance
- (2020) Christian Cortés-Rojo et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Epidemiological characteristics of coronavirus disease 2019 (COVID-19) patients in IRAN: A single center study
- (2020) Mohamad Nikpouraghdam et al. JOURNAL OF CLINICAL VIROLOGY
- The pathogenesis and treatment of the `Cytokine Storm' in COVID-19
- (2020) Qing Ye et al. JOURNAL OF INFECTION
- Bicarbonate Unlocks the Ergogenic Action of Ketone Monoester Intake in Endurance Exercise
- (2020) Chiel Poffé et al. MEDICINE AND SCIENCE IN SPORTS AND EXERCISE
- Tetrahydrobiopterin in energy metabolism and metabolic diseases
- (2020) Hyoung Kyu Kim et al. PHARMACOLOGICAL RESEARCH
- Increased Glucose Availability Attenuates Myocardial Ketone Body Utilization
- (2020) Manoja K. Brahma et al. Journal of the American Heart Association
- Letter to the editor: Unexpected high mortality in COVID-19 and diabetic ketoacidosis
- (2020) Natalia Chamorro-Pareja et al. METABOLISM-CLINICAL AND EXPERIMENTAL
- Niacin fine-tunes energy homeostasis through canonical GPR109A signaling
- (2019) Lingyan Ye et al. FASEB JOURNAL
- The “great” controlling nucleotide coenzymes
- (2019) Richard L. Veech et al. IUBMB LIFE
- Prominent action of butyrate over β-hydroxybutyrate as histone deacetylase inhibitor, transcriptional modulator and anti-inflammatory molecule
- (2019) Sabrina Chriett et al. Scientific Reports
- Cytoplasmic and Mitochondrial NADPH-Coupled Redox Systems in the Regulation of Aging
- (2019) Patrick Bradshaw Nutrients
- Novel endosomal NOX2 oxidase inhibitor ameliorates pandemic influenza A virus‐induced lung inflammation in mice
- (2019) Eunice E. To et al. RESPIROLOGY
- Oral Ketone Supplementation Acutely Increases Markers of NLRP3 Inflammasome Activation in Human Monocytes
- (2019) Helena Neudorf et al. MOLECULAR NUTRITION & FOOD RESEARCH
- The Short Chain Fatty Acid Butyrate Imprints an Antimicrobial Program in Macrophages
- (2019) Julie Schulthess et al. IMMUNITY
- Anti-inflammatory action of β-hydroxybutyrate via modulation of PGC-1α and FoxO1, mimicking calorie restriction
- (2019) Dae Hyun Kim et al. Aging-US
- Ketone ester supplementation blunts overreaching symptoms during endurance training overload
- (2019) Chiel Poffé et al. JOURNAL OF PHYSIOLOGY-LONDON
- Use of Growth Factors and Cytokines to Treat Injuries Resulting from a Radiation Public Health Emergency
- (2019) Zulmarie Perez Horta et al. RADIATION RESEARCH
- Histone Deacetylase 7 Inhibition in A Murine Model of Gram-Negative Pneumonia-Induced Acute Lung Injury
- (2019) George Kasotakis et al. SHOCK
- Low-Carb and Ketogenic Diets in Type 1 and Type 2 Diabetes
- (2019) Bolla et al. Nutrients
- Cathelicidin is a “fire alarm”, generating protective NLRP3-dependent airway epithelial cell inflammatory responses during infection with Pseudomonas aeruginosa
- (2019) Brian J. McHugh et al. PLoS Pathogens
- The impact of keto-adaptation on exercise performance and the role of metabolic-regulating cytokines
- (2019) Matthew Sherrier et al. AMERICAN JOURNAL OF CLINICAL NUTRITION
- Mitochondrial Reactive Oxygen Species Contribute to Pathological Inflammation During Influenza A Virus Infection in Mice
- (2019) Eunice E. To et al. ANTIOXIDANTS & REDOX SIGNALING
- The NLRP3 Inflammasome: An Overview of Mechanisms of Activation and Regulation
- (2019) Nathan Kelley et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Up-regulation of FOXO1 and reduced inflammation by β-hydroxybutyric acid are essential diet restriction benefits against liver injury
- (2019) Tomoyuki Miyauchi et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Rapamycin Modulate Treg/Th17 Balance via Regulating Metabolic Pathways: A Study in Mice
- (2019) Jiabi Zhang et al. TRANSPLANTATION PROCEEDINGS
- Human Antimicrobial Peptides as Therapeutics for Viral Infections
- (2019) Aslaa Ahmed et al. Viruses-Basel
- ENaC-mediated sodium influx exacerbates NLRP3-dependent inflammation in cystic fibrosis
- (2019) Thomas Scambler et al. eLife
- A ketone monoester drink reduces the glycemic response to an oral glucose challenge in individuals with obesity: a randomized trial
- (2019) Étienne Myette-Côté et al. AMERICAN JOURNAL OF CLINICAL NUTRITION
- Acute hyperketonaemia alters T-cell-related cytokine gene expression within stimulated peripheral blood mononuclear cells following prolonged exercise
- (2019) David M. Shaw et al. EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY
- Hepatic nuclear factor kappa B signaling pathway and NLR family pyrin domain containing 3 inflammasome is over-activated in ketotic dairy cows
- (2019) Taiyu Shen et al. JOURNAL OF DAIRY SCIENCE
- Inflammatory profile dysregulation in nuclear workers occupationally exposed to low-dose gamma radiation
- (2019) Nevena Aneva et al. JOURNAL OF RADIATION RESEARCH
- Ketogenic diet activates protective γδ T cell responses against influenza virus infection
- (2019) Emily L. Goldberg et al. Science Immunology
- Relationship between inorganic ion distribution, resting membrane potential, and the ΔG′ of ATP hydrolysis: a new paradigm
- (2019) Richard L. Veech et al. FASEB JOURNAL
- Ketogenesis-generated β-hydroxybutyrate is an epigenetic regulator of CD8+ T-cell memory development
- (2019) Huafeng Zhang et al. NATURE CELL BIOLOGY
- Rewiring of Glutamine Metabolism Is a Bioenergetic Adaptation of Human Cells with Mitochondrial DNA Mutations
- (2018) Qiuying Chen et al. Cell Metabolism
- Intermittent Fasting Confers Protection in CNS Autoimmunity by Altering the Gut Microbiota
- (2018) Francesca Cignarella et al. Cell Metabolism
- Glucose-6-phosphate dehydrogenase inhibition attenuates acute lung injury through reduction in NADPH oxidase-derived reactive oxygen species
- (2018) A. Nadeem et al. CLINICAL AND EXPERIMENTAL IMMUNOLOGY
- Metabolic routes in inflammation: the citrate pathway and its potential as therapeutic target
- (2018) Vittoria Infantino et al. CURRENT MEDICINAL CHEMISTRY
- Macrophages: Their role, activation and polarization in pulmonary diseases
- (2018) Shweta Arora et al. IMMUNOBIOLOGY
- Regulation of type 2 innate lymphoid cell–dependent airway hyperreactivity by butyrate
- (2018) Christina Li-Ping Thio et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- NADH Shuttling Couples Cytosolic Reductive Carboxylation of Glutamine with Glycolysis in Cells with Mitochondrial Dysfunction
- (2018) Edoardo Gaude et al. MOLECULAR CELL
- γδ T cells producing interleukin-17A regulate adipose regulatory T cell homeostasis and thermogenesis
- (2018) Ayano C. Kohlgruber et al. NATURE IMMUNOLOGY
- Angiotensin-converting enzyme in innate and adaptive immunity
- (2018) Kenneth E. Bernstein et al. Nature Reviews Nephrology
- A Ketogenic Diet Improves Mitochondrial Biogenesis and Bioenergetics via the PGC1α-SIRT3-UCP2 Axis
- (2018) Md Mahdi Hasan-Olive et al. NEUROCHEMICAL RESEARCH
- Ketogenic diet attenuates oxidative stress and inflammation after spinal cord injury by activating Nrf2 and suppressing the NF-κB signaling pathways
- (2018) Yao Lu et al. NEUROSCIENCE LETTERS
- Circulating Cytokine/Chemokine Concentrations Respond to Ionizing Radiation Doses but not Radiation Dose Rates: Granulocyte-Colony Stimulating Factor and Interleukin-18
- (2018) Juliann G. Kiang et al. RADIATION RESEARCH
- Cell fate in antiviral response arises in the crosstalk of IRF, NF-κB and JAK/STAT pathways
- (2018) Maciej Czerkies et al. Nature Communications
- The use of nutritional supplements to induce ketosis and reduce symptoms associated with keto-induction: a narrative review
- (2018) Cliff J. d C. Harvey et al. PeerJ
- Transforming Growth Factor-β and Interleukin-10 Synergistically Regulate Humoral Immunity via Modulating Metabolic Signals
- (2018) Toshihiko Komai et al. Frontiers in Immunology
- Impairment of Fatty Acid Oxidation in Alveolar Epithelial Cells Mediates Acute Lung Injury
- (2018) Huachun Cui et al. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
- Lung γδ T Cells Mediate Protective Responses during Neonatal Influenza Infection that Are Associated with Type 2 Immunity
- (2018) Xi-zhi J. Guo et al. IMMUNITY
- β-Hydroxybutyrate Elicits Favorable Mitochondrial Changes in Skeletal Muscle
- (2018) Brian Parker et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Pyruvate dehydrogenase phosphatase catalytic subunit 2 limits Th17 differentiation
- (2018) Michihito Kono et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Redox Biology of Respiratory Viral Infections
- (2018) Olga Khomich et al. Viruses-Basel
- A reduced M1-like/M2-like ratio of macrophages in healthy adipose tissue expansion during SGLT2 inhibition
- (2018) Yasutaka Miyachi et al. Scientific Reports
- G Protein-Coupled Receptor 109A and Host Microbiota Modulate Intestinal Epithelial Integrity During Sepsis
- (2018) Guangxin Chen et al. Frontiers in Immunology
- O-GlcNAc Transferase Links Glucose Metabolism to MAVS-Mediated Antiviral Innate Immunity
- (2018) Tianliang Li et al. Cell Host & Microbe
- Efferocytosis Fuels Requirements of Fatty Acid Oxidation and the Electron Transport Chain to Polarize Macrophages for Tissue Repair
- (2018) Shuang Zhang et al. Cell Metabolism
- Hepatocyte-Macrophage Acetoacetate Shuttle Protects against Tissue Fibrosis
- (2018) Patrycja Puchalska et al. Cell Metabolism
- Repression of Transcriptional Activity of Forkhead Box O1 by Histone Deacetylase Inhibitors Ameliorates Hyperglycemia in Type 2 Diabetic Rats
- (2018) Hyun Cho et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Excessive endosomal TLR signaling causes inflammatory disease in mice with defective SMCR8-WDR41-C9ORF72 complex function
- (2018) William McAlpine et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Effects of Low-to-Moderate Doses of Gamma Radiation on Mouse Hematopoietic System
- (2018) XiangHong Li et al. RADIATION RESEARCH
- HIF-1α triggers ER stress and CHOP-mediated apoptosis in alveolar epithelial cells, a key event in pulmonary fibrosis
- (2018) Eva Delbrel et al. Scientific Reports
- High-fat diet inhibits PGC-1α suppressive effect on NFκB signaling in hepatocytes
- (2017) Wermerson Assunção Barroso et al. EUROPEAN JOURNAL OF NUTRITION
- The dual role of cathelicidins in systemic inflammation
- (2017) Fabiano Pinheiro da Silva et al. IMMUNOLOGY LETTERS
- Role of the histone deacetylase inhibitor valproic acid in high-fat diet-induced hypertension via inhibition of HDAC1/angiotensin II axis
- (2017) J Choi et al. INTERNATIONAL JOURNAL OF OBESITY
- Radiation protection and mitigation potential of phenylbutyrate: delivered via oral administration
- (2017) Alexandra C. Miller et al. INTERNATIONAL JOURNAL OF RADIATION BIOLOGY
- A review of radiation countermeasures focusing on injury-specific medicinals and regulatory approval status: part I. Radiation sub-syndromes, animal models and FDA-approved countermeasures
- (2017) Vijay K. Singh et al. INTERNATIONAL JOURNAL OF RADIATION BIOLOGY
- Reactive oxygen species inhibit catalytic activity of peptidylarginine deiminase
- (2017) Dres Damgaard et al. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY
- Sodium butyrate suppresses angiotensin II-induced hypertension by inhibition of renal (pro)renin receptor and intrarenal renin–angiotensin system
- (2017) Lei Wang et al. JOURNAL OF HYPERTENSION
- The SARS-CoV Fusion Peptide Forms an Extended Bipartite Fusion Platform that Perturbs Membrane Order in a Calcium-Dependent Manner
- (2017) Alex L. Lai et al. JOURNAL OF MOLECULAR BIOLOGY
- Effects of a dietary ketone ester on hippocampal glycolytic and tricarboxylic acid cycle intermediates and amino acids in a 3xTgAD mouse model of Alzheimer's disease
- (2017) Robert J. Pawlosky et al. JOURNAL OF NEUROCHEMISTRY
- A Pck1-directed glycogen metabolic program regulates formation and maintenance of memory CD8+ T cells
- (2017) Ruihua Ma et al. NATURE CELL BIOLOGY
- FoxO1 is a regulator of MHC-II expression and anti-tumor effect of tumor-associated macrophages
- (2017) Jing-Bo Yang et al. ONCOGENE
- Cytokine storm and sepsis disease pathogenesis
- (2017) Benjamin G. Chousterman et al. Seminars in Immunopathology
- New fronts emerge in the influenza cytokine storm
- (2017) Xi-zhi J. Guo et al. Seminars in Immunopathology
- Hydroxy-Carboxylic Acid Receptor Actions in Metabolism
- (2017) Stefan Offermanns TRENDS IN ENDOCRINOLOGY AND METABOLISM
- The mito-DAMP cardiolipin blocks IL-10 production causing persistent inflammation during bacterial pneumonia
- (2017) Krishnendu Chakraborty et al. Nature Communications
- Beta-hydroxybutyrate, an endogenic NLRP3 inflammasome inhibitor, attenuates stress-induced behavioral and inflammatory responses
- (2017) Takehiko Yamanashi et al. Scientific Reports
- Nuclear translocation of HIF-1α induced by influenza A (H1N1) infection is critical to the production of proinflammatory cytokines
- (2017) Xinkun Guo et al. Emerging Microbes & Infections
- On the Metabolism of Exogenous Ketones in Humans
- (2017) Brianna J. Stubbs et al. Frontiers in Physiology
- Butyrate Conditions Human Dendritic Cells to Prime Type 1 Regulatory T Cells via both Histone Deacetylase Inhibition and G Protein-Coupled Receptor 109A Signaling
- (2017) Maria M. M. Kaisar et al. Frontiers in Immunology
- The Microbial Metabolite Butyrate Induces Expression of Th1-Associated Factors in CD4+ T Cells
- (2017) Meike Kespohl et al. Frontiers in Immunology
- Type I Interferons as Regulators of Lung Inflammation
- (2017) Spyridon Makris et al. Frontiers in Immunology
- Opposing Effects of Fasting Metabolism on Tissue Tolerance in Bacterial and Viral Inflammation
- (2016) Andrew Wang et al. CELL
- Dysregulated Type I Interferon and Inflammatory Monocyte-Macrophage Responses Cause Lethal Pneumonia in SARS-CoV-Infected Mice
- (2016) Rudragouda Channappanavar et al. Cell Host & Microbe
- Nutritional Ketosis Alters Fuel Preference and Thereby Endurance Performance in Athletes
- (2016) Pete J. Cox et al. Cell Metabolism
- Reprogramming mitochondrial metabolism in macrophages as an anti-inflammatory signal
- (2016) Evanna L. Mills et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Skeletal muscle PGC-1α modulates systemic ketone body homeostasis and ameliorates diabetic hyperketonemia in mice
- (2016) Kristoffer Svensson et al. FASEB JOURNAL
- Collectins, H-ficolin and LL-37 reduce influence viral replication in human monocytes and modulate virus-induced cytokine production
- (2016) Mitchell R White et al. Innate Immunity
- PFKFB3-Driven Macrophage Glycolytic Metabolism Is a Crucial Component of Innate Antiviral Defense
- (2016) Hui Jiang et al. JOURNAL OF IMMUNOLOGY
- Cutting Edge: Critical Role of Glycolysis in Human Plasmacytoid Dendritic Cell Antiviral Responses
- (2016) Gagan Bajwa et al. JOURNAL OF IMMUNOLOGY
- The evolution of diabetic ketoacidosis: An update of its etiology, pathogenesis and management
- (2016) Ebenezer A. Nyenwe et al. METABOLISM-CLINICAL AND EXPERIMENTAL
- Mitochondrial respiratory-chain adaptations in macrophages contribute to antibacterial host defense
- (2016) Johan Garaude et al. NATURE IMMUNOLOGY
- Epigenetic gene regulation by histone demethylases: emerging role in oncogenesis and inflammation
- (2016) MK Kang et al. ORAL DISEASES
- Cytokine Elevation in Sudden Death With Respiratory Syncytial Virus: A Case Report of 2 Children
- (2016) Y. Kakimoto et al. PEDIATRICS
- The effects of ketogenic diet on the Th17/Treg cells imbalance in patients with intractable childhood epilepsy
- (2016) Fen-Fen Ni et al. SEIZURE-EUROPEAN JOURNAL OF EPILEPSY
- Systematic review and meta-analysis reveals acutely elevated plasma cortisol following fasting but not less severe calorie restriction
- (2016) Yuko Nakamura et al. STRESS-THE INTERNATIONAL JOURNAL ON THE BIOLOGY OF STRESS
- The harmonizome: a collection of processed datasets gathered to serve and mine knowledge about genes and proteins
- (2016) Andrew D. Rouillard et al. Database-The Journal of Biological Databases and Curation
- FoxO1 regulates allergic asthmatic inflammation through regulating polarization of the macrophage inflammatory phenotype
- (2016) Sangwoon Chung et al. Oncotarget
- Changes in blood lymphocyte numbers with age in vivo and their association with the levels of cytokines/cytokine receptors
- (2016) Yun Lin et al. Immunity & Ageing
- Diminished COX-2/PGE2-Mediated Antiviral Response Due to Impaired NOX/MAPK Signaling in G6PD-Knockdown Lung Epithelial Cells
- (2016) Hsin-Ru Lin et al. PLoS One
- Lactate as substrate for mitochondrial respiration in alveolar epithelial type II cells
- (2015) Robyn G. Lottes et al. AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY
- SIRT3 Mediates Multi-Tissue Coupling for Metabolic Fuel Switching
- (2015) Kristin E. Dittenhafer-Reed et al. Cell Metabolism
- Lung epithelial NOX/DUOX and respiratory virus infections
- (2015) Nathalie Grandvaux et al. CLINICAL SCIENCE
- New insights into PGC-1 coactivators: redefining their role in the regulation of mitochondrial function and beyond
- (2015) Josep A. Villena FEBS Journal
- A Broken Krebs Cycle in Macrophages
- (2015) Luke A.J. O’Neill IMMUNITY
- Network Integration of Parallel Metabolic and Transcriptional Data Reveals Metabolic Modules that Regulate Macrophage Polarization
- (2015) Abhishek K. Jha et al. IMMUNITY
- Fasting and refeeding differentially regulate NLRP3 inflammasome activation in human subjects
- (2015) Javier Traba et al. JOURNAL OF CLINICAL INVESTIGATION
- Portrait of inflammatory response to ionizing radiation treatment
- (2015) Federica Di Maggio et al. Journal of Inflammation-London
- The ketone metabolite β-hydroxybutyrate blocks NLRP3 inflammasome–mediated inflammatory disease
- (2015) Yun-Hee Youm et al. NATURE MEDICINE
- Tissue-based map of the human proteome
- (2015) M. Uhlen et al. SCIENCE
- Angiotensins as therapeutic targets beyond heart disease
- (2015) Danielle Gomes Passos-Silva et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- Viral activation of cellular metabolism
- (2015) Erica L. Sanchez et al. VIROLOGY
- Severe acute respiratory syndrome coronavirus E protein transports calcium ions and activates the NLRP3 inflammasome
- (2015) Jose L. Nieto-Torres et al. VIROLOGY
- Glucose-6-Phosphate Dehydrogenase Enhances Antiviral Response through Downregulation of NADPH Sensor HSCARG and Upregulation of NF-κB Signaling
- (2015) Yi-Hsuan Wu et al. Viruses-Basel
- Redox regulation of FoxO transcription factors
- (2015) Lars-Oliver Klotz et al. Redox Biology
- The effect of short-chain fatty acids on human monocyte-derived dendritic cells
- (2015) Claudia Nastasi et al. Scientific Reports
- Protective effects of exogenous β-hydroxybutyrate on paraquat toxicity in rat kidney
- (2014) Teng Wei et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- A key role of the mitochondrial citrate carrier (SLC25A1) in TNFα- and IFNγ-triggered inflammation
- (2014) Vittoria Infantino et al. Biochimica et Biophysica Acta-Gene Regulatory Mechanisms
- Cathelicidin antimicrobial peptide LL-37 augments interferon-β expression and antiviral activity induced by double-stranded RNA in keratinocytes
- (2014) T. Takiguchi et al. BRITISH JOURNAL OF DERMATOLOGY
- A Nuclear Pyruvate Dehydrogenase Complex Is Important for the Generation of Acetyl-CoA and Histone Acetylation
- (2014) Gopinath Sutendra et al. CELL
- �-Hydroxybutyrate Activates the NF-κB Signaling Pathway to Promote the Expression of Pro-Inflammatory Factors in Calf Hepatocytes
- (2014) Xiaoxia Shi et al. CELLULAR PHYSIOLOGY AND BIOCHEMISTRY
- Changes in circulating cytokines and markers of muscle damage in elite cyclists during a multi-stage competition
- (2014) Alfredo Córdova Martínez et al. CLINICAL PHYSIOLOGY AND FUNCTIONAL IMAGING
- Regulation of G6PD acetylation by KAT9/SIRT2 modulates NADPH homeostasis and cell survival during oxidative stress
- (2014) Y.-P. Wang et al. EMBO JOURNAL
- Influenza A virus and TLR7 activation potentiate NOX2 oxidase-dependent ROS production in macrophages
- (2014) E. E. To et al. FREE RADICAL RESEARCH
- Activation of Gpr109a, Receptor for Niacin and the Commensal Metabolite Butyrate, Suppresses Colonic Inflammation and Carcinogenesis
- (2014) Nagendra Singh et al. IMMUNITY
- Metabolic programming and PDHK1 control CD4+ T cell subsets and inflammation
- (2014) Valerie A. Gerriets et al. JOURNAL OF CLINICAL INVESTIGATION
- Estrogen-related receptor alpha and mitochondria: tale of the titans
- (2014) Harmit S. Ranhotra JOURNAL OF RECEPTORS AND SIGNAL TRANSDUCTION
- BHBA Suppresses LPS-Induced Inflammation in BV-2 Cells by Inhibiting NF-κB Activation
- (2014) Shou-Peng Fu et al. MEDIATORS OF INFLAMMATION
- TLR-driven early glycolytic reprogramming via the kinases TBK1-IKKɛ supports the anabolic demands of dendritic cell activation
- (2014) Bart Everts et al. NATURE IMMUNOLOGY
- De novo fatty acid synthesis controls the fate between regulatory T and T helper 17 cells
- (2014) Luciana Berod et al. NATURE MEDICINE
- Diisopropylamine Dichloroacetate, a Novel Pyruvate Dehydrogenase Kinase 4 Inhibitor, as a Potential Therapeutic Agent for Metabolic Disorders and Multiorgan Failure in Severe Influenza
- (2014) Kazuhiko Yamane et al. PLoS One
- The microbial metabolite butyrate regulates intestinal macrophage function via histone deacetylase inhibition
- (2014) Pamela V. Chang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Direct Type I IFN but Not MDA5/TLR3 Activation of Dendritic Cells Is Required for Maturation and Metabolic Shift to Glycolysis after Poly IC Stimulation
- (2014) Austin Pantel et al. PLOS BIOLOGY
- Ketone esters increase brown fat in mice and overcome insulin resistance in other tissues in the rat
- (2013) Richard L. Veech Annals of the New York Academy of Sciences
- Mucosal Reactive Oxygen Species Are Required for Antiviral Response: Role of Duox in Influenza A Virus Infection
- (2013) Monika Strengert et al. ANTIOXIDANTS & REDOX SIGNALING
- IFNβ/TNFα synergism induces a non-canonical STAT2/IRF9-dependent pathway triggering a novel DUOX2 NADPH Oxidase-mediated airway antiviral response
- (2013) Karin Fink et al. CELL RESEARCH
- FoxO3 coordinates metabolic pathways to maintain redox balance in neural stem cells
- (2013) Hyeonju Yeo et al. EMBO JOURNAL
- The role of HCA2 (GPR109A) in regulating macrophage function
- (2013) Kambiz Zandi-Nejad et al. FASEB JOURNAL
- Butyrate Attenuates Inflammation and Lipolysis Generated by the Interaction of Adipocytes and Macrophages
- (2013) Hideo Ohira et al. Journal of Atherosclerosis and Thrombosis
- TLR3-Triggered Reactive Oxygen Species Contribute to Inflammatory Responses by Activating Signal Transducer and Activator of Transcription-1
- (2013) C.-S. Yang et al. JOURNAL OF IMMUNOLOGY
- Histone deacetylase inhibitors up-regulate LL-37 expression independent of toll-like receptor mediated signalling in airway epithelial cells
- (2013) Quan Liu et al. Journal of Inflammation-London
- Metabolites produced by commensal bacteria promote peripheral regulatory T-cell generation
- (2013) Nicholas Arpaia et al. NATURE
- Succinate is an inflammatory signal that induces IL-1β through HIF-1α
- (2013) G. M. Tannahill et al. NATURE
- Complex I generated, mitochondrial matrix-directed superoxide is released from the mitochondria through voltage dependent anion channels
- (2012) Michael S. Lustgarten et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Nrf2 Redirects Glucose and Glutamine into Anabolic Pathways in Metabolic Reprogramming
- (2012) Yoichiro Mitsuishi et al. CANCER CELL
- Mitochondrial dysfunction and oxidative stress activate inflammasomes: impact on the aging process and age-related diseases
- (2012) Antero Salminen et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Response patterns of cytokines/chemokines in two murine strains after irradiation
- (2012) Mei Zhang et al. CYTOKINE
- Mitochondrial biogenesis and increased uncoupling protein 1 in brown adipose tissue of mice fed a ketone ester diet
- (2012) Shireesh Srivastava et al. FASEB JOURNAL
- A ketogenic diet increases brown adipose tissue mitochondrial proteins and UCP1 levels in mice
- (2012) Shireesh Srivastava et al. IUBMB LIFE
- Into the Eye of the Cytokine Storm
- (2012) J. R. Tisoncik et al. MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS
- Control of Proinflammatory Gene Programs by Regulated Trimethylation and Demethylation of Histone H4K20
- (2012) Joshua D. Stender et al. MOLECULAR CELL
- Treatment of acute metabolic acidosis: a pathophysiologic approach
- (2012) Jeffrey A. Kraut et al. Nature Reviews Nephrology
- Cytokines in Radiobiological Responses: A Review
- (2012) Dörthe Schaue et al. RADIATION RESEARCH
- Suppression of Oxidative Stress by -Hydroxybutyrate, an Endogenous Histone Deacetylase Inhibitor
- (2012) T. Shimazu et al. SCIENCE
- Proliferative and Antiapoptotic Signaling Stimulated by Nuclear-Localized PDK1 Results in Oncogenesis
- (2012) C. K. Kikani et al. Science Signaling
- New genes that extend Caenorhabditis elegans’ lifespan in response to reproductive signals
- (2011) Mark McCormick et al. AGING CELL
- Nadph oxidase regulates alveolar epithelial sodium channel activity and lung fluid balance in vivo via O2− signaling
- (2011) Preston Goodson et al. AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY
- Kv7 potassium channels in airway smooth muscle cells: signal transduction intermediates and pharmacological targets for bronchodilator therapy
- (2011) Lioubov I. Brueggemann et al. AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY
- TGF-β signaling via Smad4 drives IL-10 production in effector Th1 cells and reduces T-cell trafficking in EAE
- (2011) David J. Huss et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Mitochondrial reactive oxygen species drive proinflammatory cytokine production: Figure 1.
- (2011) Edwina Naik et al. JOURNAL OF EXPERIMENTAL MEDICINE
- The biochemistry of ketogenesis and its role in weight management, neurological disease and oxidative stress
- (2011) Peter Andrew C. McPherson et al. JOURNAL OF PHYSIOLOGY AND BIOCHEMISTRY
- A nuclear factor-κB signaling pathway via protein kinase C δ regulates replication of respiratory syncytial virus in polarized normal human nasal epithelial cells
- (2011) Tomoyuki Masaki et al. MOLECULAR BIOLOGY OF THE CELL
- Inhibition of Nox2 Oxidase Activity Ameliorates Influenza A Virus-Induced Lung Inflammation
- (2011) Ross Vlahos et al. PLoS Pathogens
- Rac1-mediated NADPH oxidase release of O2− regulates epithelial sodium channel activity in the alveolar epithelium
- (2010) Yoshizumi Takemura et al. AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY
- Constitutive NADPH-Dependent Electron Transferase Activity of the Nox4 Dehydrogenase Domain
- (2010) Yukio Nisimoto et al. BIOCHEMISTRY
- Sirt3 Mediates Reduction of Oxidative Damage and Prevention of Age-Related Hearing Loss under Caloric Restriction
- (2010) Shinichi Someya et al. CELL
- Calorie Restriction Reduces Oxidative Stress by SIRT3-Mediated SOD2 Activation
- (2010) Xiaolei Qiu et al. Cell Metabolism
- Deacetylation of FoxO by Sirt1 Plays an Essential Role in Mediating Starvation-Induced Autophagy in Cardiac Myocytes
- (2010) Nirmala Hariharan et al. CIRCULATION RESEARCH
- FoxO1 regulates Tlr4 inflammatory pathway signalling in macrophages
- (2010) WuQiang Fan et al. EMBO JOURNAL
- Original Article: Peroxisome proliferator-activated receptor and AMP-activated protein kinase agonists protect against lethal influenza virus challenge in mice
- (2010) Carson E. Moseley et al. Influenza and Other Respiratory Viruses
- Blockade of Dendritic Cell Development by Bacterial Fermentation Products Butyrate and Propionate through a Transporter (Slc5a8)-dependent Inhibition of Histone Deacetylases
- (2010) Nagendra Singh et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Peroxisome Proliferator-activated Receptor γ Coactivator 1α (PGC-1α) Promotes Skeletal Muscle Lipid Refuelingin Vivoby Activatingde NovoLipogenesis and the Pentose Phosphate Pathway
- (2010) Serge Summermatter et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Respiratory Syncytial Virus-Mediated NF- B p65 Phosphorylation at Serine 536 Is Dependent on RIG-I, TRAF6, and IKK
- (2010) F. Yoboua et al. JOURNAL OF VIROLOGY
- Toll-like receptor-3-induced mitochondrial dysfunction in cultured human hepatocytes
- (2010) Siamak Djafarzadeh et al. MITOCHONDRION
- The anti-inflammatory and immunosuppressive effects of glucocorticoids, recent developments and mechanistic insights
- (2010) Agnes E. Coutinho et al. MOLECULAR AND CELLULAR ENDOCRINOLOGY
- Requirement of NOX2 and Reactive Oxygen Species for Efficient RIG-I-Mediated Antiviral Response through Regulation of MAVS Expression
- (2010) Anton Soucy-Faulkner et al. PLoS Pathogens
- Mental Morbidities and Chronic Fatigue in Severe Acute Respiratory Syndrome Survivors
- (2009) Marco Ho-Bun Lam ARCHIVES OF INTERNAL MEDICINE
- GPR109A Is a G-protein-Coupled Receptor for the Bacterial Fermentation Product Butyrate and Functions as a Tumor Suppressor in Colon
- (2009) M. Thangaraju et al. CANCER RESEARCH
- Jmjd3 contributes to the control of gene expression in LPS-activated macrophages
- (2009) Francesca De Santa et al. EMBO JOURNAL
- The TOM complex is involved in the release of superoxide anion from mitochondria
- (2009) Małgorzata Budzińska et al. JOURNAL OF BIOENERGETICS AND BIOMEMBRANES
- Mutual Dependence of Foxo3a and PGC-1α in the Induction of Oxidative Stress Genes
- (2009) Yolanda Olmos et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- IL-6 and Serum Amyloid A Synergy Mediates Angiotensin II-Induced Muscle Wasting
- (2009) L. Zhang et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- Superoxide dismutase 3, extracellular (SOD3) variants and lung function
- (2009) Koustav Ganguly et al. PHYSIOLOGICAL GENOMICS
- MAVS-Mediated Apoptosis and Its Inhibition by Viral Proteins
- (2009) Yu Lei et al. PLoS One
- Identification of novel targets for PGC-1α and histone deacetylase inhibitors in neuroblastoma cells
- (2008) Rita M. Cowell et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- How mitochondria produce reactive oxygen species
- (2008) Michael P. Murphy BIOCHEMICAL JOURNAL
- Identification of Oxidative Stress and Toll-like Receptor 4 Signaling as a Key Pathway of Acute Lung Injury
- (2008) Yumiko Imai et al. CELL
- T cell subset-specific susceptibility to aging
- (2008) Marta Czesnikiewicz-Guzik et al. CLINICAL IMMUNOLOGY
- Transcriptional Control of Energy Homeostasis by the Estrogen-Related Receptors
- (2008) Vincent Giguère ENDOCRINE REVIEWS
- TNF-induced mitochondrial damage: a link between mitochondrial complex I activity and left ventricular dysfunction
- (2008) Nithya Mariappan et al. FREE RADICAL BIOLOGY AND MEDICINE
- Angiotensin II activates the Smad pathway during epithelial mesenchymal transdifferentiation
- (2008) Gisselle Carvajal et al. KIDNEY INTERNATIONAL
- Nitric Oxide Donor, ( )-S-Nitroso-N-acetylpenicillamine, Stabilizes Transactive Hypoxia-Inducible Factor-1 by Inhibiting von Hippel-Lindau Recruitment and Asparagine Hydroxylation
- (2008) Y.-K. Park et al. MOLECULAR PHARMACOLOGY
- A role for the mitochondrial deacetylase Sirt3 in regulating energy homeostasis
- (2008) B.-H. Ahn et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Nonclassical secretion of human catalase on the surface of CHO cells is more efficient than classical secretion
- (2007) Zuyong He et al. CELL BIOLOGY INTERNATIONAL
Add your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload NowCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now